Danio rerio

0 known processes

h2afvl

H2A histone family, member V, like

(Aliases: im:6896397,h2afza,h2av)

h2afvl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna processing GO:0050684 3 0.467
aging GO:0007568 2 0.339
neuron differentiation GO:0030182 353 0.290
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 1 0.287
regulation of endothelial cell proliferation GO:0001936 1 0.280
regulation of rna metabolic process GO:0051252 224 0.277
heterocycle metabolic process GO:0046483 290 0.240
nucleobase containing compound metabolic process GO:0006139 274 0.237
nucleic acid metabolic process GO:0090304 244 0.230
cellular aromatic compound metabolic process GO:0006725 295 0.228
organic cyclic compound metabolic process GO:1901360 301 0.213
response to stress GO:0006950 263 0.211
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.198
regulation of mrna splicing via spliceosome GO:0048024 3 0.183
larval development GO:0002164 2 0.176
cellular nitrogen compound metabolic process GO:0034641 290 0.169
alternative mrna splicing via spliceosome GO:0000380 1 0.152
nuclear transport GO:0051169 4 0.140
regulation of cellular metabolic process GO:0031323 320 0.134
cellular macromolecule metabolic process GO:0044260 391 0.132
nucleocytoplasmic transport GO:0006913 4 0.125
regulation of biological quality GO:0065008 263 0.125
regulation of metabolic process GO:0019222 359 0.121
nitrogen compound metabolic process GO:0006807 319 0.116
positive regulation of nuclease activity GO:0032075 1 0.113
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.109
cellular component biogenesis GO:0044085 178 0.107
mrna metabolic process GO:0016071 20 0.105
positive regulation of endothelial cell proliferation GO:0001938 1 0.102
negative regulation of cellular process GO:0048523 283 0.100
single organism organelle organization GO:1902589 199 0.098
negative regulation of mrna processing GO:0050686 1 0.096
microtubule cytoskeleton organization GO:0000226 33 0.092
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.087
nuclear export GO:0051168 1 0.086
cellular response to molecule of bacterial origin GO:0071219 3 0.086
regulation of transcription dna templated GO:0006355 213 0.085
meiotic nuclear division GO:0007126 4 0.083
organelle organization GO:0006996 227 0.083
microtubule based process GO:0007017 60 0.077
regulation of primary metabolic process GO:0080090 311 0.077
nuclear division GO:0000280 23 0.076
spermatid development GO:0007286 2 0.074
homeostatic process GO:0042592 142 0.071
rna metabolic process GO:0016070 219 0.070
cellular response to lipopolysaccharide GO:0071222 3 0.070
regulation of nuclease activity GO:0032069 1 0.068
negative regulation of rna splicing GO:0033119 1 0.066
rna transport GO:0050658 2 0.065
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.064
positive regulation of epithelial cell proliferation GO:0050679 1 0.062
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.061
protein localization to nucleus GO:0034504 3 0.061
rna processing GO:0006396 25 0.061
cellular response to biotic stimulus GO:0071216 3 0.060
regulation of response to stimulus GO:0048583 269 0.059
regulation of developmental process GO:0050793 247 0.057
positive regulation of myeloid cell differentiation GO:0045639 2 0.056
regulation of chromosome segregation GO:0051983 1 0.056
establishment of organelle localization GO:0051656 45 0.055
maintenance of location GO:0051235 4 0.055
protein polymerization GO:0051258 4 0.054
transcription dna templated GO:0006351 181 0.053
regulation of macromolecule metabolic process GO:0060255 317 0.053
regulation of protein complex assembly GO:0043254 3 0.052
muscle structure development GO:0061061 196 0.052
regulation of epithelial cell proliferation GO:0050678 3 0.052
organic cyclic compound biosynthetic process GO:1901362 223 0.052
nuclear migration GO:0007097 3 0.052
negative regulation of cellular metabolic process GO:0031324 77 0.051
regionalization GO:0003002 274 0.051
cellular component assembly GO:0022607 170 0.051
regulation of multicellular organismal process GO:0051239 277 0.050
mitotic nuclear division GO:0007067 18 0.050
regulation of nucleocytoplasmic transport GO:0046822 2 0.050
organic substance biosynthetic process GO:1901576 289 0.049
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.048
cellular response to stress GO:0033554 62 0.047
regulation of binding GO:0051098 3 0.047
aromatic compound biosynthetic process GO:0019438 217 0.046
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.045
response to organic substance GO:0010033 153 0.045
cell surface receptor signaling pathway GO:0007166 325 0.044
regulation of biosynthetic process GO:0009889 250 0.044
maturation of ssu rrna GO:0030490 1 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
gene expression GO:0010467 252 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.041
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.041
homeostasis of number of cells GO:0048872 62 0.040
regulation of multicellular organismal development GO:2000026 223 0.038
regulation of gene expression GO:0010468 265 0.038
single organism nuclear import GO:1902593 3 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
regulation of anatomical structure morphogenesis GO:0022603 130 0.038
response to chemical GO:0042221 320 0.038
cytoskeleton organization GO:0007010 96 0.038
response to external stimulus GO:0009605 264 0.037
ribonucleoprotein complex biogenesis GO:0022613 13 0.037
nucleus organization GO:0006997 7 0.037
negative regulation of cellular biosynthetic process GO:0031327 55 0.037
regulation of rna biosynthetic process GO:2001141 213 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.034
positive regulation of macromolecule metabolic process GO:0010604 93 0.034
mitotic cell cycle GO:0000278 64 0.034
phosphorus metabolic process GO:0006793 109 0.034
cellular localization GO:0051641 97 0.034
negative regulation of biological process GO:0048519 304 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
circulatory system process GO:0003013 87 0.033
spermatid differentiation GO:0048515 2 0.033
positive regulation of translation GO:0045727 1 0.033
negative regulation of transcription dna templated GO:0045892 45 0.033
regulation of meiotic cell cycle GO:0051445 1 0.032
positive regulation of dna metabolic process GO:0051054 1 0.032
actin filament based process GO:0030029 64 0.032
protein import GO:0017038 3 0.032
positive regulation of cellular process GO:0048522 201 0.032
endothelial cell proliferation GO:0001935 11 0.032
cell aging GO:0007569 2 0.032
cell morphogenesis GO:0000902 289 0.031
cellular component assembly involved in morphogenesis GO:0010927 107 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.030
protein import into nucleus GO:0006606 3 0.030
nuclear import GO:0051170 3 0.030
striated muscle cell development GO:0055002 108 0.029
cellular biosynthetic process GO:0044249 286 0.029
negative regulation of gene expression GO:0010629 65 0.029
erythrocyte homeostasis GO:0034101 55 0.029
mrna processing GO:0006397 14 0.028
cellular component morphogenesis GO:0032989 336 0.028
regulation of signaling GO:0023051 235 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
cell projection organization GO:0030030 284 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
mrna splicing via spliceosome GO:0000398 10 0.028
nucleobase containing compound transport GO:0015931 2 0.027
cell motility GO:0048870 244 0.027
generation of neurons GO:0048699 385 0.027
organelle localization GO:0051640 49 0.027
mechanosensory behavior GO:0007638 2 0.026
rna export from nucleus GO:0006405 1 0.026
negative regulation of nucleic acid templated transcription GO:1903507 45 0.026
dna templated transcription elongation GO:0006354 3 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
cellular protein complex assembly GO:0043623 19 0.026
establishment of cell polarity GO:0030010 18 0.026
cellular catabolic process GO:0044248 27 0.026
cell cycle GO:0007049 93 0.025
single organism cellular localization GO:1902580 46 0.025
nucleic acid transport GO:0050657 2 0.025
spindle localization GO:0051653 12 0.025
establishment of localization in cell GO:0051649 77 0.025
cell death GO:0008219 121 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.024
cognition GO:0050890 1 0.024
immune system process GO:0002376 241 0.024
protein complex subunit organization GO:0071822 46 0.024
response to organic cyclic compound GO:0014070 51 0.024
mitotic cell cycle process GO:1903047 48 0.024
cellular response to lipid GO:0071396 39 0.024
negative regulation of mrna metabolic process GO:1903312 3 0.024
membrane invagination GO:0010324 1 0.024
muscle cell differentiation GO:0042692 139 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
cellular component movement GO:0006928 335 0.023
single organism localization GO:1902578 225 0.023
rna splicing via transesterification reactions GO:0000375 10 0.023
single organism metabolic process GO:0044710 217 0.023
protein targeting to nucleus GO:0044744 3 0.023
protein complex disassembly GO:0043241 1 0.023
cellular component maintenance GO:0043954 3 0.022
cell chemotaxis GO:0060326 17 0.022
regulation of receptor activity GO:0010469 2 0.022
establishment of rna localization GO:0051236 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of gene expression GO:0010628 71 0.022
actin polymerization or depolymerization GO:0008154 2 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
myeloid cell homeostasis GO:0002262 56 0.021
megakaryocyte differentiation GO:0030219 1 0.021
biosynthetic process GO:0009058 294 0.021
negative regulation of signal transduction GO:0009968 94 0.021
negative regulation of signaling GO:0023057 96 0.021
organelle fission GO:0048285 23 0.021
myeloid cell differentiation GO:0030099 86 0.021
actin cytoskeleton organization GO:0030036 63 0.021
regulation of cellular component organization GO:0051128 86 0.021
neuroblast proliferation GO:0007405 2 0.021
negative regulation of chromosome organization GO:2001251 1 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.020
muscle cell development GO:0055001 115 0.020
camera type eye development GO:0043010 222 0.020
signal transduction GO:0007165 455 0.020
regulation of erythrocyte differentiation GO:0045646 2 0.020
retina development in camera type eye GO:0060041 146 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
centrosome cycle GO:0007098 1 0.020
protein complex localization GO:0031503 1 0.020
sensory organ development GO:0007423 393 0.020
negative regulation of metabolic process GO:0009892 86 0.020
autophagy GO:0006914 4 0.019
regulation of cell shape GO:0008360 1 0.019
establishment of localization GO:0051234 244 0.019
nucleobase containing compound catabolic process GO:0034655 15 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
muscle organ development GO:0007517 101 0.019
cellular response to dna damage stimulus GO:0006974 24 0.019
brain development GO:0007420 293 0.018
regulation of signal transduction GO:0009966 225 0.018
amine metabolic process GO:0009308 2 0.018
cellular response to external stimulus GO:0071496 2 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
multi organism process GO:0051704 134 0.018
single organism reproductive process GO:0044702 40 0.018
response to oxygen containing compound GO:1901700 55 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.017
single fertilization GO:0007338 3 0.017
mrna 3 end processing GO:0031124 2 0.017
rna catabolic process GO:0006401 7 0.017
embryonic organ development GO:0048568 381 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
myofibril assembly GO:0030239 48 0.017
localization of cell GO:0051674 244 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.017
regulation of cell projection assembly GO:0060491 4 0.017
transport GO:0006810 220 0.016
nucleic acid templated transcription GO:0097659 181 0.016
cell substrate junction assembly GO:0007044 2 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
dna templated transcription initiation GO:0006352 1 0.016
cellular response to oxygen containing compound GO:1901701 20 0.016
eye development GO:0001654 277 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
regulation of protein binding GO:0043393 3 0.016
pronuclear migration GO:0035046 1 0.016
response to lipid GO:0033993 60 0.016
proteasomal protein catabolic process GO:0010498 2 0.015
fertilization GO:0009566 3 0.015
positive regulation of transport GO:0051050 2 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
spliceosomal snrnp assembly GO:0000387 2 0.015
meiotic chromosome segregation GO:0045132 3 0.015
protein complex assembly GO:0006461 30 0.015
double strand break repair GO:0006302 3 0.015
organic cyclic compound catabolic process GO:1901361 15 0.015
rna localization GO:0006403 4 0.015
establishment of mitotic spindle orientation GO:0000132 10 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.015
developmental process involved in reproduction GO:0003006 27 0.014
cell part morphogenesis GO:0032990 246 0.014
rna 3 end processing GO:0031123 2 0.014
regulation of rna splicing GO:0043484 8 0.014
regulation of mitotic cell cycle embryonic GO:0009794 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
organism emergence from protective structure GO:0071684 4 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
lamellipodium assembly GO:0030032 1 0.014
neuron projection morphogenesis GO:0048812 161 0.014
telomere organization GO:0032200 1 0.013
response to drug GO:0042493 3 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
neuron development GO:0048666 262 0.013
specification of symmetry GO:0009799 204 0.013
cellular response to organic substance GO:0071310 105 0.013
multicellular organism growth GO:0035264 4 0.013
response to ketone GO:1901654 1 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
ribosomal small subunit biogenesis GO:0042274 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of cell death GO:0010941 103 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
cell projection morphogenesis GO:0048858 244 0.013
macromolecular complex subunit organization GO:0043933 74 0.012
stem cell proliferation GO:0072089 4 0.012
growth GO:0040007 174 0.012
cellular protein catabolic process GO:0044257 4 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
muscle tissue development GO:0060537 110 0.012
organelle assembly GO:0070925 110 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
intracellular transport GO:0046907 32 0.012
microtubule organizing center organization GO:0031023 1 0.012
cell migration GO:0016477 237 0.012
telomere maintenance GO:0000723 1 0.012
regulation of cytokine production GO:0001817 3 0.012
female gonad development GO:0008585 4 0.012
establishment of spindle orientation GO:0051294 10 0.012
regulation of embryonic development GO:0045995 47 0.012
phagocytosis engulfment GO:0006911 1 0.012
central nervous system development GO:0007417 387 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
lipid storage GO:0019915 1 0.012
establishment of mitotic spindle localization GO:0040001 12 0.012
cellular amine metabolic process GO:0044106 2 0.012
system process GO:0003008 185 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
cell cycle process GO:0022402 53 0.012
mrna transport GO:0051028 2 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of jak stat cascade GO:0046425 3 0.011
microtubule polymerization GO:0046785 2 0.011
heart development GO:0007507 313 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
anterior posterior pattern specification GO:0009952 152 0.011
negative regulation of chromatin modification GO:1903309 1 0.011
cellular component disassembly GO:0022411 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
protein heterooligomerization GO:0051291 1 0.011
head development GO:0060322 303 0.011
macromolecule modification GO:0043412 111 0.011
establishment or maintenance of cell polarity GO:0007163 29 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.011
protein homooligomerization GO:0051260 3 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
establishment of spindle localization GO:0051293 12 0.011
actomyosin structure organization GO:0031032 53 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
neuron projection development GO:0031175 180 0.011
regulation of inflammatory response GO:0050727 2 0.011
chemotaxis GO:0006935 104 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
heart process GO:0003015 71 0.011
regulation of reproductive process GO:2000241 4 0.011
hemopoiesis GO:0030097 183 0.011
pharyngeal muscle development GO:0043282 4 0.011
phagocytosis GO:0006909 3 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
regulation of protein targeting GO:1903533 2 0.010
hematopoietic progenitor cell differentiation GO:0002244 23 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
striated muscle cell differentiation GO:0051146 129 0.010
positive regulation of biological process GO:0048518 253 0.010
organic substance catabolic process GO:1901575 28 0.010
protein depolymerization GO:0051261 1 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
regulation of growth rate GO:0040009 1 0.010
regulation of protein complex disassembly GO:0043244 1 0.010

h2afvl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010