Danio rerio

0 known processes

hoxb2a

homeo box B2a

(Aliases: hoxb2,hm:zehn0229,Z-151)

hoxb2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell migration in hindbrain GO:0021535 7 0.981
Zebrafish
neural keel formation GO:0014025 1 0.971
Zebrafish
regionalization GO:0003002 274 0.962
Mouse Fly
preganglionic parasympathetic nervous system development GO:0021783 6 0.957
Zebrafish Mouse
facial nerve development GO:0021561 3 0.939
Zebrafish Mouse
rhombomere formation GO:0021594 12 0.933
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.928
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.924
Zebrafish Mouse
rhombomere development GO:0021546 19 0.922
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.922
Mouse
rhombomere morphogenesis GO:0021593 17 0.895
Zebrafish
rhombomere 4 development GO:0021570 5 0.866
Zebrafish Mouse
locomotion GO:0040011 313 0.859
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.832
Zebrafish
rhombomere 4 morphogenesis GO:0021661 5 0.826
Zebrafish
immune system process GO:0002376 241 0.825
blood vessel morphogenesis GO:0048514 216 0.818
regulation of cell communication GO:0010646 232 0.812
neuron projection guidance GO:0097485 86 0.805
embryonic viscerocranium morphogenesis GO:0048703 52 0.803
cell fate specification GO:0001708 68 0.783
tube morphogenesis GO:0035239 349 0.776
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.774
cell motility GO:0048870 244 0.760
Zebrafish
digestive system development GO:0055123 289 0.747
cell migration GO:0016477 237 0.740
Zebrafish
glossopharyngeal nerve development GO:0021563 1 0.714
skeletal system development GO:0001501 181 0.713
Mouse
chordate embryonic development GO:0043009 271 0.705
Zebrafish Mouse
signal transduction GO:0007165 455 0.690
embryonic skeletal system development GO:0048706 97 0.689
Mouse
generation of neurons GO:0048699 385 0.686
anterior posterior pattern specification GO:0009952 152 0.620
Mouse
cell fate commitment GO:0045165 99 0.617
regulation of developmental process GO:0050793 247 0.615
regulation of response to stimulus GO:0048583 269 0.598
regulation of multicellular organismal development GO:2000026 223 0.579
renal system development GO:0072001 94 0.577
appendage morphogenesis GO:0035107 56 0.574
central nervous system development GO:0007417 387 0.559
Zebrafish Mouse
dorsal ventral pattern formation GO:0009953 125 0.553
Mouse
fin morphogenesis GO:0033334 53 0.547
regulation of cellular metabolic process GO:0031323 320 0.546
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.542
Zebrafish
embryonic organ development GO:0048568 381 0.535
Mouse
regulation of cell differentiation GO:0045595 142 0.511
collateral sprouting of intact axon in response to injury GO:0048673 2 0.506
cellular component movement GO:0006928 335 0.506
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.506
motor neuron axon guidance GO:0008045 23 0.500
positive regulation of cellular process GO:0048522 201 0.498
Zebrafish
epidermal cell fate specification GO:0009957 4 0.496
regulation of cell fate specification GO:0042659 20 0.491
regulation of organ morphogenesis GO:2000027 35 0.478
cellular nitrogen compound metabolic process GO:0034641 290 0.478
Zebrafish
autonomic nervous system development GO:0048483 19 0.472
Zebrafish Mouse
hindbrain development GO:0030902 91 0.455
Zebrafish Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.446
mesoderm morphogenesis GO:0048332 51 0.445
brain development GO:0007420 293 0.441
Zebrafish Mouse
rhombomere boundary formation GO:0021654 10 0.433
nucleobase containing compound metabolic process GO:0006139 274 0.429
Zebrafish
regulation of signaling GO:0023051 235 0.429
transcription from rna polymerase ii promoter GO:0006366 80 0.427
Zebrafish
forebrain anterior posterior pattern specification GO:0021797 3 0.427
rna metabolic process GO:0016070 219 0.415
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.411
posterior lateral line neuromast primordium migration GO:0048920 12 0.409
axon guidance GO:0007411 86 0.402
nucleic acid metabolic process GO:0090304 244 0.398
Zebrafish
endocrine system development GO:0035270 65 0.397
transcription dna templated GO:0006351 181 0.396
Zebrafish
axonogenesis GO:0007409 152 0.384
regulation of nitrogen compound metabolic process GO:0051171 251 0.378
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.377
macromolecule biosynthetic process GO:0009059 227 0.375
Zebrafish
localization of cell GO:0051674 244 0.370
Zebrafish
oligodendrocyte cell fate specification GO:0021778 4 0.349
neuron projection development GO:0031175 180 0.343
chemotaxis GO:0006935 104 0.337
cellular aromatic compound metabolic process GO:0006725 295 0.333
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.331
cell morphogenesis involved in differentiation GO:0000904 195 0.328
blood vessel development GO:0001568 246 0.323
neuron development GO:0048666 262 0.323
taxis GO:0042330 109 0.321
regulation of biological quality GO:0065008 263 0.315
regulation of embryonic development GO:0045995 47 0.315
cell surface receptor signaling pathway GO:0007166 325 0.313
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.311
larval development GO:0002164 2 0.309
cell projection organization GO:0030030 284 0.301
regulation of metabolic process GO:0019222 359 0.297
Zebrafish
mesoderm development GO:0007498 88 0.296
pectoral fin development GO:0033339 50 0.295
heterocycle metabolic process GO:0046483 290 0.286
Zebrafish
negative regulation of neuron differentiation GO:0045665 10 0.285
epithelial tube morphogenesis GO:0060562 148 0.283
Zebrafish
axon development GO:0061564 166 0.279
regulation of gene expression GO:0010468 265 0.278
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.278
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.274
Mouse
neural tube development GO:0021915 62 0.273
Zebrafish
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.272
adult behavior GO:0030534 2 0.271
enzyme linked receptor protein signaling pathway GO:0007167 106 0.267
nucleobase containing compound biosynthetic process GO:0034654 205 0.267
Zebrafish
cell fate specification involved in pattern specification GO:0060573 3 0.264
appendage development GO:0048736 80 0.252
neural crest formation GO:0014029 14 0.252
regulation of neurogenesis GO:0050767 87 0.250
regulation of vasculogenesis GO:2001212 1 0.247
embryonic pectoral fin morphogenesis GO:0035118 24 0.246
cell morphogenesis GO:0000902 289 0.245
sensory neuron axon guidance GO:0097374 3 0.245
positive regulation of biological process GO:0048518 253 0.244
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.243
Zebrafish
intracellular receptor signaling pathway GO:0030522 30 0.242
neuron differentiation GO:0030182 353 0.242
stem cell differentiation GO:0048863 117 0.238
ventral spinal cord interneuron fate commitment GO:0060579 3 0.237
neuron projection morphogenesis GO:0048812 161 0.235
fin development GO:0033333 77 0.234
positive regulation of notch signaling pathway GO:0045747 3 0.231
ventricular system development GO:0021591 12 0.231
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.231
regulation of stem cell proliferation GO:0072091 2 0.228
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.228
Zebrafish
cell projection morphogenesis GO:0048858 244 0.226
regulation of macromolecule metabolic process GO:0060255 317 0.225
Zebrafish
cellular component morphogenesis GO:0032989 336 0.222
mechanosensory lateral line system development GO:0048881 49 0.216
neuron fate determination GO:0048664 2 0.215
fourth ventricle development GO:0021592 8 0.215
Zebrafish
neuromast primordium migration GO:0048883 12 0.214
negative regulation of axon regeneration GO:0048681 4 0.214
posterior lateral line development GO:0048916 38 0.213
morphogenesis of a branching structure GO:0001763 21 0.209
cellular response to retinoic acid GO:0071300 1 0.204
digestive tract development GO:0048565 265 0.202
negative regulation of biological process GO:0048519 304 0.202
dendrite guidance GO:0070983 0 0.196
head development GO:0060322 303 0.194
Zebrafish Mouse Fly
establishment of localization GO:0051234 244 0.193
Zebrafish
negative regulation of collateral sprouting GO:0048671 2 0.193
facial nerve morphogenesis GO:0021610 1 0.193
Mouse
type b pancreatic cell development GO:0003323 4 0.192
otic vesicle development GO:0071599 42 0.191
Zebrafish
regulation of cell development GO:0060284 100 0.189
regulation of gastrulation GO:0010470 24 0.189
regulation of neuron differentiation GO:0045664 56 0.184
pancreas development GO:0031016 84 0.182
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.179
rostrocaudal neural tube patterning GO:0021903 29 0.178
regulation of nucleic acid templated transcription GO:1903506 213 0.173
Zebrafish
artery development GO:0060840 22 0.170
negative regulation of neurogenesis GO:0050768 20 0.167
facial nucleus development GO:0021754 7 0.166
Zebrafish
patterning of blood vessels GO:0001569 15 0.165
regulation of endodermal cell fate specification GO:0042663 15 0.165
synaptic target recognition GO:0008039 1 0.164
mesenchyme development GO:0060485 127 0.164
branching morphogenesis of an epithelial tube GO:0048754 15 0.162
negative regulation of cell communication GO:0010648 96 0.160
heart development GO:0007507 313 0.157
cellular biosynthetic process GO:0044249 286 0.154
Zebrafish
epithelial cell differentiation GO:0030855 116 0.154
cranial nerve morphogenesis GO:0021602 15 0.152
Mouse
anatomical structure arrangement GO:0048532 2 0.151
Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.150
biosynthetic process GO:0009058 294 0.149
Zebrafish
neural crest cell differentiation GO:0014033 72 0.149
forebrain neuron development GO:0021884 7 0.148
ventral spinal cord interneuron specification GO:0021521 3 0.148
retinal ganglion cell axon guidance GO:0031290 35 0.147
nucleic acid templated transcription GO:0097659 181 0.147
Zebrafish
otic vesicle formation GO:0030916 27 0.146
mesodermal cell differentiation GO:0048333 21 0.145
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.144
Zebrafish
specification of symmetry GO:0009799 204 0.143
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.142
formation of anatomical boundary GO:0048859 14 0.141
lateral line development GO:0048882 66 0.138
regulation of nervous system development GO:0051960 90 0.136
otic placode formation GO:0043049 23 0.134
morphogenesis of an epithelium GO:0002009 333 0.133
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.132
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.132
Zebrafish
hindbrain morphogenesis GO:0021575 22 0.130
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.129
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.129
eye development GO:0001654 277 0.128
sensory organ morphogenesis GO:0090596 200 0.127
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.127
Zebrafish
endocrine pancreas development GO:0031018 27 0.126
response to external stimulus GO:0009605 264 0.123
aromatic compound biosynthetic process GO:0019438 217 0.116
Zebrafish
negative regulation of signaling GO:0023057 96 0.116
oocyte maturation GO:0001556 4 0.115
glial cell fate specification GO:0021780 4 0.115
hypochord development GO:0055016 3 0.114
neuron fate specification GO:0048665 20 0.112
angiogenesis GO:0001525 158 0.112
positive regulation of translation GO:0045727 1 0.112
negative regulation of cellular process GO:0048523 283 0.111
regulation of signal transduction GO:0009966 225 0.111
cartilage development GO:0051216 96 0.110
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.109
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.108
regulation of macromolecule biosynthetic process GO:0010556 225 0.107
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.107
Zebrafish
mesodermal cell fate commitment GO:0001710 14 0.107
developmental growth involved in morphogenesis GO:0060560 86 0.106
regulation of rna metabolic process GO:0051252 224 0.106
Zebrafish
aging GO:0007568 2 0.104
regulation of rna biosynthetic process GO:2001141 213 0.102
Zebrafish
negative regulation of cell differentiation GO:0045596 46 0.102
regulation of cell fate commitment GO:0010453 22 0.100
floor plate development GO:0033504 15 0.099
gland development GO:0048732 143 0.097
exocrine system development GO:0035272 28 0.096
regulation of mesodermal cell fate specification GO:0042661 9 0.095
cell proliferation GO:0008283 80 0.094
mesenchymal cell differentiation GO:0048762 87 0.093
neuromast mantle cell differentiation GO:0048888 1 0.092
regulation of biosynthetic process GO:0009889 250 0.091
Zebrafish
muscle structure development GO:0061061 196 0.090
nephron morphogenesis GO:0072028 2 0.090
negative regulation of neuron projection regeneration GO:0070571 4 0.090
skin development GO:0043588 54 0.088
neural tube formation GO:0001841 16 0.087
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.087
digestive tract morphogenesis GO:0048546 231 0.086
regulation of inner ear receptor cell differentiation GO:2000980 1 0.086
parasympathetic nervous system development GO:0048486 6 0.085
Zebrafish Mouse
positive regulation of nervous system development GO:0051962 25 0.083
positive regulation of nucleic acid templated transcription GO:1903508 57 0.083
Zebrafish
regulation of cardiac chamber formation GO:1901210 2 0.082
cell proliferation in hindbrain GO:0021534 4 0.082
retinal cone cell differentiation GO:0042670 12 0.078
post anal tail morphogenesis GO:0036342 19 0.078
nephron epithelium morphogenesis GO:0072088 1 0.078
rna biosynthetic process GO:0032774 181 0.078
Zebrafish
myeloid cell differentiation GO:0030099 86 0.078
gene expression GO:0010467 252 0.077
Zebrafish
skeletal muscle organ development GO:0060538 78 0.076
single organism metabolic process GO:0044710 217 0.076
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.075
neuroblast fate commitment GO:0014017 1 0.074
organic substance biosynthetic process GO:1901576 289 0.073
Zebrafish
protein metabolic process GO:0019538 183 0.072
post embryonic organ development GO:0048569 4 0.072
negative regulation of developmental process GO:0051093 65 0.072
leukocyte differentiation GO:0002521 25 0.071
growth plate cartilage development GO:0003417 2 0.071
sympathetic ganglion development GO:0061549 2 0.070
central nervous system segmentation GO:0035283 6 0.069
cellular response to organic substance GO:0071310 105 0.069
positive regulation of response to stimulus GO:0048584 80 0.069
vasculature development GO:0001944 278 0.069
peripheral nervous system development GO:0007422 55 0.068
aorta development GO:0035904 4 0.068
single organism organelle organization GO:1902589 199 0.067
Zebrafish
embryonic appendage morphogenesis GO:0035113 30 0.067
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.066
negative regulation of nervous system development GO:0051961 22 0.066
angioblast cell migration GO:0035476 9 0.065
pectoral fin morphogenesis GO:0035138 29 0.065
lateral line system development GO:0048925 76 0.065
somite development GO:0061053 96 0.064
auditory receptor cell fate commitment GO:0009912 4 0.064
epidermal cell differentiation GO:0009913 36 0.064
patterning of lymph vessels GO:0060854 1 0.063
kidney development GO:0001822 92 0.062
mesenchymal cell development GO:0014031 78 0.062
negative regulation of signal transduction GO:0009968 94 0.062
cell part morphogenesis GO:0032990 246 0.061
myotome development GO:0061055 1 0.060
positive regulation of cellular biosynthetic process GO:0031328 68 0.060
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.059
stem cell proliferation GO:0072089 4 0.059
muscle cell differentiation GO:0042692 139 0.059
eye morphogenesis GO:0048592 144 0.059
sensory system development GO:0048880 76 0.059
regulation of tube size GO:0035150 2 0.058
negative regulation of gene expression GO:0010629 65 0.057
rhombomere 5 morphogenesis GO:0021664 1 0.057
establishment of spindle localization GO:0051293 12 0.057
Zebrafish
distal tubule development GO:0072017 1 0.057
regulation of mesoderm development GO:2000380 11 0.055
central nervous system neuron differentiation GO:0021953 74 0.055
nephron epithelium development GO:0072009 16 0.055
positive regulation of macromolecule metabolic process GO:0010604 93 0.055
Zebrafish
venous blood vessel development GO:0060841 9 0.054
immune system development GO:0002520 191 0.054
epidermis development GO:0008544 48 0.054
sympathetic nervous system development GO:0048485 3 0.053
positive regulation of developmental process GO:0051094 50 0.053
nephric duct development GO:0072176 13 0.053
kidney epithelium development GO:0072073 23 0.052
vasculogenesis GO:0001570 41 0.052
endodermal cell fate specification GO:0001714 17 0.052
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.051
regulation of transcription dna templated GO:0006355 213 0.051
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 55 0.051
photoreceptor cell fate specification GO:0043704 1 0.051
regeneration GO:0031099 91 0.050
inner ear receptor cell fate commitment GO:0060120 4 0.050
cellular response to chemical stimulus GO:0070887 157 0.050
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.050
apoptotic process involved in morphogenesis GO:0060561 2 0.049
maintenance of location GO:0051235 4 0.049
neural crest cell fate specification GO:0014036 5 0.049
neural retina development GO:0003407 49 0.049
proximal distal pattern formation GO:0009954 1 0.048
stem cell fate commitment GO:0048865 1 0.048
nerve development GO:0021675 45 0.048
Zebrafish Mouse
heterocycle biosynthetic process GO:0018130 215 0.048
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.048
Zebrafish
morphogenesis of a branching epithelium GO:0061138 16 0.047
developmental growth GO:0048589 166 0.047
otic vesicle morphogenesis GO:0071600 34 0.046
regulation of myotube differentiation GO:0010830 2 0.046
neuron projection extension GO:1990138 45 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
Zebrafish
behavior GO:0007610 74 0.045
cell differentiation involved in kidney development GO:0061005 13 0.044
determination of heart left right asymmetry GO:0061371 117 0.044
cell proliferation in forebrain GO:0021846 3 0.044
hemopoiesis GO:0030097 183 0.044
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.044
regulation of cardiac chamber morphogenesis GO:1901219 2 0.043
positive regulation of neural precursor cell proliferation GO:2000179 1 0.043
negative regulation of nucleic acid templated transcription GO:1903507 45 0.043
positive regulation of cell activation GO:0050867 1 0.043
posterior lateral line system development GO:0048915 46 0.043
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.042
embryonic epithelial tube formation GO:0001838 17 0.042
Zebrafish
midbrain hindbrain boundary development GO:0030917 23 0.042
eye photoreceptor cell development GO:0042462 30 0.042
negative regulation of axon guidance GO:1902668 1 0.041
macromolecular complex subunit organization GO:0043933 74 0.041
Zebrafish
multi organism reproductive process GO:0044703 36 0.041
bmp signaling pathway GO:0030509 52 0.041
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.041
response to chemical GO:0042221 320 0.040
cellular localization GO:0051641 97 0.040
Zebrafish
rhombomere 5 development GO:0021571 4 0.040
neuron projection regeneration GO:0031102 16 0.040
mesoderm formation GO:0001707 43 0.040
abducens nucleus development GO:0021742 2 0.040
negative regulation of myeloid cell differentiation GO:0045638 1 0.040
regulation of axon extension GO:0030516 24 0.039
regulation of vasculature development GO:1901342 33 0.039
nephron development GO:0072006 31 0.039
locomotory behavior GO:0007626 34 0.039
compound eye development GO:0048749 2 0.039
neuromast hair cell differentiation GO:0048886 12 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.038
organic acid metabolic process GO:0006082 31 0.038
artery morphogenesis GO:0048844 14 0.038
negative regulation of macromolecule metabolic process GO:0010605 76 0.038
positive regulation of biosynthetic process GO:0009891 68 0.038
Zebrafish
gastrulation GO:0007369 208 0.038
cell cell recognition GO:0009988 1 0.037
ectodermal placode formation GO:0060788 26 0.037
lipid storage GO:0019915 1 0.037
nephron tubule morphogenesis GO:0072078 1 0.037
positive regulation of protein kinase b signaling GO:0051897 1 0.037
brain segmentation GO:0035284 6 0.036
anterior commissure morphogenesis GO:0021960 3 0.036
connective tissue development GO:0061448 99 0.036
positive regulation of cell cycle GO:0045787 3 0.036
ameboidal type cell migration GO:0001667 143 0.036
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
Zebrafish
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.035
aorta morphogenesis GO:0035909 3 0.035
positive regulation of rna biosynthetic process GO:1902680 57 0.034
Zebrafish
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.034
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.034
regulation of localization GO:0032879 104 0.034
apoptotic process GO:0006915 116 0.034
positive regulation of transcription dna templated GO:0045893 57 0.034
Zebrafish
negative chemotaxis GO:0050919 1 0.034
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.034
auditory receptor cell fate determination GO:0042668 2 0.033
ventral spinal cord interneuron differentiation GO:0021514 12 0.033
endochondral bone growth GO:0003416 2 0.033
glandular epithelial cell differentiation GO:0002067 9 0.033
sensory organ development GO:0007423 393 0.032
Zebrafish
camera type eye photoreceptor cell differentiation GO:0060219 19 0.032
kidney morphogenesis GO:0060993 15 0.032
multicellular organism growth GO:0035264 4 0.032
positive regulation of molecular function GO:0044093 33 0.032
nucleocytoplasmic transport GO:0006913 4 0.031
muscle tissue development GO:0060537 110 0.031
peripheral nervous system neuron axonogenesis GO:0048936 13 0.031
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.031
cell cycle g1 s phase transition GO:0044843 1 0.031
formation of primary germ layer GO:0001704 62 0.031
leukocyte migration GO:0050900 15 0.031
somitogenesis GO:0001756 87 0.030
response to organic substance GO:0010033 153 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.030
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.030
cartilage morphogenesis GO:0060536 13 0.030
water homeostasis GO:0030104 4 0.029
negative regulation of cell development GO:0010721 26 0.029
apoptotic process involved in development GO:1902742 2 0.029
stem cell development GO:0048864 82 0.029
regulation of cellular protein metabolic process GO:0032268 52 0.029
intracellular estrogen receptor signaling pathway GO:0030520 3 0.029
epithelial cell morphogenesis GO:0003382 2 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.029
positive regulation of axon guidance GO:1902669 1 0.029
negative regulation of metabolic process GO:0009892 86 0.029
cellular protein modification process GO:0006464 100 0.028
neural crest cell development GO:0014032 62 0.028
sensory perception of pain GO:0019233 1 0.028
endodermal cell fate determination GO:0007493 2 0.028
immune response GO:0006955 28 0.028
small molecule metabolic process GO:0044281 77 0.028
pancreatic d cell differentiation GO:0003311 2 0.028
cardiac chamber formation GO:0003207 4 0.028
dorsal spinal cord development GO:0021516 1 0.028
negative regulation of axon extension GO:0030517 7 0.027
g1 s transition of mitotic cell cycle GO:0000082 1 0.027
spinal cord association neuron differentiation GO:0021527 1 0.027
positive regulation of apoptotic process GO:0043065 29 0.027
regulation of cell proliferation GO:0042127 37 0.027
positive regulation of cell development GO:0010720 25 0.026
muscle cell development GO:0055001 115 0.026
negative regulation of cell projection organization GO:0031345 9 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
negative regulation of reproductive process GO:2000242 3 0.026
establishment of cell polarity GO:0030010 18 0.025
Zebrafish
segmentation GO:0035282 97 0.025
Fly
pharyngeal system development GO:0060037 18 0.025
forebrain regionalization GO:0021871 4 0.025
forebrain cell migration GO:0021885 1 0.025
posttranscriptional regulation of gene expression GO:0010608 14 0.025
regulation of angiogenesis GO:0045765 26 0.025
epithelial cell development GO:0002064 42 0.025
regulation of protein metabolic process GO:0051246 56 0.025
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.024
positive regulation of cellular protein metabolic process GO:0032270 22 0.024
tube formation GO:0035148 25 0.024
Zebrafish
mediolateral intercalation GO:0060031 3 0.024
ear morphogenesis GO:0042471 64 0.024
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.023
auditory receptor cell fate specification GO:0042667 2 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
protein modification process GO:0036211 100 0.023
spinal cord anterior posterior patterning GO:0021512 1 0.023
embryonic limb morphogenesis GO:0030326 2 0.023
specification of organ position GO:0010159 3 0.023
positive regulation of signaling GO:0023056 56 0.023
pons development GO:0021548 11 0.022
Zebrafish
positive regulation of protein metabolic process GO:0051247 23 0.022
positive regulation of stem cell proliferation GO:2000648 1 0.022
regulation of neuron projection development GO:0010975 40 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
embryonic heart tube development GO:0035050 133 0.022
convergent extension involved in organogenesis GO:0060029 10 0.022
forebrain development GO:0030900 96 0.022
morphogenesis of embryonic epithelium GO:0016331 30 0.022
Zebrafish
ectodermal placode development GO:0071696 37 0.022
regulation of mechanoreceptor differentiation GO:0045631 1 0.022
photoreceptor cell differentiation GO:0046530 55 0.022
pancreatic a cell development GO:0003322 2 0.022
regulation of endodermal cell differentiation GO:1903224 15 0.022
stem cell fate determination GO:0048867 1 0.022
kidney rudiment formation GO:0072003 3 0.022
cellular protein metabolic process GO:0044267 129 0.022
regulation of canonical wnt signaling pathway GO:0060828 34 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
growth GO:0040007 174 0.021
type b pancreatic cell differentiation GO:0003309 8 0.021
negative regulation of stem cell differentiation GO:2000737 2 0.021
outflow tract morphogenesis GO:0003151 1 0.021
body morphogenesis GO:0010171 16 0.021
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.021
regulation of wnt signaling pathway GO:0030111 53 0.021
branchiomotor neuron axon guidance GO:0021785 1 0.021
exocrine pancreas development GO:0031017 28 0.021
retina development in camera type eye GO:0060041 146 0.021
macromolecule modification GO:0043412 111 0.021
secondary metabolic process GO:0019748 3 0.021
spinal cord patterning GO:0021511 6 0.020
renal tubule development GO:0061326 5 0.020
translational initiation GO:0006413 3 0.020
central nervous system myelination GO:0022010 2 0.020

hoxb2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
charcot marie tooth disease type 4 DOID:0050541 0 0.074
neuromuscular disease DOID:440 0 0.074
disease of anatomical entity DOID:7 0 0.074
charcot marie tooth disease DOID:10595 0 0.074
nervous system disease DOID:863 0 0.074
neuropathy DOID:870 0 0.074