Danio rerio

22 known processes

grma

glutamate receptor, metabotropic a

(Aliases: MGC158329,cb496,zK13A21.16,zgc:158329)

grma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 35 0.234
Rat
neurotransmitter transport GO:0006836 2 0.146
regulation of cell communication GO:0010646 232 0.114
regulation of signaling GO:0023051 235 0.102
regulation of neurotransmitter secretion GO:0046928 1 0.082
regionalization GO:0003002 274 0.076
regulation of neurotransmitter transport GO:0051588 1 0.073
camera type eye development GO:0043010 222 0.073
Mouse
neurotransmitter secretion GO:0007269 2 0.069
regulation of nervous system development GO:0051960 90 0.067
embryonic organ development GO:0048568 381 0.064
cognition GO:0050890 1 0.062
forebrain cell migration GO:0021885 1 0.061
directional locomotion GO:0033058 1 0.059
neuron neuron synaptic transmission GO:0007270 1 0.059
neuron projection morphogenesis GO:0048812 161 0.058
mesenchyme development GO:0060485 127 0.057
single organism localization GO:1902578 225 0.057
regulation of synaptic plasticity GO:0048167 1 0.057
signal transduction GO:0007165 455 0.056
Mouse Rat
stem cell proliferation GO:0072089 4 0.055
organelle organization GO:0006996 227 0.055
neuron differentiation GO:0030182 353 0.055
cell morphogenesis involved in differentiation GO:0000904 195 0.055
transport GO:0006810 220 0.052
organonitrogen compound metabolic process GO:1901564 74 0.052
regulation of synapse organization GO:0050807 3 0.050
regulation of metabolic process GO:0019222 359 0.050
neuroblast proliferation GO:0007405 2 0.048
single organism transport GO:0044765 206 0.045
establishment of localization GO:0051234 244 0.045
single organism metabolic process GO:0044710 217 0.045
Worm
maternal determination of anterior posterior axis embryo GO:0008358 4 0.045
eye development GO:0001654 277 0.044
Mouse
larval development GO:0002164 2 0.043
localization of cell GO:0051674 244 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.043
cortical actin cytoskeleton organization GO:0030866 1 0.042
locomotion GO:0040011 313 0.042
apical junction assembly GO:0043297 1 0.041
positive regulation of transport GO:0051050 2 0.040
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.039
generation of neurons GO:0048699 385 0.039
regulation of synapse assembly GO:0051963 3 0.039
regulation of neuronal synaptic plasticity GO:0048168 1 0.037
oocyte anterior posterior axis specification GO:0007314 4 0.036
adherens junction organization GO:0034332 4 0.036
regulation of primary metabolic process GO:0080090 311 0.035
regulation of neurogenesis GO:0050767 87 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.035
response to drug GO:0042493 3 0.035
regulation of cellular metabolic process GO:0031323 320 0.034
sensory organ morphogenesis GO:0090596 200 0.034
morphogenesis of an epithelium GO:0002009 333 0.034
phosphate containing compound metabolic process GO:0006796 108 0.034
mesenchymal cell differentiation GO:0048762 87 0.034
response to light stimulus GO:0009416 46 0.034
embryonic organ morphogenesis GO:0048562 274 0.033
heterocycle metabolic process GO:0046483 290 0.032
regulation of purine nucleotide catabolic process GO:0033121 2 0.032
response to chemical GO:0042221 320 0.031
positive regulation of biological process GO:0048518 253 0.031
Worm
cortical cytoskeleton organization GO:0030865 1 0.031
neural crest cell development GO:0014032 62 0.031
regulation of synaptic transmission GO:0050804 4 0.031
cellular component morphogenesis GO:0032989 336 0.031
system process GO:0003008 185 0.031
axonogenesis GO:0007409 152 0.030
positive regulation of catabolic process GO:0009896 4 0.030
developmental cell growth GO:0048588 52 0.030
pole plasm assembly GO:0007315 4 0.030
positive regulation of cell cycle GO:0045787 3 0.030
cellular component assembly GO:0022607 170 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
regulation of cell development GO:0060284 100 0.029
intracellular mrna localization GO:0008298 1 0.028
cgmp metabolic process GO:0046068 7 0.027
behavior GO:0007610 74 0.027
Mouse
rna localization GO:0006403 4 0.027
gtp metabolic process GO:0046039 4 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.027
gland development GO:0048732 143 0.026
cell migration GO:0016477 237 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
axon development GO:0061564 166 0.026
digestive tract morphogenesis GO:0048546 231 0.026
cell cell signaling GO:0007267 52 0.026
Rat
positive regulation of cgmp biosynthetic process GO:0030828 6 0.025
response to hexose GO:0009746 3 0.025
growth GO:0040007 174 0.025
protein polymerization GO:0051258 4 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
cell morphogenesis GO:0000902 289 0.025
cell part morphogenesis GO:0032990 246 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of reproductive process GO:2000241 4 0.025
gtp catabolic process GO:0006184 2 0.024
determination of left right symmetry GO:0007368 179 0.024
cell projection morphogenesis GO:0048858 244 0.024
cytoplasm organization GO:0007028 4 0.024
sensory perception of chemical stimulus GO:0007606 3 0.024
phagocytosis GO:0006909 3 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
response to monosaccharide GO:0034284 3 0.024
regulation of axonogenesis GO:0050770 32 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
autophagy GO:0006914 4 0.023
determination of bilateral symmetry GO:0009855 204 0.023
positive regulation of synapse assembly GO:0051965 1 0.023
negative regulation of signaling GO:0023057 96 0.023
regulation of protein polymerization GO:0032271 2 0.023
embryonic heart tube morphogenesis GO:0003143 108 0.022
synaptic vesicle localization GO:0097479 1 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
response to glucocorticoid GO:0051384 1 0.022
heart development GO:0007507 313 0.022
immune system process GO:0002376 241 0.021
single organism cellular localization GO:1902580 46 0.021
stem cell development GO:0048864 82 0.021
negative regulation of cell communication GO:0010648 96 0.021
meiotic nuclear division GO:0007126 4 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.020
tube morphogenesis GO:0035239 349 0.020
protein targeting to membrane GO:0006612 1 0.020
response to carbohydrate GO:0009743 3 0.020
heart morphogenesis GO:0003007 156 0.020
regulation of biological quality GO:0065008 263 0.020
Worm
retina layer formation GO:0010842 24 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
cellular component biogenesis GO:0044085 178 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
forebrain development GO:0030900 96 0.019
response to glucose GO:0009749 3 0.019
neuron development GO:0048666 262 0.019
protein localization to plasma membrane GO:0072659 1 0.019
fertilization GO:0009566 3 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
pancreas development GO:0031016 84 0.019
cellular response to radiation GO:0071478 4 0.019
neuron projection development GO:0031175 180 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
positive regulation of cellular process GO:0048522 201 0.018
synaptic vesicle transport GO:0048489 1 0.018
skeletal system development GO:0001501 181 0.018
digestive tract development GO:0048565 265 0.018
cellular amine metabolic process GO:0044106 2 0.018
lateral inhibition GO:0046331 1 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
response to food GO:0032094 1 0.018
response to stress GO:0006950 263 0.018
developmental growth GO:0048589 166 0.018
gastrulation GO:0007369 208 0.017
centrosome localization GO:0051642 1 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
single organism organelle organization GO:1902589 199 0.017
negative regulation of cellular process GO:0048523 283 0.017
regulation of protein transport GO:0051223 3 0.017
response to corticosteroid GO:0031960 1 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
sensory perception GO:0007600 39 0.017
regulation of cytoplasmic transport GO:1903649 4 0.016
polarized epithelial cell differentiation GO:0030859 4 0.016
sympathetic nervous system development GO:0048485 3 0.016
olfactory bulb development GO:0021772 4 0.016
regulation of cgmp metabolic process GO:0030823 6 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
vesicle localization GO:0051648 27 0.016
regulation of inflammatory response GO:0050727 2 0.016
regulation of neuron differentiation GO:0045664 56 0.015
regulation of neurological system process GO:0031644 2 0.015
glial cell migration GO:0008347 3 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
skeletal system morphogenesis GO:0048705 102 0.015
neuromuscular process controlling balance GO:0050885 3 0.015
ameboidal type cell migration GO:0001667 143 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
specification of symmetry GO:0009799 204 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
establishment of vesicle localization GO:0051650 24 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cell projection organization GO:0030030 284 0.014
retina development in camera type eye GO:0060041 146 0.014
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.014
small molecule catabolic process GO:0044282 3 0.014
negative regulation of biological process GO:0048519 304 0.014
cellular component maintenance GO:0043954 3 0.014
female sex differentiation GO:0046660 4 0.014
camera type eye morphogenesis GO:0048593 108 0.014
regulation of dna replication GO:0006275 3 0.014
cell death GO:0008219 121 0.014
cellular component movement GO:0006928 335 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
regulation of cell differentiation GO:0045595 142 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
Rat
meiotic cell cycle process GO:1903046 3 0.014
regulation of cgmp biosynthetic process GO:0030826 6 0.014
response to alkaloid GO:0043279 2 0.014
regulation of apoptotic process GO:0042981 98 0.013
establishment of epithelial cell polarity GO:0090162 2 0.013
stem cell differentiation GO:0048863 117 0.013
negative regulation of signal transduction GO:0009968 94 0.013
blood circulation GO:0008015 87 0.013
neural tube development GO:0021915 62 0.013
regulation of neuron migration GO:2001222 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
photoreceptor cell differentiation GO:0046530 55 0.013
multicellular organismal signaling GO:0035637 22 0.013
mesenchymal cell development GO:0014031 78 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
cellular macromolecule metabolic process GO:0044260 391 0.013
small molecule metabolic process GO:0044281 77 0.013
positive regulation of neurogenesis GO:0050769 24 0.013
exocytosis GO:0006887 1 0.013
neurological system process GO:0050877 62 0.013
vasculature development GO:0001944 278 0.013
mesoderm development GO:0007498 88 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
regulation of response to stimulus GO:0048583 269 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
segmentation GO:0035282 97 0.013
outflow tract morphogenesis GO:0003151 1 0.013
stem cell maintenance GO:0019827 4 0.012
cell junction maintenance GO:0034331 2 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
positive regulation of secretion GO:0051047 1 0.012
regulation of protein complex assembly GO:0043254 3 0.012
protein complex disassembly GO:0043241 1 0.012
central nervous system neuron development GO:0021954 29 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
olfactory lobe development GO:0021988 4 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
response to ketone GO:1901654 1 0.012
sleep GO:0030431 1 0.012
programmed cell death GO:0012501 119 0.012
regulation of molecular function GO:0065009 70 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
organic substance biosynthetic process GO:1901576 289 0.012
nerve development GO:0021675 45 0.012
single fertilization GO:0007338 3 0.012
regulation of binding GO:0051098 3 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
chordate embryonic development GO:0043009 271 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
apoptotic process GO:0006915 116 0.012
cellular response to light stimulus GO:0071482 4 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
response to nutrient GO:0007584 3 0.011
cytoskeleton organization GO:0007010 96 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of dendrite development GO:0050773 3 0.011
blood vessel morphogenesis GO:0048514 216 0.011
chemosensory behavior GO:0007635 1 0.011
actin filament polymerization GO:0030041 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
angiogenesis GO:0001525 158 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of cell projection assembly GO:0060491 4 0.011
aging GO:0007568 2 0.011
regulation of neuron projection development GO:0010975 40 0.011
regulation of catalytic activity GO:0050790 55 0.011
cranial nerve development GO:0021545 42 0.011
death GO:0016265 121 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of developmental growth GO:0048638 38 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
axonal defasciculation GO:0007414 2 0.010
taxis GO:0042330 109 0.010
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.010
embryonic eye morphogenesis GO:0048048 30 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
regulation of developmental process GO:0050793 247 0.010
digestive tract mesoderm development GO:0007502 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
lens fiber cell development GO:0070307 3 0.010
positive regulation of cgmp metabolic process GO:0030825 6 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
locomotory behavior GO:0007626 34 0.010
Mouse
embryonic skeletal system development GO:0048706 97 0.010
locomotor rhythm GO:0045475 3 0.010
regulation of biosynthetic process GO:0009889 250 0.010
regulation of tube size GO:0035150 2 0.010

grma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015