Danio rerio

44 known processes

gria2a

glutamate receptor, ionotropic, AMPA 2a

(Aliases: zfGRIA2[a],glur2a,gria2.1)

gria2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
directional locomotion GO:0033058 1 0.998
Worm
cognition GO:0050890 1 0.987
Worm
sensory perception of chemical stimulus GO:0007606 3 0.970
Worm
neuron neuron synaptic transmission GO:0007270 1 0.935
Rat Worm
anterior lateral line development GO:0048899 5 0.892
anterior lateral line system development GO:0048898 9 0.887
glutamate receptor signaling pathway GO:0007215 1 0.881
Human Mouse Rat Worm
receptor recycling GO:0001881 4 0.692
Rat
skeletal system development GO:0001501 181 0.590
regulation of synaptic plasticity GO:0048167 1 0.488
mechanosensory lateral line system development GO:0048881 49 0.456
sensory system development GO:0048880 76 0.452
embryonic organ development GO:0048568 381 0.429
receptor internalization GO:0031623 2 0.424
Rat
mesenchyme development GO:0060485 127 0.380
response to osmotic stress GO:0006970 11 0.349
Worm
taxis GO:0042330 109 0.322
Worm
larval development GO:0002164 2 0.315
Worm
transport GO:0006810 220 0.315
Human Mouse Rat Worm
thigmotaxis GO:0001966 5 0.308
Worm
synaptic transmission GO:0007268 35 0.305
Mouse Rat Worm
lateral line development GO:0048882 66 0.304
embryonic organ morphogenesis GO:0048562 274 0.245
embryonic skeletal system development GO:0048706 97 0.228
posterior lateral line system development GO:0048915 46 0.227
neural crest cell differentiation GO:0014033 72 0.212
stem cell development GO:0048864 82 0.205
locomotory behavior GO:0007626 34 0.193
chordate embryonic development GO:0043009 271 0.188
mesenchymal cell differentiation GO:0048762 87 0.179
single organism localization GO:1902578 225 0.176
Human Mouse Rat Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.176
positive regulation of biological process GO:0048518 253 0.174
Rat
regulation of signaling GO:0023051 235 0.168
Rat
embryo development ending in birth or egg hatching GO:0009792 271 0.163
single organism behavior GO:0044708 24 0.158
Worm
receptor metabolic process GO:0043112 6 0.156
Rat
behavior GO:0007610 74 0.148
Worm
regulation of dendrite development GO:0050773 3 0.137
neurological system process GO:0050877 62 0.136
Worm
signal transduction GO:0007165 455 0.136
Human Mouse Rat Worm
regulation of dendrite morphogenesis GO:0048814 3 0.130
single organism transport GO:0044765 206 0.130
Human Mouse Rat Worm
response to mechanical stimulus GO:0009612 24 0.130
Worm
cell cell signaling GO:0007267 52 0.128
Mouse Rat Worm
system process GO:0003008 185 0.126
Worm
fertilization GO:0009566 3 0.122
neurotransmitter transport GO:0006836 2 0.112
positive regulation of cellular process GO:0048522 201 0.110
Rat
multicellular organism growth GO:0035264 4 0.109
skeletal system morphogenesis GO:0048705 102 0.108
renal tubule morphogenesis GO:0061333 1 0.105
cellular component assembly GO:0022607 170 0.099
Rat
stem cell differentiation GO:0048863 117 0.099
hormone transport GO:0009914 2 0.097
response to abiotic stimulus GO:0009628 122 0.093
Worm
protein metabolic process GO:0019538 183 0.092
neuron differentiation GO:0030182 353 0.091
central nervous system development GO:0007417 387 0.090
regulation of cell communication GO:0010646 232 0.089
Rat
regulation of neuron migration GO:2001222 2 0.089
response to stress GO:0006950 263 0.087
Worm
mechanosensory behavior GO:0007638 2 0.087
cell projection morphogenesis GO:0048858 244 0.084
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.083
regulation of multicellular organismal development GO:2000026 223 0.082
regulation of synaptic transmission GO:0050804 4 0.078
Rat
nephron tubule morphogenesis GO:0072078 1 0.077
regulation of cell development GO:0060284 100 0.076
cell projection organization GO:0030030 284 0.076
ion transport GO:0006811 114 0.075
Human Mouse Rat Worm
cellular aromatic compound metabolic process GO:0006725 295 0.074
neuron projection morphogenesis GO:0048812 161 0.069
branching morphogenesis of a nerve GO:0048755 4 0.069
single organism metabolic process GO:0044710 217 0.067
Rat
hormone secretion GO:0046879 2 0.067
regulation of synapse organization GO:0050807 3 0.066
regulation of multicellular organism growth GO:0040014 4 0.065
regulation of biological quality GO:0065008 263 0.065
central nervous system projection neuron axonogenesis GO:0021952 15 0.065
neural crest cell development GO:0014032 62 0.062
regulation of cellular metabolic process GO:0031323 320 0.062
Rat
response to drug GO:0042493 3 0.061
regulation of tube size GO:0035150 2 0.060
regulation of locomotion GO:0040012 55 0.059
Worm
cellular protein metabolic process GO:0044267 129 0.058
ion transmembrane transport GO:0034220 91 0.056
Human Mouse Rat Worm
embryonic skeletal system morphogenesis GO:0048704 93 0.056
gastrulation GO:0007369 208 0.055
peptide transport GO:0015833 1 0.053
establishment of localization GO:0051234 244 0.053
Human Mouse Rat Worm
nephron morphogenesis GO:0072028 2 0.053
neuron development GO:0048666 262 0.053
positive regulation of transport GO:0051050 2 0.051
blood vessel development GO:0001568 246 0.051
lateral line system development GO:0048925 76 0.050
sensory perception of touch GO:0050975 2 0.049
vesicle mediated transport GO:0016192 22 0.049
Rat
mesenchymal cell development GO:0014031 78 0.049
cell morphogenesis involved in differentiation GO:0000904 195 0.049
tube morphogenesis GO:0035239 349 0.048
endocytosis GO:0006897 16 0.047
Rat
synaptic vesicle transport GO:0048489 1 0.047
cellular biosynthetic process GO:0044249 286 0.046
pronuclear migration GO:0035046 1 0.046
cellular macromolecule metabolic process GO:0044260 391 0.046
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.046
Rat
negative regulation of secretion GO:0051048 2 0.045
locomotion GO:0040011 313 0.043
Worm
dopaminergic neuron differentiation GO:0071542 14 0.042
meiosis i GO:0007127 1 0.042
positive regulation of cell cycle GO:0045787 3 0.042
cell surface receptor signaling pathway GO:0007166 325 0.041
Human Mouse Rat Worm
regulation of axonogenesis GO:0050770 32 0.041
generation of neurons GO:0048699 385 0.041
cell motility GO:0048870 244 0.039
nitrogen compound metabolic process GO:0006807 319 0.038
axon development GO:0061564 166 0.037
negative regulation of synapse assembly GO:0051964 2 0.037
meiotic nuclear division GO:0007126 4 0.037
negative regulation of signaling GO:0023057 96 0.037
cellular response to external stimulus GO:0071496 2 0.036
response to monosaccharide GO:0034284 3 0.036
sensory perception GO:0007600 39 0.035
Worm
regulation of cell differentiation GO:0045595 142 0.035
regulation of growth GO:0040008 42 0.034
membrane hyperpolarization GO:0060081 1 0.034
protein n linked glycosylation GO:0006487 1 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.033
regulation of neuron differentiation GO:0045664 56 0.033
regulation of response to nutrient levels GO:0032107 1 0.033
regulation of molecular function GO:0065009 70 0.033
synaptic transmission glycinergic GO:0060012 1 0.033
digestive system development GO:0055123 289 0.032
response to chemical GO:0042221 320 0.032
Rat
retrograde axon cargo transport GO:0008090 1 0.032
cellular response to nutrient levels GO:0031669 2 0.031
glucose homeostasis GO:0042593 1 0.031
neuron projection development GO:0031175 180 0.031
response to hexose GO:0009746 3 0.031
negative regulation of cellular process GO:0048523 283 0.030
regulation of reproductive process GO:2000241 4 0.030
synaptic vesicle localization GO:0097479 1 0.030
centrosome cycle GO:0007098 1 0.029
reflex GO:0060004 2 0.029
regulation of neuron projection development GO:0010975 40 0.029
cellular response to starvation GO:0009267 1 0.029
regulation of neuronal synaptic plasticity GO:0048168 1 0.029
single fertilization GO:0007338 3 0.028
regulation of hormone secretion GO:0046883 2 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
pole plasm assembly GO:0007315 4 0.028
dicarboxylic acid metabolic process GO:0043648 1 0.028
nucleic acid metabolic process GO:0090304 244 0.028
rna localization GO:0006403 4 0.027
phasic smooth muscle contraction GO:0014821 1 0.026
pancreatic d cell differentiation GO:0003311 2 0.026
negative regulation of biological process GO:0048519 304 0.026
locomotor rhythm GO:0045475 3 0.026
positive regulation of secretion GO:0051047 1 0.025
central nervous system neuron axonogenesis GO:0021955 18 0.025
negative regulation of reproductive process GO:2000242 3 0.025
negative regulation of cell communication GO:0010648 96 0.025
regulation of cell cycle GO:0051726 52 0.025
regulation of gene expression GO:0010468 265 0.025
gabaergic neuron differentiation GO:0097154 2 0.024
digestive tract development GO:0048565 265 0.024
regulation of synaptic vesicle transport GO:1902803 1 0.024
synaptic vesicle recycling GO:0036465 1 0.024
establishment of synaptic vesicle localization GO:0097480 1 0.024
regulation of cell death GO:0010941 103 0.023
regulation of nervous system development GO:0051960 90 0.023
nephron epithelium morphogenesis GO:0072088 1 0.023
gene expression GO:0010467 252 0.023
regulation of primary metabolic process GO:0080090 311 0.023
establishment of vesicle localization GO:0051650 24 0.023
brain development GO:0007420 293 0.022
reciprocal dna recombination GO:0035825 1 0.022
cellular nitrogen compound metabolic process GO:0034641 290 0.022
axon midline choice point recognition GO:0016199 4 0.022
microtubule organizing center organization GO:0031023 1 0.022
aging GO:0007568 2 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
chemosensory behavior GO:0007635 1 0.022
modification dependent protein catabolic process GO:0019941 3 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
forebrain cell migration GO:0021885 1 0.021
regulation of synapse assembly GO:0051963 3 0.021
response to carbohydrate GO:0009743 3 0.021
cellular component maintenance GO:0043954 3 0.021
atp catabolic process GO:0006200 4 0.021
response to external stimulus GO:0009605 264 0.021
Worm
organonitrogen compound metabolic process GO:1901564 74 0.021
organelle fusion GO:0048284 3 0.020
pigment granule localization GO:0051875 25 0.020
postsynaptic membrane organization GO:0001941 3 0.020
lipid storage GO:0019915 1 0.020
intracellular mrna localization GO:0008298 1 0.020
limbic system development GO:0021761 16 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
regulation of metabolic process GO:0019222 359 0.019
Rat
convergent extension GO:0060026 118 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
macromolecule modification GO:0043412 111 0.019
anterior posterior pattern specification GO:0009952 152 0.019
synapsis GO:0007129 1 0.019
regulation of protein transport GO:0051223 3 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
taurine metabolic process GO:0019530 1 0.019
axon cargo transport GO:0008088 2 0.019
regionalization GO:0003002 274 0.019
cellular response to extracellular stimulus GO:0031668 2 0.018
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
regulation of erythrocyte differentiation GO:0045646 2 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of developmental growth GO:0048638 38 0.018
l amino acid transport GO:0015807 1 0.018
vesicle localization GO:0051648 27 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of embryonic development GO:0040019 3 0.018
cellular component disassembly GO:0022411 1 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.017
regulation of cellular component size GO:0032535 30 0.017
sphingolipid biosynthetic process GO:0030148 2 0.017
cellular component morphogenesis GO:0032989 336 0.017
response to glucose GO:0009749 3 0.017
transmembrane transport GO:0055085 120 0.017
Human Mouse Rat Worm
negative regulation of catabolic process GO:0009895 3 0.017
positive regulation of catabolic process GO:0009896 4 0.017
autophagy GO:0006914 4 0.016
maintenance of location GO:0051235 4 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
response to organic substance GO:0010033 153 0.016
feeding behavior GO:0007631 5 0.016
Worm
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
sexual reproduction GO:0019953 36 0.016
protein modification process GO:0036211 100 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
developmental growth GO:0048589 166 0.016
cellular ketone metabolic process GO:0042180 11 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
response to radiation GO:0009314 51 0.016
regulation of blood pressure GO:0008217 1 0.016
regulation of gtp catabolic process GO:0033124 2 0.015
embryonic skeletal joint morphogenesis GO:0060272 3 0.015
negative regulation of cell development GO:0010721 26 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of oocyte development GO:0060281 3 0.015
cell morphogenesis GO:0000902 289 0.015
lipid metabolic process GO:0006629 52 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
positive regulation of neurogenesis GO:0050769 24 0.015
growth GO:0040007 174 0.015
carbohydrate homeostasis GO:0033500 1 0.015
endocrine process GO:0050886 2 0.015
amine metabolic process GO:0009308 2 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
urogenital system development GO:0001655 97 0.015
oxoacid metabolic process GO:0043436 31 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of receptor recycling GO:0001919 3 0.014
Rat
cellular localization GO:0051641 97 0.014
negative regulation of cell cycle GO:0045786 14 0.014
larval behavior GO:0030537 5 0.014
phagocytosis GO:0006909 3 0.014
oocyte development GO:0048599 14 0.014
rna biosynthetic process GO:0032774 181 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
centrosome organization GO:0051297 1 0.014
regulation of developmental process GO:0050793 247 0.014
positive regulation of neuron differentiation GO:0045666 12 0.014
positive regulation of signaling GO:0023056 56 0.014
Rat
negative regulation of multicellular organismal process GO:0051241 69 0.014
regulation of cellular component organization GO:0051128 86 0.014
establishment of localization in cell GO:0051649 77 0.014
phosphorus metabolic process GO:0006793 109 0.014
cardiac muscle cell differentiation GO:0055007 30 0.013
cellular component movement GO:0006928 335 0.013
lipid biosynthetic process GO:0008610 22 0.013
positive regulation of neuron projection development GO:0010976 9 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
axonal defasciculation GO:0007414 2 0.013
startle response GO:0001964 4 0.013
adult behavior GO:0030534 2 0.013
regulation of microtubule based movement GO:0060632 3 0.013
response to metal ion GO:0010038 34 0.013
Rat
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
meiotic cell cycle process GO:1903046 3 0.013
exocytosis GO:0006887 1 0.013
cytoplasm organization GO:0007028 4 0.013
single organism reproductive process GO:0044702 40 0.013
gtp metabolic process GO:0046039 4 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
single organism membrane organization GO:0044802 20 0.012
regulation of receptor mediated endocytosis GO:0048259 4 0.012
kidney development GO:0001822 92 0.012
cellular protein modification process GO:0006464 100 0.012
protein localization GO:0008104 40 0.012
Rat
positive regulation of muscle organ development GO:0048636 1 0.012
rna metabolic process GO:0016070 219 0.012
negative regulation of protein kinase b signaling GO:0051898 2 0.012
embryonic skeletal joint development GO:0072498 3 0.012
death GO:0016265 121 0.012
multicellular organismal response to stress GO:0033555 2 0.012
phosphorylation GO:0016310 69 0.012
stem cell maintenance GO:0019827 4 0.012
osteoclast development GO:0036035 1 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
protein phosphorylation GO:0006468 47 0.012
motor neuron axon guidance GO:0008045 23 0.012
homeostatic process GO:0042592 142 0.012
negative regulation of secretion by cell GO:1903531 2 0.011
renal system development GO:0072001 94 0.011
regulation of cell maturation GO:1903429 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
membrane organization GO:0061024 21 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
positive regulation of axonogenesis GO:0050772 6 0.011
developmental maturation GO:0021700 34 0.011
positive regulation of immune system process GO:0002684 17 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
establishment of cell polarity GO:0030010 18 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
multi organism process GO:0051704 134 0.011
regulation of localization GO:0032879 104 0.011
synapse organization GO:0050808 21 0.011
cell migration GO:0016477 237 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
sialylation GO:0097503 4 0.010
positive regulation of ras gtpase activity GO:0032320 1 0.010
regulation of cell activation GO:0050865 1 0.010
heterocycle metabolic process GO:0046483 290 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
female sex differentiation GO:0046660 4 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
single organism membrane fusion GO:0044801 2 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
blood vessel morphogenesis GO:0048514 216 0.010
regulation of cytokine mediated signaling pathway GO:0001959 3 0.010
regulation of extent of cell growth GO:0061387 29 0.010
negative regulation of multi organism process GO:0043901 3 0.010

gria2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.026
congenital nervous system abnormality DOID:2490 0 0.026
disease of metabolism DOID:0014667 0 0.012