Danio rerio

20 known processes

hmcn1

hemicentin 1

(Aliases: si:ch211-169j21.3)

hmcn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonal defasciculation GO:0007414 2 0.861
embryo development ending in birth or egg hatching GO:0009792 271 0.738
negative regulation of biological process GO:0048519 304 0.708
cell substrate adhesion GO:0031589 4 0.652
medial fin development GO:0033338 16 0.650
Zebrafish
larval development GO:0002164 2 0.624
fin development GO:0033333 77 0.456
negative regulation of signal transduction GO:0009968 94 0.427
embryonic organ development GO:0048568 381 0.415
fin morphogenesis GO:0033334 53 0.407
sensory perception of chemical stimulus GO:0007606 3 0.390
cell matrix adhesion GO:0007160 4 0.356
heart development GO:0007507 313 0.349
Zebrafish
regulation of signaling GO:0023051 235 0.284
organic cyclic compound biosynthetic process GO:1901362 223 0.254
extracellular structure organization GO:0043062 27 0.248
embryonic medial fin morphogenesis GO:0035122 6 0.232
Zebrafish
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.210
negative regulation of response to stimulus GO:0048585 104 0.199
signal transduction GO:0007165 455 0.199
regulation of transmembrane transport GO:0034762 18 0.198
locomotion GO:0040011 313 0.195
Zebrafish Worm
embryonic organ morphogenesis GO:0048562 274 0.190
heterocycle metabolic process GO:0046483 290 0.189
maintenance of location GO:0051235 4 0.187
establishment of localization GO:0051234 244 0.187
regulation of multicellular organism growth GO:0040014 4 0.179
regulation of response to stimulus GO:0048583 269 0.177
cell motility GO:0048870 244 0.176
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.170
regulation of gene expression GO:0010468 265 0.170
nucleic acid templated transcription GO:0097659 181 0.167
negative regulation of cellular process GO:0048523 283 0.162
transcription from rna polymerase ii promoter GO:0006366 80 0.153
basement membrane organization GO:0071711 5 0.148
caudal fin development GO:0033336 9 0.138
muscle attachment GO:0016203 9 0.138
cell surface receptor signaling pathway GO:0007166 325 0.136
regulation of signal transduction GO:0009966 225 0.135
muscle structure development GO:0061061 196 0.127
sensory perception of smell GO:0007608 2 0.127
nucleic acid metabolic process GO:0090304 244 0.126
response to stress GO:0006950 263 0.122
cellular aromatic compound metabolic process GO:0006725 295 0.120
tube morphogenesis GO:0035239 349 0.119
specification of symmetry GO:0009799 204 0.118
enzyme linked receptor protein signaling pathway GO:0007167 106 0.118
cellular response to organic substance GO:0071310 105 0.115
nucleocytoplasmic transport GO:0006913 4 0.114
regulation of protein catabolic process GO:0042176 1 0.113
multicellular organism growth GO:0035264 4 0.112
regulation of locomotion GO:0040012 55 0.110
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.108
aromatic compound biosynthetic process GO:0019438 217 0.106
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.102
positive regulation of catabolic process GO:0009896 4 0.098
aging GO:0007568 2 0.097
cellular protein catabolic process GO:0044257 4 0.096
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.094
cognition GO:0050890 1 0.094
medial fin morphogenesis GO:0035141 14 0.092
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.092
rna metabolic process GO:0016070 219 0.088
regulation of rna biosynthetic process GO:2001141 213 0.088
regionalization GO:0003002 274 0.087
biological adhesion GO:0022610 40 0.085
caudal fin morphogenesis GO:0035143 7 0.085
transcription dna templated GO:0006351 181 0.084
chordate embryonic development GO:0043009 271 0.083
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.082
system process GO:0003008 185 0.082
single organism transport GO:0044765 206 0.080
regulation of macromolecule biosynthetic process GO:0010556 225 0.079
appendage development GO:0048736 80 0.079
regulation of cell migration GO:0030334 40 0.075
neuron development GO:0048666 262 0.074
response to organic substance GO:0010033 153 0.074
regulation of binding GO:0051098 3 0.073
negative regulation of cell communication GO:0010648 96 0.071
regulation of establishment of protein localization GO:0070201 4 0.070
nuclear transport GO:0051169 4 0.068
single organism localization GO:1902578 225 0.068
wound healing GO:0042060 90 0.067
digestive system development GO:0055123 289 0.066
cellular component morphogenesis GO:0032989 336 0.063
appendage morphogenesis GO:0035107 56 0.062
insulin like growth factor receptor signaling pathway GO:0048009 4 0.061
generation of neurons GO:0048699 385 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.060
regulation of protein localization to nucleus GO:1900180 2 0.058
heart morphogenesis GO:0003007 156 0.056
negative regulation of cytoplasmic transport GO:1903650 2 0.056
positive regulation of cell adhesion GO:0045785 1 0.055
ubiquitin dependent protein catabolic process GO:0006511 3 0.055
hemostasis GO:0007599 13 0.054
taxis GO:0042330 109 0.054
cell adhesion GO:0007155 40 0.053
response to external stimulus GO:0009605 264 0.053
regulation of intracellular protein transport GO:0033157 3 0.052
biosynthetic process GO:0009058 294 0.052
single organism cell adhesion GO:0098602 29 0.052
regulation of protein import into nucleus GO:0042306 2 0.052
positive regulation of biological process GO:0048518 253 0.052
Worm
regulation of nucleocytoplasmic transport GO:0046822 2 0.051
skeletal system development GO:0001501 181 0.051
locomotor rhythm GO:0045475 3 0.051
determination of dorsal ventral asymmetry GO:0048262 34 0.050
convergent extension GO:0060026 118 0.050
organelle organization GO:0006996 227 0.050
muscle cell differentiation GO:0042692 139 0.049
dorsal ventral pattern formation GO:0009953 125 0.048
rna biosynthetic process GO:0032774 181 0.048
cellular macromolecule metabolic process GO:0044260 391 0.047
cellular component assembly GO:0022607 170 0.047
modification dependent protein catabolic process GO:0019941 3 0.047
single organism nuclear import GO:1902593 3 0.047
cell morphogenesis GO:0000902 289 0.047
embryonic appendage morphogenesis GO:0035113 30 0.046
Zebrafish
regulation of protein binding GO:0043393 3 0.046
digestive tract development GO:0048565 265 0.045
organic cyclic compound metabolic process GO:1901360 301 0.045
cellular component movement GO:0006928 335 0.045
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.044
regulation of molecular function GO:0065009 70 0.044
regulation of protein targeting GO:1903533 2 0.044
embryonic viscerocranium morphogenesis GO:0048703 52 0.044
cell migration GO:0016477 237 0.044
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
cell projection organization GO:0030030 284 0.043
gastrulation GO:0007369 208 0.042
negative regulation of intracellular transport GO:0032387 3 0.042
regulation of biological quality GO:0065008 263 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.042
central nervous system development GO:0007417 387 0.042
pectoral fin development GO:0033339 50 0.041
protein import GO:0017038 3 0.041
protein import into nucleus GO:0006606 3 0.040
neuron projection development GO:0031175 180 0.040
regulation of primary metabolic process GO:0080090 311 0.039
skeletal muscle organ development GO:0060538 78 0.039
regulation of cellular protein catabolic process GO:1903362 1 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
determination of bilateral symmetry GO:0009855 204 0.038
striated muscle tissue development GO:0014706 110 0.038
protein catabolic process GO:0030163 7 0.037
rhythmic process GO:0048511 21 0.037
negative regulation of cellular catabolic process GO:0031330 3 0.037
cell morphogenesis involved in differentiation GO:0000904 195 0.037
cellular component disassembly GO:0022411 1 0.036
neuron differentiation GO:0030182 353 0.036
regulation of protein localization to plasma membrane GO:1903076 1 0.036
cellular response to organic cyclic compound GO:0071407 38 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
heterocycle biosynthetic process GO:0018130 215 0.034
response to chemical GO:0042221 320 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
transport GO:0006810 220 0.034
negative regulation of catabolic process GO:0009895 3 0.034
regulation of rho protein signal transduction GO:0035023 2 0.034
protein targeting to nucleus GO:0044744 3 0.033
sensory perception GO:0007600 39 0.033
negative regulation of signaling GO:0023057 96 0.033
protein localization to nucleus GO:0034504 3 0.033
cellular biosynthetic process GO:0044249 286 0.033
regulation of cell substrate adhesion GO:0010810 1 0.032
neuron projection morphogenesis GO:0048812 161 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
behavior GO:0007610 74 0.032
morphogenesis of an epithelium GO:0002009 333 0.032
nuclear import GO:0051170 3 0.032
regulation of canonical wnt signaling pathway GO:0060828 34 0.031
reproduction GO:0000003 40 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
regulation of biosynthetic process GO:0009889 250 0.030
axis specification GO:0009798 43 0.030
protein localization to plasma membrane GO:0072659 1 0.030
cytoskeleton organization GO:0007010 96 0.030
negative regulation of macromolecule metabolic process GO:0010605 76 0.030
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.029
cellular component biogenesis GO:0044085 178 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
localization of cell GO:0051674 244 0.029
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.029
single organism metabolic process GO:0044710 217 0.029
single organismal cell cell adhesion GO:0016337 29 0.029
cell proliferation GO:0008283 80 0.029
regulation of cellular component movement GO:0051270 55 0.029
ras protein signal transduction GO:0007265 7 0.029
myofibril assembly GO:0030239 48 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
nephron tubule morphogenesis GO:0072078 1 0.028
protein metabolic process GO:0019538 183 0.028
single organism reproductive process GO:0044702 40 0.028
lens fiber cell morphogenesis GO:0070309 3 0.028
regulation of cell communication GO:0010646 232 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.027
actin cytoskeleton organization GO:0030036 63 0.027
regulation of body fluid levels GO:0050878 16 0.027
germ line stem cell division GO:0042078 1 0.027
regulation of developmental process GO:0050793 247 0.027
lipid storage GO:0019915 1 0.027
regulation of metabolic process GO:0019222 359 0.026
striated muscle cell differentiation GO:0051146 129 0.026
response to amino acid GO:0043200 2 0.026
regulation of wnt signaling pathway GO:0030111 53 0.026
oxoacid metabolic process GO:0043436 31 0.026
negative regulation of protein import into nucleus GO:0042308 2 0.026
gamete generation GO:0007276 33 0.026
regulation of bmp signaling pathway GO:0030510 39 0.026
notochord morphogenesis GO:0048570 17 0.026
cell adhesion mediated by integrin GO:0033627 1 0.026
regulation of ion transmembrane transport GO:0034765 18 0.025
regulation of cell differentiation GO:0045595 142 0.025
small molecule metabolic process GO:0044281 77 0.025
extracellular matrix organization GO:0030198 27 0.025
organic substance transport GO:0071702 58 0.025
cell part morphogenesis GO:0032990 246 0.025
formation of primary germ layer GO:0001704 62 0.024
embryonic caudal fin morphogenesis GO:0035124 3 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
axon development GO:0061564 166 0.024
muscle cell development GO:0055001 115 0.024
embryonic skeletal system development GO:0048706 97 0.024
cell migration involved in gastrulation GO:0042074 79 0.023
protein complex biogenesis GO:0070271 30 0.023
ovulation cycle GO:0042698 2 0.023
regeneration GO:0031099 91 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
sensory organ development GO:0007423 393 0.023
primary neural tube formation GO:0014020 1 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.023
organic substance biosynthetic process GO:1901576 289 0.022
regulation of protein complex assembly GO:0043254 3 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.022
detection of abiotic stimulus GO:0009582 24 0.022
negative regulation of rho protein signal transduction GO:0035024 1 0.022
cellular component maintenance GO:0043954 3 0.022
cell substrate junction assembly GO:0007044 2 0.022
golgi vesicle transport GO:0048193 3 0.022
protein polymerization GO:0051258 4 0.021
neuroblast proliferation GO:0007405 2 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
multi organism process GO:0051704 134 0.021
response to endogenous stimulus GO:0009719 83 0.021
internal protein amino acid acetylation GO:0006475 2 0.020
establishment of protein localization to plasma membrane GO:0090002 1 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
protein complex subunit organization GO:0071822 46 0.020
single organism cellular localization GO:1902580 46 0.020
small gtpase mediated signal transduction GO:0007264 8 0.020
muscle organ development GO:0007517 101 0.020
wnt signaling pathway GO:0016055 80 0.020
collagen biosynthetic process GO:0032964 2 0.020
stem cell division GO:0017145 1 0.020
extracellular matrix assembly GO:0085029 1 0.020
muscle tissue development GO:0060537 110 0.020
superoxide metabolic process GO:0006801 2 0.020
negative regulation of metabolic process GO:0009892 86 0.020
actomyosin structure organization GO:0031032 53 0.020
heart process GO:0003015 71 0.019
regulation of protein transport GO:0051223 3 0.019
angiogenesis GO:0001525 158 0.019
cellular localization GO:0051641 97 0.019
chemotaxis GO:0006935 104 0.019
cellular response to growth factor stimulus GO:0071363 39 0.019
regulation of dna replication GO:0006275 3 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
striated muscle myosin thick filament assembly GO:0071688 6 0.019
notochord development GO:0030903 54 0.019
circadian behavior GO:0048512 5 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.019
tissue regeneration GO:0042246 74 0.019
cellular response to endogenous stimulus GO:0071495 68 0.018
cation transmembrane transport GO:0098655 65 0.018
homeostasis of number of cells within a tissue GO:0048873 4 0.018
ion transmembrane transport GO:0034220 91 0.018
rhythmic behavior GO:0007622 5 0.018
striated muscle cell development GO:0055002 108 0.018
ion transport GO:0006811 114 0.017
establishment of localization in cell GO:0051649 77 0.017
catabolic process GO:0009056 32 0.017
regulation of cytokine production GO:0001817 3 0.017
muscle cell migration GO:0014812 4 0.017
actin filament polymerization GO:0030041 2 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
lens fiber cell development GO:0070307 3 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
negative regulation of cell migration GO:0030336 17 0.016
positive regulation of synapse assembly GO:0051965 1 0.016
skeletal system morphogenesis GO:0048705 102 0.016
response to light stimulus GO:0009416 46 0.016
locomotory behavior GO:0007626 34 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
single organism biosynthetic process GO:0044711 71 0.016
meiotic cell cycle process GO:1903046 3 0.016
intracellular transport GO:0046907 32 0.016
blood circulation GO:0008015 87 0.016
response to vitamin GO:0033273 3 0.016
rho protein signal transduction GO:0007266 5 0.016
vasculature development GO:0001944 278 0.016
negative regulation of gene expression GO:0010629 65 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
muscle contraction GO:0006936 18 0.015
regulation of endopeptidase activity GO:0052548 23 0.015
lipid homeostasis GO:0055088 3 0.015
regulation of rna metabolic process GO:0051252 224 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
protein complex disassembly GO:0043241 1 0.015
outflow tract morphogenesis GO:0003151 1 0.015
actin filament based process GO:0030029 64 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of localization GO:0032879 104 0.015
positive regulation of cell substrate adhesion GO:0010811 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
phosphorus metabolic process GO:0006793 109 0.015
digestive tract morphogenesis GO:0048546 231 0.015
cellular macromolecule localization GO:0070727 21 0.015
cell projection morphogenesis GO:0048858 244 0.015
organic acid metabolic process GO:0006082 31 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
cellular protein modification process GO:0006464 100 0.014
protein heterooligomerization GO:0051291 1 0.014
response to wounding GO:0009611 116 0.014
macromolecule catabolic process GO:0009057 15 0.014
regulation of system process GO:0044057 40 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
microtubule organizing center organization GO:0031023 1 0.014
detection of stimulus GO:0051606 29 0.014
actin filament organization GO:0007015 15 0.014
eye development GO:0001654 277 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
positive regulation of transport GO:0051050 2 0.014
positive regulation of developmental process GO:0051094 50 0.014
multi organism cellular process GO:0044764 2 0.014
negative regulation of molecular function GO:0044092 23 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
embryonic heart tube development GO:0035050 133 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
gene expression GO:0010467 252 0.013
single organism organelle organization GO:1902589 199 0.013
positive regulation of cell cycle GO:0045787 3 0.013
pectoral fin morphogenesis GO:0035138 29 0.013
epithelial cell development GO:0002064 42 0.013
organic substance catabolic process GO:1901575 28 0.013
negative regulation of bmp signaling pathway GO:0030514 13 0.012
regulation of filopodium assembly GO:0051489 2 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
negative regulation of defense response GO:0031348 2 0.012
intracellular signal transduction GO:0035556 85 0.012
negative regulation of immune response GO:0050777 2 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
cellular ketone metabolic process GO:0042180 11 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
axon guidance GO:0007411 86 0.012
regulation of reproductive process GO:2000241 4 0.012
response to growth factor GO:0070848 39 0.012
negative regulation of intracellular signal transduction GO:1902532 22 0.012
negative regulation of translation GO:0017148 1 0.012
bmp signaling pathway GO:0030509 52 0.012
detection of light stimulus GO:0009583 12 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
regulation of cell motility GO:2000145 46 0.012
endosomal transport GO:0016197 2 0.012
somite development GO:0061053 96 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
centrosome organization GO:0051297 1 0.012
macromolecule localization GO:0033036 54 0.012
negative regulation of catalytic activity GO:0043086 21 0.011
protein complex assembly GO:0006461 30 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
phagocytosis GO:0006909 3 0.011
negative regulation of developmental process GO:0051093 65 0.011
phagocytosis engulfment GO:0006911 1 0.011
macromolecular complex assembly GO:0065003 35 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of vitamin metabolic process GO:0030656 6 0.011
regulation of cellular component organization GO:0051128 86 0.011
embryonic pectoral fin morphogenesis GO:0035118 24 0.011
regulation of smoothened signaling pathway GO:0008589 18 0.011
defense response to fungus GO:0050832 2 0.011
regulation of transporter activity GO:0032409 2 0.011
kupffer s vesicle development GO:0070121 50 0.011
organism emergence from protective structure GO:0071684 4 0.011
regulation of cell projection assembly GO:0060491 4 0.011
cellular response to nutrient levels GO:0031669 2 0.011
blood vessel development GO:0001568 246 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
camera type eye development GO:0043010 222 0.011
negative regulation of innate immune response GO:0045824 2 0.010
mesoderm formation GO:0001707 43 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
monovalent inorganic cation transport GO:0015672 42 0.010
inorganic ion transmembrane transport GO:0098660 57 0.010
protein modification process GO:0036211 100 0.010
positive regulation of gliogenesis GO:0014015 2 0.010
tube closure GO:0060606 1 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
stem cell maintenance GO:0019827 4 0.010
lipid metabolic process GO:0006629 52 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
regulation of nervous system development GO:0051960 90 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010

hmcn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.065
Human
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.032
bone development disease DOID:0080006 0 0.023
bone disease DOID:0080001 0 0.023
nervous system disease DOID:863 0 0.016
Human
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.010
dysostosis DOID:1934 0 0.010
synostosis DOID:11971 0 0.010