|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.904
|
Worm |
|
|
nuclear migration
|
GO:0007097 |
3 |
0.827
|
Worm |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.813
|
Rat Fly |
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.806
|
Worm |
|
|
larval development
|
GO:0002164 |
2 |
0.794
|
Worm |
|
|
signal transduction
|
GO:0007165 |
455 |
0.766
|
Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.739
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.709
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.705
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.669
|
Fly |
|
|
response to chemical
|
GO:0042221 |
320 |
0.656
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
71 |
0.654
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.648
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.648
|
Worm Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.642
|
Worm Fly |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.635
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.619
|
Worm Fly |
|
|
optic placode formation
|
GO:0001743 |
4 |
0.594
|
|
|
|
germ line stem cell division
|
GO:0042078 |
1 |
0.582
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.567
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.531
|
|
|
|
chromosome organization
|
GO:0051276 |
31 |
0.528
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.526
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.525
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.494
|
Worm Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.492
|
|
|
|
pronuclear migration
|
GO:0035046 |
1 |
0.491
|
Worm |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.482
|
Rat Fly |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.478
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.477
|
Worm Fly |
|
|
vasculature development
|
GO:0001944 |
278 |
0.476
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.473
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.470
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.470
|
Worm Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.467
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.464
|
|
|
|
negative regulation of neuron projection regeneration
|
GO:0070571 |
4 |
0.452
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.438
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.414
|
Rat Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.408
|
Rat Fly |
|
|
regulation of response to nutrient levels
|
GO:0032107 |
1 |
0.407
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.405
|
Rat Fly |
|
|
blood vessel development
|
GO:0001568 |
246 |
0.400
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.396
|
Worm |
|
|
central nervous system development
|
GO:0007417 |
387 |
0.395
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.394
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.389
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.388
|
Worm Fly |
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.387
|
Worm |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.385
|
|
|
|
heart jogging
|
GO:0003146 |
40 |
0.381
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.380
|
Rat Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.371
|
|
|
|
negative regulation of collateral sprouting
|
GO:0048671 |
2 |
0.370
|
|
|
|
eye field cell fate commitment involved in camera type eye formation
|
GO:0060898 |
3 |
0.365
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
53 |
0.361
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.359
|
Fly |
|
|
cilium assembly
|
GO:0042384 |
58 |
0.359
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
2 |
0.350
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.341
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.339
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.334
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.334
|
|
|
|
fertilization
|
GO:0009566 |
3 |
0.329
|
Worm |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.323
|
Rat Fly |
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.320
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.312
|
|
|
|
endoderm formation
|
GO:0001706 |
29 |
0.307
|
|
|
|
head development
|
GO:0060322 |
303 |
0.303
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.303
|
Worm |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.302
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.298
|
Worm |
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.297
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.291
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.286
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.282
|
Zebrafish |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.281
|
Fly |
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.281
|
Worm |
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.278
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.275
|
Worm Fly |
|
|
single fertilization
|
GO:0007338 |
3 |
0.275
|
Worm |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.273
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.272
|
|
|
|
positive regulation of oocyte development
|
GO:0060282 |
1 |
0.272
|
|
|
|
periodic partitioning
|
GO:0007365 |
1 |
0.271
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.268
|
Worm |
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.266
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.264
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.263
|
Rat Fly |
|
|
cell projection organization
|
GO:0030030 |
284 |
0.262
|
Worm Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.262
|
Worm |
|
|
segment polarity determination
|
GO:0007367 |
1 |
0.259
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.259
|
Fly |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.257
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.256
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.248
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.248
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.246
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.243
|
Rat Fly |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.242
|
Rat Fly |
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.240
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.238
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.236
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
6 |
0.233
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.231
|
Rat Fly |
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.230
|
Rat Fly |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.224
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
180 |
0.223
|
Worm Fly |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.221
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
74 |
0.220
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.219
|
Worm |
|
|
organelle organization
|
GO:0006996 |
227 |
0.219
|
Fly |
|
|
macroautophagy
|
GO:0016236 |
1 |
0.217
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.212
|
Worm Fly |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.210
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.210
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.209
|
Worm |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.207
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.206
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.204
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
7 |
0.202
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.198
|
Zebrafish |
|
|
notch signaling pathway
|
GO:0007219 |
35 |
0.197
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.196
|
Fly |
|
|
developmental growth
|
GO:0048589 |
166 |
0.194
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.190
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
7 |
0.188
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
11 |
0.187
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.187
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.182
|
Rat Fly |
|
|
heart development
|
GO:0007507 |
313 |
0.182
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.182
|
Rat Fly |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.181
|
|
|
|
regulation of bmp signaling pathway involved in heart jogging
|
GO:2000223 |
12 |
0.179
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.177
|
Fly |
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.177
|
Fly |
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
20 |
0.177
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.175
|
Worm |
|
|
single organism transport
|
GO:0044765 |
206 |
0.175
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.174
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.174
|
|
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
1 |
0.173
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.173
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
1 |
0.173
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.172
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.172
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.172
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.172
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
1 |
0.171
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.170
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.168
|
Rat Fly |
|
|
cell cycle process
|
GO:0022402 |
53 |
0.166
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.164
|
Worm |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.164
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.164
|
Worm |
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.163
|
Rat Fly |
|
|
mesoderm morphogenesis
|
GO:0048332 |
51 |
0.162
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.162
|
Worm |
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.160
|
|
|
|
response to growth factor
|
GO:0070848 |
39 |
0.160
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.159
|
Worm |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.158
|
|
|
|
oocyte maturation
|
GO:0001556 |
4 |
0.158
|
|
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.158
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.157
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.157
|
Rat Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
52 |
0.157
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
1 |
0.156
|
|
|
|
organelle localization
|
GO:0051640 |
49 |
0.155
|
Worm |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.155
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.154
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.154
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
29 |
0.152
|
|
|
|
aging
|
GO:0007568 |
2 |
0.151
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.147
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.146
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.146
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.145
|
Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.145
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
3 |
0.145
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.145
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.145
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
6 |
0.144
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.144
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
11 |
0.144
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.144
|
|
|
|
optic placode formation involved in camera type eye formation
|
GO:0046619 |
3 |
0.144
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.144
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.142
|
|
|
|
negative regulation of collateral sprouting of intact axon in response to injury
|
GO:0048685 |
2 |
0.142
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.141
|
|
|
|
regulation of cell size
|
GO:0008361 |
29 |
0.141
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.138
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.138
|
|
|
|
regulation of retinoic acid biosynthetic process
|
GO:1900052 |
6 |
0.137
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.137
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.137
|
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.137
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
20 |
0.137
|
|
|
|
regulation of axon extension
|
GO:0030516 |
24 |
0.137
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.136
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.136
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.135
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.134
|
Zebrafish |
|
|
stem cell division
|
GO:0017145 |
1 |
0.134
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.134
|
Worm Fly |
|
|
wound healing
|
GO:0042060 |
90 |
0.133
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.131
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.131
|
Fly |
|
|
negative regulation of axon regeneration
|
GO:0048681 |
4 |
0.130
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.130
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.129
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
6 |
0.129
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.129
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.128
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
4 |
0.127
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.126
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.125
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.124
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.122
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
3 |
0.122
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.122
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.122
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.122
|
|
|
|
nucleus localization
|
GO:0051647 |
8 |
0.121
|
Worm |
|
|
hindbrain development
|
GO:0030902 |
91 |
0.121
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.120
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
32 |
0.120
|
Worm |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.119
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.119
|
|
|
|
somatic muscle development
|
GO:0007525 |
4 |
0.118
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
3 |
0.117
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.113
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.113
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.113
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.112
|
Fly |
|
|
apoptotic process
|
GO:0006915 |
116 |
0.112
|
|
|
|
gene silencing by rna
|
GO:0031047 |
4 |
0.111
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
6 |
0.110
|
Fly |
|
|
negative regulation of autophagy
|
GO:0010507 |
1 |
0.110
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.110
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.108
|
Worm |
|
|
germ cell development
|
GO:0007281 |
22 |
0.108
|
Worm |
|
|
response to wounding
|
GO:0009611 |
116 |
0.107
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.106
|
Fly |
|
|
dorsal convergence
|
GO:0060030 |
14 |
0.105
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
18 |
0.105
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.104
|
Worm |
|
|
negative chemotaxis
|
GO:0050919 |
1 |
0.104
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.104
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.104
|
Worm |
|
|
sensory organ development
|
GO:0007423 |
393 |
0.103
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.102
|
Rat Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.101
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.101
|
Rat Fly |
|
|
proteolysis
|
GO:0006508 |
38 |
0.101
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.101
|
|
|
|
diterpenoid biosynthetic process
|
GO:0016102 |
7 |
0.100
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
2 |
0.100
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
44 |
0.099
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.099
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.099
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.099
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.098
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
11 |
0.097
|
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
2 |
0.097
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.097
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.096
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.096
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
1 |
0.095
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.095
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.095
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.094
|
Rat Fly |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.094
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.093
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.093
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.092
|
Rat Fly |
|
|
mesoderm development
|
GO:0007498 |
88 |
0.092
|
|
|
|
retinoic acid metabolic process
|
GO:0042573 |
9 |
0.091
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
17 |
0.091
|
|
|
|
diencephalon development
|
GO:0021536 |
58 |
0.091
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.090
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.090
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.090
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.090
|
Fly |
|
|
positive regulation of muscle tissue development
|
GO:1901863 |
1 |
0.089
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.088
|
Worm |
|
|
stem cell development
|
GO:0048864 |
82 |
0.088
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.088
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.087
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
12 |
0.087
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
20 |
0.087
|
|
|
|
catabolic process
|
GO:0009056 |
32 |
0.086
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.086
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.086
|
Rat Fly |
|
|
taxis
|
GO:0042330 |
109 |
0.086
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.085
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.084
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.084
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.083
|
Worm |
|
|
establishment of spindle orientation
|
GO:0051294 |
10 |
0.083
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.083
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.083
|
Rat Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.083
|
Fly |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.083
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
7 |
0.082
|
|
|
|
oocyte differentiation
|
GO:0009994 |
14 |
0.082
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.081
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.081
|
|
|
|
autophagy
|
GO:0006914 |
4 |
0.080
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.080
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.079
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.078
|
|
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.078
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.077
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.077
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.076
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.076
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.076
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.075
|
Rat Fly |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.075
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.075
|
|
|
|
developmental cell growth
|
GO:0048588 |
52 |
0.074
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.074
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.074
|
Fly |
|
|
dendrite morphogenesis
|
GO:0048813 |
5 |
0.074
|
Fly |
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.074
|
|
|
|
metencephalon development
|
GO:0022037 |
27 |
0.074
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.073
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.073
|
Worm |
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.073
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.073
|
|
|
|
angioblast cell migration involved in selective angioblast sprouting
|
GO:0035475 |
4 |
0.072
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
3 |
0.072
|
|
|
|
organelle fusion
|
GO:0048284 |
3 |
0.072
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.071
|
Rat Fly |
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
2 |
0.071
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.071
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
19 |
0.071
|
|
|
|
regulation of cell proliferation involved in heart morphogenesis
|
GO:2000136 |
2 |
0.070
|
|
|
|
oocyte development
|
GO:0048599 |
14 |
0.070
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
27 |
0.070
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.070
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.069
|
|
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.069
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.069
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.068
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.068
|
|
|
|
ectodermal placode development
|
GO:0071696 |
37 |
0.068
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.067
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.067
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.067
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.067
|
Zebrafish |
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.067
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.067
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
29 |
0.066
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.066
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
1 |
0.066
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.066
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.066
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
45 |
0.066
|
Worm |
|
|
growth
|
GO:0040007 |
174 |
0.065
|
|
|
|
spinal cord radial glial cell differentiation
|
GO:0021531 |
2 |
0.065
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.065
|
Worm |
|
|
axon extension
|
GO:0048675 |
45 |
0.065
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
5 |
0.065
|
Worm |
|
|
regulation of developmental growth
|
GO:0048638 |
38 |
0.064
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.064
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.064
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.064
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.064
|
Fly |
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.064
|
Worm |
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
3 |
0.064
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.064
|
Worm |
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
18 |
0.063
|
Fly |
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
3 |
0.063
|
|
|
|
organelle transport along microtubule
|
GO:0072384 |
1 |
0.063
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.063
|
|
|
|
artery development
|
GO:0060840 |
22 |
0.062
|
|
|
|
fin regeneration
|
GO:0031101 |
51 |
0.062
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.062
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.061
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.061
|
Fly |
|
|
negative regulation of neuron projection development
|
GO:0010977 |
9 |
0.061
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.061
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.061
|
Worm |
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
15 |
0.061
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.061
|
Fly |
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.060
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.059
|
|
|
|
pronephros development
|
GO:0048793 |
69 |
0.059
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
2 |
0.059
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
29 |
0.058
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.058
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.058
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.058
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.056
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.056
|
Fly |
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
32 |
0.056
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.056
|
Rat Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.055
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.055
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.055
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.055
|
|
|
|
reciprocal dna recombination
|
GO:0035825 |
1 |
0.055
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.055
|
|
|
|
chromatin modification
|
GO:0016568 |
21 |
0.054
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
1 |
0.054
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
14 |
0.054
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.054
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.053
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.053
|
|
|
|
immune response
|
GO:0006955 |
28 |
0.053
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
29 |
0.053
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.053
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.053
|
|
|
|
specification of organ identity
|
GO:0010092 |
2 |
0.052
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.052
|
|
|
|
heart field specification
|
GO:0003128 |
1 |
0.051
|
|
|
|
forebrain regionalization
|
GO:0021871 |
4 |
0.051
|
|
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.051
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
4 |
0.051
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.051
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.051
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.051
|
|
|
|
death
|
GO:0016265 |
121 |
0.050
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.050
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.050
|
|
|
|
protein secretion
|
GO:0009306 |
1 |
0.049
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.049
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
1 |
0.048
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.048
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
6 |
0.048
|
|
|
|
biological adhesion
|
GO:0022610 |
40 |
0.048
|
|
|
|
developmental maturation
|
GO:0021700 |
34 |
0.048
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.047
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
11 |
0.047
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.047
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
34 |
0.047
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.046
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.046
|
|
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
1 |
0.046
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
12 |
0.046
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
22 |
0.046
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.046
|
|
|
|
post anal tail morphogenesis
|
GO:0036342 |
19 |
0.046
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
44 |
0.045
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.045
|
Rat Fly |
|
|
developmental pigmentation
|
GO:0048066 |
48 |
0.045
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.045
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
55 |
0.045
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.045
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.045
|
|
|
|
b cell differentiation
|
GO:0030183 |
1 |
0.044
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.044
|
Worm |
|
|
radial glial cell differentiation
|
GO:0060019 |
2 |
0.043
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.043
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.043
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.042
|
Fly |
|
|
neuron projection extension
|
GO:1990138 |
45 |
0.042
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
30 |
0.042
|
|
|
|
determination of left right asymmetry in nervous system
|
GO:0035545 |
4 |
0.042
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.041
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
2 |
0.041
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
2 |
0.041
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.041
|
Fly |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.041
|
Fly |
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.041
|
Worm |
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.041
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
1 |
0.041
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.041
|
Worm |
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.041
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.041
|
Zebrafish |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.040
|
Rat Fly |
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.040
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.040
|
|
|
|
histone modification
|
GO:0016570 |
20 |
0.040
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.040
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
33 |
0.040
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.039
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
2 |
0.039
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
10 |
0.039
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.039
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
14 |
0.039
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
3 |
0.039
|
|
|
|
regulation of collateral sprouting of intact axon in response to injury
|
GO:0048683 |
2 |
0.038
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.038
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.038
|
Fly |
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
3 |
0.038
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.038
|
|
|
|
female gamete generation
|
GO:0007292 |
14 |
0.038
|
Worm |
|
|
negative regulation of reproductive process
|
GO:2000242 |
3 |
0.038
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.038
|
|
|
|
olfactory lobe development
|
GO:0021988 |
4 |
0.038
|
|
|
|
determination of left right asymmetry in diencephalon
|
GO:0035462 |
4 |
0.038
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.037
|
|
|
|
protein alkylation
|
GO:0008213 |
13 |
0.037
|
|
