Danio rerio

0 known processes

hmgb3b

high-mobility group box 3b

(Aliases: zgc:112073,wu:fa19b06,fa19b06,wu:fj43d02,hmgb3,fj43d02)

hmgb3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular biosynthetic process GO:0044249 286 0.254
response to organic substance GO:0010033 153 0.168
signal transduction GO:0007165 455 0.155
biosynthetic process GO:0009058 294 0.139
regulation of epithelial cell proliferation GO:0050678 3 0.130
rna biosynthetic process GO:0032774 181 0.114
nucleobase containing compound biosynthetic process GO:0034654 205 0.102
regulation of metabolic process GO:0019222 359 0.093
transport GO:0006810 220 0.079
aging GO:0007568 2 0.078
cellular macromolecule biosynthetic process GO:0034645 224 0.073
single organism metabolic process GO:0044710 217 0.071
organic substance biosynthetic process GO:1901576 289 0.070
mitochondrion organization GO:0007005 4 0.067
response to external stimulus GO:0009605 264 0.063
cellular nitrogen compound biosynthetic process GO:0044271 218 0.063
response to chemical GO:0042221 320 0.062
cellular macromolecule metabolic process GO:0044260 391 0.061
regulation of biosynthetic process GO:0009889 250 0.060
regulation of signaling GO:0023051 235 0.059
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.058
positive regulation of epithelial cell proliferation GO:0050679 1 0.056
single organism organelle organization GO:1902589 199 0.054
regulation of gene expression GO:0010468 265 0.053
positive regulation of cell cycle GO:0045787 3 0.052
apoptotic process GO:0006915 116 0.051
regulation of cellular biosynthetic process GO:0031326 245 0.050
regulation of cellular metabolic process GO:0031323 320 0.050
larval development GO:0002164 2 0.049
heterocycle biosynthetic process GO:0018130 215 0.048
purine nucleoside monophosphate catabolic process GO:0009128 4 0.048
neuron development GO:0048666 262 0.047
organic cyclic compound biosynthetic process GO:1901362 223 0.047
cell projection morphogenesis GO:0048858 244 0.046
mesenchymal cell differentiation GO:0048762 87 0.046
cellular component movement GO:0006928 335 0.045
nucleic acid templated transcription GO:0097659 181 0.044
cellular response to nutrient levels GO:0031669 2 0.043
mesenchyme development GO:0060485 127 0.042
cellular response to starvation GO:0009267 1 0.041
regulation of cell death GO:0010941 103 0.041
death GO:0016265 121 0.041
regulation of signal transduction GO:0009966 225 0.040
embryonic organ morphogenesis GO:0048562 274 0.040
gene expression GO:0010467 252 0.040
oxoacid metabolic process GO:0043436 31 0.039
transcription dna templated GO:0006351 181 0.039
regulation of nucleic acid templated transcription GO:1903506 213 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
lipid storage GO:0019915 1 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.034
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.034
neuron differentiation GO:0030182 353 0.034
stem cell development GO:0048864 82 0.034
response to stress GO:0006950 263 0.033
chordate embryonic development GO:0043009 271 0.033
positive regulation of myeloid cell differentiation GO:0045639 2 0.033
cellular response to external stimulus GO:0071496 2 0.032
cell death GO:0008219 121 0.032
cellular protein catabolic process GO:0044257 4 0.032
cellular response to chemical stimulus GO:0070887 157 0.031
maintenance of location GO:0051235 4 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
organic acid metabolic process GO:0006082 31 0.031
vasculature development GO:0001944 278 0.031
blood vessel morphogenesis GO:0048514 216 0.031
nucleoside monophosphate catabolic process GO:0009125 4 0.031
immune system process GO:0002376 241 0.030
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.030
protein metabolic process GO:0019538 183 0.030
regulation of synaptic plasticity GO:0048167 1 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
ribonucleoside monophosphate catabolic process GO:0009158 4 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
programmed cell death GO:0012501 119 0.028
specification of symmetry GO:0009799 204 0.028
somitogenesis GO:0001756 87 0.028
single organism biosynthetic process GO:0044711 71 0.028
neuron projection development GO:0031175 180 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
response to endogenous stimulus GO:0009719 83 0.027
negative regulation of cellular process GO:0048523 283 0.027
Mouse
regulation of multicellular organism growth GO:0040014 4 0.026
blood vessel development GO:0001568 246 0.026
autophagy GO:0006914 4 0.026
regulation of endothelial cell proliferation GO:0001936 1 0.026
cell migration GO:0016477 237 0.025
regulation of cell communication GO:0010646 232 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
anterior posterior pattern specification GO:0009952 152 0.024
muscle structure development GO:0061061 196 0.024
regulation of primary metabolic process GO:0080090 311 0.024
hormone biosynthetic process GO:0042446 3 0.024
cellular component morphogenesis GO:0032989 336 0.024
mesenchymal cell development GO:0014031 78 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
mitochondrial transport GO:0006839 2 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
response to oxygen containing compound GO:1901700 55 0.023
establishment of localization GO:0051234 244 0.023
response to other organism GO:0051707 97 0.023
positive regulation of transport GO:0051050 2 0.022
growth GO:0040007 174 0.022
locomotion GO:0040011 313 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.022
regulation of biological quality GO:0065008 263 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.022
positive regulation of cellular process GO:0048522 201 0.022
fatty acid biosynthetic process GO:0006633 4 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
amine metabolic process GO:0009308 2 0.021
ameboidal type cell migration GO:0001667 143 0.021
regulation of response to stimulus GO:0048583 269 0.021
cell motility GO:0048870 244 0.021
cellular response to organic substance GO:0071310 105 0.021
gtp catabolic process GO:0006184 2 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
regulation of programmed cell death GO:0043067 101 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
positive regulation of biological process GO:0048518 253 0.020
nuclear transport GO:0051169 4 0.020
positive regulation of catabolic process GO:0009896 4 0.020
system process GO:0003008 185 0.020
membrane fusion GO:0061025 2 0.020
pigment cell differentiation GO:0050931 38 0.020
organelle fusion GO:0048284 3 0.020
negative regulation of signaling GO:0023057 96 0.020
spindle assembly GO:0051225 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
regulation of rna biosynthetic process GO:2001141 213 0.019
regulation of autophagy GO:0010506 3 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
determination of left right symmetry GO:0007368 179 0.019
neural crest cell differentiation GO:0014033 72 0.019
response to nutrient GO:0007584 3 0.019
cellular response to endogenous stimulus GO:0071495 68 0.019
organelle organization GO:0006996 227 0.019
positive regulation of muscle organ development GO:0048636 1 0.019
determination of bilateral symmetry GO:0009855 204 0.019
cellular component biogenesis GO:0044085 178 0.019
regionalization GO:0003002 274 0.019
regulation of apoptotic process GO:0042981 98 0.019
regulation of transcription dna templated GO:0006355 213 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
single organism transport GO:0044765 206 0.019
nucleic acid metabolic process GO:0090304 244 0.018
carboxylic acid biosynthetic process GO:0046394 12 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
positive regulation of muscle tissue development GO:1901863 1 0.018
microtubule organizing center organization GO:0031023 1 0.018
response to biotic stimulus GO:0009607 97 0.018
angiogenesis GO:0001525 158 0.018
response to corticosteroid GO:0031960 1 0.018
regulation of rna metabolic process GO:0051252 224 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
localization of cell GO:0051674 244 0.017
neurotransmitter transport GO:0006836 2 0.017
embryonic organ development GO:0048568 381 0.017
atp catabolic process GO:0006200 4 0.017
regulation of oocyte development GO:0060281 3 0.017
response to hormone GO:0009725 48 0.017
tube morphogenesis GO:0035239 349 0.017
cell cycle GO:0007049 93 0.017
heart development GO:0007507 313 0.017
macroautophagy GO:0016236 1 0.017
establishment of protein localization to organelle GO:0072594 4 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
phagocytosis GO:0006909 3 0.016
protein targeting to nucleus GO:0044744 3 0.016
multicellular organism growth GO:0035264 4 0.016
centrosome cycle GO:0007098 1 0.016
cell projection organization GO:0030030 284 0.016
macromolecule localization GO:0033036 54 0.015
regulation of localization GO:0032879 104 0.015
multicellular organismal response to stress GO:0033555 2 0.015
spermatid differentiation GO:0048515 2 0.015
centrosome organization GO:0051297 1 0.015
small molecule metabolic process GO:0044281 77 0.015
rna metabolic process GO:0016070 219 0.015
gtp metabolic process GO:0046039 4 0.015
meiotic cell cycle process GO:1903046 3 0.015
protein import GO:0017038 3 0.015
homeostatic process GO:0042592 142 0.015
neural crest cell development GO:0014032 62 0.015
single organism membrane fusion GO:0044801 2 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.015
membrane lipid biosynthetic process GO:0046467 2 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of binding GO:0051098 3 0.015
estrogen metabolic process GO:0008210 2 0.015
segmentation GO:0035282 97 0.014
cell morphogenesis GO:0000902 289 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
rna localization GO:0006403 4 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.014
stem cell maintenance GO:0019827 4 0.014
gastrulation GO:0007369 208 0.014
regulation of cysteine type endopeptidase activity GO:2000116 21 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
oxidation reduction process GO:0055114 41 0.014
cell part morphogenesis GO:0032990 246 0.014
somite development GO:0061053 96 0.014
translational initiation GO:0006413 3 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
cellular protein metabolic process GO:0044267 129 0.014
single organism localization GO:1902578 225 0.014
regulation of protein transport GO:0051223 3 0.013
positive regulation of peptidase activity GO:0010952 10 0.013
adult behavior GO:0030534 2 0.013
response to monosaccharide GO:0034284 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
developmental growth GO:0048589 166 0.013
protein homooligomerization GO:0051260 3 0.013
negative regulation of biological process GO:0048519 304 0.013
Mouse
single organism membrane organization GO:0044802 20 0.013
negative regulation of secretion GO:0051048 2 0.013
response to glucocorticoid GO:0051384 1 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
neurotransmitter secretion GO:0007269 2 0.013
brain development GO:0007420 293 0.013
taxis GO:0042330 109 0.013
central nervous system development GO:0007417 387 0.012
cellular response to stress GO:0033554 62 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
cellular hormone metabolic process GO:0034754 19 0.012
response to external biotic stimulus GO:0043207 97 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
ion homeostasis GO:0050801 41 0.012
spermatid development GO:0007286 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
cognition GO:0050890 1 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
catecholamine metabolic process GO:0006584 2 0.012
transmembrane transport GO:0055085 120 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
fatty acid elongation GO:0030497 1 0.012
energy reserve metabolic process GO:0006112 2 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
cellular ketone metabolic process GO:0042180 11 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of cell activation GO:0050865 1 0.011
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
response to drug GO:0042493 3 0.011
response to steroid hormone GO:0048545 35 0.011
neuroblast proliferation GO:0007405 2 0.011
dna biosynthetic process GO:0071897 3 0.011
regulation of locomotion GO:0040012 55 0.011
axonogenesis GO:0007409 152 0.011
intracellular signal transduction GO:0035556 85 0.011
response to carbohydrate GO:0009743 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
cytoskeleton organization GO:0007010 96 0.011
zymogen activation GO:0031638 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of hydrolase activity GO:0051345 13 0.011
regulation of nuclease activity GO:0032069 1 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
response to glucose GO:0009749 3 0.011
b cell differentiation GO:0030183 1 0.010
Mouse
monocarboxylic acid biosynthetic process GO:0072330 12 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
regulation of organ growth GO:0046620 3 0.010
protein localization to nucleus GO:0034504 3 0.010
response to cold GO:0009409 4 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
sensory organ development GO:0007423 393 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
cellular response to oxygen levels GO:0071453 1 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
Mouse
negative regulation of protein transport GO:0051224 3 0.010
exocytosis GO:0006887 1 0.010

hmgb3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
inherited metabolic disorder DOID:655 0 0.041
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.028
motor neuron disease DOID:231 0 0.026
central nervous system disease DOID:331 0 0.026
amyotrophic lateral sclerosis DOID:332 0 0.026
neurodegenerative disease DOID:1289 0 0.026
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010