Danio rerio

0 known processes

hells

helicase, lymphoid-specific

(Aliases: sb:cb65,pasg,cb65,sb:cb749,im:6911667)

hells biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte maturation GO:0001556 4 0.376
meiotic cell cycle process GO:1903046 3 0.343
double strand break repair GO:0006302 3 0.337
negative regulation of histone modification GO:0031057 1 0.330
nitrogen compound metabolic process GO:0006807 319 0.309
Mouse
dna methylation on cytosine GO:0032776 3 0.285
embryo development ending in birth or egg hatching GO:0009792 271 0.262
cellular nitrogen compound metabolic process GO:0034641 290 0.254
Mouse
cellular biosynthetic process GO:0044249 286 0.248
Mouse
organelle organization GO:0006996 227 0.201
Mouse
negative regulation of histone methylation GO:0031061 1 0.199
larval development GO:0002164 2 0.190
mitotic dna integrity checkpoint GO:0044774 4 0.182
dna biosynthetic process GO:0071897 3 0.175
meiosis i GO:0007127 1 0.167
pyrimidine containing compound biosynthetic process GO:0072528 2 0.155
cellular macromolecule biosynthetic process GO:0034645 224 0.148
Mouse
heterocycle metabolic process GO:0046483 290 0.128
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.126
Mouse
reciprocal dna recombination GO:0035825 1 0.124
biosynthetic process GO:0009058 294 0.121
Mouse
cell cycle GO:0007049 93 0.114
cellular aromatic compound metabolic process GO:0006725 295 0.110
Mouse
immune system process GO:0002376 241 0.110
Mouse
double strand break repair via nonhomologous end joining GO:0006303 1 0.105
centrosome organization GO:0051297 1 0.102
dna metabolic process GO:0006259 27 0.101
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.100
Mouse
fertilization GO:0009566 3 0.098
regulation of macromolecule metabolic process GO:0060255 317 0.092
Mouse
nucleic acid metabolic process GO:0090304 244 0.085
Mouse
multicellular organism growth GO:0035264 4 0.079
cell cycle process GO:0022402 53 0.079
chromosome organization GO:0051276 31 0.078
Mouse
mitotic g2 m transition checkpoint GO:0044818 3 0.077
positive regulation of biological process GO:0048518 253 0.076
response to amino acid GO:0043200 2 0.073
regulation of histone h3 k9 methylation GO:0051570 2 0.070
regulation of gene expression GO:0010468 265 0.069
Mouse
meiotic nuclear division GO:0007126 4 0.067
signal transduction GO:0007165 455 0.065
Mouse
macromolecule biosynthetic process GO:0009059 227 0.064
Mouse
organic substance biosynthetic process GO:1901576 289 0.060
Mouse
positive regulation of hydrolase activity GO:0051345 13 0.058
aromatic compound biosynthetic process GO:0019438 217 0.057
Mouse
single organism metabolic process GO:0044710 217 0.056
sister chromatid cohesion GO:0007062 2 0.055
locomotion GO:0040011 313 0.053
single organism organelle organization GO:1902589 199 0.052
Mouse
retina development in camera type eye GO:0060041 146 0.052
cellular nitrogen compound biosynthetic process GO:0044271 218 0.052
Mouse
immune system development GO:0002520 191 0.052
regulation of metabolic process GO:0019222 359 0.052
Mouse
heterocycle biosynthetic process GO:0018130 215 0.051
Mouse
response to chemical GO:0042221 320 0.051
modification dependent protein catabolic process GO:0019941 3 0.051
organic cyclic compound biosynthetic process GO:1901362 223 0.050
Mouse
response to uv GO:0009411 3 0.050
cell cycle g2 m phase transition GO:0044839 4 0.049
reciprocal meiotic recombination GO:0007131 1 0.048
dna catabolic process GO:0006308 1 0.048
organelle fission GO:0048285 23 0.045
dna alkylation GO:0006305 8 0.043
Mouse
mitotic dna damage checkpoint GO:0044773 4 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
Mouse
pronuclear migration GO:0035046 1 0.041
gene expression GO:0010467 252 0.040
Mouse
pyrimidine containing compound metabolic process GO:0072527 3 0.039
regulation of multicellular organism growth GO:0040014 4 0.037
guanosine containing compound metabolic process GO:1901068 4 0.036
multi organism process GO:0051704 134 0.036
negative regulation of cellular process GO:0048523 283 0.036
Mouse
single organism reproductive process GO:0044702 40 0.036
mitotic cell cycle GO:0000278 64 0.035
developmental process involved in reproduction GO:0003006 27 0.035
mitotic g2 dna damage checkpoint GO:0007095 3 0.035
male meiosis GO:0007140 2 0.033
negative regulation of dna metabolic process GO:0051053 4 0.033
positive regulation of histone modification GO:0031058 1 0.033
chromosome organization involved in meiosis GO:0070192 1 0.032
negative regulation of nuclear division GO:0051784 3 0.032
cell division GO:0051301 20 0.032
meiotic chromosome segregation GO:0045132 3 0.032
positive regulation of chromatin modification GO:1903310 1 0.031
microtubule based process GO:0007017 60 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
Mouse
maintenance of dna repeat elements GO:0043570 2 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
Mouse
cellular protein modification process GO:0006464 100 0.030
maintenance of location GO:0051235 4 0.029
multicellular organism reproduction GO:0032504 35 0.029
camera type eye development GO:0043010 222 0.029
negative regulation of chromatin modification GO:1903309 1 0.029
negative regulation of metabolic process GO:0009892 86 0.029
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
immunoglobulin mediated immune response GO:0016064 3 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
chromosome segregation GO:0007059 12 0.027
regulation of protein catabolic process GO:0042176 1 0.027
nuclear division GO:0000280 23 0.027
regulation of meiotic cell cycle GO:0051445 1 0.026
regulation of primary metabolic process GO:0080090 311 0.026
Mouse
positive regulation of catabolic process GO:0009896 4 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.026
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.026
neuron development GO:0048666 262 0.026
negative regulation of chromosome organization GO:2001251 1 0.026
gtp metabolic process GO:0046039 4 0.025
cellular component movement GO:0006928 335 0.025
rna biosynthetic process GO:0032774 181 0.025
Mouse
regulation of response to stimulus GO:0048583 269 0.025
Mouse
response to stress GO:0006950 263 0.025
cytoskeleton organization GO:0007010 96 0.025
cellular response to dna damage stimulus GO:0006974 24 0.025
guanosine containing compound catabolic process GO:1901069 2 0.024
chordate embryonic development GO:0043009 271 0.024
intra s dna damage checkpoint GO:0031573 1 0.024
single organism biosynthetic process GO:0044711 71 0.024
g2 m transition of mitotic cell cycle GO:0000086 4 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
regulation of histone methylation GO:0031060 3 0.023
cellular macromolecule metabolic process GO:0044260 391 0.022
Mouse
response to xenobiotic stimulus GO:0009410 45 0.022
stem cell proliferation GO:0072089 4 0.022
microtubule cytoskeleton organization GO:0000226 33 0.022
dna damage checkpoint GO:0000077 6 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
Mouse
non recombinational repair GO:0000726 2 0.021
mitotic cell cycle process GO:1903047 48 0.021
nuclear migration GO:0007097 3 0.021
cellular protein metabolic process GO:0044267 129 0.021
programmed cell death GO:0012501 119 0.021
Mouse
regulation of cell cycle GO:0051726 52 0.021
protein modification process GO:0036211 100 0.020
b cell activation GO:0042113 2 0.020
negative regulation of biological process GO:0048519 304 0.020
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
Mouse
positive regulation of cell cycle GO:0045787 3 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
negative regulation of mitotic cell cycle GO:0045930 11 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
Mouse
g2 dna damage checkpoint GO:0031572 3 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.019
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.019
Mouse
rna metabolic process GO:0016070 219 0.019
Mouse
small molecule metabolic process GO:0044281 77 0.018
rna dependent dna replication GO:0006278 2 0.018
cellular response to stress GO:0033554 62 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
regulation of chromatin organization GO:1902275 5 0.018
neuroblast proliferation GO:0007405 2 0.018
protein metabolic process GO:0019538 183 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
regulation of dna replication GO:0006275 3 0.018
histone phosphorylation GO:0016572 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
gamete generation GO:0007276 33 0.017
somatic cell dna recombination GO:0016444 1 0.017
single fertilization GO:0007338 3 0.017
regulation of binding GO:0051098 3 0.017
gene silencing by rna GO:0031047 4 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
negative regulation of transcription dna templated GO:0045892 45 0.016
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.016
cell part morphogenesis GO:0032990 246 0.016
phosphorus metabolic process GO:0006793 109 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
death GO:0016265 121 0.016
Mouse
cellular response to chemical stimulus GO:0070887 157 0.016
pancreas development GO:0031016 84 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.015
microtubule polymerization GO:0046785 2 0.015
cell death GO:0008219 121 0.015
Mouse
regulation of transcription dna templated GO:0006355 213 0.015
Mouse
intracellular signal transduction GO:0035556 85 0.015
Mouse
exocrine pancreas development GO:0031017 28 0.015
hemopoiesis GO:0030097 183 0.015
multi organism reproductive process GO:0044703 36 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
heart development GO:0007507 313 0.015
digestive system development GO:0055123 289 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
intrinsic apoptotic signaling pathway GO:0097193 20 0.014
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
transcription dna templated GO:0006351 181 0.014
Mouse
purine nucleotide metabolic process GO:0006163 27 0.014
response to external biotic stimulus GO:0043207 97 0.014
localization of cell GO:0051674 244 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of mitosis GO:0007088 9 0.014
immunoglobulin production GO:0002377 1 0.014
neuron projection development GO:0031175 180 0.014
negative regulation of rna metabolic process GO:0051253 48 0.014
Mouse
generation of neurons GO:0048699 385 0.014
positive regulation of molecular function GO:0044093 33 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
dna repair GO:0006281 6 0.013
mitotic metaphase plate congression GO:0007080 1 0.013
sister chromatid segregation GO:0000819 6 0.013
cell projection organization GO:0030030 284 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
macromolecule modification GO:0043412 111 0.013
Mouse
lateral inhibition GO:0046331 1 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.013
response to organic substance GO:0010033 153 0.013
regulation of ras gtpase activity GO:0032318 2 0.012
mitotic nuclear division GO:0007067 18 0.012
b cell mediated immunity GO:0019724 3 0.012
posttranscriptional gene silencing by rna GO:0035194 3 0.012
response to external stimulus GO:0009605 264 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.012
regulation of protein metabolic process GO:0051246 56 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
cellular response to radiation GO:0071478 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
dna recombination GO:0006310 5 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
gene silencing GO:0016458 4 0.012
Mouse
oxoacid metabolic process GO:0043436 31 0.012
cell fate commitment GO:0045165 99 0.012
peptidyl threonine modification GO:0018210 1 0.012
establishment of localization GO:0051234 244 0.012
macromolecular complex assembly GO:0065003 35 0.012
Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.011
negative regulation of cellular component organization GO:0051129 16 0.011
positive regulation of cellular process GO:0048522 201 0.011
regulation of catalytic activity GO:0050790 55 0.011
amine metabolic process GO:0009308 2 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
Mouse
regulation of stem cell proliferation GO:0072091 2 0.011
meiotic spindle organization GO:0000212 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
Mouse
regulation of rna metabolic process GO:0051252 224 0.011
Mouse
regulation of gtpase activity GO:0043087 2 0.011
deoxyribonucleotide biosynthetic process GO:0009263 1 0.011
regulation of dna recombination GO:0000018 2 0.011
neural retina development GO:0003407 49 0.011
nucleic acid templated transcription GO:0097659 181 0.011
Mouse
negative regulation of catabolic process GO:0009895 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
Mouse
aging GO:0007568 2 0.010
apoptotic signaling pathway GO:0097190 23 0.010
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.010
sex determination GO:0007530 1 0.010
response to alkaloid GO:0043279 2 0.010
chromatin organization GO:0006325 22 0.010
Mouse

hells disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
disease of anatomical entity DOID:7 0 0.024
organ system cancer DOID:0050686 0 0.024
large intestine cancer DOID:5672 0 0.016
gastrointestinal system cancer DOID:3119 0 0.016
intestinal cancer DOID:10155 0 0.016
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010