Danio rerio

0 known processes

gtf2b

general transcription factor IIB

(Aliases: zgc:66258,wu:fc44c11)

gtf2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.310
regulation of meiotic cell cycle GO:0051445 1 0.257
larval development GO:0002164 2 0.199
regulation of primary metabolic process GO:0080090 311 0.143
Fly
organelle organization GO:0006996 227 0.133
response to chemical GO:0042221 320 0.123
nucleobase containing compound metabolic process GO:0006139 274 0.116
Fly
cell motility GO:0048870 244 0.113
cellular nitrogen compound metabolic process GO:0034641 290 0.108
Fly
cell projection morphogenesis GO:0048858 244 0.107
embryo development ending in birth or egg hatching GO:0009792 271 0.104
Worm
positive regulation of cellular process GO:0048522 201 0.103
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.099
transcription dna templated GO:0006351 181 0.096
Fly
positive regulation of biological process GO:0048518 253 0.093
nucleic acid metabolic process GO:0090304 244 0.091
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.089
modification dependent protein catabolic process GO:0019941 3 0.089
cell cycle g1 s phase transition GO:0044843 1 0.086
locomotion GO:0040011 313 0.086
meiotic chromosome segregation GO:0045132 3 0.085
modification dependent macromolecule catabolic process GO:0043632 3 0.085
regulation of cell shape GO:0008360 1 0.084
regulation of multicellular organismal process GO:0051239 277 0.080
positive regulation of cell cycle GO:0045787 3 0.080
cellular component movement GO:0006928 335 0.077
nuclear division GO:0000280 23 0.073
g1 s transition of mitotic cell cycle GO:0000082 1 0.072
negative regulation of cellular process GO:0048523 283 0.067
development of primary female sexual characteristics GO:0046545 4 0.066
cell migration GO:0016477 237 0.066
nucleic acid templated transcription GO:0097659 181 0.063
Fly
cellular component morphogenesis GO:0032989 336 0.062
single organism organelle organization GO:1902589 199 0.061
regulation of cellular metabolic process GO:0031323 320 0.060
Fly
cell projection organization GO:0030030 284 0.060
response to stress GO:0006950 263 0.059
ubiquitin dependent protein catabolic process GO:0006511 3 0.059
response to uv GO:0009411 3 0.059
localization of cell GO:0051674 244 0.058
response to external stimulus GO:0009605 264 0.057
cell morphogenesis GO:0000902 289 0.056
nitrogen compound metabolic process GO:0006807 319 0.056
Fly
regulation of mrna processing GO:0050684 3 0.056
gene expression GO:0010467 252 0.056
Fly
cellular protein catabolic process GO:0044257 4 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.053
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.053
meiosis i GO:0007127 1 0.050
regulation of developmental process GO:0050793 247 0.049
protein metabolic process GO:0019538 183 0.047
chromosome organization GO:0051276 31 0.046
female gonad development GO:0008585 4 0.046
protein k48 linked ubiquitination GO:0070936 1 0.044
dna templated transcription elongation GO:0006354 3 0.044
cortical actin cytoskeleton organization GO:0030866 1 0.042
negative regulation of biological process GO:0048519 304 0.041
response to abiotic stimulus GO:0009628 122 0.041
regulation of biological quality GO:0065008 263 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
organic substance biosynthetic process GO:1901576 289 0.040
Fly
heterocycle metabolic process GO:0046483 290 0.040
Fly
chromosome organization involved in meiosis GO:0070192 1 0.040
cellular macromolecule metabolic process GO:0044260 391 0.039
Fly
response to biotic stimulus GO:0009607 97 0.039
meiotic cell cycle process GO:1903046 3 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.038
Fly
lipid homeostasis GO:0055088 3 0.038
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.036
regulation of metabolic process GO:0019222 359 0.036
Fly
establishment of localization GO:0051234 244 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.034
Fly
multi organism process GO:0051704 134 0.034
double strand break repair via homologous recombination GO:0000724 1 0.034
regulation of multicellular organismal development GO:2000026 223 0.033
regulation of cell differentiation GO:0045595 142 0.032
death GO:0016265 121 0.032
single organism reproductive process GO:0044702 40 0.032
autophagy GO:0006914 4 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
Fly
single organism localization GO:1902578 225 0.031
neuron development GO:0048666 262 0.031
female sex differentiation GO:0046660 4 0.031
cellular biosynthetic process GO:0044249 286 0.031
Fly
organic cyclic compound metabolic process GO:1901360 301 0.031
Fly
sensory organ development GO:0007423 393 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
Fly
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of cell proliferation GO:0042127 37 0.030
regulation of rna metabolic process GO:0051252 224 0.030
Fly
regulation of gene expression GO:0010468 265 0.030
Fly
heterocycle biosynthetic process GO:0018130 215 0.029
Fly
cellular protein metabolic process GO:0044267 129 0.029
regulation of transcription dna templated GO:0006355 213 0.029
Fly
cellular response to organic substance GO:0071310 105 0.029
compound eye development GO:0048749 2 0.029
regulation of synapse organization GO:0050807 3 0.028
rna biosynthetic process GO:0032774 181 0.028
Fly
mitochondrion organization GO:0007005 4 0.028
regulation of chromosome segregation GO:0051983 1 0.028
positive regulation of catabolic process GO:0009896 4 0.027
single fertilization GO:0007338 3 0.027
mitotic cell cycle GO:0000278 64 0.027
recombinational repair GO:0000725 1 0.027
positive regulation of chromatin modification GO:1903310 1 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.027
Fly
response to external biotic stimulus GO:0043207 97 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
negative regulation of synapse assembly GO:0051964 2 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
single organism metabolic process GO:0044710 217 0.026
rna metabolic process GO:0016070 219 0.026
Fly
transport GO:0006810 220 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
Fly
fertilization GO:0009566 3 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.025
Fly
neuroblast proliferation GO:0007405 2 0.025
response to other organism GO:0051707 97 0.025
cell part morphogenesis GO:0032990 246 0.025
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
Fly
meiosis ii GO:0007135 1 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
maintenance of location GO:0051235 4 0.024
cellular response to radiation GO:0071478 4 0.024
vasculature development GO:0001944 278 0.023
dna templated transcription initiation GO:0006352 1 0.023
Fly
generation of neurons GO:0048699 385 0.022
cellular response to starvation GO:0009267 1 0.022
regulation of reproductive process GO:2000241 4 0.022
regulation of protein complex assembly GO:0043254 3 0.022
aging GO:0007568 2 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of gene expression epigenetic GO:0040029 11 0.022
organelle fission GO:0048285 23 0.022
microtubule based process GO:0007017 60 0.022
regulation of cellular component organization GO:0051128 86 0.022
protein secretion GO:0009306 1 0.022
double strand break repair GO:0006302 3 0.021
heart development GO:0007507 313 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
Fly
cellular response to chemical stimulus GO:0070887 157 0.021
signal transduction GO:0007165 455 0.021
lipid storage GO:0019915 1 0.020
response to temperature stimulus GO:0009266 15 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
cell cycle GO:0007049 93 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.020
chordate embryonic development GO:0043009 271 0.020
neuron differentiation GO:0030182 353 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
post golgi vesicle mediated transport GO:0006892 1 0.020
regulation of response to stimulus GO:0048583 269 0.020
blood vessel development GO:0001568 246 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of signaling GO:0023051 235 0.019
negative regulation of metabolic process GO:0009892 86 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular response to light stimulus GO:0071482 4 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
proteolysis GO:0006508 38 0.019
positive regulation of gene expression GO:0010628 71 0.018
cellular response to nutrient levels GO:0031669 2 0.018
apoptotic process GO:0006915 116 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
developmental growth GO:0048589 166 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
cytoskeleton organization GO:0007010 96 0.018
membrane fusion GO:0061025 2 0.018
mrna metabolic process GO:0016071 20 0.018
positive regulation of transport GO:0051050 2 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of biosynthetic process GO:0009889 250 0.018
Fly
single organism membrane fusion GO:0044801 2 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
cellular component assembly GO:0022607 170 0.017
eye development GO:0001654 277 0.017
regulation of organelle organization GO:0033043 29 0.017
apoptotic process involved in development GO:1902742 2 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
Fly
microtubule cytoskeleton organization GO:0000226 33 0.016
gene silencing GO:0016458 4 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
embryonic organ development GO:0048568 381 0.016
mononuclear cell proliferation GO:0032943 1 0.016
response to organic substance GO:0010033 153 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
macromolecule modification GO:0043412 111 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of apoptotic process GO:0042981 98 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
regulation of protein catabolic process GO:0042176 1 0.015
mitochondrial transport GO:0006839 2 0.015
hemopoiesis GO:0030097 183 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
blood vessel morphogenesis GO:0048514 216 0.015
macroautophagy GO:0016236 1 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
muscle organ development GO:0007517 101 0.015
regulation of synapse assembly GO:0051963 3 0.015
protein phosphorylation GO:0006468 47 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
posttranscriptional gene silencing GO:0016441 3 0.015
cellular protein modification process GO:0006464 100 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
mitotic nuclear division GO:0007067 18 0.015
response to lipid GO:0033993 60 0.014
programmed cell death GO:0012501 119 0.014
neuron projection extension GO:1990138 45 0.014
cell cycle process GO:0022402 53 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
response to heat GO:0009408 6 0.014
digestive tract development GO:0048565 265 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
intracellular mrna localization GO:0008298 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
hatching GO:0035188 4 0.014
interspecies interaction between organisms GO:0044419 4 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
anterior posterior pattern specification GO:0009952 152 0.014
biological adhesion GO:0022610 40 0.014
lipid metabolic process GO:0006629 52 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of inflammatory response GO:0050727 2 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
immune system development GO:0002520 191 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
regulation of tube size GO:0035150 2 0.014
histone h3 k4 methylation GO:0051568 2 0.014
mitotic cell cycle process GO:1903047 48 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
protein polyubiquitination GO:0000209 4 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
stem cell proliferation GO:0072089 4 0.013
microtubule based movement GO:0007018 33 0.013
myeloid cell differentiation GO:0030099 86 0.013
spermatid development GO:0007286 2 0.013
homeostatic process GO:0042592 142 0.013
regulation of signal transduction GO:0009966 225 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
determination of left right symmetry GO:0007368 179 0.013
multicellular organism reproduction GO:0032504 35 0.013
regulation of cell activation GO:0050865 1 0.013
regionalization GO:0003002 274 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
response to topologically incorrect protein GO:0035966 2 0.013
positive regulation of signaling GO:0023056 56 0.013
neuron projection morphogenesis GO:0048812 161 0.013
gastrulation GO:0007369 208 0.013
protein modification process GO:0036211 100 0.013
regulation of blood vessel size GO:0050880 2 0.013
atp catabolic process GO:0006200 4 0.013
positive regulation of signal transduction GO:0009967 56 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
acylglycerol homeostasis GO:0055090 2 0.012
phagocytosis GO:0006909 3 0.012
regulation of cell cycle GO:0051726 52 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
protein localization to nucleus GO:0034504 3 0.012
determination of bilateral symmetry GO:0009855 204 0.012
intracellular signal transduction GO:0035556 85 0.012
segmentation GO:0035282 97 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of binding GO:0051098 3 0.012
Fly
cell growth GO:0016049 57 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
pronuclear migration GO:0035046 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
Fly
positive regulation of metabolic process GO:0009893 108 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
gtp metabolic process GO:0046039 4 0.011
negative regulation of molecular function GO:0044092 23 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
protein import GO:0017038 3 0.011
golgi vesicle transport GO:0048193 3 0.011
cell proliferation GO:0008283 80 0.011
angiogenesis GO:0001525 158 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
negative regulation of gene expression GO:0010629 65 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
response to wounding GO:0009611 116 0.011
negative regulation of signal transduction GO:0009968 94 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Fly
actin filament based movement GO:0030048 1 0.011
developmental programmed cell death GO:0010623 4 0.011
cytoplasm organization GO:0007028 4 0.011
growth GO:0040007 174 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
defense response GO:0006952 47 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
pole plasm assembly GO:0007315 4 0.011
multi organism cellular process GO:0044764 2 0.011
cell adhesion GO:0007155 40 0.011
reproduction GO:0000003 40 0.011
somitogenesis GO:0001756 87 0.011
cell division GO:0051301 20 0.010
single organism nuclear import GO:1902593 3 0.010
cell death GO:0008219 121 0.010
establishment of organelle localization GO:0051656 45 0.010
developmental cell growth GO:0048588 52 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
response to organic cyclic compound GO:0014070 51 0.010
response to light stimulus GO:0009416 46 0.010
cell cycle arrest GO:0007050 1 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.010
post embryonic morphogenesis GO:0009886 4 0.010
positive regulation of secretion by cell GO:1903532 1 0.010

gtf2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
cancer DOID:162 0 0.020
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.011