Danio rerio

0 known processes

hig1

hypoxia induced gene 1

(Aliases: wu:fb57h02,cb659,zgc:77692)

hig1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.204
mitochondrial transport GO:0006839 2 0.199
mitochondrion organization GO:0007005 4 0.173
embryo development ending in birth or egg hatching GO:0009792 271 0.152
organelle organization GO:0006996 227 0.140
organic substance biosynthetic process GO:1901576 289 0.126
oxidation reduction process GO:0055114 41 0.119
signal transduction GO:0007165 455 0.102
larval development GO:0002164 2 0.098
single organism metabolic process GO:0044710 217 0.085
regulation of response to stimulus GO:0048583 269 0.084
microtubule organizing center organization GO:0031023 1 0.080
cellular respiration GO:0045333 3 0.065
establishment of protein localization to organelle GO:0072594 4 0.064
alpha amino acid metabolic process GO:1901605 3 0.060
transmembrane transport GO:0055085 120 0.058
establishment of localization GO:0051234 244 0.054
nitrogen compound metabolic process GO:0006807 319 0.054
centrosome organization GO:0051297 1 0.053
regulation of p38mapk cascade GO:1900744 1 0.052
er nucleus signaling pathway GO:0006984 2 0.052
regulation of signal transduction GO:0009966 225 0.052
regulation of muscle contraction GO:0006937 3 0.051
negative regulation of protein phosphorylation GO:0001933 4 0.047
response to topologically incorrect protein GO:0035966 2 0.046
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.046
positive regulation of metabolic process GO:0009893 108 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.045
muscle structure development GO:0061061 196 0.044
cellular macromolecule metabolic process GO:0044260 391 0.042
regulation of nucleoside metabolic process GO:0009118 2 0.041
single organism organelle organization GO:1902589 199 0.040
p38mapk cascade GO:0038066 1 0.039
sulfur compound biosynthetic process GO:0044272 9 0.039
multicellular organism growth GO:0035264 4 0.039
heterocycle metabolic process GO:0046483 290 0.039
organic cyclic compound metabolic process GO:1901360 301 0.038
cell death GO:0008219 121 0.038
Human
response to chemical GO:0042221 320 0.038
regulation of tube size GO:0035150 2 0.038
nucleocytoplasmic transport GO:0006913 4 0.038
single organism localization GO:1902578 225 0.038
nucleic acid templated transcription GO:0097659 181 0.037
death GO:0016265 121 0.036
Human
response to transition metal nanoparticle GO:1990267 28 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.035
cellular aromatic compound metabolic process GO:0006725 295 0.035
single organism biosynthetic process GO:0044711 71 0.035
centrosome cycle GO:0007098 1 0.034
regulation of nucleotide catabolic process GO:0030811 2 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.034
macromolecular complex subunit organization GO:0043933 74 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.032
maintenance of location GO:0051235 4 0.032
transcription dna templated GO:0006351 181 0.031
anion transport GO:0006820 38 0.030
nucleobase containing compound transport GO:0015931 2 0.030
regulation of striated muscle contraction GO:0006942 2 0.030
regulation of multicellular organism growth GO:0040014 4 0.029
response to stress GO:0006950 263 0.029
regulation of cell projection assembly GO:0060491 4 0.029
somite development GO:0061053 96 0.029
vasculature development GO:0001944 278 0.029
regulation of blood vessel size GO:0050880 2 0.028
gtp metabolic process GO:0046039 4 0.028
rna metabolic process GO:0016070 219 0.028
cytoskeleton organization GO:0007010 96 0.028
positive regulation of nucleotide catabolic process GO:0030813 1 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
rna biosynthetic process GO:0032774 181 0.028
multi organism process GO:0051704 134 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
cell projection morphogenesis GO:0048858 244 0.027
positive regulation of nucleoside metabolic process GO:0045979 1 0.027
positive regulation of catabolic process GO:0009896 4 0.027
gtp catabolic process GO:0006184 2 0.026
response to unfolded protein GO:0006986 2 0.026
regulation of primary metabolic process GO:0080090 311 0.026
transport GO:0006810 220 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
cellular component biogenesis GO:0044085 178 0.025
activation of mapkkk activity GO:0000185 1 0.025
oxoacid metabolic process GO:0043436 31 0.025
nuclear transport GO:0051169 4 0.025
regulation of signaling GO:0023051 235 0.025
cofactor biosynthetic process GO:0051188 10 0.025
regulation of apoptotic process GO:0042981 98 0.025
Human
positive regulation of transport GO:0051050 2 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
regulation of reproductive process GO:2000241 4 0.024
cellular response to topologically incorrect protein GO:0035967 2 0.024
regulation of developmental process GO:0050793 247 0.024
female gonad development GO:0008585 4 0.024
establishment of localization in cell GO:0051649 77 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
organic acid metabolic process GO:0006082 31 0.024
negative regulation of kinase activity GO:0033673 4 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
positive regulation of biological process GO:0048518 253 0.024
endoplasmic reticulum unfolded protein response GO:0030968 2 0.023
regulation of cell substrate adhesion GO:0010810 1 0.023
cellular response to radiation GO:0071478 4 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
zymogen activation GO:0031638 3 0.023
regulation of molecular function GO:0065009 70 0.023
blood circulation GO:0008015 87 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.022
er to golgi vesicle mediated transport GO:0006888 1 0.022
regulation of filopodium assembly GO:0051489 2 0.022
intracellular transport GO:0046907 32 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
coenzyme biosynthetic process GO:0009108 2 0.022
tissue remodeling GO:0048771 4 0.022
immune system process GO:0002376 241 0.022
female sex differentiation GO:0046660 4 0.022
reproductive process GO:0022414 40 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
regeneration GO:0031099 91 0.021
myofibril assembly GO:0030239 48 0.021
protein import into nucleus GO:0006606 3 0.021
oocyte maturation GO:0001556 4 0.021
cellular response to unfolded protein GO:0034620 2 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
regulation of gtpase activity GO:0043087 2 0.021
spermatid differentiation GO:0048515 2 0.021
cellular amine metabolic process GO:0044106 2 0.021
spermatid development GO:0007286 2 0.021
regulation of metal ion transport GO:0010959 4 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.020
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.020
nuclear import GO:0051170 3 0.020
regulation of programmed cell death GO:0043067 101 0.019
Human
blood vessel development GO:0001568 246 0.019
macromolecule modification GO:0043412 111 0.019
phosphorus metabolic process GO:0006793 109 0.019
actomyosin structure organization GO:0031032 53 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
positive regulation of jnk cascade GO:0046330 3 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of biological quality GO:0065008 263 0.019
blood vessel morphogenesis GO:0048514 216 0.019
ion transport GO:0006811 114 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.018
segmentation GO:0035282 97 0.018
gene expression GO:0010467 252 0.018
calcium mediated signaling GO:0019722 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
phagocytosis GO:0006909 3 0.018
hemopoiesis GO:0030097 183 0.018
protein metabolic process GO:0019538 183 0.018
protein import GO:0017038 3 0.018
circulatory system process GO:0003013 87 0.018
cellular component morphogenesis GO:0032989 336 0.018
programmed cell death GO:0012501 119 0.018
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
response to external stimulus GO:0009605 264 0.017
organic substance transport GO:0071702 58 0.017
regulation of metabolic process GO:0019222 359 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
regulation of cardiac muscle contraction GO:0055117 2 0.017
somitogenesis GO:0001756 87 0.017
cellular biosynthetic process GO:0044249 286 0.017
protein modification process GO:0036211 100 0.017
positive regulation of stress activated mapk cascade GO:0032874 3 0.017
organic anion transport GO:0015711 15 0.017
thioester metabolic process GO:0035383 1 0.016
intracellular signal transduction GO:0035556 85 0.016
actin cytoskeleton organization GO:0030036 63 0.016
striated muscle cell development GO:0055002 108 0.016
single organism nuclear import GO:1902593 3 0.016
atp catabolic process GO:0006200 4 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
response to uv GO:0009411 3 0.016
small molecule metabolic process GO:0044281 77 0.016
ovulation cycle process GO:0022602 2 0.016
positive regulation of developmental process GO:0051094 50 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
response to methylmercury GO:0051597 11 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of cytokine production GO:0001817 3 0.015
cellular protein metabolic process GO:0044267 129 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
positive regulation of cellular process GO:0048522 201 0.015
positive regulation of cell cycle GO:0045787 3 0.015
neuron projection development GO:0031175 180 0.015
regulation of sodium ion transport GO:0002028 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of organelle assembly GO:1902115 4 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
regulation of ph GO:0006885 3 0.015
system process GO:0003008 185 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
regulation of gene expression GO:0010468 265 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
acyl coa metabolic process GO:0006637 1 0.014
regulation of cell shape GO:0008360 1 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cellular protein modification process GO:0006464 100 0.014
developmental growth GO:0048589 166 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
phosphorylation GO:0016310 69 0.014
single organism transport GO:0044765 206 0.014
water homeostasis GO:0030104 4 0.014
protein complex subunit organization GO:0071822 46 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
response to organic substance GO:0010033 153 0.014
biosynthetic process GO:0009058 294 0.014
mitochondrion morphogenesis GO:0070584 2 0.014
positive regulation of molecular function GO:0044093 33 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
apoptotic process GO:0006915 116 0.014
Human
regulation of protein catabolic process GO:0042176 1 0.014
regulation of protein metabolic process GO:0051246 56 0.014
regulation of protein polymerization GO:0032271 2 0.014
skeletal system development GO:0001501 181 0.014
regulation of protein transport GO:0051223 3 0.013
cell aging GO:0007569 2 0.013
protein homooligomerization GO:0051260 3 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
multicellular organismal response to stress GO:0033555 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
single organism cellular localization GO:1902580 46 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
cell projection organization GO:0030030 284 0.013
response to nutrient GO:0007584 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
cell matrix adhesion GO:0007160 4 0.013
lipid storage GO:0019915 1 0.013
neuron development GO:0048666 262 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
adult behavior GO:0030534 2 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of binding GO:0051098 3 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
cellular component disassembly GO:0022411 1 0.012
cellular localization GO:0051641 97 0.012
glial cell migration GO:0008347 3 0.012
stem cell maintenance GO:0019827 4 0.012
protein polymerization GO:0051258 4 0.012
microtubule based process GO:0007017 60 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.012
lamellipodium organization GO:0097581 1 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
cofactor metabolic process GO:0051186 15 0.012
ovulation cycle GO:0042698 2 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
response to drug GO:0042493 3 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
growth GO:0040007 174 0.012
single organism intracellular transport GO:1902582 25 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
neuron projection morphogenesis GO:0048812 161 0.012
localization within membrane GO:0051668 1 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
pyruvate metabolic process GO:0006090 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.011
negative regulation of signaling GO:0023057 96 0.011
amine metabolic process GO:0009308 2 0.011
nucleic acid metabolic process GO:0090304 244 0.011
protein localization to plasma membrane GO:0072659 1 0.011
cellular response to stress GO:0033554 62 0.011
carboxylic acid biosynthetic process GO:0046394 12 0.011
organic acid transport GO:0015849 9 0.011
immune system development GO:0002520 191 0.011
b cell activation GO:0042113 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
response to vitamin GO:0033273 3 0.011
ras protein signal transduction GO:0007265 7 0.011
muscle cell differentiation GO:0042692 139 0.011
response to amino acid GO:0043200 2 0.011
regulation of transporter activity GO:0032409 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
meiotic nuclear division GO:0007126 4 0.011
cell substrate adhesion GO:0031589 4 0.011
regulation of cell death GO:0010941 103 0.011
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
cellular component movement GO:0006928 335 0.011
cell part morphogenesis GO:0032990 246 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
negative regulation of immune response GO:0050777 2 0.011
secondary metabolic process GO:0019748 3 0.011
muscle cell development GO:0055001 115 0.011
protein localization GO:0008104 40 0.011
regionalization GO:0003002 274 0.011
response to alkaloid GO:0043279 2 0.011
cellular component assembly GO:0022607 170 0.011
negative regulation of heart contraction GO:0045822 2 0.011
regulation of intracellular ph GO:0051453 1 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
regulation of catalytic activity GO:0050790 55 0.011
meiotic chromosome segregation GO:0045132 3 0.011
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of heart contraction GO:0008016 32 0.010
microtubule polymerization or depolymerization GO:0031109 3 0.010
long chain fatty acid metabolic process GO:0001676 1 0.010
compound eye development GO:0048749 2 0.010
phagocytosis engulfment GO:0006911 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
regulation of protein targeting GO:1903533 2 0.010
membrane invagination GO:0010324 1 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
positive regulation of cell substrate adhesion GO:0010811 1 0.010
positive regulation of catalytic activity GO:0043085 25 0.010
heart contraction GO:0060047 71 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
energy reserve metabolic process GO:0006112 2 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010

hig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
sensory system disease DOID:0050155 0 0.016
eye disease DOID:5614 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010