Danio rerio

38 known processes

hmcn2

hemicentin 2

(Aliases: cb30,sb:cb30,si:ch211-204c5.1)

hmcn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis GO:0000902 289 0.271
neuron development GO:0048666 262 0.216
cell morphogenesis involved in differentiation GO:0000904 195 0.199
blood vessel development GO:0001568 246 0.134
regulation of synapse assembly GO:0051963 3 0.128
regulation of filopodium assembly GO:0051489 2 0.127
muscle structure development GO:0061061 196 0.125
response to stress GO:0006950 263 0.116
cell projection organization GO:0030030 284 0.111
regulation of cell projection organization GO:0031344 44 0.110
locomotion GO:0040011 313 0.110
regulation of biological quality GO:0065008 263 0.095
regulation of developmental process GO:0050793 247 0.094
regulation of synapse organization GO:0050807 3 0.091
synaptic growth at neuromuscular junction GO:0051124 2 0.087
positive regulation of biological process GO:0048518 253 0.085
response to chemical GO:0042221 320 0.079
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.078
extracellular matrix organization GO:0030198 27 0.078
skeletal system development GO:0001501 181 0.075
regulation of neurogenesis GO:0050767 87 0.074
organelle organization GO:0006996 227 0.074
cell projection morphogenesis GO:0048858 244 0.071
regulation of multicellular organismal development GO:2000026 223 0.069
regulation of cell morphogenesis GO:0022604 42 0.068
regulation of transcription dna templated GO:0006355 213 0.067
response to external stimulus GO:0009605 264 0.065
skeletal muscle organ development GO:0060538 78 0.063
regulation of protein catabolic process GO:0042176 1 0.060
larval development GO:0002164 2 0.059
muscle attachment GO:0016203 9 0.059
single organism cell adhesion GO:0098602 29 0.058
organic substance biosynthetic process GO:1901576 289 0.057
positive regulation of cell adhesion GO:0045785 1 0.055
cellular component movement GO:0006928 335 0.055
regulation of anatomical structure morphogenesis GO:0022603 130 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
cellular nitrogen compound metabolic process GO:0034641 290 0.050
generation of neurons GO:0048699 385 0.048
neuron projection development GO:0031175 180 0.048
regulation of cell development GO:0060284 100 0.047
extracellular structure organization GO:0043062 27 0.047
cell motility GO:0048870 244 0.046
regulation of cellular component organization GO:0051128 86 0.045
regulation of multicellular organismal process GO:0051239 277 0.040
neuron projection guidance GO:0097485 86 0.040
signal transduction GO:0007165 455 0.040
positive regulation of cellular process GO:0048522 201 0.040
regulation of synapse structure and activity GO:0050803 5 0.040
nuclear transport GO:0051169 4 0.039
negative regulation of chemotaxis GO:0050922 4 0.038
regulation of signaling GO:0023051 235 0.038
neuron differentiation GO:0030182 353 0.037
cell part morphogenesis GO:0032990 246 0.037
positive regulation of developmental process GO:0051094 50 0.037
ameboidal type cell migration GO:0001667 143 0.037
bmp signaling pathway GO:0030509 52 0.037
vasculature development GO:0001944 278 0.036
gene expression GO:0010467 252 0.036
developmental growth GO:0048589 166 0.036
regulation of cell communication GO:0010646 232 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
negative regulation of synapse assembly GO:0051964 2 0.034
negative regulation of ras protein signal transduction GO:0046580 1 0.034
nuclear import GO:0051170 3 0.033
axon guidance GO:0007411 86 0.033
positive regulation of protein kinase b signaling GO:0051897 1 0.033
cell growth GO:0016049 57 0.033
regulation of signal transduction GO:0009966 225 0.032
cognition GO:0050890 1 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
regulation of response to stimulus GO:0048583 269 0.031
localization of cell GO:0051674 244 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
regulation of primary metabolic process GO:0080090 311 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
regulation of dna replication GO:0006275 3 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
cell migration GO:0016477 237 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
gtp metabolic process GO:0046039 4 0.028
peptidyl threonine modification GO:0018210 1 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
basement membrane organization GO:0071711 5 0.028
regulation of nervous system development GO:0051960 90 0.028
behavior GO:0007610 74 0.028
appendage morphogenesis GO:0035107 56 0.028
negative regulation of cellular process GO:0048523 283 0.028
protein import GO:0017038 3 0.027
lipid metabolic process GO:0006629 52 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of cell differentiation GO:0045595 142 0.027
cell matrix adhesion GO:0007160 4 0.026
striated muscle cell differentiation GO:0051146 129 0.026
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.025
interspecies interaction between organisms GO:0044419 4 0.025
protein localization to nucleus GO:0034504 3 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
lens fiber cell development GO:0070307 3 0.024
aging GO:0007568 2 0.024
regulation of neuron projection development GO:0010975 40 0.024
rho protein signal transduction GO:0007266 5 0.023
axonogenesis GO:0007409 152 0.023
bleb assembly GO:0032060 1 0.023
gastrulation GO:0007369 208 0.023
reproduction GO:0000003 40 0.023
positive regulation of locomotion GO:0040017 14 0.022
response to glucocorticoid GO:0051384 1 0.022
cellular protein metabolic process GO:0044267 129 0.022
muscle cell migration GO:0014812 4 0.022
fin development GO:0033333 77 0.022
regulation of rho protein signal transduction GO:0035023 2 0.021
regulation of cell shape GO:0008360 1 0.021
interaction with host GO:0051701 4 0.021
enzyme linked receptor protein signaling pathway GO:0007167 106 0.021
regulation of locomotion GO:0040012 55 0.021
lens fiber cell morphogenesis GO:0070309 3 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
protein import into nucleus GO:0006606 3 0.021
embryonic organ morphogenesis GO:0048562 274 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
embryonic skeletal system development GO:0048706 97 0.020
blood vessel morphogenesis GO:0048514 216 0.020
angiogenesis GO:0001525 158 0.020
growth GO:0040007 174 0.020
establishment of localization in cell GO:0051649 77 0.020
taxis GO:0042330 109 0.020
cellular response to stress GO:0033554 62 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.020
gastrulation with mouth forming second GO:0001702 44 0.019
multicellular organism growth GO:0035264 4 0.019
medial fin development GO:0033338 16 0.019
lens development in camera type eye GO:0002088 22 0.019
phagocytosis GO:0006909 3 0.019
cellular component morphogenesis GO:0032989 336 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
protein metabolic process GO:0019538 183 0.019
protein targeting to nucleus GO:0044744 3 0.018
regulation of reproductive process GO:2000241 4 0.018
single organismal cell cell adhesion GO:0016337 29 0.018
multicellular organismal metabolic process GO:0044236 2 0.018
system process GO:0003008 185 0.018
cytoskeleton organization GO:0007010 96 0.018
single organism transport GO:0044765 206 0.018
positive regulation of transport GO:0051050 2 0.018
negative regulation of dna replication GO:0008156 2 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.017
axon development GO:0061564 166 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.017
cellular response to organic substance GO:0071310 105 0.017
homeostatic process GO:0042592 142 0.017
regionalization GO:0003002 274 0.017
extracellular matrix assembly GO:0085029 1 0.016
viral process GO:0016032 1 0.016
biosynthetic process GO:0009058 294 0.016
cell substrate adhesion GO:0031589 4 0.016
tube morphogenesis GO:0035239 349 0.016
positive regulation of catabolic process GO:0009896 4 0.016
transport GO:0006810 220 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
microtubule organizing center organization GO:0031023 1 0.015
intracellular signal transduction GO:0035556 85 0.015
protein acylation GO:0043543 3 0.015
negative regulation of developmental process GO:0051093 65 0.015
endosomal transport GO:0016197 2 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
centrosome cycle GO:0007098 1 0.015
single organism organelle organization GO:1902589 199 0.015
multi organism cellular process GO:0044764 2 0.015
axonal defasciculation GO:0007414 2 0.014
skin morphogenesis GO:0043589 7 0.014
muscle organ development GO:0007517 101 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
single fertilization GO:0007338 3 0.014
embryonic medial fin morphogenesis GO:0035122 6 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
centrosome organization GO:0051297 1 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
response to corticosteroid GO:0031960 1 0.013
cell proliferation GO:0008283 80 0.013
sensory perception of smell GO:0007608 2 0.013
ras protein signal transduction GO:0007265 7 0.012
neuron projection morphogenesis GO:0048812 161 0.012
establishment of localization GO:0051234 244 0.012
heterocycle metabolic process GO:0046483 290 0.012
positive regulation of cytokine production GO:0001819 2 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
maintenance of location GO:0051235 4 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
convergent extension GO:0060026 118 0.012
amine metabolic process GO:0009308 2 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
rna biosynthetic process GO:0032774 181 0.012
single organism metabolic process GO:0044710 217 0.012
single organism localization GO:1902578 225 0.012
skeletal muscle tissue development GO:0007519 67 0.012
multi organism process GO:0051704 134 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
morphogenesis of an epithelium GO:0002009 333 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
trabecula formation GO:0060343 2 0.011
embryonic organ development GO:0048568 381 0.011
striated muscle tissue development GO:0014706 110 0.011
cell migration involved in heart development GO:0060973 22 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
autophagy GO:0006914 4 0.011
chordate embryonic development GO:0043009 271 0.011
macromolecule localization GO:0033036 54 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
response to oxygen levels GO:0070482 25 0.011
protein acetylation GO:0006473 2 0.011
cellular protein catabolic process GO:0044257 4 0.011
cell migration involved in sprouting angiogenesis GO:0002042 8 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of developmental growth GO:0048638 38 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.010
cell adhesion mediated by integrin GO:0033627 1 0.010
cellular lipid metabolic process GO:0044255 36 0.010
sprouting angiogenesis GO:0002040 53 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
transcription dna templated GO:0006351 181 0.010
synapse assembly GO:0007416 9 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
ribonucleoside biosynthetic process GO:0042455 2 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of protein targeting GO:1903533 2 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
negative regulation of behavior GO:0048521 6 0.010

hmcn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.045
muscular disease DOID:0080000 0 0.030
muscle tissue disease DOID:66 0 0.030
myopathy DOID:423 0 0.030
disease of metabolism DOID:0014667 0 0.024
nervous system disease DOID:863 0 0.021
inherited metabolic disorder DOID:655 0 0.015
eye and adnexa disease DOID:1492 0 0.011
sensory system disease DOID:0050155 0 0.011