Danio rerio

0 known processes

gps1

G protein pathway suppressor 1

(Aliases: zgc:154082,im:7145572,im:6909260)

gps1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.439
cellular protein catabolic process GO:0044257 4 0.334
modification dependent macromolecule catabolic process GO:0043632 3 0.272
modification dependent protein catabolic process GO:0019941 3 0.263
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.252
cellular macromolecule metabolic process GO:0044260 391 0.210
Human Fly
aging GO:0007568 2 0.180
protein metabolic process GO:0019538 183 0.174
Human Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.157
Worm
single organism organelle organization GO:1902589 199 0.141
regulation of gene expression GO:0010468 265 0.132
Fly
transport GO:0006810 220 0.132
response to nutrient GO:0007584 3 0.124
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.115
regulation of metabolic process GO:0019222 359 0.107
Fly
reproduction GO:0000003 40 0.106
Worm
proteasomal protein catabolic process GO:0010498 2 0.098
ubiquitin dependent protein catabolic process GO:0006511 3 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.096
Fly
single fertilization GO:0007338 3 0.093
locomotion GO:0040011 313 0.092
stem cell division GO:0017145 1 0.085
cellular component morphogenesis GO:0032989 336 0.082
sensory organ development GO:0007423 393 0.080
regulation of cell communication GO:0010646 232 0.078
heterocycle biosynthetic process GO:0018130 215 0.077
single organism metabolic process GO:0044710 217 0.076
protein localization to nucleus GO:0034504 3 0.075
neuron differentiation GO:0030182 353 0.071
regulation of meiotic cell cycle GO:0051445 1 0.065
positive regulation of transport GO:0051050 2 0.065
protein modification process GO:0036211 100 0.063
Human Fly
cellular protein metabolic process GO:0044267 129 0.063
Human Fly
cellular component movement GO:0006928 335 0.061
organelle organization GO:0006996 227 0.061
cellular response to external stimulus GO:0071496 2 0.061
cell cycle process GO:0022402 53 0.061
Worm Fly
gene expression GO:0010467 252 0.060
Fly
cell division GO:0051301 20 0.060
Worm
response to stress GO:0006950 263 0.060
Fly
immune system process GO:0002376 241 0.057
mitotic dna damage checkpoint GO:0044773 4 0.056
Fly
meiotic nuclear division GO:0007126 4 0.055
signal transduction GO:0007165 455 0.055
protein polyubiquitination GO:0000209 4 0.054
generation of neurons GO:0048699 385 0.054
cellular response to nutrient levels GO:0031669 2 0.053
cell migration GO:0016477 237 0.052
eye development GO:0001654 277 0.052
g2 dna damage checkpoint GO:0031572 3 0.051
Fly
cellular component biogenesis GO:0044085 178 0.051
organic cyclic compound metabolic process GO:1901360 301 0.049
protein acetylation GO:0006473 2 0.047
multi organism process GO:0051704 134 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.046
nuclear transport GO:0051169 4 0.046
cytokinesis GO:0000910 3 0.046
Worm
mitotic cell cycle GO:0000278 64 0.045
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.044
response to external stimulus GO:0009605 264 0.043
macromolecule modification GO:0043412 111 0.043
Human Fly
fertilization GO:0009566 3 0.042
localization of cell GO:0051674 244 0.042
response to drug GO:0042493 3 0.042
positive regulation of cell cycle GO:0045787 3 0.042
positive regulation of cellular process GO:0048522 201 0.041
negative regulation of metabolic process GO:0009892 86 0.041
cellular protein modification process GO:0006464 100 0.041
Human Fly
stem cell proliferation GO:0072089 4 0.040
mitotic dna integrity checkpoint GO:0044774 4 0.040
Fly
cellular amine metabolic process GO:0044106 2 0.040
mitotic g2 dna damage checkpoint GO:0007095 3 0.040
Fly
amine metabolic process GO:0009308 2 0.040
positive regulation of biological process GO:0048518 253 0.040
phosphate containing compound metabolic process GO:0006796 108 0.039
apoptotic process GO:0006915 116 0.039
cell part morphogenesis GO:0032990 246 0.038
chemotaxis GO:0006935 104 0.037
cellular ketone metabolic process GO:0042180 11 0.037
negative regulation of signal transduction GO:0009968 94 0.037
cell projection organization GO:0030030 284 0.037
cellular response to extracellular stimulus GO:0031668 2 0.037
regulation of protein localization to nucleus GO:1900180 2 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
protein targeting to nucleus GO:0044744 3 0.036
cellular macromolecule catabolic process GO:0044265 12 0.036
translational initiation GO:0006413 3 0.036
rna localization GO:0006403 4 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
regulation of chromosome segregation GO:0051983 1 0.035
sexual reproduction GO:0019953 36 0.035
cell motility GO:0048870 244 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
negative regulation of biological process GO:0048519 304 0.034
Fly
regulation of cellular amine metabolic process GO:0033238 0 0.034
protein dephosphorylation GO:0006470 3 0.034
intracellular signal transduction GO:0035556 85 0.034
establishment of localization GO:0051234 244 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.034
lipid storage GO:0019915 1 0.033
regulation of protein targeting GO:1903533 2 0.033
multicellular organism growth GO:0035264 4 0.033
regulation of protein catabolic process GO:0042176 1 0.033
regulation of signal transduction GO:0009966 225 0.033
lateral inhibition GO:0046331 1 0.033
Fly
carboxylic acid metabolic process GO:0019752 22 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
protein import into nucleus GO:0006606 3 0.032
oxoacid metabolic process GO:0043436 31 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
phosphorus metabolic process GO:0006793 109 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
intracellular mrna localization GO:0008298 1 0.031
aromatic compound biosynthetic process GO:0019438 217 0.030
biosynthetic process GO:0009058 294 0.030
regulation of neural precursor cell proliferation GO:2000177 3 0.030
maintenance of location GO:0051235 4 0.030
single organism nuclear import GO:1902593 3 0.030
regulation of protein transport GO:0051223 3 0.029
nuclear import GO:0051170 3 0.029
single organism reproductive process GO:0044702 40 0.029
Worm
response to chemical GO:0042221 320 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
phagocytosis GO:0006909 3 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
small molecule metabolic process GO:0044281 77 0.029
cell morphogenesis GO:0000902 289 0.028
regulation of primary metabolic process GO:0080090 311 0.028
negative regulation of catabolic process GO:0009895 3 0.028
neuron projection development GO:0031175 180 0.028
negative regulation of nuclear division GO:0051784 3 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
protein stabilization GO:0050821 2 0.028
Fly
programmed cell death GO:0012501 119 0.028
regulation of stem cell proliferation GO:0072091 2 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
negative regulation of gene expression GO:0010629 65 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
mitochondrion organization GO:0007005 4 0.027
protein import GO:0017038 3 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
transcription dna templated GO:0006351 181 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
death GO:0016265 121 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.026
multi organism reproductive process GO:0044703 36 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
neuroblast proliferation GO:0007405 2 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
chromatin organization GO:0006325 22 0.025
regulation of transcription dna templated GO:0006355 213 0.025
establishment or maintenance of cell polarity GO:0007163 29 0.024
cell death GO:0008219 121 0.024
cellular biosynthetic process GO:0044249 286 0.024
mitotic g2 m transition checkpoint GO:0044818 3 0.024
Fly
positive regulation of catabolic process GO:0009896 4 0.024
macromolecular complex assembly GO:0065003 35 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
regulation of developmental process GO:0050793 247 0.024
proteolysis GO:0006508 38 0.024
cell projection morphogenesis GO:0048858 244 0.024
regulation of cell cycle GO:0051726 52 0.024
Fly
meiosis i GO:0007127 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
single organism transport GO:0044765 206 0.023
regulation of biological quality GO:0065008 263 0.023
Fly
meiotic cell cycle process GO:1903046 3 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
single organism localization GO:1902578 225 0.023
regulation of mitotic cell cycle phase transition GO:1901990 8 0.023
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.022
cellular response to stress GO:0033554 62 0.022
Fly
regulation of protein import into nucleus GO:0042306 2 0.022
developmental growth GO:0048589 166 0.022
ncrna catabolic process GO:0034661 1 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
peptidyl lysine acetylation GO:0018394 2 0.022
regulation of response to stimulus GO:0048583 269 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
negative regulation of response to stimulus GO:0048585 104 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
rna metabolic process GO:0016070 219 0.021
neuron projection morphogenesis GO:0048812 161 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
phosphorylation GO:0016310 69 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
negative regulation of neural precursor cell proliferation GO:2000178 1 0.021
neuron development GO:0048666 262 0.021
dna templated transcription elongation GO:0006354 3 0.021
protein localization to plasma membrane GO:0072659 1 0.021
camera type eye development GO:0043010 222 0.021
growth GO:0040007 174 0.020
cell cycle GO:0007049 93 0.020
Worm Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
cellular component disassembly GO:0022411 1 0.020
meiotic chromosome segregation GO:0045132 3 0.020
response to biotic stimulus GO:0009607 97 0.020
regulation of biosynthetic process GO:0009889 250 0.020
anterior posterior pattern specification GO:0009952 152 0.020
axonogenesis GO:0007409 152 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
digestive system development GO:0055123 289 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
regulation of protein metabolic process GO:0051246 56 0.020
cell fate commitment GO:0045165 99 0.020
Fly
morphogenesis of an epithelium GO:0002009 333 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.019
organelle fission GO:0048285 23 0.019
autophagy GO:0006914 4 0.019
positive regulation of translation GO:0045727 1 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
heterocycle metabolic process GO:0046483 290 0.019
negative regulation of signaling GO:0023057 96 0.018
regulation of signaling GO:0023051 235 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.018
negative regulation of mitosis GO:0045839 3 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
negative regulation of chromosome organization GO:2001251 1 0.018
somatic cell dna recombination GO:0016444 1 0.018
response to organic substance GO:0010033 153 0.018
chromosome organization GO:0051276 31 0.018
response to wounding GO:0009611 116 0.018
organic acid metabolic process GO:0006082 31 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
regulation of cell activation GO:0050865 1 0.018
muscle structure development GO:0061061 196 0.018
negative regulation of cell communication GO:0010648 96 0.017
cellular response to starvation GO:0009267 1 0.017
viral process GO:0016032 1 0.017
double strand break repair GO:0006302 3 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of cell activation GO:0050867 1 0.017
negative regulation of ras protein signal transduction GO:0046580 1 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
response to hexose GO:0009746 3 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
interspecies interaction between organisms GO:0044419 4 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of organelle organization GO:0033043 29 0.016
positive regulation of multi organism process GO:0043902 3 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
response to monosaccharide GO:0034284 3 0.016
centrosome organization GO:0051297 1 0.016
immune system development GO:0002520 191 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
cell cycle phase transition GO:0044770 9 0.016
Fly
positive regulation of secretion GO:0051047 1 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
cell cell recognition GO:0009988 1 0.015
regulation of cell division GO:0051302 12 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
double strand break repair via homologous recombination GO:0000724 1 0.015
regionalization GO:0003002 274 0.015
reproductive process GO:0022414 40 0.015
Worm
positive regulation of secretion by cell GO:1903532 1 0.015
dna templated transcription initiation GO:0006352 1 0.015
hormone transport GO:0009914 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of synapse organization GO:0050807 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
response to corticosteroid GO:0031960 1 0.015
organic substance catabolic process GO:1901575 28 0.015
sister chromatid cohesion GO:0007062 2 0.015
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.015
regulation of cell death GO:0010941 103 0.015
protein modification by small protein conjugation or removal GO:0070647 14 0.015
Human Fly
spliceosomal snrnp assembly GO:0000387 2 0.015
rrna catabolic process GO:0016075 1 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
regulation of organ growth GO:0046620 3 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
cell proliferation GO:0008283 80 0.014
response to ketone GO:1901654 1 0.014
response to glucose GO:0009749 3 0.014
response to other organism GO:0051707 97 0.014
cellular localization GO:0051641 97 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
organelle assembly GO:0070925 110 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
spindle assembly GO:0051225 2 0.014
cellular response to nutrient GO:0031670 1 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
sex determination GO:0007530 1 0.014
taxis GO:0042330 109 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
nuclear export GO:0051168 1 0.013
organic substance biosynthetic process GO:1901576 289 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
membrane fusion GO:0061025 2 0.013
meiotic spindle organization GO:0000212 1 0.013
blood vessel development GO:0001568 246 0.013
rna biosynthetic process GO:0032774 181 0.013
response to glucocorticoid GO:0051384 1 0.013
posttranscriptional gene silencing GO:0016441 3 0.013
activation of mapk activity GO:0000187 3 0.013
dna metabolic process GO:0006259 27 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.013
regulation of nuclear division GO:0051783 9 0.013
atp catabolic process GO:0006200 4 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
neuron projection guidance GO:0097485 86 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
protein phosphorylation GO:0006468 47 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
mitotic cell cycle process GO:1903047 48 0.013
Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
cell substrate junction assembly GO:0007044 2 0.013
multicellular organism reproduction GO:0032504 35 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
neural precursor cell proliferation GO:0061351 20 0.012
response to carbohydrate GO:0009743 3 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
posttranscriptional gene silencing by rna GO:0035194 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
macroautophagy GO:0016236 1 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
cognition GO:0050890 1 0.012
gtp metabolic process GO:0046039 4 0.012
response to abiotic stimulus GO:0009628 122 0.012
regulation of catalytic activity GO:0050790 55 0.012
carbohydrate homeostasis GO:0033500 1 0.012
chordate embryonic development GO:0043009 271 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of glucose import GO:0046324 1 0.012
regulation of protein complex assembly GO:0043254 3 0.012
recombinational repair GO:0000725 1 0.012
nucleic acid templated transcription GO:0097659 181 0.012
cellular component assembly GO:0022607 170 0.012
retina development in camera type eye GO:0060041 146 0.012
vasculature development GO:0001944 278 0.012
antimicrobial humoral response GO:0019730 2 0.012
microtubule based process GO:0007017 60 0.012
macromolecular complex disassembly GO:0032984 1 0.012
nuclear migration GO:0007097 3 0.012
female sex differentiation GO:0046660 4 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
response to bacterium GO:0009617 58 0.012
microtubule organizing center organization GO:0031023 1 0.012
regulation of glucose transport GO:0010827 1 0.012
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
gamete generation GO:0007276 33 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
response to uv GO:0009411 3 0.011
catabolic process GO:0009056 32 0.011
spermatid differentiation GO:0048515 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of immune effector process GO:0002699 3 0.011
skeletal system development GO:0001501 181 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
macromolecule localization GO:0033036 54 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
gtp catabolic process GO:0006184 2 0.011
multi organism cellular process GO:0044764 2 0.011
covalent chromatin modification GO:0016569 20 0.011
ameboidal type cell migration GO:0001667 143 0.011
dna biosynthetic process GO:0071897 3 0.011
regulation of cell development GO:0060284 100 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
protein complex disassembly GO:0043241 1 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
mitotic nuclear division GO:0007067 18 0.011
behavior GO:0007610 74 0.011
establishment of localization in cell GO:0051649 77 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.010
developmental programmed cell death GO:0010623 4 0.010
nucleic acid transport GO:0050657 2 0.010
compound eye development GO:0048749 2 0.010
regulation of cell proliferation GO:0042127 37 0.010
vacuolar transport GO:0007034 2 0.010
regulation of cellular component organization GO:0051128 86 0.010
regulation of molecular function GO:0065009 70 0.010
positive regulation of protein kinase b signaling GO:0051897 1 0.010
cellular response to organic substance GO:0071310 105 0.010
protein acylation GO:0043543 3 0.010
cytoplasm organization GO:0007028 4 0.010
female gonad development GO:0008585 4 0.010
positive regulation of metabolic process GO:0009893 108 0.010
single organism membrane fusion GO:0044801 2 0.010
gene silencing by rna GO:0031047 4 0.010
regulation of synapse assembly GO:0051963 3 0.010
chemosensory behavior GO:0007635 1 0.010

gps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.023
disease of anatomical entity DOID:7 0 0.012