Danio rerio

113 known processes

her5

hairy-related 5

(Aliases: zgc:136537,her-5,MGC136537)

her5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neural tube patterning GO:0021532 33 0.989
head development GO:0060322 303 0.952
brain development GO:0007420 293 0.950
central nervous system development GO:0007417 387 0.939
anterior posterior pattern specification GO:0009952 152 0.741
hindbrain formation GO:0021576 3 0.732
regionalization GO:0003002 274 0.726
digestive tract morphogenesis GO:0048546 231 0.702
rostrocaudal neural tube patterning GO:0021903 29 0.698
mesodermal cell differentiation GO:0048333 21 0.696
regulation of embryonic development GO:0045995 47 0.692
somite development GO:0061053 96 0.659
Zebrafish
pancreas development GO:0031016 84 0.651
cellular biosynthetic process GO:0044249 286 0.619
Zebrafish Fly
chordate embryonic development GO:0043009 271 0.605
heterocycle biosynthetic process GO:0018130 215 0.581
Zebrafish Fly
gastrulation GO:0007369 208 0.576
metencephalon development GO:0022037 27 0.551
gall bladder development GO:0061010 1 0.545
neural tube development GO:0021915 62 0.532
midbrain hindbrain boundary development GO:0030917 23 0.514
formation of primary germ layer GO:0001704 62 0.461
positive regulation of epithelial cell differentiation GO:0030858 2 0.460
central nervous system neuron differentiation GO:0021953 74 0.444
convergent extension involved in gastrulation GO:0060027 71 0.436
regulation of endodermal cell fate specification GO:0042663 15 0.432
dorsal ventral pattern formation GO:0009953 125 0.428
Fly
heart field specification GO:0003128 1 0.425
endocrine system development GO:0035270 65 0.418
embryonic eye morphogenesis GO:0048048 30 0.415
organic substance biosynthetic process GO:1901576 289 0.405
Zebrafish Fly
mesoderm morphogenesis GO:0048332 51 0.397
mesodermal cell fate specification GO:0007501 12 0.396
response to chemical GO:0042221 320 0.380
spemann organizer formation GO:0060061 10 0.372
cerebellum formation GO:0021588 2 0.372
dorsal ventral axis specification GO:0009950 14 0.359
midbrain development GO:0030901 28 0.347
regulation of gastrulation GO:0010470 24 0.345
regulation of anatomical structure morphogenesis GO:0022603 130 0.338
embryonic organ development GO:0048568 381 0.336
regulation of metabolic process GO:0019222 359 0.335
multi organism process GO:0051704 134 0.333
ectodermal placode development GO:0071696 37 0.332
regulation of cell fate commitment GO:0010453 22 0.319
hepatic duct development GO:0061011 2 0.318
axonogenesis GO:0007409 152 0.311
Zebrafish
spinal cord development GO:0021510 46 0.311
neuron development GO:0048666 262 0.310
Zebrafish Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.308
Zebrafish Fly
embryonic appendage morphogenesis GO:0035113 30 0.300
determination of left right symmetry GO:0007368 179 0.297
embryo development ending in birth or egg hatching GO:0009792 271 0.297
regulation of biosynthetic process GO:0009889 250 0.292
Zebrafish Fly
endodermal cell fate determination GO:0007493 2 0.287
cell projection organization GO:0030030 284 0.282
Zebrafish Fly
blood vessel development GO:0001568 246 0.274
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.273
mesodermal cell fate commitment GO:0001710 14 0.272
aromatic compound biosynthetic process GO:0019438 217 0.265
Zebrafish Fly
eye photoreceptor cell differentiation GO:0001754 45 0.254
Fly
sensory system development GO:0048880 76 0.252
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.249
macromolecule biosynthetic process GO:0009059 227 0.249
Zebrafish Fly
appendage development GO:0048736 80 0.246
gastrulation with mouth forming second GO:0001702 44 0.243
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.239
Zebrafish Fly
cell fate specification GO:0001708 68 0.238
Worm
myelin assembly GO:0032288 1 0.237
negative regulation of gastrulation GO:2000542 11 0.234
convergent extension GO:0060026 118 0.233
mesoderm formation GO:0001707 43 0.232
rhombomere development GO:0021546 19 0.232
endocrine pancreas development GO:0031018 27 0.232
embryonic pectoral fin morphogenesis GO:0035118 24 0.225
embryonic camera type eye development GO:0031076 29 0.210
positive regulation of jun kinase activity GO:0043507 2 0.208
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.208
oligodendrocyte cell fate specification GO:0021778 4 0.204
axon guidance GO:0007411 86 0.199
cell differentiation in spinal cord GO:0021515 40 0.199
forebrain development GO:0030900 96 0.198
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.187
nucleic acid metabolic process GO:0090304 244 0.187
Zebrafish Fly
morphogenesis of an epithelium GO:0002009 333 0.183
stem cell proliferation GO:0072089 4 0.182
Fly
inner ear receptor cell development GO:0060119 20 0.181
cardiogenic plate morphogenesis GO:0003142 1 0.179
organic cyclic compound biosynthetic process GO:1901362 223 0.177
Zebrafish Fly
hindbrain development GO:0030902 91 0.175
cardiocyte differentiation GO:0035051 44 0.174
regulation of stem cell proliferation GO:0072091 2 0.172
Fly
camera type eye development GO:0043010 222 0.172
morphogenesis of embryonic epithelium GO:0016331 30 0.171
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.171
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.168
hindbrain morphogenesis GO:0021575 22 0.168
regulation of developmental process GO:0050793 247 0.167
transcription dna templated GO:0006351 181 0.165
Zebrafish Fly
type b pancreatic cell development GO:0003323 4 0.165
regulation of gene expression GO:0010468 265 0.164
Zebrafish Worm Fly
cell motility GO:0048870 244 0.161
neuron projection morphogenesis GO:0048812 161 0.158
Zebrafish Fly
pectoral fin development GO:0033339 50 0.155
epithelial tube morphogenesis GO:0060562 148 0.155
nephron morphogenesis GO:0072028 2 0.151
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.151
generation of neurons GO:0048699 385 0.149
brain morphogenesis GO:0048854 18 0.148
Fly
embryonic heart tube morphogenesis GO:0003143 108 0.145
embryonic limb morphogenesis GO:0030326 2 0.142
regulation of organ morphogenesis GO:2000027 35 0.142
tube morphogenesis GO:0035239 349 0.140
peptide transport GO:0015833 1 0.139
negative regulation of mesodermal cell fate specification GO:0042662 3 0.139
gene expression GO:0010467 252 0.138
Zebrafish Worm Fly
kupffer s vesicle development GO:0070121 50 0.136
regulation of canonical wnt signaling pathway GO:0060828 34 0.136
digestive system development GO:0055123 289 0.135
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.134
Zebrafish Fly
wnt signaling pathway GO:0016055 80 0.133
forebrain regionalization GO:0021871 4 0.130
axon extension GO:0048675 45 0.129
retina development in camera type eye GO:0060041 146 0.129
determination of heart left right asymmetry GO:0061371 117 0.128
optic placode formation GO:0001743 4 0.126
regulation of wnt signaling pathway GO:0030111 53 0.124
organ formation GO:0048645 17 0.123
Fly
angiogenesis GO:0001525 158 0.122
endodermal cell fate specification GO:0001714 17 0.121
somite specification GO:0001757 12 0.121
Zebrafish
negative regulation of cell fate commitment GO:0010454 13 0.119
limb bud formation GO:0060174 2 0.119
heart morphogenesis GO:0003007 156 0.117
inner ear receptor cell differentiation GO:0060113 29 0.115
segment polarity determination GO:0007367 1 0.114
regulation of reproductive process GO:2000241 4 0.113
positive regulation of muscle organ development GO:0048636 1 0.113
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.112
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.111
embryonic neurocranium morphogenesis GO:0048702 15 0.110
gland development GO:0048732 143 0.110
rhombomere 6 development GO:0021572 4 0.109
floor plate formation GO:0021508 12 0.107
neuroblast proliferation GO:0007405 2 0.106
Fly
axon development GO:0061564 166 0.105
Zebrafish
regulation of nervous system development GO:0051960 90 0.104
cellular nitrogen compound biosynthetic process GO:0044271 218 0.104
Zebrafish Fly
blood vessel morphogenesis GO:0048514 216 0.104
embryonic foregut morphogenesis GO:0048617 1 0.102
neuron projection development GO:0031175 180 0.102
Zebrafish Fly
mesoderm development GO:0007498 88 0.100
Fly
aorta development GO:0035904 4 0.100
cell fate commitment GO:0045165 99 0.100
Worm Fly
regulation of stem cell differentiation GO:2000736 4 0.099
ectodermal placode formation GO:0060788 26 0.098
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.098
embryonic heart tube development GO:0035050 133 0.097
digestive tract development GO:0048565 265 0.096
bmp signaling pathway involved in heart development GO:0061312 15 0.096
cellular component morphogenesis GO:0032989 336 0.094
Zebrafish Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.094
regulation of response to stimulus GO:0048583 269 0.090
Fly
nitrogen compound metabolic process GO:0006807 319 0.090
Zebrafish Fly
eye morphogenesis GO:0048592 144 0.089
Fly
cardiac cell fate commitment GO:0060911 1 0.089
mediolateral intercalation GO:0060031 3 0.088
dorsal convergence GO:0060030 14 0.088
negative regulation of cell differentiation GO:0045596 46 0.088
endoderm development GO:0007492 49 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.088
Zebrafish Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.087
Zebrafish Fly
regeneration GO:0031099 91 0.087
locomotion GO:0040011 313 0.086
Fly
multicellular organism growth GO:0035264 4 0.085
heart looping GO:0001947 94 0.085
mechanoreceptor differentiation GO:0042490 37 0.085
regulation of axon extension GO:0030516 24 0.084
negative regulation of endodermal cell differentiation GO:1903225 8 0.082
positive regulation of nucleic acid templated transcription GO:1903508 57 0.081
liver development GO:0001889 96 0.081
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.081
post embryonic morphogenesis GO:0009886 4 0.080
regulation of multicellular organismal process GO:0051239 277 0.080
ectoderm development GO:0007398 9 0.080
optic placode formation involved in camera type eye formation GO:0046619 3 0.078
negative regulation of endodermal cell fate specification GO:0042664 8 0.078
stem cell division GO:0017145 1 0.077
cardiac muscle tissue development GO:0048738 48 0.077
eye development GO:0001654 277 0.077
Zebrafish Fly
inner ear morphogenesis GO:0042472 63 0.077
spinal cord anterior posterior patterning GO:0021512 1 0.077
ventral spinal cord development GO:0021517 35 0.076
rhombomere morphogenesis GO:0021593 17 0.075
cell morphogenesis GO:0000902 289 0.074
Zebrafish Fly
neuron projection extension GO:1990138 45 0.072
thrombocyte differentiation GO:0002574 4 0.072
negative regulation of cell fate specification GO:0009996 11 0.072
positive regulation of gene expression GO:0010628 71 0.071
appendage morphogenesis GO:0035107 56 0.070
negative regulation of nucleic acid templated transcription GO:1903507 45 0.070
Zebrafish Fly
morphogenesis of an epithelial sheet GO:0002011 49 0.070
muscle organ development GO:0007517 101 0.069
adenohypophysis development GO:0021984 15 0.068
positive regulation of rna metabolic process GO:0051254 59 0.068
foregut morphogenesis GO:0007440 4 0.068
cerebellum development GO:0021549 17 0.067
endoderm formation GO:0001706 29 0.066
skeletal muscle organ development GO:0060538 78 0.066
cell proliferation GO:0008283 80 0.066
Fly
growth GO:0040007 174 0.065
ear morphogenesis GO:0042471 64 0.065
homeostatic process GO:0042592 142 0.065
oocyte maturation GO:0001556 4 0.064
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.064
regulation of macromolecule biosynthetic process GO:0010556 225 0.064
Zebrafish Fly
glandular epithelial cell differentiation GO:0002067 9 0.064
nephron tubule morphogenesis GO:0072078 1 0.063
neural retina development GO:0003407 49 0.063
pons development GO:0021548 11 0.063
somitogenesis GO:0001756 87 0.062
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.062
Zebrafish Fly
photoreceptor cell differentiation GO:0046530 55 0.062
Fly
striated muscle tissue development GO:0014706 110 0.062
positive regulation of cellular biosynthetic process GO:0031328 68 0.062
apoptotic process involved in morphogenesis GO:0060561 2 0.062
regulation of anterior head development GO:2000742 2 0.062
cell migration involved in gastrulation GO:0042074 79 0.061
biosynthetic process GO:0009058 294 0.061
Zebrafish Fly
regulation of rna biosynthetic process GO:2001141 213 0.061
Zebrafish Fly
cellular component movement GO:0006928 335 0.060
mesenchymal cell proliferation GO:0010463 1 0.060
rhombomere 5 morphogenesis GO:0021664 1 0.060
developmental cell growth GO:0048588 52 0.060
epithelial cell differentiation GO:0030855 116 0.059
Worm
mesodermal cell migration GO:0008078 12 0.059
regulation of cell fate specification GO:0042659 20 0.058
negative regulation of wnt signaling pathway GO:0030178 30 0.058
positive regulation of rna biosynthetic process GO:1902680 57 0.058
rhombomere 5 development GO:0021571 4 0.057
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.057
swim bladder development GO:0048794 19 0.056
dorsal aorta development GO:0035907 4 0.056
ventral midline development GO:0007418 13 0.056
localization of cell GO:0051674 244 0.056
behavior GO:0007610 74 0.056
Fly
response to fibroblast growth factor GO:0071774 22 0.055
epiboly GO:0090504 41 0.055
regulation of heart morphogenesis GO:2000826 17 0.055
aorta morphogenesis GO:0035909 3 0.054
embryonic skeletal system development GO:0048706 97 0.054
pituitary gland development GO:0021983 16 0.054
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.054
regulation of multicellular organism growth GO:0040014 4 0.053
neuron projection guidance GO:0097485 86 0.053
embryonic organ morphogenesis GO:0048562 274 0.053
rhombomere 4 development GO:0021570 5 0.052
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.051
oligodendrocyte differentiation GO:0048709 23 0.051
negative regulation of rna biosynthetic process GO:1902679 45 0.051
Zebrafish Fly
transport GO:0006810 220 0.051
diencephalon development GO:0021536 58 0.050
Zebrafish
axis elongation GO:0003401 31 0.050
taxis GO:0042330 109 0.050
regulation of endodermal cell differentiation GO:1903224 15 0.050
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.050
fin regeneration GO:0031101 51 0.050
proepicardium development GO:0003342 4 0.049
limbic system development GO:0021761 16 0.049
negative regulation of cellular metabolic process GO:0031324 77 0.048
Zebrafish Fly
forebrain anterior posterior pattern specification GO:0021797 3 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.048
hepaticobiliary system development GO:0061008 98 0.047
cell cell signaling GO:0007267 52 0.046
regulation of cell morphogenesis GO:0022604 42 0.046
regulation of gtp catabolic process GO:0033124 2 0.045
nephron epithelium morphogenesis GO:0072088 1 0.045
astrocyte differentiation GO:0048708 1 0.045
positive regulation of muscle tissue development GO:1901863 1 0.045
cell migration GO:0016477 237 0.045
regulation of neuron differentiation GO:0045664 56 0.045
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.044
ameboidal type cell migration GO:0001667 143 0.044
developmental induction GO:0031128 10 0.044
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.044
regulation of neurotransmitter transport GO:0051588 1 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
Zebrafish Fly
bmp signaling pathway GO:0030509 52 0.043
periodic partitioning GO:0007365 1 0.043
developmental process involved in reproduction GO:0003006 27 0.042
Worm
photoreceptor cell fate commitment GO:0046552 1 0.042
single organism transport GO:0044765 206 0.042
establishment of localization GO:0051234 244 0.042
negative regulation of reproductive process GO:2000242 3 0.041
cardiac chamber formation GO:0003207 4 0.041
embryonic camera type eye morphogenesis GO:0048596 19 0.041
endocardium formation GO:0060214 1 0.040
negative regulation of cellular process GO:0048523 283 0.040
immune system process GO:0002376 241 0.040
ectodermal placode morphogenesis GO:0071697 32 0.039
positive regulation of developmental process GO:0051094 50 0.039
Fly
tissue regeneration GO:0042246 74 0.039
heart development GO:0007507 313 0.039
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.039
notochord development GO:0030903 54 0.039
embryonic digestive tract morphogenesis GO:0048557 3 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.038
hepatocyte proliferation GO:0072574 2 0.038
type b pancreatic cell differentiation GO:0003309 8 0.037
artery development GO:0060840 22 0.037
floor plate morphogenesis GO:0033505 12 0.037
embryonic skeletal system morphogenesis GO:0048704 93 0.037
wnt signaling pathway involved in heart development GO:0003306 5 0.036
heart formation GO:0060914 13 0.036
positive regulation of metabolic process GO:0009893 108 0.036
developmental growth involved in morphogenesis GO:0060560 86 0.036
dorsal spinal cord development GO:0021516 1 0.036
regulation of protein catabolic process GO:0042176 1 0.035
regulation of extent of cell growth GO:0061387 29 0.035
spinal cord patterning GO:0021511 6 0.035
cell part morphogenesis GO:0032990 246 0.035
Zebrafish Fly
endodermal cell fate commitment GO:0001711 18 0.035
response to stress GO:0006950 263 0.035
Fly
compound eye development GO:0048749 2 0.035
Fly
telencephalon development GO:0021537 14 0.035
glial cell fate specification GO:0021780 4 0.035
negative regulation of cell development GO:0010721 26 0.035
cellular macromolecule metabolic process GO:0044260 391 0.035
otic vesicle formation GO:0030916 27 0.035
regulation of non canonical wnt signaling pathway GO:2000050 7 0.034
enteroendocrine cell differentiation GO:0035883 9 0.034
neuron differentiation GO:0030182 353 0.034
Zebrafish Fly
regulation of cell differentiation GO:0045595 142 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
positive regulation of macromolecule metabolic process GO:0010604 93 0.034
sexual reproduction GO:0019953 36 0.034
kidney development GO:0001822 92 0.034
embryonic camera type eye formation GO:0060900 10 0.034
stem cell differentiation GO:0048863 117 0.034
axis specification GO:0009798 43 0.033
reproductive process GO:0022414 40 0.032
Worm
camera type eye photoreceptor cell differentiation GO:0060219 19 0.032
regulation of mesodermal cell fate specification GO:0042661 9 0.032
lateral line development GO:0048882 66 0.032
glomerulus development GO:0032835 27 0.031
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.031
negative regulation of mitosis GO:0045839 3 0.031
endodermal cell differentiation GO:0035987 19 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
Zebrafish Fly
non canonical wnt signaling pathway GO:0035567 13 0.031
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.031
neural plate development GO:0001840 10 0.030
neuromast development GO:0048884 46 0.030
muscle tissue development GO:0060537 110 0.030
camera type eye morphogenesis GO:0048593 108 0.029
embryonic cranial skeleton morphogenesis GO:0048701 90 0.029
negative regulation of transcription dna templated GO:0045892 45 0.029
Zebrafish Fly
pharyngeal system development GO:0060037 18 0.029
negative regulation of rna metabolic process GO:0051253 48 0.029
Zebrafish Fly
epidermal cell differentiation GO:0009913 36 0.029
Worm
pectoral fin morphogenesis GO:0035138 29 0.029
neural crest cell differentiation GO:0014033 72 0.028
negative regulation of gene expression GO:0010629 65 0.028
Zebrafish Worm Fly
specification of organ identity GO:0010092 2 0.028
pronephros development GO:0048793 69 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
Zebrafish Fly
negative regulation of embryonic development GO:0045992 11 0.028
regulation of cellular component organization GO:0051128 86 0.028
otic placode formation GO:0043049 23 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.027
Zebrafish Fly
hair cell differentiation GO:0035315 32 0.027
reflex GO:0060004 2 0.027
cell division GO:0051301 20 0.027
fatty acid biosynthetic process GO:0006633 4 0.027
regulation of jun kinase activity GO:0043506 3 0.027
stem cell development GO:0048864 82 0.027
septum transversum development GO:0003343 4 0.027
developmental maturation GO:0021700 34 0.027
negative regulation of metabolic process GO:0009892 86 0.027
Zebrafish Worm Fly
mitotic nuclear division GO:0007067 18 0.027
rhombomere formation GO:0021594 12 0.027
floor plate development GO:0033504 15 0.027
motor neuron axon guidance GO:0008045 23 0.027
regulation of signaling GO:0023051 235 0.026
regulation of biological quality GO:0065008 263 0.026
epithelium regeneration GO:1990399 14 0.026
rna biosynthetic process GO:0032774 181 0.026
Zebrafish Fly
regulation of growth GO:0040008 42 0.026
regulation of neurogenesis GO:0050767 87 0.025
neural plate morphogenesis GO:0001839 7 0.025
cell cell recognition GO:0009988 1 0.025
defense response GO:0006952 47 0.024
tube formation GO:0035148 25 0.024
regulation of axonogenesis GO:0050770 32 0.024
negative regulation of stem cell differentiation GO:2000737 2 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
primary neural tube formation GO:0014020 1 0.024
developmental growth GO:0048589 166 0.024
anterior head development GO:0097065 2 0.024
negative regulation of developmental process GO:0051093 65 0.024
cardioblast migration GO:0003260 7 0.024
zymogen activation GO:0031638 3 0.023
organelle localization GO:0051640 49 0.023
sensory organ development GO:0007423 393 0.023
Zebrafish Fly
developmental programmed cell death GO:0010623 4 0.023
anterior commissure morphogenesis GO:0021960 3 0.022
canonical wnt signaling pathway GO:0060070 48 0.022
organonitrogen compound biosynthetic process GO:1901566 47 0.022
epithelial cell development GO:0002064 42 0.022
positive regulation of cellular process GO:0048522 201 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
macromolecule catabolic process GO:0009057 15 0.022
regulation of transcription dna templated GO:0006355 213 0.022
Zebrafish Fly
chemotaxis GO:0006935 104 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.021
multi organism reproductive process GO:0044703 36 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
pronephric glomerulus development GO:0039021 13 0.021
cell cell signaling involved in cell fate commitment GO:0045168 12 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
Zebrafish Fly
anatomical structure arrangement GO:0048532 2 0.021
determination of bilateral symmetry GO:0009855 204 0.020
otic vesicle morphogenesis GO:0071600 34 0.020
common bile duct development GO:0061009 13 0.020
sensory organ morphogenesis GO:0090596 200 0.020
Fly
organonitrogen compound metabolic process GO:1901564 74 0.020
gtp catabolic process GO:0006184 2 0.020
retinal pigment epithelium development GO:0003406 8 0.020
positive regulation of leukocyte differentiation GO:1902107 1 0.020
thyroid gland development GO:0030878 12 0.020
single organism organelle organization GO:1902589 199 0.020
bmp signaling pathway involved in heart jogging GO:0003303 14 0.020
kidney morphogenesis GO:0060993 15 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
Fly
cell projection morphogenesis GO:0048858 244 0.020
Zebrafish Fly
vasculature development GO:0001944 278 0.020
cilium morphogenesis GO:0060271 85 0.020
single organism reproductive process GO:0044702 40 0.019
small molecule metabolic process GO:0044281 77 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.019
endocardium morphogenesis GO:0003160 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
pancreatic a cell development GO:0003322 2 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
Zebrafish Worm Fly
androgen biosynthetic process GO:0006702 1 0.019
heterocycle metabolic process GO:0046483 290 0.019
Zebrafish Fly
regulation of cell communication GO:0010646 232 0.019
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.019
single organism metabolic process GO:0044710 217 0.019
embryonic pattern specification GO:0009880 44 0.018
Zebrafish
cerebellum morphogenesis GO:0021587 10 0.018
bone remodeling GO:0046849 2 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.018
embryonic hemopoiesis GO:0035162 53 0.018
locus ceruleus development GO:0021703 3 0.018
regulation of cardiac chamber morphogenesis GO:1901219 2 0.018
thalamus development GO:0021794 6 0.018
Zebrafish
disruption of cells of other organism GO:0044364 1 0.018
vestibular receptor cell differentiation GO:0060114 3 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
cell cycle GO:0007049 93 0.017
facial nucleus development GO:0021754 7 0.017
signal transduction GO:0007165 455 0.017
Zebrafish
cellular hormone metabolic process GO:0034754 19 0.017
cellular protein catabolic process GO:0044257 4 0.017
regulation of inner ear receptor cell differentiation GO:2000980 1 0.017
regulation of neural retina development GO:0061074 2 0.017
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.017
establishment of localization in cell GO:0051649 77 0.017
otolith development GO:0048840 32 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.017
single organism localization GO:1902578 225 0.017
androgen metabolic process GO:0008209 2 0.017
convergent extension involved in axis elongation GO:0060028 26 0.017
striated muscle cell differentiation GO:0051146 129 0.017
branching morphogenesis of an epithelial tube GO:0048754 15 0.017
convergent extension involved in organogenesis GO:0060029 10 0.016
connective tissue development GO:0061448 99 0.016
axial mesodermal cell fate specification GO:0048327 3 0.016
fourth ventricle development GO:0021592 8 0.016
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.016
organic substance transport GO:0071702 58 0.016
response to wounding GO:0009611 116 0.016
specification of symmetry GO:0009799 204 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016

her5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.190
bone disease DOID:0080001 0 0.190
disease of anatomical entity DOID:7 0 0.190
musculoskeletal system disease DOID:17 0 0.190
connective tissue disease DOID:65 0 0.190
dysostosis DOID:1934 0 0.028
nervous system disease DOID:863 0 0.019