Danio rerio

0 known processes

gpx4b

glutathione peroxidase 4b

(Aliases: PHGPxb,cb692,zgc:110018,MGC110018)

gpx4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.409
aging GO:0007568 2 0.311
hydrogen peroxide metabolic process GO:0042743 2 0.215
oxidation reduction process GO:0055114 41 0.197
establishment of localization GO:0051234 244 0.192
response to hydrogen peroxide GO:0042542 3 0.112
cellular aromatic compound metabolic process GO:0006725 295 0.103
multicellular organism growth GO:0035264 4 0.102
regulation of multicellular organismal process GO:0051239 277 0.099
stem cell proliferation GO:0072089 4 0.095
cellular macromolecule metabolic process GO:0044260 391 0.089
generation of neurons GO:0048699 385 0.083
positive regulation of biological process GO:0048518 253 0.065
apoptotic process GO:0006915 116 0.062
cellular component morphogenesis GO:0032989 336 0.061
nitrogen compound metabolic process GO:0006807 319 0.060
aromatic compound biosynthetic process GO:0019438 217 0.059
regulation of multicellular organism growth GO:0040014 4 0.058
amine metabolic process GO:0009308 2 0.057
cellular nitrogen compound metabolic process GO:0034641 290 0.054
regulation of cell death GO:0010941 103 0.052
positive regulation of cellular amine metabolic process GO:0033240 0 0.052
immune system process GO:0002376 241 0.051
death GO:0016265 121 0.051
organic cyclic compound metabolic process GO:1901360 301 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.049
inorganic cation transmembrane transport GO:0098662 50 0.049
nucleic acid metabolic process GO:0090304 244 0.048
cellular response to reactive oxygen species GO:0034614 2 0.048
single organism metabolic process GO:0044710 217 0.047
response to inorganic substance GO:0010035 38 0.046
cellular component biogenesis GO:0044085 178 0.046
organic cyclic compound biosynthetic process GO:1901362 223 0.046
neuroblast proliferation GO:0007405 2 0.045
organonitrogen compound metabolic process GO:1901564 74 0.042
organic acid metabolic process GO:0006082 31 0.042
inorganic ion transmembrane transport GO:0098660 57 0.042
multi organism process GO:0051704 134 0.041
response to oxidative stress GO:0006979 11 0.041
cellular respiration GO:0045333 3 0.041
cellular amine metabolic process GO:0044106 2 0.040
peptidyl serine phosphorylation GO:0018105 1 0.039
programmed cell death GO:0012501 119 0.039
protein metabolic process GO:0019538 183 0.039
transmembrane transport GO:0055085 120 0.038
cellular ketone metabolic process GO:0042180 11 0.038
single organism localization GO:1902578 225 0.038
adult behavior GO:0030534 2 0.037
negative regulation of cellular process GO:0048523 283 0.037
regulation of binding GO:0051098 3 0.037
rna biosynthetic process GO:0032774 181 0.036
regulation of biological quality GO:0065008 263 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
cellular amino acid metabolic process GO:0006520 7 0.035
growth GO:0040007 174 0.034
response to external stimulus GO:0009605 264 0.034
heterocycle biosynthetic process GO:0018130 215 0.034
response to stress GO:0006950 263 0.033
regulation of programmed cell death GO:0043067 101 0.032
embryonic organ development GO:0048568 381 0.032
regulation of apoptotic process GO:0042981 98 0.032
regulation of protein localization to nucleus GO:1900180 2 0.031
developmental growth GO:0048589 166 0.031
cellular protein modification process GO:0006464 100 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
response to chemical GO:0042221 320 0.031
biosynthetic process GO:0009058 294 0.031
neuron differentiation GO:0030182 353 0.031
single organism nuclear import GO:1902593 3 0.030
morphogenesis of an epithelium GO:0002009 333 0.030
mitochondrion organization GO:0007005 4 0.030
carboxylic acid metabolic process GO:0019752 22 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
heterocycle metabolic process GO:0046483 290 0.029
cell morphogenesis GO:0000902 289 0.029
regulation of cysteine type endopeptidase activity GO:2000116 21 0.029
protein import GO:0017038 3 0.029
macromolecule biosynthetic process GO:0009059 227 0.028
tube morphogenesis GO:0035239 349 0.028
actin polymerization or depolymerization GO:0008154 2 0.028
peptidyl serine modification GO:0018209 2 0.028
meiotic cell cycle process GO:1903046 3 0.028
negative regulation of protein transport GO:0051224 3 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.027
cell part morphogenesis GO:0032990 246 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
transcription dna templated GO:0006351 181 0.027
negative regulation of cell death GO:0060548 60 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of protein transport GO:0051223 3 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
small molecule metabolic process GO:0044281 77 0.026
organic substance biosynthetic process GO:1901576 289 0.025
oxidoreduction coenzyme metabolic process GO:0006733 1 0.025
cation transmembrane transport GO:0098655 65 0.025
regulation of transmembrane transporter activity GO:0022898 2 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
regulation of peptidase activity GO:0052547 23 0.024
cell proliferation GO:0008283 80 0.024
rna metabolic process GO:0016070 219 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
nucleic acid templated transcription GO:0097659 181 0.024
cellular response to chemical stimulus GO:0070887 157 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
cellular component movement GO:0006928 335 0.023
regulation of rna biosynthetic process GO:2001141 213 0.022
collagen biosynthetic process GO:0032964 2 0.021
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.021
respiratory electron transport chain GO:0022904 2 0.021
cilium organization GO:0044782 71 0.021
oxoacid metabolic process GO:0043436 31 0.021
determination of left right symmetry GO:0007368 179 0.020
microtubule organizing center organization GO:0031023 1 0.019
digestive tract development GO:0048565 265 0.019
cilium morphogenesis GO:0060271 85 0.019
cell death GO:0008219 121 0.019
sensory organ development GO:0007423 393 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.019
regulation of endopeptidase activity GO:0052548 23 0.019
single organism transport GO:0044765 206 0.019
transport GO:0006810 220 0.019
monovalent inorganic cation transport GO:0015672 42 0.018
cellular biosynthetic process GO:0044249 286 0.018
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
negative regulation of biological process GO:0048519 304 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
nuclear import GO:0051170 3 0.017
response to other organism GO:0051707 97 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
immune system development GO:0002520 191 0.017
positive regulation of cell cycle GO:0045787 3 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
reproductive process GO:0022414 40 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
meiotic nuclear division GO:0007126 4 0.016
protein import into nucleus GO:0006606 3 0.016
regulation of cell projection assembly GO:0060491 4 0.016
regulation of developmental process GO:0050793 247 0.016
regulation of signal transduction GO:0009966 225 0.016
homeostasis of number of cells within a tissue GO:0048873 4 0.015
negative regulation of gene expression GO:0010629 65 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
regulation of neurogenesis GO:0050767 87 0.015
maintenance of location GO:0051235 4 0.015
heart looping GO:0001947 94 0.015
signal transduction GO:0007165 455 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
protein secretion GO:0009306 1 0.015
regulation of multicellular organismal metabolic process GO:0044246 2 0.015
regulation of protein targeting GO:1903533 2 0.015
regulation of nervous system development GO:0051960 90 0.015
protein acetylation GO:0006473 2 0.014
response to drug GO:0042493 3 0.014
neurotransmitter transport GO:0006836 2 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of transporter activity GO:0032409 2 0.014
hemopoiesis GO:0030097 183 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
regulation of blood pressure GO:0008217 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of metal ion transport GO:0010959 4 0.013
actin filament based movement GO:0030048 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
positive regulation of transport GO:0051050 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regulation of signaling GO:0023051 235 0.013
gene expression GO:0010467 252 0.013
digestive system development GO:0055123 289 0.012
response to oxygen containing compound GO:1901700 55 0.012
regulation of transcription dna templated GO:0006355 213 0.012
chordate embryonic development GO:0043009 271 0.012
nuclear transport GO:0051169 4 0.012
negative regulation of neural precursor cell proliferation GO:2000178 1 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
behavior GO:0007610 74 0.012
cell projection morphogenesis GO:0048858 244 0.012
lipid storage GO:0019915 1 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
single organism organelle organization GO:1902589 199 0.011
positive regulation of cellular process GO:0048522 201 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
negative regulation of endopeptidase activity GO:0010951 10 0.011
positive regulation of developmental process GO:0051094 50 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
regulation of growth GO:0040008 42 0.011
cell projection assembly GO:0030031 64 0.011
actin mediated cell contraction GO:0070252 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
protein localization to nucleus GO:0034504 3 0.011
liver development GO:0001889 96 0.011
regulation of sodium ion transport GO:0002028 2 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
phagocytosis engulfment GO:0006911 1 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
cellular protein metabolic process GO:0044267 129 0.011
ion transport GO:0006811 114 0.010
retina development in camera type eye GO:0060041 146 0.010
phosphorus metabolic process GO:0006793 109 0.010
cell death in response to oxidative stress GO:0036473 2 0.010
regulation of cytokine production GO:0001817 3 0.010
positive regulation of multicellular organismal process GO:0051240 52 0.010
regulation of rna metabolic process GO:0051252 224 0.010
cellular response to radiation GO:0071478 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010

gpx4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010