Danio rerio

0 known processes

gtf2a1

general transcription factor IIA, 1

(Aliases: fj36b10,zgc:55847,tf2a,wu:fj36b10,wu:fc15h02,fc15h02)

gtf2a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transport GO:0051169 4 0.205
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.195
organic cyclic compound metabolic process GO:1901360 301 0.185
cellular macromolecule metabolic process GO:0044260 391 0.113
regulation of metabolic process GO:0019222 359 0.107
nucleic acid metabolic process GO:0090304 244 0.099
negative regulation of cellular process GO:0048523 283 0.083
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.082
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.082
cellular nitrogen compound metabolic process GO:0034641 290 0.081
regulation of macromolecule metabolic process GO:0060255 317 0.079
cell migration GO:0016477 237 0.077
cellular aromatic compound metabolic process GO:0006725 295 0.075
regulation of protein localization to nucleus GO:1900180 2 0.074
heterocycle metabolic process GO:0046483 290 0.074
single organism organelle organization GO:1902589 199 0.074
hemopoiesis GO:0030097 183 0.071
adult behavior GO:0030534 2 0.070
nucleocytoplasmic transport GO:0006913 4 0.070
regulation of primary metabolic process GO:0080090 311 0.062
regulation of biosynthetic process GO:0009889 250 0.062
cellular protein metabolic process GO:0044267 129 0.061
positive regulation of neutrophil extravasation GO:2000391 1 0.059
regulation of nitrogen compound metabolic process GO:0051171 251 0.058
organic substance biosynthetic process GO:1901576 289 0.058
regulation of cell shape GO:0008360 1 0.058
regulation of gene expression epigenetic GO:0040029 11 0.057
neutrophil mediated immunity GO:0002446 1 0.057
biosynthetic process GO:0009058 294 0.056
negative regulation of ras protein signal transduction GO:0046580 1 0.056
response to chemical GO:0042221 320 0.053
regulation of biological quality GO:0065008 263 0.053
cellular biosynthetic process GO:0044249 286 0.053
regulation of gene expression GO:0010468 265 0.051
hematopoietic or lymphoid organ development GO:0048534 191 0.051
establishment of protein localization to organelle GO:0072594 4 0.051
cell motility GO:0048870 244 0.049
positive regulation of cellular component biogenesis GO:0044089 3 0.049
protein modification process GO:0036211 100 0.048
regulation of cellular metabolic process GO:0031323 320 0.048
regulation of macromolecule biosynthetic process GO:0010556 225 0.047
regulation of rna metabolic process GO:0051252 224 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.047
translational initiation GO:0006413 3 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
regulation of protein ubiquitination GO:0031396 3 0.046
homeostatic process GO:0042592 142 0.046
single organism metabolic process GO:0044710 217 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.045
modification dependent protein catabolic process GO:0019941 3 0.045
positive regulation of cellular process GO:0048522 201 0.045
localization of cell GO:0051674 244 0.044
regulation of establishment of protein localization GO:0070201 4 0.044
macromolecular complex subunit organization GO:0043933 74 0.044
cellular ketone metabolic process GO:0042180 11 0.043
positive regulation of transport GO:0051050 2 0.043
digestive tract morphogenesis GO:0048546 231 0.042
signal transduction GO:0007165 455 0.042
mrna metabolic process GO:0016071 20 0.041
small molecule metabolic process GO:0044281 77 0.041
gene expression GO:0010467 252 0.041
positive regulation of biological process GO:0048518 253 0.040
larval development GO:0002164 2 0.040
nitrogen compound metabolic process GO:0006807 319 0.039
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.039
cellular component morphogenesis GO:0032989 336 0.038
oxoacid metabolic process GO:0043436 31 0.038
regulation of mrna processing GO:0050684 3 0.038
response to stress GO:0006950 263 0.037
positive regulation of macromolecule metabolic process GO:0010604 93 0.037
negative regulation of biological process GO:0048519 304 0.037
organelle organization GO:0006996 227 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
rna metabolic process GO:0016070 219 0.036
g1 s transition of mitotic cell cycle GO:0000082 1 0.036
skeletal system morphogenesis GO:0048705 102 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.036
rna 3 end processing GO:0031123 2 0.036
proteasomal protein catabolic process GO:0010498 2 0.036
cellular extravasation GO:0045123 1 0.035
cellular component movement GO:0006928 335 0.035
cellular protein catabolic process GO:0044257 4 0.035
regulation of nucleocytoplasmic transport GO:0046822 2 0.035
protein polyubiquitination GO:0000209 4 0.035
cognition GO:0050890 1 0.034
maintenance of location GO:0051235 4 0.034
gastrulation GO:0007369 208 0.034
intracellular signal transduction GO:0035556 85 0.033
positive regulation of metabolic process GO:0009893 108 0.033
regulation of cell projection assembly GO:0060491 4 0.032
mitotic cell cycle GO:0000278 64 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
regulation of developmental process GO:0050793 247 0.031
multicellular organism growth GO:0035264 4 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
cell cycle g1 s phase transition GO:0044843 1 0.030
protein import into nucleus GO:0006606 3 0.030
protein metabolic process GO:0019538 183 0.029
immune system process GO:0002376 241 0.029
cellular amine metabolic process GO:0044106 2 0.029
mitotic dna damage checkpoint GO:0044773 4 0.029
negative regulation of nuclear division GO:0051784 3 0.029
mitotic cell cycle process GO:1903047 48 0.028
regulation of neutrophil extravasation GO:2000389 1 0.028
regulation of epithelial cell proliferation GO:0050678 3 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
homeostasis of number of cells GO:0048872 62 0.028
regulation of protein targeting GO:1903533 2 0.028
regulation of binding GO:0051098 3 0.028
regulation of signaling GO:0023051 235 0.028
positive regulation of cellular extravasation GO:0002693 1 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
actin filament based process GO:0030029 64 0.027
mitotic cell cycle embryonic GO:0045448 2 0.027
blood vessel development GO:0001568 246 0.027
organic acid metabolic process GO:0006082 31 0.027
cellular protein modification process GO:0006464 100 0.027
tube morphogenesis GO:0035239 349 0.027
protein import GO:0017038 3 0.026
single organism nuclear import GO:1902593 3 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
aging GO:0007568 2 0.025
regulation of translational initiation GO:0006446 1 0.025
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
transcription dna templated GO:0006351 181 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
myeloid cell differentiation GO:0030099 86 0.024
organism emergence from protective structure GO:0071684 4 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
chemosensory behavior GO:0007635 1 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
cortical actin cytoskeleton organization GO:0030866 1 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
gene silencing GO:0016458 4 0.023
regulation of protein transport GO:0051223 3 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
erythrocyte differentiation GO:0030218 54 0.022
spermatid differentiation GO:0048515 2 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
positive regulation of secretion GO:0051047 1 0.022
death GO:0016265 121 0.022
positive regulation of cell cycle GO:0045787 3 0.022
leukocyte proliferation GO:0070661 1 0.022
regulation of meiotic cell cycle GO:0051445 1 0.021
embryonic limb morphogenesis GO:0030326 2 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
positive regulation of muscle cell differentiation GO:0051149 1 0.021
angiogenesis GO:0001525 158 0.021
nucleic acid templated transcription GO:0097659 181 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
protein complex localization GO:0031503 1 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
membrane fusion GO:0061025 2 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
protein localization to nucleus GO:0034504 3 0.021
erythrocyte homeostasis GO:0034101 55 0.021
cellular component biogenesis GO:0044085 178 0.020
immune system development GO:0002520 191 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
protein polymerization GO:0051258 4 0.020
embryonic organ development GO:0048568 381 0.020
amine metabolic process GO:0009308 2 0.020
alternative mrna splicing via spliceosome GO:0000380 1 0.020
cell part morphogenesis GO:0032990 246 0.020
positive regulation of neutrophil migration GO:1902624 0 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.019
muscle organ development GO:0007517 101 0.019
cell morphogenesis GO:0000902 289 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
b cell activation GO:0042113 2 0.019
stem cell maintenance GO:0019827 4 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of dna templated transcription elongation GO:0032784 3 0.019
regulation of circadian rhythm GO:0042752 4 0.019
positive regulation of catabolic process GO:0009896 4 0.018
peptidyl serine modification GO:0018209 2 0.018
regulation of synapse assembly GO:0051963 3 0.018
negative regulation of chromosome organization GO:2001251 1 0.018
regulation of synapse organization GO:0050807 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
regulation of cell activation GO:0050865 1 0.018
mitochondrial transport GO:0006839 2 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of transcription dna templated GO:0006355 213 0.018
mrna 3 end processing GO:0031124 2 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
ras protein signal transduction GO:0007265 7 0.018
positive regulation of leukocyte differentiation GO:1902107 1 0.018
cellular hormone metabolic process GO:0034754 19 0.018
neutrophil extravasation GO:0072672 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of cell differentiation GO:0045595 142 0.017
rna biosynthetic process GO:0032774 181 0.017
locomotion GO:0040011 313 0.017
cellular component assembly GO:0022607 170 0.017
taxis GO:0042330 109 0.017
cell proliferation GO:0008283 80 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
negative regulation of translation GO:0017148 1 0.017
synaptic vesicle localization GO:0097479 1 0.017
regulation of protein metabolic process GO:0051246 56 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.017
heart development GO:0007507 313 0.017
neuroblast proliferation GO:0007405 2 0.017
regulation of cellular extravasation GO:0002691 1 0.017
cell projection morphogenesis GO:0048858 244 0.017
actin cytoskeleton organization GO:0030036 63 0.016
g2 dna damage checkpoint GO:0031572 3 0.016
positive regulation of cell activation GO:0050867 1 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
response to monosaccharide GO:0034284 3 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
digestive system development GO:0055123 289 0.016
regulation of establishment of planar polarity GO:0090175 4 0.016
response to uv GO:0009411 3 0.016
axonogenesis GO:0007409 152 0.016
negative regulation of gene expression GO:0010629 65 0.016
spermatid development GO:0007286 2 0.016
tube closure GO:0060606 1 0.016
head development GO:0060322 303 0.016
response to antibiotic GO:0046677 1 0.016
rna stabilization GO:0043489 4 0.016
neuron differentiation GO:0030182 353 0.016
positive regulation of chromosome organization GO:2001252 1 0.015
negative regulation of catabolic process GO:0009895 3 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
regulation of chromosome segregation GO:0051983 1 0.015
vasculature development GO:0001944 278 0.015
centrosome cycle GO:0007098 1 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
mitotic g2 dna damage checkpoint GO:0007095 3 0.015
cell cycle arrest GO:0007050 1 0.015
regulation of exocytosis GO:0017157 1 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
primitive hemopoiesis GO:0060215 27 0.015
macromolecule modification GO:0043412 111 0.015
nuclear import GO:0051170 3 0.015
mrna processing GO:0006397 14 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.015
system process GO:0003008 185 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
entrainment of circadian clock GO:0009649 2 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
autophagy GO:0006914 4 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
epithelial cell morphogenesis GO:0003382 2 0.014
membrane invagination GO:0010324 1 0.014
regulation of response to stimulus GO:0048583 269 0.014
protein localization to plasma membrane GO:0072659 1 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
protein complex disassembly GO:0043241 1 0.014
embryonic skeletal system development GO:0048706 97 0.014
positive regulation of wound healing GO:0090303 1 0.014
centrosome duplication GO:0051298 1 0.014
apoptotic process GO:0006915 116 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
mononuclear cell proliferation GO:0032943 1 0.014
centrosome organization GO:0051297 1 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
exocytosis GO:0006887 1 0.014
cell cycle g2 m phase transition GO:0044839 4 0.014
histone deacetylation GO:0016575 2 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of molecular function GO:0065009 70 0.014
establishment of localization GO:0051234 244 0.014
female meiotic division GO:0007143 2 0.014
single organism membrane fusion GO:0044801 2 0.013
nuclear export GO:0051168 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
response to organic substance GO:0010033 153 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
apoptotic process involved in development GO:1902742 2 0.013
sequestering of calcium ion GO:0051208 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
phosphorus metabolic process GO:0006793 109 0.013
digestive tract development GO:0048565 265 0.013
protein modification by small protein conjugation or removal GO:0070647 14 0.013
cell death GO:0008219 121 0.013
positive regulation of gene expression GO:0010628 71 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
response to external stimulus GO:0009605 264 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
organic substance catabolic process GO:1901575 28 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
generation of neurons GO:0048699 385 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
positive regulation of immune effector process GO:0002699 3 0.013
secondary metabolic process GO:0019748 3 0.012
tissue remodeling GO:0048771 4 0.012
response to glucocorticoid GO:0051384 1 0.012
regulation of cytokine production GO:0001817 3 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
cilium morphogenesis GO:0060271 85 0.012
regulation of protein catabolic process GO:0042176 1 0.012
erythrocyte maturation GO:0043249 8 0.012
wound healing GO:0042060 90 0.012
meiotic nuclear division GO:0007126 4 0.012
optic placode formation GO:0001743 4 0.012
regulation of blood pressure GO:0008217 1 0.012
cell matrix adhesion GO:0007160 4 0.012
leukocyte homeostasis GO:0001776 2 0.012
double strand break repair GO:0006302 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
myeloid cell homeostasis GO:0002262 56 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
programmed cell death GO:0012501 119 0.012
phagocytosis engulfment GO:0006911 1 0.012
protein k48 linked ubiquitination GO:0070936 1 0.012
sensory organ development GO:0007423 393 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
positive regulation of histone modification GO:0031058 1 0.012
sensory perception of touch GO:0050975 2 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of wound healing GO:0061041 2 0.011
ameboidal type cell migration GO:0001667 143 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
embryonic hemopoiesis GO:0035162 53 0.011
neuron development GO:0048666 262 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
cell aging GO:0007569 2 0.011
cellular protein complex assembly GO:0043623 19 0.011
cellular response to nutrient levels GO:0031669 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
cell substrate junction assembly GO:0007044 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
myeloid leukocyte mediated immunity GO:0002444 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
regulation of jak stat cascade GO:0046425 3 0.011
response to ketone GO:1901654 1 0.011
organelle fusion GO:0048284 3 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
stem cell division GO:0017145 1 0.011
regulation of cell motility GO:2000145 46 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
neuron projection morphogenesis GO:0048812 161 0.010
response to hexose GO:0009746 3 0.010
response to hydrogen peroxide GO:0042542 3 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
establishment of localization in cell GO:0051649 77 0.010
neurotransmitter transport GO:0006836 2 0.010
dna modification GO:0006304 8 0.010
carbohydrate homeostasis GO:0033500 1 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
gene silencing by rna GO:0031047 4 0.010
negative regulation of mitosis GO:0045839 3 0.010
transport GO:0006810 220 0.010
cytokinesis GO:0000910 3 0.010
lamellipodium assembly GO:0030032 1 0.010
response to glucose GO:0009749 3 0.010

gtf2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.011
muscular disease DOID:0080000 0 0.011
disease of anatomical entity DOID:7 0 0.011
myopathy DOID:423 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011