Danio rerio

0 known processes

hccs

holocytochrome c synthase

(Aliases: hccsb,id:ibd1278,wu:fi43e01,wu:fb18h01,wu:fc64e12)

hccs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 4 0.646
small molecule metabolic process GO:0044281 77 0.285
mitochondrial transport GO:0006839 2 0.276
larval development GO:0002164 2 0.248
Worm
aging GO:0007568 2 0.240
Worm
cellular respiration GO:0045333 3 0.132
establishment of protein localization to organelle GO:0072594 4 0.115
oxoacid metabolic process GO:0043436 31 0.104
nucleocytoplasmic transport GO:0006913 4 0.103
nuclear transport GO:0051169 4 0.101
single organism transport GO:0044765 206 0.101
carboxylic acid metabolic process GO:0019752 22 0.095
transport GO:0006810 220 0.093
Worm
purine nucleotide biosynthetic process GO:0006164 20 0.090
organic cyclic compound metabolic process GO:1901360 301 0.090
cellular nitrogen compound metabolic process GO:0034641 290 0.089
dicarboxylic acid metabolic process GO:0043648 1 0.084
aromatic compound biosynthetic process GO:0019438 217 0.078
cellular component assembly GO:0022607 170 0.076
nucleobase containing compound metabolic process GO:0006139 274 0.075
organic cyclic compound biosynthetic process GO:1901362 223 0.074
gene expression GO:0010467 252 0.072
cellular nitrogen compound biosynthetic process GO:0044271 218 0.071
nitrogen compound metabolic process GO:0006807 319 0.070
response to drug GO:0042493 3 0.069
response to chemical GO:0042221 320 0.067
single organism localization GO:1902578 225 0.067
regulation of multicellular organismal process GO:0051239 277 0.066
positive regulation of transport GO:0051050 2 0.065
cellular aromatic compound metabolic process GO:0006725 295 0.063
cell death GO:0008219 121 0.063
organic acid metabolic process GO:0006082 31 0.063
organic substance biosynthetic process GO:1901576 289 0.060
response to stress GO:0006950 263 0.059
negative regulation of cellular process GO:0048523 283 0.059
negative regulation of protein kinase activity GO:0006469 4 0.056
cellular biosynthetic process GO:0044249 286 0.055
heterocycle metabolic process GO:0046483 290 0.054
growth GO:0040007 174 0.051
phosphorus metabolic process GO:0006793 109 0.051
phagocytosis GO:0006909 3 0.050
establishment of localization in cell GO:0051649 77 0.048
neuron development GO:0048666 262 0.048
cellular localization GO:0051641 97 0.047
morphogenesis of an epithelium GO:0002009 333 0.047
single organism metabolic process GO:0044710 217 0.046
extrinsic apoptotic signaling pathway GO:0097191 3 0.046
stem cell proliferation GO:0072089 4 0.041
developmental growth GO:0048589 166 0.041
positive regulation of biological process GO:0048518 253 0.041
nucleoside phosphate biosynthetic process GO:1901293 21 0.040
regulation of tube size GO:0035150 2 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.039
Worm
positive regulation of metabolic process GO:0009893 108 0.039
cellular component movement GO:0006928 335 0.039
regulation of biosynthetic process GO:0009889 250 0.038
organelle organization GO:0006996 227 0.038
regulation of blood vessel size GO:0050880 2 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
regulation of metabolic process GO:0019222 359 0.038
nucleotide metabolic process GO:0009117 28 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.038
purine containing compound biosynthetic process GO:0072522 20 0.037
negative regulation of biological process GO:0048519 304 0.037
reproductive process GO:0022414 40 0.037
regulation of response to stimulus GO:0048583 269 0.037
single organism intracellular transport GO:1902582 25 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
locomotion GO:0040011 313 0.036
signal transduction GO:0007165 455 0.036
nuclear export GO:0051168 1 0.035
intracellular transport GO:0046907 32 0.035
biosynthetic process GO:0009058 294 0.035
protein stabilization GO:0050821 2 0.035
establishment of localization GO:0051234 244 0.035
Worm
organic substance transport GO:0071702 58 0.035
protein import GO:0017038 3 0.035
regulation of signal transduction GO:0009966 225 0.034
guanosine containing compound metabolic process GO:1901068 4 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
guanosine containing compound catabolic process GO:1901069 2 0.033
actin filament based movement GO:0030048 1 0.033
maintenance of location GO:0051235 4 0.033
rna metabolic process GO:0016070 219 0.033
gtp catabolic process GO:0006184 2 0.033
rna biosynthetic process GO:0032774 181 0.033
regulation of apoptotic process GO:0042981 98 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
negative regulation of apoptotic process GO:0043066 55 0.032
neuron projection morphogenesis GO:0048812 161 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.031
generation of neurons GO:0048699 385 0.031
coenzyme biosynthetic process GO:0009108 2 0.031
regulation of cell communication GO:0010646 232 0.031
transcription dna templated GO:0006351 181 0.031
alpha amino acid metabolic process GO:1901605 3 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
death GO:0016265 121 0.029
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.029
negative regulation of cell communication GO:0010648 96 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
regulation of protein ubiquitination GO:0031396 3 0.029
oxidation reduction process GO:0055114 41 0.028
central nervous system development GO:0007417 387 0.028
cell projection organization GO:0030030 284 0.028
negative regulation of kinase activity GO:0033673 4 0.028
organonitrogen compound biosynthetic process GO:1901566 47 0.028
inorganic cation transmembrane transport GO:0098662 50 0.028
purine nucleoside monophosphate catabolic process GO:0009128 4 0.028
negative regulation of signaling GO:0023057 96 0.028
nucleoside monophosphate catabolic process GO:0009125 4 0.027
cell proliferation GO:0008283 80 0.027
cell part morphogenesis GO:0032990 246 0.027
behavior GO:0007610 74 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
cell migration GO:0016477 237 0.026
positive regulation of catabolic process GO:0009896 4 0.026
cellular component biogenesis GO:0044085 178 0.025
nucleic acid templated transcription GO:0097659 181 0.025
regulation of transcription dna templated GO:0006355 213 0.025
regulation of biological quality GO:0065008 263 0.025
regulation of gene expression GO:0010468 265 0.025
regulation of rna metabolic process GO:0051252 224 0.025
single organism cellular localization GO:1902580 46 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.024
head development GO:0060322 303 0.024
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
cellular ketone metabolic process GO:0042180 11 0.024
protein localization to nucleus GO:0034504 3 0.024
system process GO:0003008 185 0.024
cellular modified amino acid metabolic process GO:0006575 3 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
tissue remodeling GO:0048771 4 0.023
zymogen activation GO:0031638 3 0.023
response to wounding GO:0009611 116 0.022
regulation of signaling GO:0023051 235 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
ribose phosphate metabolic process GO:0019693 27 0.022
regulation of primary metabolic process GO:0080090 311 0.022
cellular amine metabolic process GO:0044106 2 0.022
sulfur compound biosynthetic process GO:0044272 9 0.021
cytoplasm organization GO:0007028 4 0.021
circulatory system process GO:0003013 87 0.021
regulation of developmental process GO:0050793 247 0.021
cellular response to organic substance GO:0071310 105 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
cell aging GO:0007569 2 0.021
response to external stimulus GO:0009605 264 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
cell motility GO:0048870 244 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
negative regulation of cell death GO:0060548 60 0.020
brain development GO:0007420 293 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
digestive tract morphogenesis GO:0048546 231 0.020
blood circulation GO:0008015 87 0.020
multicellular organism growth GO:0035264 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
forebrain development GO:0030900 96 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
forebrain cell migration GO:0021885 1 0.019
nuclear import GO:0051170 3 0.019
ameboidal type cell migration GO:0001667 143 0.019
single organism organelle organization GO:1902589 199 0.019
purine nucleotide metabolic process GO:0006163 27 0.018
lipid storage GO:0019915 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
digestive system development GO:0055123 289 0.018
membrane invagination GO:0010324 1 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
ribose phosphate biosynthetic process GO:0046390 20 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
neuroblast proliferation GO:0007405 2 0.018
phosphorylation GO:0016310 69 0.017
gland development GO:0048732 143 0.017
gtp metabolic process GO:0046039 4 0.017
fin regeneration GO:0031101 51 0.017
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
purine ribonucleotide metabolic process GO:0009150 27 0.017
rna localization GO:0006403 4 0.017
microtubule organizing center organization GO:0031023 1 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
neuron differentiation GO:0030182 353 0.017
endoplasmic reticulum unfolded protein response GO:0030968 2 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
hepaticobiliary system development GO:0061008 98 0.017
gastrulation GO:0007369 208 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
regulation of programmed cell death GO:0043067 101 0.017
atp metabolic process GO:0046034 5 0.017
single organism nuclear import GO:1902593 3 0.017
response to topologically incorrect protein GO:0035966 2 0.017
sensory perception of pain GO:0019233 1 0.017
programmed cell death GO:0012501 119 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
ras protein signal transduction GO:0007265 7 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
ribonucleoside biosynthetic process GO:0042455 2 0.016
regeneration GO:0031099 91 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
protein targeting to nucleus GO:0044744 3 0.016
axon guidance GO:0007411 86 0.016
cell morphogenesis GO:0000902 289 0.016
hemopoiesis GO:0030097 183 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
pole plasm assembly GO:0007315 4 0.016
tissue regeneration GO:0042246 74 0.016
monovalent inorganic cation transport GO:0015672 42 0.016
protein import into nucleus GO:0006606 3 0.016
positive regulation of cellular process GO:0048522 201 0.016
heart development GO:0007507 313 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
nucleotide biosynthetic process GO:0009165 21 0.016
nucleoside phosphate metabolic process GO:0006753 28 0.015
positive regulation of ras protein signal transduction GO:0046579 1 0.015
regulation of mrna processing GO:0050684 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cation transport GO:0006812 81 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
positive regulation of cell cycle GO:0045787 3 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
purine containing compound metabolic process GO:0072521 29 0.015
transmembrane transport GO:0055085 120 0.015
mesenchyme development GO:0060485 127 0.015
axon development GO:0061564 166 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
response to nutrient GO:0007584 3 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
taxis GO:0042330 109 0.014
purine ribonucleoside metabolic process GO:0046128 10 0.014
neuron projection development GO:0031175 180 0.014
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.014
amine metabolic process GO:0009308 2 0.014
b cell activation GO:0042113 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
water homeostasis GO:0030104 4 0.014
vasculature development GO:0001944 278 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
ion homeostasis GO:0050801 41 0.014
generation of precursor metabolites and energy GO:0006091 5 0.014
cellular component morphogenesis GO:0032989 336 0.014
regulation of reproductive process GO:2000241 4 0.014
compound eye development GO:0048749 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of cell death GO:0010941 103 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
purine ribonucleoside biosynthetic process GO:0046129 2 0.014
regulation of cellular component size GO:0032535 30 0.014
homeostatic process GO:0042592 142 0.014
reproduction GO:0000003 40 0.014
Worm
stem cell division GO:0017145 1 0.014
cellular response to radiation GO:0071478 4 0.014
mitochondrion morphogenesis GO:0070584 2 0.014
negative regulation of metabolic process GO:0009892 86 0.014
wound healing GO:0042060 90 0.014
cellular amino acid biosynthetic process GO:0008652 2 0.014
spermatid development GO:0007286 2 0.014
mononuclear cell proliferation GO:0032943 1 0.014
leukocyte proliferation GO:0070661 1 0.014
atp catabolic process GO:0006200 4 0.014
negative regulation of mapk cascade GO:0043409 4 0.013
respiratory electron transport chain GO:0022904 2 0.013
blood vessel development GO:0001568 246 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
protein homooligomerization GO:0051260 3 0.013
membrane repolarization GO:0086009 2 0.013
response to alkaloid GO:0043279 2 0.013
immune system development GO:0002520 191 0.013
localization of cell GO:0051674 244 0.013
cell fate commitment GO:0045165 99 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of cell activation GO:0050865 1 0.013
regulation of anatomical structure size GO:0090066 33 0.013
negative regulation of defense response GO:0031348 2 0.013
central nervous system neuron development GO:0021954 29 0.013
negative regulation of gene expression GO:0010629 65 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
protein localization GO:0008104 40 0.013
defense response to fungus GO:0050832 2 0.013
purine ribonucleotide biosynthetic process GO:0009152 20 0.013
response to unfolded protein GO:0006986 2 0.013
multicellular organismal response to stress GO:0033555 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.012
b cell differentiation GO:0030183 1 0.012
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
response to organic substance GO:0010033 153 0.012
energy derivation by oxidation of organic compounds GO:0015980 5 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
neurotransmitter transport GO:0006836 2 0.012
regulation of photoreceptor cell differentiation GO:0046532 2 0.012
regulation of membrane potential GO:0042391 23 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
response to external biotic stimulus GO:0043207 97 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of protein polymerization GO:0032271 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
nucleoside biosynthetic process GO:0009163 2 0.012
amino acid transport GO:0006865 2 0.012
ribonucleotide metabolic process GO:0009259 27 0.012
hormone biosynthetic process GO:0042446 3 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
synaptic vesicle localization GO:0097479 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
cellular macromolecule localization GO:0070727 21 0.012
axonemal dynein complex assembly GO:0070286 5 0.012
cytoskeleton organization GO:0007010 96 0.012
ear development GO:0043583 127 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
eye development GO:0001654 277 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
digestive tract development GO:0048565 265 0.011
negative regulation of immune response GO:0050777 2 0.011
protein modification process GO:0036211 100 0.011
tube morphogenesis GO:0035239 349 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
establishment of organelle localization GO:0051656 45 0.011
organophosphate metabolic process GO:0019637 37 0.011
centrosome organization GO:0051297 1 0.011
protein polymerization GO:0051258 4 0.011
regulation of cell development GO:0060284 100 0.011
regulation of transporter activity GO:0032409 2 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
peptide metabolic process GO:0006518 1 0.011
nucleoside metabolic process GO:0009116 11 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
neural crest cell development GO:0014032 62 0.011
synaptic transmission GO:0007268 35 0.011
single organism biosynthetic process GO:0044711 71 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of cellular component organization GO:0051128 86 0.011
apoptotic process GO:0006915 116 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
embryonic organ development GO:0048568 381 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
ion transport GO:0006811 114 0.011
carboxylic acid biosynthetic process GO:0046394 12 0.011
nucleic acid metabolic process GO:0090304 244 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
regulation of myotube differentiation GO:0010830 2 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
determination of bilateral symmetry GO:0009855 204 0.011
regulation of gtpase activity GO:0043087 2 0.011
ribonucleoside metabolic process GO:0009119 11 0.011
oxidoreduction coenzyme metabolic process GO:0006733 1 0.011
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.011
apoptotic signaling pathway GO:0097190 23 0.011
regulation of tissue remodeling GO:0034103 2 0.011
cellular response to hypoxia GO:0071456 1 0.011
er nucleus signaling pathway GO:0006984 2 0.011
diterpenoid biosynthetic process GO:0016102 7 0.011
phagocytosis engulfment GO:0006911 1 0.011
cognition GO:0050890 1 0.011
multi organism process GO:0051704 134 0.011
fatty acid biosynthetic process GO:0006633 4 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
sequestering of calcium ion GO:0051208 3 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
spermatid differentiation GO:0048515 2 0.010
regulation of cell shape GO:0008360 1 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
adult behavior GO:0030534 2 0.010
branched chain amino acid metabolic process GO:0009081 1 0.010
regulation of metal ion transport GO:0010959 4 0.010
mechanosensory lateral line system development GO:0048881 49 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
camera type eye development GO:0043010 222 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
striated muscle cell differentiation GO:0051146 129 0.010
negative regulation of catabolic process GO:0009895 3 0.010
regulation of cell growth GO:0001558 29 0.010
cartilage development GO:0051216 96 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010

hccs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.151
disease of anatomical entity DOID:7 0 0.142
Human
nervous system disease DOID:863 0 0.028
Human
inherited metabolic disorder DOID:655 0 0.021
mitochondrial metabolism disease DOID:700 0 0.014
muscle tissue disease DOID:66 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscular disease DOID:0080000 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.010
Human
eye disease DOID:5614 0 0.010
Human
retinal disease DOID:5679 0 0.010
eye and adnexa disease DOID:1492 0 0.010
Human
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010