Danio rerio

17 known processes

grk1b

G protein-coupled receptor kinase 1 b

(Aliases: zgc:112194)

grk1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phototransduction GO:0007602 2 0.282
Zebrafish
phototransduction visible light GO:0007603 2 0.173
Zebrafish
cilium organization GO:0044782 71 0.135
eye development GO:0001654 277 0.132
apical protein localization GO:0045176 6 0.116
sensory organ development GO:0007423 393 0.115
cellular response to radiation GO:0071478 4 0.113
light absorption GO:0016037 2 0.100
neurological system process GO:0050877 62 0.094
Zebrafish
regulation of guanylate cyclase activity GO:0031282 6 0.084
camera type eye development GO:0043010 222 0.083
smoothened signaling pathway GO:0007224 30 0.082
Zebrafish
signal transduction GO:0007165 455 0.077
Zebrafish
neuron differentiation GO:0030182 353 0.074
chordate embryonic development GO:0043009 271 0.070
Zebrafish
system process GO:0003008 185 0.068
Zebrafish
muscle structure development GO:0061061 196 0.063
Zebrafish
generation of neurons GO:0048699 385 0.062
camera type eye morphogenesis GO:0048593 108 0.061
muscle cell differentiation GO:0042692 139 0.059
Zebrafish
regulation of nucleotide biosynthetic process GO:0030808 15 0.058
sensory perception of light stimulus GO:0050953 19 0.057
Zebrafish
retina development in camera type eye GO:0060041 146 0.053
cilium assembly GO:0042384 58 0.052
regulation of signaling GO:0023051 235 0.051
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.048
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.047
absorption of visible light GO:0016038 2 0.046
aging GO:0007568 2 0.045
purine nucleotide biosynthetic process GO:0006164 20 0.045
regulation of sequestering of calcium ion GO:0051282 4 0.045
eye morphogenesis GO:0048592 144 0.044
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.043
morphogenesis of an epithelium GO:0002009 333 0.042
ribose phosphate biosynthetic process GO:0046390 20 0.041
cellular component assembly involved in morphogenesis GO:0010927 107 0.041
regulation of cell communication GO:0010646 232 0.041
Zebrafish
positive regulation of transport GO:0051050 2 0.040
digestive tract development GO:0048565 265 0.040
cell morphogenesis GO:0000902 289 0.039
detection of stimulus GO:0051606 29 0.039
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.038
single organismal cell cell adhesion GO:0016337 29 0.038
positive regulation of biological process GO:0048518 253 0.038
Zebrafish
brain development GO:0007420 293 0.037
meiotic nuclear division GO:0007126 4 0.037
regulation of response to stimulus GO:0048583 269 0.037
Zebrafish
heterocycle metabolic process GO:0046483 290 0.037
golgi vesicle transport GO:0048193 3 0.036
cellular response to light stimulus GO:0071482 4 0.036
ribonucleotide biosynthetic process GO:0009260 20 0.036
negative regulation of biological process GO:0048519 304 0.035
nitrogen compound metabolic process GO:0006807 319 0.033
sensory perception of chemical stimulus GO:0007606 3 0.033
protein metabolic process GO:0019538 183 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.032
regulation of wnt signaling pathway GO:0030111 53 0.032
Zebrafish
detection of visible light GO:0009584 12 0.032
Zebrafish
sequestering of metal ion GO:0051238 3 0.032
maintenance of location GO:0051235 4 0.031
regulation of biological quality GO:0065008 263 0.030
light induced release of internally sequestered calcium ion GO:0008377 1 0.030
cyclic purine nucleotide metabolic process GO:0052652 18 0.030
neuron development GO:0048666 262 0.030
rhodopsin mediated signaling pathway GO:0016056 1 0.029
multicellular organism growth GO:0035264 4 0.029
establishment of synaptic vesicle localization GO:0097480 1 0.029
cell projection organization GO:0030030 284 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
positive regulation of guanylate cyclase activity GO:0031284 6 0.028
gastrulation GO:0007369 208 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
regulation of neurotransmitter secretion GO:0046928 1 0.028
central nervous system development GO:0007417 387 0.028
medulla oblongata development GO:0021550 4 0.027
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.027
larval development GO:0002164 2 0.027
neurotransmitter secretion GO:0007269 2 0.027
small molecule metabolic process GO:0044281 77 0.027
positive regulation of cgmp biosynthetic process GO:0030828 6 0.027
positive regulation of cellular process GO:0048522 201 0.027
Zebrafish
embryonic heart tube development GO:0035050 133 0.027
multicellular organismal signaling GO:0035637 22 0.026
single organism organelle organization GO:1902589 199 0.026
photoreceptor cell development GO:0042461 40 0.026
regulation of neurotransmitter transport GO:0051588 1 0.026
regulation of cgmp biosynthetic process GO:0030826 6 0.026
regulation of muscle contraction GO:0006937 3 0.025
positive regulation of catabolic process GO:0009896 4 0.025
regulation of inflammatory response GO:0050727 2 0.025
cellular component disassembly GO:0022411 1 0.025
regulation of response to nutrient levels GO:0032107 1 0.025
cell projection morphogenesis GO:0048858 244 0.025
cellular component morphogenesis GO:0032989 336 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
regulation of metabolic process GO:0019222 359 0.025
urogenital system development GO:0001655 97 0.024
visual perception GO:0007601 17 0.024
Zebrafish
photoreceptor cell fate commitment GO:0046552 1 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
response to light stimulus GO:0009416 46 0.023
Zebrafish
cgmp biosynthetic process GO:0006182 7 0.023
negative regulation of cellular process GO:0048523 283 0.022
response to external stimulus GO:0009605 264 0.022
Zebrafish
amine metabolic process GO:0009308 2 0.022
protein modification process GO:0036211 100 0.022
photoreceptor cell differentiation GO:0046530 55 0.022
cellular response to nutrient levels GO:0031669 2 0.021
synaptic vesicle localization GO:0097479 1 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
establishment of localization GO:0051234 244 0.021
head development GO:0060322 303 0.021
meiotic cell cycle process GO:1903046 3 0.021
cellular biosynthetic process GO:0044249 286 0.021
single organism metabolic process GO:0044710 217 0.021
sequestering of calcium ion GO:0051208 3 0.020
photoreceptor cell outer segment organization GO:0035845 9 0.020
phosphorylation GO:0016310 69 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of circadian rhythm GO:0042752 4 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
cellular component biogenesis GO:0044085 178 0.020
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.020
stem cell proliferation GO:0072089 4 0.020
purine containing compound biosynthetic process GO:0072522 20 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
locomotor rhythm GO:0045475 3 0.020
regulation of membrane potential GO:0042391 23 0.020
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.020
tube morphogenesis GO:0035239 349 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
protein localization to plasma membrane GO:0072659 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of reproductive process GO:2000241 4 0.019
cilium morphogenesis GO:0060271 85 0.019
cell part morphogenesis GO:0032990 246 0.019
maintenance of cell polarity GO:0030011 5 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.018
positive regulation of cell cycle GO:0045787 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
sleep GO:0030431 1 0.018
adult behavior GO:0030534 2 0.018
response to drug GO:0042493 3 0.018
biosynthetic process GO:0009058 294 0.018
cell projection assembly GO:0030031 64 0.018
fertilization GO:0009566 3 0.018
gtp catabolic process GO:0006184 2 0.018
single organism localization GO:1902578 225 0.018
synaptic vesicle endocytosis GO:0048488 1 0.018
cellular component assembly GO:0022607 170 0.018
cell adhesion GO:0007155 40 0.018
macromolecule modification GO:0043412 111 0.017
muscle tissue development GO:0060537 110 0.017
regulation of signal transduction GO:0009966 225 0.017
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.017
cyclic nucleotide biosynthetic process GO:0009190 18 0.017
phosphorus metabolic process GO:0006793 109 0.017
organic substance biosynthetic process GO:1901576 289 0.017
wnt signaling pathway GO:0016055 80 0.017
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
glomerulus development GO:0032835 27 0.017
protein complex disassembly GO:0043241 1 0.017
hormone secretion GO:0046879 2 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of hormone secretion GO:0046883 2 0.017
renal system development GO:0072001 94 0.017
negative regulation of protein kinase activity GO:0006469 4 0.016
single organism biosynthetic process GO:0044711 71 0.016
water transport GO:0006833 15 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of cell differentiation GO:0045595 142 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
hormone transport GO:0009914 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
regulation of binding GO:0051098 3 0.016
positive regulation of cell communication GO:0010647 56 0.016
Zebrafish
organic acid metabolic process GO:0006082 31 0.016
calcium mediated signaling GO:0019722 2 0.016
digestive tract morphogenesis GO:0048546 231 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.016
chemosensory behavior GO:0007635 1 0.016
adherens junction organization GO:0034332 4 0.016
ion transport GO:0006811 114 0.016
circadian sleep wake cycle process GO:0022410 2 0.016
vasculature development GO:0001944 278 0.016
actin filament based movement GO:0030048 1 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
neurotransmitter transport GO:0006836 2 0.016
phagocytosis GO:0006909 3 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
gene expression GO:0010467 252 0.016
cardiac muscle tissue development GO:0048738 48 0.015
cellular ketone metabolic process GO:0042180 11 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
cellular component movement GO:0006928 335 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
cell migration GO:0016477 237 0.015
entrainment of circadian clock by photoperiod GO:0043153 1 0.015
regulation of dendrite development GO:0050773 3 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
macromolecular complex disassembly GO:0032984 1 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
homeostatic process GO:0042592 142 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
action potential GO:0001508 19 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
regulation of gene expression GO:0010468 265 0.015
stem cell division GO:0017145 1 0.015
regulation of canonical wnt signaling pathway GO:0060828 34 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
synaptic vesicle transport GO:0048489 1 0.015
cellular response to external stimulus GO:0071496 2 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
response to chemical GO:0042221 320 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
cellular amine metabolic process GO:0044106 2 0.014
regulation of protein complex assembly GO:0043254 3 0.014
neuronal action potential GO:0019228 18 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
response to uv GO:0009411 3 0.014
regulation of circadian sleep wake cycle GO:0042749 1 0.014
embryonic organ development GO:0048568 381 0.014
detection of abiotic stimulus GO:0009582 24 0.014
Zebrafish
regulation of localization GO:0032879 104 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
digestive system development GO:0055123 289 0.014
cellular protein metabolic process GO:0044267 129 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
nephron development GO:0072006 31 0.014
pronephros development GO:0048793 69 0.014
determination of bilateral symmetry GO:0009855 204 0.014
actin mediated cell contraction GO:0070252 1 0.014
g protein coupled receptor signaling pathway GO:0007186 74 0.014
cytokinesis GO:0000910 3 0.014
organelle assembly GO:0070925 110 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
internal protein amino acid acetylation GO:0006475 2 0.013
hindbrain development GO:0030902 91 0.013
ear development GO:0043583 127 0.013
photoreceptor cell morphogenesis GO:0008594 1 0.013
rna metabolic process GO:0016070 219 0.013
negative regulation of signaling GO:0023057 96 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
neuroblast proliferation GO:0007405 2 0.013
organelle organization GO:0006996 227 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
oxoacid metabolic process GO:0043436 31 0.013
striated muscle tissue development GO:0014706 110 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
cognition GO:0050890 1 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
regulation of developmental process GO:0050793 247 0.013
eye photoreceptor cell differentiation GO:0001754 45 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
notch signaling pathway GO:0007219 35 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
small molecule catabolic process GO:0044282 3 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
response to topologically incorrect protein GO:0035966 2 0.012
epithelial cell differentiation GO:0030855 116 0.012
circadian sleep wake cycle GO:0042745 2 0.012
neural tube development GO:0021915 62 0.012
carbohydrate homeostasis GO:0033500 1 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
developmental growth GO:0048589 166 0.012
defense response GO:0006952 47 0.012
negative regulation of kinase activity GO:0033673 4 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of sodium ion transport GO:0002028 2 0.012
regulation of metal ion transport GO:0010959 4 0.012
lens fiber cell development GO:0070307 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
single organism cell adhesion GO:0098602 29 0.012
regulation of lyase activity GO:0051339 12 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
protein depolymerization GO:0051261 1 0.012
negative regulation of wnt signaling pathway GO:0030178 30 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.012
positive regulation of cell division GO:0051781 2 0.012
cyclic nucleotide metabolic process GO:0009187 18 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
response to amphetamine GO:0001975 1 0.012
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.012
exocytosis GO:0006887 1 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
single fertilization GO:0007338 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 17 0.012
muscle organ development GO:0007517 101 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.011
protein secretion GO:0009306 1 0.011
regulation of protein transport GO:0051223 3 0.011
kidney development GO:0001822 92 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
heart morphogenesis GO:0003007 156 0.011
nucleic acid metabolic process GO:0090304 244 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.011
type b pancreatic cell development GO:0003323 4 0.011
endosomal transport GO:0016197 2 0.011
protein acylation GO:0043543 3 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
rna biosynthetic process GO:0032774 181 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
macromolecule localization GO:0033036 54 0.011
positive regulation of reproductive process GO:2000243 2 0.011
nuclear envelope organization GO:0006998 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
heart development GO:0007507 313 0.011
transport GO:0006810 220 0.011
purine ribonucleotide biosynthetic process GO:0009152 20 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
cellular protein complex disassembly GO:0043624 1 0.011
ion transmembrane transport GO:0034220 91 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
response to vitamin GO:0033273 3 0.011
response to food GO:0032094 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
transmission of nerve impulse GO:0019226 19 0.011
regulation of protein binding GO:0043393 3 0.011
cell motility GO:0048870 244 0.011
regulation of tube size GO:0035150 2 0.011
eye photoreceptor cell development GO:0042462 30 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
regulation of cell activation GO:0050865 1 0.011
single organism transport GO:0044765 206 0.011
transmembrane transport GO:0055085 120 0.010
nuclear transport GO:0051169 4 0.010
protein polymerization GO:0051258 4 0.010
rna localization GO:0006403 4 0.010
regulation of dna replication GO:0006275 3 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
glucose homeostasis GO:0042593 1 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
response to hexose GO:0009746 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
hemopoiesis GO:0030097 183 0.010
amino acid transport GO:0006865 2 0.010
response to radiation GO:0009314 51 0.010
Zebrafish
protein phosphorylation GO:0006468 47 0.010
cation transmembrane transport GO:0098655 65 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
protein modification by small protein removal GO:0070646 1 0.010
regulation of blood vessel size GO:0050880 2 0.010
renal filtration GO:0097205 10 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
mitochondrion organization GO:0007005 4 0.010

grk1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.051
disease of anatomical entity DOID:7 0 0.051
eye and adnexa disease DOID:1492 0 0.039
sensory system disease DOID:0050155 0 0.039
eye disease DOID:5614 0 0.039
retinal disease DOID:5679 0 0.019
retinal degeneration DOID:8466 0 0.013