Danio rerio

0 known processes

gtf2f2a

general transcription factor IIF, polypeptide 2a

(Aliases: wu:fb39a05,zgc:86775,MGC174761,gtf2f2)

gtf2f2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.579
cellular aromatic compound metabolic process GO:0006725 295 0.335
Fly
gene expression GO:0010467 252 0.263
Fly
single organism organelle organization GO:1902589 199 0.202
negative regulation of biological process GO:0048519 304 0.194
positive regulation of translation GO:0045727 1 0.188
protein acetylation GO:0006473 2 0.187
heterocycle metabolic process GO:0046483 290 0.184
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.177
Fly
negative regulation of gene expression GO:0010629 65 0.165
alternative mrna splicing via spliceosome GO:0000380 1 0.160
dna templated transcription initiation GO:0006352 1 0.159
Fly
negative regulation of cellular process GO:0048523 283 0.155
regulation of metabolic process GO:0019222 359 0.155
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.143
Fly
organelle organization GO:0006996 227 0.139
regulation of mrna processing GO:0050684 3 0.133
rna biosynthetic process GO:0032774 181 0.133
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.132
embryo development ending in birth or egg hatching GO:0009792 271 0.112
Worm
cellular macromolecule metabolic process GO:0044260 391 0.103
Fly
organic substance biosynthetic process GO:1901576 289 0.102
Fly
regionalization GO:0003002 274 0.100
nitrogen compound metabolic process GO:0006807 319 0.099
Fly
regulation of transcription dna templated GO:0006355 213 0.094
Fly
regulation of gene expression GO:0010468 265 0.093
Fly
negative regulation of protein kinase activity GO:0006469 4 0.091
response to stress GO:0006950 263 0.088
meiotic chromosome segregation GO:0045132 3 0.083
peptidyl lysine acetylation GO:0018394 2 0.079
cellular nitrogen compound metabolic process GO:0034641 290 0.078
Fly
internal protein amino acid acetylation GO:0006475 2 0.074
meiotic cell cycle process GO:1903046 3 0.073
regulation of rna biosynthetic process GO:2001141 213 0.073
Fly
cellular biosynthetic process GO:0044249 286 0.072
Fly
meiotic nuclear division GO:0007126 4 0.072
nucleobase containing compound metabolic process GO:0006139 274 0.070
Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.070
nucleic acid templated transcription GO:0097659 181 0.070
Fly
cell surface receptor signaling pathway GO:0007166 325 0.067
cellular response to lipopolysaccharide GO:0071222 3 0.065
microtubule based process GO:0007017 60 0.063
amine metabolic process GO:0009308 2 0.063
regulation of cellular metabolic process GO:0031323 320 0.062
Fly
single organism metabolic process GO:0044710 217 0.057
organic cyclic compound metabolic process GO:1901360 301 0.055
Fly
protein acylation GO:0043543 3 0.054
histone modification GO:0016570 20 0.054
transcription from rna polymerase ii promoter GO:0006366 80 0.054
Fly
muscle cell differentiation GO:0042692 139 0.053
regulation of primary metabolic process GO:0080090 311 0.052
Fly
transcription dna templated GO:0006351 181 0.052
Fly
internal peptidyl lysine acetylation GO:0018393 2 0.052
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.051
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.051
Fly
rna localization GO:0006403 4 0.051
protein metabolic process GO:0019538 183 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.049
Fly
positive regulation of gene expression GO:0010628 71 0.049
Fly
regulation of cell communication GO:0010646 232 0.048
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.048
organic cyclic compound biosynthetic process GO:1901362 223 0.047
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.046
rna metabolic process GO:0016070 219 0.045
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.045
negative regulation of chromosome organization GO:2001251 1 0.044
regulation of multicellular organismal development GO:2000026 223 0.044
macromolecule biosynthetic process GO:0009059 227 0.044
Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.042
Fly
aromatic compound biosynthetic process GO:0019438 217 0.042
Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.042
ribonucleoside monophosphate catabolic process GO:0009158 4 0.042
cellular component morphogenesis GO:0032989 336 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.040
nucleic acid metabolic process GO:0090304 244 0.040
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
Fly
negative regulation of kinase activity GO:0033673 4 0.039
cytoskeleton organization GO:0007010 96 0.039
cellular ketone metabolic process GO:0042180 11 0.039
regulation of endothelial cell proliferation GO:0001936 1 0.039
growth GO:0040007 174 0.038
signal transduction GO:0007165 455 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
regulation of biological quality GO:0065008 263 0.037
double strand break repair via homologous recombination GO:0000724 1 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.037
response to drug GO:0042493 3 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
microtubule organizing center organization GO:0031023 1 0.036
response to external stimulus GO:0009605 264 0.036
negative regulation of cellular metabolic process GO:0031324 77 0.036
cellular component movement GO:0006928 335 0.036
atp catabolic process GO:0006200 4 0.036
biosynthetic process GO:0009058 294 0.036
Fly
regulation of binding GO:0051098 3 0.036
protein complex subunit organization GO:0071822 46 0.036
Fly
regulation of signaling GO:0023051 235 0.034
regulation of response to stimulus GO:0048583 269 0.034
regulation of cellular amine metabolic process GO:0033238 0 0.033
protein localization to nucleus GO:0034504 3 0.033
stem cell proliferation GO:0072089 4 0.033
establishment of localization GO:0051234 244 0.033
Worm
regulation of signal transduction GO:0009966 225 0.033
positive regulation of nuclease activity GO:0032075 1 0.033
cell motility GO:0048870 244 0.032
regulation of protein complex assembly GO:0043254 3 0.032
Fly
negative regulation of metabolic process GO:0009892 86 0.032
localization of cell GO:0051674 244 0.032
dna templated transcription elongation GO:0006354 3 0.032
Fly
developmental process involved in reproduction GO:0003006 27 0.032
cellular response to stress GO:0033554 62 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
Fly
locomotion GO:0040011 313 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.031
Fly
regulation of receptor activity GO:0010469 2 0.030
anterior posterior pattern specification GO:0009952 152 0.030
oxoacid metabolic process GO:0043436 31 0.029
cell proliferation GO:0008283 80 0.029
multicellular organismal reproductive process GO:0048609 35 0.029
small molecule metabolic process GO:0044281 77 0.029
regulation of epithelial cell proliferation GO:0050678 3 0.029
response to glucose GO:0009749 3 0.028
muscle structure development GO:0061061 196 0.028
hormone transport GO:0009914 2 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
rrna catabolic process GO:0016075 1 0.028
regulation of mrna splicing via spliceosome GO:0048024 3 0.028
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
Fly
positive regulation of protein complex assembly GO:0031334 2 0.027
Fly
hormone secretion GO:0046879 2 0.027
cell migration GO:0016477 237 0.027
protein polymerization GO:0051258 4 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
maintenance of location GO:0051235 4 0.026
spindle assembly GO:0051225 2 0.026
cellular protein metabolic process GO:0044267 129 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
cognition GO:0050890 1 0.026
pole plasm assembly GO:0007315 4 0.026
oocyte anterior posterior axis specification GO:0007314 4 0.026
cellular response to dna damage stimulus GO:0006974 24 0.025
regulation of rna metabolic process GO:0051252 224 0.025
Fly
negative regulation of response to stimulus GO:0048585 104 0.025
cellular response to external stimulus GO:0071496 2 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
chromosome organization involved in meiosis GO:0070192 1 0.025
negative regulation of rna biosynthetic process GO:1902679 45 0.025
negative regulation of rna metabolic process GO:0051253 48 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.024
aging GO:0007568 2 0.024
response to organic substance GO:0010033 153 0.023
regulation of mrna metabolic process GO:1903311 6 0.023
lipid storage GO:0019915 1 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.023
golgi vesicle transport GO:0048193 3 0.023
single organism reproductive process GO:0044702 40 0.023
negative regulation of nucleic acid templated transcription GO:1903507 45 0.023
cell cycle GO:0007049 93 0.022
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.022
protein complex disassembly GO:0043241 1 0.022
mitotic cell cycle GO:0000278 64 0.022
negative regulation of chromatin modification GO:1903309 1 0.022
regulation of synapse organization GO:0050807 3 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of autophagy GO:0010506 3 0.021
negative regulation of neural precursor cell proliferation GO:2000178 1 0.021
cellular component assembly GO:0022607 170 0.021
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
response to chemical GO:0042221 320 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
Fly
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.021
cellular amino acid metabolic process GO:0006520 7 0.020
cytokinesis GO:0000910 3 0.020
negative regulation of biosynthetic process GO:0009890 55 0.020
cell cycle process GO:0022402 53 0.020
regulation of synapse assembly GO:0051963 3 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
immune system process GO:0002376 241 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
Fly
single organism membrane fusion GO:0044801 2 0.020
proteasomal protein catabolic process GO:0010498 2 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
Fly
regulation of developmental process GO:0050793 247 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
Fly
cellular response to biotic stimulus GO:0071216 3 0.019
single organism cellular localization GO:1902580 46 0.019
erk1 and erk2 cascade GO:0070371 4 0.019
negative regulation of signaling GO:0023057 96 0.019
multi organism process GO:0051704 134 0.019
regulation of cellular component organization GO:0051128 86 0.019
Fly
double strand break repair GO:0006302 3 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
organic acid metabolic process GO:0006082 31 0.018
regulation of translational initiation GO:0006446 1 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
ncrna catabolic process GO:0034661 1 0.018
chromatin modification GO:0016568 21 0.018
regulation of oocyte development GO:0060281 3 0.018
cellular component biogenesis GO:0044085 178 0.018
Fly
cellular amine metabolic process GO:0044106 2 0.018
response to abiotic stimulus GO:0009628 122 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
blood vessel morphogenesis GO:0048514 216 0.018
response to carbohydrate GO:0009743 3 0.018
neuroblast proliferation GO:0007405 2 0.018
cell fate commitment GO:0045165 99 0.017
mitotic g2 dna damage checkpoint GO:0007095 3 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
segmentation GO:0035282 97 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
translational initiation GO:0006413 3 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
negative regulation of signal transduction GO:0009968 94 0.017
meiosis i GO:0007127 1 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
Fly
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.017
Fly
neuromuscular synaptic transmission GO:0007274 2 0.017
regulation of reproductive process GO:2000241 4 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
negative regulation of transcription dna templated GO:0045892 45 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
mitotic g2 m transition checkpoint GO:0044818 3 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
negative regulation of histone modification GO:0031057 1 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
regulation of organelle organization GO:0033043 29 0.016
chordate embryonic development GO:0043009 271 0.016
apoptotic process GO:0006915 116 0.016
cellular response to starvation GO:0009267 1 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
protein stabilization GO:0050821 2 0.016
cytoplasm organization GO:0007028 4 0.016
negative regulation of leukocyte differentiation GO:1902106 1 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
nuclear transport GO:0051169 4 0.016
neuron differentiation GO:0030182 353 0.016
positive regulation of transport GO:0051050 2 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
regulation of biosynthetic process GO:0009889 250 0.015
Fly
sexual reproduction GO:0019953 36 0.015
cellular protein modification process GO:0006464 100 0.015
negative regulation of rna splicing GO:0033119 1 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.015
single organism localization GO:1902578 225 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
response to external biotic stimulus GO:0043207 97 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
myeloid cell differentiation GO:0030099 86 0.015
centrosome organization GO:0051297 1 0.015
regulation of cell differentiation GO:0045595 142 0.015
cellular macromolecular complex assembly GO:0034622 24 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
camera type eye development GO:0043010 222 0.015
organelle assembly GO:0070925 110 0.014
autophagy GO:0006914 4 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
Fly
multicellular organism growth GO:0035264 4 0.014
regulation of cytokine production GO:0001817 3 0.014
regulation of cell projection assembly GO:0060491 4 0.014
gamete generation GO:0007276 33 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
rna splicing GO:0008380 16 0.014
spermatid differentiation GO:0048515 2 0.014
neuron development GO:0048666 262 0.014
protein import into nucleus GO:0006606 3 0.014
system process GO:0003008 185 0.014
nuclear division GO:0000280 23 0.014
positive regulation of nucleic acid templated transcription GO:1903508 57 0.014
Fly
single organism nuclear import GO:1902593 3 0.014
mesenchyme development GO:0060485 127 0.014
mitochondrion organization GO:0007005 4 0.014
recombinational repair GO:0000725 1 0.014
positive regulation of transcription dna templated GO:0045893 57 0.013
Fly
macromolecule modification GO:0043412 111 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
Fly
pharyngeal muscle development GO:0043282 4 0.013
female meiotic division GO:0007143 2 0.013
protein import GO:0017038 3 0.013
chemotaxis GO:0006935 104 0.013
regulation of protein transport GO:0051223 3 0.013
head development GO:0060322 303 0.013
spermatid development GO:0007286 2 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Fly
germ cell development GO:0007281 22 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
cellular protein catabolic process GO:0044257 4 0.013
cell death GO:0008219 121 0.013
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.013
intracellular mrna localization GO:0008298 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
dna metabolic process GO:0006259 27 0.013
single fertilization GO:0007338 3 0.013
sensory organ development GO:0007423 393 0.013
peptide transport GO:0015833 1 0.013
locomotor rhythm GO:0045475 3 0.012
response to other organism GO:0051707 97 0.012
response to ketone GO:1901654 1 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
mrna metabolic process GO:0016071 20 0.012
protein dephosphorylation GO:0006470 3 0.012
microtubule polymerization GO:0046785 2 0.012
protein modification by small protein removal GO:0070646 1 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
Fly
regulation of wound healing GO:0061041 2 0.012
positive regulation of catabolic process GO:0009896 4 0.012
positive regulation of cell activation GO:0050867 1 0.012
mitotic cell cycle process GO:1903047 48 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
dna biosynthetic process GO:0071897 3 0.012
striated muscle cell differentiation GO:0051146 129 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
organelle fusion GO:0048284 3 0.012
immune system development GO:0002520 191 0.012
phosphorylation GO:0016310 69 0.012
regulation of cell shape GO:0008360 1 0.012
regulation of cell death GO:0010941 103 0.012
mechanosensory behavior GO:0007638 2 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
covalent chromatin modification GO:0016569 20 0.012
specification of symmetry GO:0009799 204 0.012
protein modification process GO:0036211 100 0.012
skeletal system development GO:0001501 181 0.012
nuclear import GO:0051170 3 0.012
negative regulation of cell communication GO:0010648 96 0.012
negative regulation of developmental process GO:0051093 65 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
mrna catabolic process GO:0006402 6 0.011
regulation of localization GO:0032879 104 0.011
negative regulation of catalytic activity GO:0043086 21 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
centrosome cycle GO:0007098 1 0.011
megakaryocyte differentiation GO:0030219 1 0.011
generation of neurons GO:0048699 385 0.011
response to biotic stimulus GO:0009607 97 0.011
positive regulation of cell cycle GO:0045787 3 0.011
response to endogenous stimulus GO:0009719 83 0.011
macromolecule localization GO:0033036 54 0.011
protein phosphorylation GO:0006468 47 0.011
meiosis ii GO:0007135 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
negative regulation of epithelial cell migration GO:0010633 1 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
regulation of molecular function GO:0065009 70 0.011
chromatin organization GO:0006325 22 0.011
carbohydrate homeostasis GO:0033500 1 0.010
actin filament based process GO:0030029 64 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
death GO:0016265 121 0.010
regulation of protein polymerization GO:0032271 2 0.010
cellular component disassembly GO:0022411 1 0.010
chemosensory behavior GO:0007635 1 0.010
positive regulation of biological process GO:0048518 253 0.010
Fly
glucose homeostasis GO:0042593 1 0.010
macromolecular complex disassembly GO:0032984 1 0.010
determination of bilateral symmetry GO:0009855 204 0.010
cell part morphogenesis GO:0032990 246 0.010
alpha amino acid metabolic process GO:1901605 3 0.010
regulation of protein binding GO:0043393 3 0.010

gtf2f2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.012
musculoskeletal system disease DOID:17 0 0.011