Danio rerio

54 known processes

glra1

glycine receptor, alpha 1

(Aliases: [a]Z1)

glra1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis GO:0000902 289 0.545
response to abiotic stimulus GO:0009628 122 0.400
negative regulation of sequestering of calcium ion GO:0051283 4 0.399
sensory organ development GO:0007423 393 0.381
eye development GO:0001654 277 0.364
sequestering of metal ion GO:0051238 3 0.310
release of sequestered calcium ion into cytosol GO:0051209 3 0.297
response to temperature stimulus GO:0009266 15 0.269
response to drug GO:0042493 3 0.224
cell projection morphogenesis GO:0048858 244 0.224
cell projection organization GO:0030030 284 0.203
regulation of sequestering of calcium ion GO:0051282 4 0.194
sequestering of calcium ion GO:0051208 3 0.175
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.175
calcium ion transport into cytosol GO:0060402 3 0.173
cellular component movement GO:0006928 335 0.171
axon guidance GO:0007411 86 0.168
regulation of biological quality GO:0065008 263 0.164
Mouse
neuron differentiation GO:0030182 353 0.161
regulation of primary metabolic process GO:0080090 311 0.151
negative regulation of biological process GO:0048519 304 0.150
system process GO:0003008 185 0.143
Mouse
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.140
response to stress GO:0006950 263 0.139
response to chemical GO:0042221 320 0.132
cellular component morphogenesis GO:0032989 336 0.132
cell morphogenesis involved in differentiation GO:0000904 195 0.130
cognition GO:0050890 1 0.129
cell part morphogenesis GO:0032990 246 0.123
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.120
cytosolic calcium ion transport GO:0060401 3 0.120
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.119
regulation of rna biosynthetic process GO:2001141 213 0.116
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.115
organic substance biosynthetic process GO:1901576 289 0.114
neuron neuron synaptic transmission GO:0007270 1 0.114
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.114
hepatic duct development GO:0061011 2 0.110
heterocycle metabolic process GO:0046483 290 0.109
aging GO:0007568 2 0.104
response to endogenous stimulus GO:0009719 83 0.098
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.097
ion homeostasis GO:0050801 41 0.095
neuron projection guidance GO:0097485 86 0.092
transmembrane transport GO:0055085 120 0.091
chemotaxis GO:0006935 104 0.091
adult behavior GO:0030534 2 0.090
Mouse
gall bladder development GO:0061010 1 0.089
regulation of circadian rhythm GO:0042752 4 0.087
sensory organ morphogenesis GO:0090596 200 0.085
axon development GO:0061564 166 0.085
cellular aromatic compound metabolic process GO:0006725 295 0.084
regulation of neurogenesis GO:0050767 87 0.084
axonogenesis GO:0007409 152 0.081
camera type eye development GO:0043010 222 0.081
circadian sleep wake cycle process GO:0022410 2 0.078
gland development GO:0048732 143 0.078
eye morphogenesis GO:0048592 144 0.078
regulation of multicellular organism growth GO:0040014 4 0.077
heterocycle biosynthetic process GO:0018130 215 0.075
organelle organization GO:0006996 227 0.074
heart development GO:0007507 313 0.073
sensory perception of chemical stimulus GO:0007606 3 0.073
regulation of multicellular organismal process GO:0051239 277 0.073
response to external stimulus GO:0009605 264 0.072
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.070
response to nicotine GO:0035094 2 0.069
regulation of cellular biosynthetic process GO:0031326 245 0.069
positive regulation of biological process GO:0048518 253 0.069
circadian sleep wake cycle sleep GO:0050802 1 0.067
regulation of metabolic process GO:0019222 359 0.067
mesenchyme development GO:0060485 127 0.067
rna biosynthetic process GO:0032774 181 0.066
cellular calcium ion homeostasis GO:0006874 13 0.063
cellular biosynthetic process GO:0044249 286 0.062
sleep GO:0030431 1 0.060
nitrogen compound transport GO:0071705 23 0.060
alpha amino acid metabolic process GO:1901605 3 0.059
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.059
regulation of catalytic activity GO:0050790 55 0.059
regulation of developmental process GO:0050793 247 0.059
cation homeostasis GO:0055080 33 0.058
negative regulation of protein kinase b signaling GO:0051898 2 0.058
determination of heart left right asymmetry GO:0061371 117 0.058
tube morphogenesis GO:0035239 349 0.057
response to inorganic substance GO:0010035 38 0.057
multicellular organism growth GO:0035264 4 0.056
sensory perception GO:0007600 39 0.056
Mouse
entrainment of circadian clock GO:0009649 2 0.055
neuron projection morphogenesis GO:0048812 161 0.055
cation transmembrane transport GO:0098655 65 0.055
regulation of system process GO:0044057 40 0.054
Mouse
anterior head development GO:0097065 2 0.054
regulation of localization GO:0032879 104 0.054
regulation of nucleic acid templated transcription GO:1903506 213 0.054
cation transport GO:0006812 81 0.053
establishment of localization GO:0051234 244 0.049
positive regulation of protein complex assembly GO:0031334 2 0.049
biosynthetic process GO:0009058 294 0.049
hormone secretion GO:0046879 2 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.048
cell cell signaling GO:0007267 52 0.048
Mouse
ion transmembrane transport GO:0034220 91 0.048
chordate embryonic development GO:0043009 271 0.048
neuron projection development GO:0031175 180 0.047
macromolecule biosynthetic process GO:0009059 227 0.047
divalent inorganic cation homeostasis GO:0072507 22 0.046
developmental growth GO:0048589 166 0.046
maintenance of location GO:0051235 4 0.046
regulation of hormone secretion GO:0046883 2 0.045
neuron projection extension GO:1990138 45 0.045
retina development in camera type eye GO:0060041 146 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.045
taxis GO:0042330 109 0.044
stem cell differentiation GO:0048863 117 0.044
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.044
hair cell differentiation GO:0035315 32 0.043
axon extension GO:0048675 45 0.043
regulation of cellular metabolic process GO:0031323 320 0.043
endocrine system development GO:0035270 65 0.041
circadian sleep wake cycle GO:0042745 2 0.041
pancreas development GO:0031016 84 0.041
response to hydrogen peroxide GO:0042542 3 0.041
regulation of transcription dna templated GO:0006355 213 0.040
regulation of cell communication GO:0010646 232 0.040
cellular response to external stimulus GO:0071496 2 0.039
inorganic ion transmembrane transport GO:0098660 57 0.039
negative regulation of signaling GO:0023057 96 0.038
modification dependent protein catabolic process GO:0019941 3 0.038
regulation of cell differentiation GO:0045595 142 0.038
chemical homeostasis GO:0048878 49 0.038
inorganic cation transmembrane transport GO:0098662 50 0.037
regulation of circadian sleep wake cycle GO:0042749 1 0.037
regulation of cell development GO:0060284 100 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
generation of neurons GO:0048699 385 0.036
response to radiation GO:0009314 51 0.036
determination of bilateral symmetry GO:0009855 204 0.035
cardiac cell fate commitment GO:0060911 1 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
nitrogen compound metabolic process GO:0006807 319 0.035
regulation of anterior head development GO:2000742 2 0.034
small molecule metabolic process GO:0044281 77 0.034
pigmentation GO:0043473 85 0.034
central nervous system neuron development GO:0021954 29 0.033
regulation of skeletal muscle tissue development GO:0048641 4 0.033
response to hormone GO:0009725 48 0.033
regionalization GO:0003002 274 0.033
peptide transport GO:0015833 1 0.033
determination of left right symmetry GO:0007368 179 0.032
protein metabolic process GO:0019538 183 0.032
synaptic transmission cholinergic GO:0007271 4 0.032
regulation of transporter activity GO:0032409 2 0.032
calcium ion homeostasis GO:0055074 19 0.032
cellular cation homeostasis GO:0030003 17 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
nucleic acid templated transcription GO:0097659 181 0.032
homeostatic process GO:0042592 142 0.032
regulation of systemic arterial blood pressure GO:0003073 1 0.031
regulation of biosynthetic process GO:0009889 250 0.031
negative regulation of feeding behavior GO:2000252 2 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
transcription dna templated GO:0006351 181 0.031
blood vessel development GO:0001568 246 0.031
immune system development GO:0002520 191 0.030
spinal cord anterior posterior patterning GO:0021512 1 0.030
growth plate cartilage morphogenesis GO:0003422 1 0.030
single organism localization GO:1902578 225 0.030
neuron development GO:0048666 262 0.030
neurotransmitter transport GO:0006836 2 0.030
lateral line system development GO:0048925 76 0.029
digestive tract development GO:0048565 265 0.029
myeloid cell differentiation GO:0030099 86 0.029
positive regulation of metabolic process GO:0009893 108 0.029
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.029
response to metal ion GO:0010038 34 0.028
cellular divalent inorganic cation homeostasis GO:0072503 13 0.028
positive regulation of macromolecule metabolic process GO:0010604 93 0.028
transport GO:0006810 220 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
embryonic digestive tract morphogenesis GO:0048557 3 0.028
regulation of stem cell differentiation GO:2000736 4 0.028
positive regulation of biosynthetic process GO:0009891 68 0.028
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.028
cellular localization GO:0051641 97 0.028
Zebrafish Mouse
negative regulation of cellular process GO:0048523 283 0.027
ear development GO:0043583 127 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
neuromast development GO:0048884 46 0.027
regulation of response to stimulus GO:0048583 269 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
developmental programmed cell death GO:0010623 4 0.026
apoptotic process involved in development GO:1902742 2 0.026
regulation of molecular function GO:0065009 70 0.026
response to alkaloid GO:0043279 2 0.026
rna metabolic process GO:0016070 219 0.025
ion transport GO:0006811 114 0.025
multi organism process GO:0051704 134 0.025
Mouse
angiogenesis GO:0001525 158 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
membrane repolarization GO:0086009 2 0.024
aromatic compound biosynthetic process GO:0019438 217 0.024
myofibril assembly GO:0030239 48 0.024
negative regulation of cell death GO:0060548 60 0.024
regulation of cellular component organization GO:0051128 86 0.024
embryonic organ development GO:0048568 381 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
muscle structure development GO:0061061 196 0.024
mediolateral intercalation GO:0060031 3 0.023
regulation of protein transport GO:0051223 3 0.023
positive regulation of multicellular organismal process GO:0051240 52 0.023
regulation of anatomical structure size GO:0090066 33 0.023
hormone transport GO:0009914 2 0.023
nucleotide metabolic process GO:0009117 28 0.023
heart looping GO:0001947 94 0.023
death GO:0016265 121 0.023
locomotory behavior GO:0007626 34 0.022
Mouse
central nervous system neuron differentiation GO:0021953 74 0.022
digestive system development GO:0055123 289 0.022
monoamine transport GO:0015844 1 0.022
specification of symmetry GO:0009799 204 0.022
regulation of response to nutrient levels GO:0032107 1 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.022
nucleoside phosphate metabolic process GO:0006753 28 0.021
single organism transport GO:0044765 206 0.021
single organism biosynthetic process GO:0044711 71 0.021
cellular metal ion homeostasis GO:0006875 16 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
negative regulation of homeostatic process GO:0032845 5 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of gene expression GO:0010468 265 0.021
thrombocyte differentiation GO:0002574 4 0.020
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
macroautophagy GO:0016236 1 0.020
convergent extension GO:0060026 118 0.020
positive regulation of cellular process GO:0048522 201 0.020
signal transduction GO:0007165 455 0.020
response to organic cyclic compound GO:0014070 51 0.019
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.019
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.019
female sex differentiation GO:0046660 4 0.019
larval development GO:0002164 2 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
positive regulation of blood circulation GO:1903524 2 0.019
response to organic substance GO:0010033 153 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
cellular protein catabolic process GO:0044257 4 0.019
growth GO:0040007 174 0.018
regulation of protein metabolic process GO:0051246 56 0.018
regulation of signaling GO:0023051 235 0.018
positive regulation of transport GO:0051050 2 0.018
carbohydrate homeostasis GO:0033500 1 0.018
heart contraction GO:0060047 71 0.018
cellular ion homeostasis GO:0006873 17 0.018
forebrain cell migration GO:0021885 1 0.018
negative regulation of developmental process GO:0051093 65 0.017
protein targeting to nucleus GO:0044744 3 0.017
negative regulation of protein transport GO:0051224 3 0.017
cellular chemical homeostasis GO:0055082 17 0.017
anterior posterior pattern specification GO:0009952 152 0.017
negative regulation of cell communication GO:0010648 96 0.017
lateral line development GO:0048882 66 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
embryonic digestive tract development GO:0048566 4 0.017
regulation of cell size GO:0008361 29 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
embryonic organ morphogenesis GO:0048562 274 0.016
positive regulation of striated muscle tissue development GO:0045844 1 0.016
hemopoiesis GO:0030097 183 0.016
phosphorus metabolic process GO:0006793 109 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.016
regulation of extent of cell growth GO:0061387 29 0.016
response to glucose GO:0009749 3 0.016
purine nucleotide metabolic process GO:0006163 27 0.016
protein heterooligomerization GO:0051291 1 0.016
vasculature development GO:0001944 278 0.016
female gonad development GO:0008585 4 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
response to heat GO:0009408 6 0.015
regulation of axon extension GO:0030516 24 0.015
intracellular signal transduction GO:0035556 85 0.015
forebrain development GO:0030900 96 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.015
regulation of binding GO:0051098 3 0.015
negative regulation of wnt signaling pathway GO:0030178 30 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
gene expression GO:0010467 252 0.015
protein modification process GO:0036211 100 0.015
metal ion homeostasis GO:0055065 26 0.015
organic substance transport GO:0071702 58 0.015
cellular response to nutrient levels GO:0031669 2 0.015
response to light stimulus GO:0009416 46 0.015
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.015
response to uv GO:0009411 3 0.015
regulation of nervous system development GO:0051960 90 0.014
apoptotic process involved in morphogenesis GO:0060561 2 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
muscle hypertrophy GO:0014896 2 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
negative regulation of signal transduction GO:0009968 94 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
inner ear development GO:0048839 126 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
response to hypoxia GO:0001666 25 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
regulation of cell fate commitment GO:0010453 22 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
positive regulation of signaling GO:0023056 56 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
organelle localization GO:0051640 49 0.014
protein localization to nucleus GO:0034504 3 0.013
positive regulation of catabolic process GO:0009896 4 0.013
positive regulation of epithelial cell differentiation GO:0030858 2 0.013
positive regulation of rna metabolic process GO:0051254 59 0.013
cellular response to organic cyclic compound GO:0071407 38 0.013
nuclear import GO:0051170 3 0.013
protein localization GO:0008104 40 0.013
Zebrafish
embryonic heart tube development GO:0035050 133 0.013
response to nitrogen compound GO:1901698 19 0.013
blood vessel morphogenesis GO:0048514 216 0.013
hepatocyte proliferation GO:0072574 2 0.013
central nervous system development GO:0007417 387 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
wound healing GO:0042060 90 0.013
specification of organ identity GO:0010092 2 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
positive regulation of muscle tissue development GO:1901863 1 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
positive regulation of secretion GO:0051047 1 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
development of primary female sexual characteristics GO:0046545 4 0.012
single organism behavior GO:0044708 24 0.012
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
mechanosensory behavior GO:0007638 2 0.012
single organism cellular localization GO:1902580 46 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
response to food GO:0032094 1 0.012
positive regulation of cell communication GO:0010647 56 0.012
fin regeneration GO:0031101 51 0.012
cell motility GO:0048870 244 0.012
regulation of membrane potential GO:0042391 23 0.012
Mouse
protein import into nucleus GO:0006606 3 0.012
epithelial cell differentiation GO:0030855 116 0.012
specification of axis polarity GO:0065001 4 0.012
macromolecule modification GO:0043412 111 0.012
cell cycle arrest GO:0007050 1 0.012
endocardium morphogenesis GO:0003160 4 0.012
cytokinesis GO:0000910 3 0.012
cellular response to starvation GO:0009267 1 0.012
response to decreased oxygen levels GO:0036293 25 0.012
positive regulation of cell cycle GO:0045787 3 0.012
regulation of hormone levels GO:0010817 21 0.012
oxoacid metabolic process GO:0043436 31 0.012
neural tube patterning GO:0021532 33 0.011
locomotion GO:0040011 313 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of cellular component movement GO:0051270 55 0.011
locomotor rhythm GO:0045475 3 0.011
cellular response to radiation GO:0071478 4 0.011
response to wounding GO:0009611 116 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
chromosome organization GO:0051276 31 0.011
cellular homeostasis GO:0019725 26 0.011
regulation of locomotion GO:0040012 55 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
collagen fibril organization GO:0030199 1 0.011
rhythmic process GO:0048511 21 0.011
segmentation GO:0035282 97 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
swim bladder maturation GO:0048796 5 0.011
regulation of axonogenesis GO:0050770 32 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
motor neuron axon guidance GO:0008045 23 0.010
regulation of blood pressure GO:0008217 1 0.010
chloride transport GO:0006821 8 0.010
regulation of reproductive process GO:2000241 4 0.010
positive regulation of gene expression GO:0010628 71 0.010
localization of cell GO:0051674 244 0.010
convergent extension involved in organogenesis GO:0060029 10 0.010
protein import GO:0017038 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
sensory system development GO:0048880 76 0.010

glra1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.158
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022
osteochondrodysplasia DOID:2256 0 0.014
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
disease of cellular proliferation DOID:14566 0 0.011