Danio rerio

0 known processes

hsd17b2

hydroxysteroid (17-beta) dehydrogenase 2

hsd17b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.267
response to metal ion GO:0010038 34 0.259
Rat
response to ketone GO:1901654 1 0.243
response to nutrient GO:0007584 3 0.198
organophosphate biosynthetic process GO:0090407 23 0.172
cellular component morphogenesis GO:0032989 336 0.153
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.141
regulation of response to stimulus GO:0048583 269 0.132
positive regulation of cell killing GO:0031343 2 0.126
homeostatic process GO:0042592 142 0.124
response to chemical GO:0042221 320 0.123
Human Rat
cell morphogenesis involved in differentiation GO:0000904 195 0.114
nucleotide biosynthetic process GO:0009165 21 0.112
head development GO:0060322 303 0.109
nucleocytoplasmic transport GO:0006913 4 0.101
response to monosaccharide GO:0034284 3 0.097
oxoacid metabolic process GO:0043436 31 0.094
cell projection morphogenesis GO:0048858 244 0.090
nuclear import GO:0051170 3 0.088
central nervous system development GO:0007417 387 0.087
aging GO:0007568 2 0.083
regulation of cellular amine metabolic process GO:0033238 0 0.081
response to drug GO:0042493 3 0.080
regulation of metabolic process GO:0019222 359 0.077
long chain fatty acid metabolic process GO:0001676 1 0.076
cellular nitrogen compound metabolic process GO:0034641 290 0.076
response to endogenous stimulus GO:0009719 83 0.075
cellular macromolecule metabolic process GO:0044260 391 0.075
response to nitrogen compound GO:1901698 19 0.074
digestive system development GO:0055123 289 0.072
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.072
biosynthetic process GO:0009058 294 0.072
Zebrafish Rat
response to vitamin GO:0033273 3 0.071
purine containing compound biosynthetic process GO:0072522 20 0.069
response to organic substance GO:0010033 153 0.068
Human
response to corticosteroid GO:0031960 1 0.067
neurological system process GO:0050877 62 0.067
positive regulation of metabolic process GO:0009893 108 0.067
sensory organ development GO:0007423 393 0.066
Zebrafish
regulation of biological quality GO:0065008 263 0.064
Zebrafish Rat
maintenance of location GO:0051235 4 0.064
mononuclear cell proliferation GO:0032943 1 0.064
lipid storage GO:0019915 1 0.063
protein acetylation GO:0006473 2 0.061
generation of neurons GO:0048699 385 0.061
Zebrafish
phosphorus metabolic process GO:0006793 109 0.060
organonitrogen compound biosynthetic process GO:1901566 47 0.059
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.059
response to biotic stimulus GO:0009607 97 0.057
amine metabolic process GO:0009308 2 0.057
heterocycle biosynthetic process GO:0018130 215 0.057
compound eye development GO:0048749 2 0.057
organophosphate metabolic process GO:0019637 37 0.057
ribonucleoside monophosphate catabolic process GO:0009158 4 0.056
cellular response to nutrient levels GO:0031669 2 0.056
embryonic cranial skeleton morphogenesis GO:0048701 90 0.056
response to external stimulus GO:0009605 264 0.055
response to stress GO:0006950 263 0.055
Zebrafish
cellular amine metabolic process GO:0044106 2 0.055
nuclear transport GO:0051169 4 0.055
purine nucleotide biosynthetic process GO:0006164 20 0.054
response to hormone GO:0009725 48 0.054
protein import into nucleus GO:0006606 3 0.054
tube morphogenesis GO:0035239 349 0.053
Zebrafish
behavior GO:0007610 74 0.053
cell morphogenesis GO:0000902 289 0.052
response to other organism GO:0051707 97 0.051
response to cadmium ion GO:0046686 14 0.051
mesenchyme development GO:0060485 127 0.051
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.050
Zebrafish Rat
lymphocyte mediated immunity GO:0002449 5 0.050
ear development GO:0043583 127 0.050
autophagy GO:0006914 4 0.049
dopamine metabolic process GO:0042417 2 0.049
cell part morphogenesis GO:0032990 246 0.049
adult behavior GO:0030534 2 0.049
protein localization to nucleus GO:0034504 3 0.048
organonitrogen compound metabolic process GO:1901564 74 0.048
xenobiotic metabolic process GO:0006805 4 0.048
aromatic compound biosynthetic process GO:0019438 217 0.048
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.048
nitrogen compound metabolic process GO:0006807 319 0.047
regulation of cellular metabolic process GO:0031323 320 0.047
cellular response to organic cyclic compound GO:0071407 38 0.047
inner ear development GO:0048839 126 0.047
small molecule metabolic process GO:0044281 77 0.046
Zebrafish
response to carbohydrate GO:0009743 3 0.046
cellular response to external stimulus GO:0071496 2 0.045
eye development GO:0001654 277 0.045
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Mouse
signal transduction GO:0007165 455 0.045
positive regulation of biological process GO:0048518 253 0.044
single organism nuclear import GO:1902593 3 0.044
embryonic skeletal system development GO:0048706 97 0.044
lymphocyte proliferation GO:0046651 1 0.044
regulation of protein targeting GO:1903533 2 0.044
sensory system development GO:0048880 76 0.043
carbohydrate derivative biosynthetic process GO:1901137 43 0.043
response to abiotic stimulus GO:0009628 122 0.043
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.043
cell killing GO:0001906 2 0.042
response to amine GO:0014075 1 0.042
embryonic skeletal system morphogenesis GO:0048704 93 0.042
protein targeting to nucleus GO:0044744 3 0.041
muscle structure development GO:0061061 196 0.041
positive regulation of immune effector process GO:0002699 3 0.041
nucleoside monophosphate catabolic process GO:0009125 4 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
regulation of cellular ketone metabolic process GO:0010565 7 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
organic cyclic compound biosynthetic process GO:1901362 223 0.040
Rat
g protein coupled receptor signaling pathway GO:0007186 74 0.040
chordate embryonic development GO:0043009 271 0.040
Mouse
internal protein amino acid acetylation GO:0006475 2 0.040
response to bacterium GO:0009617 58 0.040
response to glucocorticoid GO:0051384 1 0.040
protein import GO:0017038 3 0.040
stem cell proliferation GO:0072089 4 0.039
cellular ketone metabolic process GO:0042180 11 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.038
cellular component biogenesis GO:0044085 178 0.038
neuron development GO:0048666 262 0.037
purine nucleoside monophosphate catabolic process GO:0009128 4 0.036
carboxylic acid metabolic process GO:0019752 22 0.035
defense response GO:0006952 47 0.035
striated muscle tissue development GO:0014706 110 0.035
hemopoiesis GO:0030097 183 0.035
neuron differentiation GO:0030182 353 0.034
Zebrafish
response to antibiotic GO:0046677 1 0.034
neuron projection development GO:0031175 180 0.034
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
single organism metabolic process GO:0044710 217 0.034
Human Zebrafish Rat
phosphate containing compound metabolic process GO:0006796 108 0.034
regulation of nucleocytoplasmic transport GO:0046822 2 0.034
cellular component assembly GO:0022607 170 0.034
protein metabolic process GO:0019538 183 0.033
digestive tract development GO:0048565 265 0.033
Zebrafish
negative regulation of cellular process GO:0048523 283 0.033
cellular response to extracellular stimulus GO:0031668 2 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.032
guanosine containing compound catabolic process GO:1901069 2 0.032
camera type eye development GO:0043010 222 0.032
Zebrafish
regulation of protein ubiquitination GO:0031396 3 0.032
cytoskeleton dependent cytokinesis GO:0061640 3 0.032
negative regulation of protein kinase activity GO:0006469 4 0.031
positive regulation of cell cycle GO:0045787 3 0.031
organic acid metabolic process GO:0006082 31 0.031
transport GO:0006810 220 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
positive regulation of camp biosynthetic process GO:0030819 2 0.030
digestive tract morphogenesis GO:0048546 231 0.030
Zebrafish
regulation of response to nutrient levels GO:0032107 1 0.030
system process GO:0003008 185 0.030
Zebrafish
brain development GO:0007420 293 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.029
stem cell division GO:0017145 1 0.029
establishment of protein localization to plasma membrane GO:0090002 1 0.029
regulation of inflammatory response GO:0050727 2 0.029
negative regulation of catabolic process GO:0009895 3 0.029
cell projection organization GO:0030030 284 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
cellular protein metabolic process GO:0044267 129 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
positive regulation of transport GO:0051050 2 0.028
regulation of molecular function GO:0065009 70 0.028
establishment of localization in cell GO:0051649 77 0.028
single organism localization GO:1902578 225 0.028
immune system process GO:0002376 241 0.027
catechol containing compound metabolic process GO:0009712 2 0.027
positive regulation of leukocyte mediated immunity GO:0002705 1 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.027
retina homeostasis GO:0001895 12 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.027
nucleoside phosphate biosynthetic process GO:1901293 21 0.027
neuron projection morphogenesis GO:0048812 161 0.027
locomotion GO:0040011 313 0.027
chemical homeostasis GO:0048878 49 0.027
leukocyte activation GO:0045321 12 0.027
fertilization GO:0009566 3 0.026
positive regulation of cell activation GO:0050867 1 0.026
single organism biosynthetic process GO:0044711 71 0.026
Zebrafish Rat
regulation of cell development GO:0060284 100 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
Rat
blood vessel development GO:0001568 246 0.026
determination of left right symmetry GO:0007368 179 0.026
Zebrafish
gene expression GO:0010467 252 0.025
axonogenesis GO:0007409 152 0.025
gtp metabolic process GO:0046039 4 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
cognition GO:0050890 1 0.025
cellular response to starvation GO:0009267 1 0.025
leukocyte proliferation GO:0070661 1 0.025
cellular aldehyde metabolic process GO:0006081 4 0.025
Zebrafish
alcohol biosynthetic process GO:0046165 2 0.025
cilium morphogenesis GO:0060271 85 0.025
gastrulation GO:0007369 208 0.025
forebrain development GO:0030900 96 0.025
sensory perception of chemical stimulus GO:0007606 3 0.024
heart development GO:0007507 313 0.024
Zebrafish
energy reserve metabolic process GO:0006112 2 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
ion homeostasis GO:0050801 41 0.024
wound healing GO:0042060 90 0.024
single organism transport GO:0044765 206 0.024
cellular response to organic substance GO:0071310 105 0.024
tissue homeostasis GO:0001894 25 0.024
response to inorganic substance GO:0010035 38 0.023
Rat
protein homooligomerization GO:0051260 3 0.023
toll like receptor signaling pathway GO:0002224 4 0.023
regulation of synapse organization GO:0050807 3 0.023
cellular component movement GO:0006928 335 0.023
cell substrate adhesion GO:0031589 4 0.023
retina development in camera type eye GO:0060041 146 0.023
Zebrafish
regulation of protein transport GO:0051223 3 0.023
response to steroid hormone GO:0048545 35 0.023
otolith development GO:0048840 32 0.023
estrogen metabolic process GO:0008210 2 0.023
Rat
regulation of developmental process GO:0050793 247 0.023
gtp catabolic process GO:0006184 2 0.023
cellular localization GO:0051641 97 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
cytokinesis GO:0000910 3 0.023
nucleoside biosynthetic process GO:0009163 2 0.023
fin development GO:0033333 77 0.022
Zebrafish
regulation of apoptotic process GO:0042981 98 0.022
regulation of catalytic activity GO:0050790 55 0.022
response to wounding GO:0009611 116 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
response to amphetamine GO:0001975 1 0.022
response to external biotic stimulus GO:0043207 97 0.022
organelle fusion GO:0048284 3 0.022
post embryonic organ development GO:0048569 4 0.021
regulation of cell activation GO:0050865 1 0.021
cellular response to lipopolysaccharide GO:0071222 3 0.021
cell migration GO:0016477 237 0.021
regulation of cell killing GO:0031341 2 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
nuclear migration GO:0007097 3 0.021
negative regulation of striated muscle tissue development GO:0045843 2 0.021
endosomal transport GO:0016197 2 0.021
regulation of cell death GO:0010941 103 0.021
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.021
phagocytosis GO:0006909 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
response to hexose GO:0009746 3 0.021
multicellular organism growth GO:0035264 4 0.021
cellular biosynthetic process GO:0044249 286 0.021
Zebrafish Rat
lipid catabolic process GO:0016042 4 0.020
golgi vesicle transport GO:0048193 3 0.020
regulation of calcium ion transport GO:0051924 2 0.020
regulation of metal ion transport GO:0010959 4 0.020
cilium movement GO:0003341 26 0.020
lipid homeostasis GO:0055088 3 0.020
negative regulation of muscle tissue development GO:1901862 2 0.020
macroautophagy GO:0016236 1 0.020
centrosome organization GO:0051297 1 0.020
stem cell maintenance GO:0019827 4 0.020
translational initiation GO:0006413 3 0.020
protein acylation GO:0043543 3 0.020
negative regulation of kinase activity GO:0033673 4 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
regulation of carbohydrate metabolic process GO:0006109 4 0.020
response to alkaloid GO:0043279 2 0.020
internal peptidyl lysine acetylation GO:0018393 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
nucleobase containing small molecule metabolic process GO:0055086 32 0.020
chemosensory behavior GO:0007635 1 0.020
purine ribonucleoside biosynthetic process GO:0046129 2 0.020
regulation of binding GO:0051098 3 0.019
female sex differentiation GO:0046660 4 0.019
regulation of reproductive process GO:2000241 4 0.019
programmed cell death GO:0012501 119 0.019
carbohydrate biosynthetic process GO:0016051 1 0.019
cellular lipid metabolic process GO:0044255 36 0.019
Zebrafish
response to topologically incorrect protein GO:0035966 2 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
protein secretion GO:0009306 1 0.019
hatching GO:0035188 4 0.019
iron ion homeostasis GO:0055072 4 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
response to organic cyclic compound GO:0014070 51 0.019
regulation of transporter activity GO:0032409 2 0.018
localization of cell GO:0051674 244 0.018
response to oxygen containing compound GO:1901700 55 0.018
Human
peptide transport GO:0015833 1 0.018
lymph vessel morphogenesis GO:0036303 25 0.018
regulation of synapse assembly GO:0051963 3 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
heterocycle metabolic process GO:0046483 290 0.018
lymphocyte activation GO:0046649 10 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
response to glucose GO:0009749 3 0.018
skeletal system development GO:0001501 181 0.018
Zebrafish Rat
embryonic organ morphogenesis GO:0048562 274 0.018
Zebrafish
macromolecule modification GO:0043412 111 0.018
response to activity GO:0014823 14 0.018
somatic muscle development GO:0007525 4 0.018
regulation of dendrite development GO:0050773 3 0.018
negative regulation of reproductive process GO:2000242 3 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
nucleic acid templated transcription GO:0097659 181 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
t cell mediated immunity GO:0002456 1 0.018
regulation of blood vessel size GO:0050880 2 0.018
anatomical structure homeostasis GO:0060249 36 0.018
action potential GO:0001508 19 0.018
lateral line development GO:0048882 66 0.018
regulation of protein localization to plasma membrane GO:1903076 1 0.017
transcription dna templated GO:0006351 181 0.017
neuronal action potential GO:0019228 18 0.017
activation of mapk activity GO:0000187 3 0.017
heart morphogenesis GO:0003007 156 0.017
Zebrafish
modification dependent protein catabolic process GO:0019941 3 0.017
photoreceptor cell morphogenesis GO:0008594 1 0.017
positive regulation of jnk cascade GO:0046330 3 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
b cell activation GO:0042113 2 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.017
positive regulation of stress activated mapk cascade GO:0032874 3 0.017
mrna catabolic process GO:0006402 6 0.017
centrosome cycle GO:0007098 1 0.017
histone modification GO:0016570 20 0.017
glucose homeostasis GO:0042593 1 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
angiogenesis GO:0001525 158 0.016
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.016
muscle organ development GO:0007517 101 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
response to lipid GO:0033993 60 0.016
Human
negative regulation of intracellular transport GO:0032387 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
regulation of cell shape GO:0008360 1 0.016
cellular pigmentation GO:0033059 30 0.016
positive regulation of biosynthetic process GO:0009891 68 0.016
cellular response to stress GO:0033554 62 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
death GO:0016265 121 0.016
cellular response to steroid hormone stimulus GO:0071383 31 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
negative regulation of intracellular protein transport GO:0090317 3 0.016
cell death GO:0008219 121 0.016
peptidyl serine modification GO:0018209 2 0.016
atp catabolic process GO:0006200 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
vasculature development GO:0001944 278 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
negative regulation of protein transport GO:0051224 3 0.016
carbohydrate homeostasis GO:0033500 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
rna metabolic process GO:0016070 219 0.015
regulation of programmed cell death GO:0043067 101 0.015
melanosome transport GO:0032402 19 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
establishment of endothelial barrier GO:0061028 3 0.015
actin mediated cell contraction GO:0070252 1 0.015
regulation of organelle assembly GO:1902115 4 0.015
hormone biosynthetic process GO:0042446 3 0.015
Rat
microtubule organizing center organization GO:0031023 1 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
fatty acid transport GO:0015908 1 0.015
response to acid chemical GO:0001101 17 0.015
Human
positive regulation of cytokine production GO:0001819 2 0.015
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
pigment granule localization GO:0051875 25 0.015
monocarboxylic acid metabolic process GO:0032787 17 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
cellular protein catabolic process GO:0044257 4 0.015
fat soluble vitamin metabolic process GO:0006775 4 0.015
Zebrafish
response to organonitrogen compound GO:0010243 12 0.015
multicellular organismal response to stress GO:0033555 2 0.014
Zebrafish
negative regulation of biological process GO:0048519 304 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
blood vessel morphogenesis GO:0048514 216 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
negative regulation of autophagy GO:0010507 1 0.014
ribose phosphate biosynthetic process GO:0046390 20 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
cell motility GO:0048870 244 0.014
b cell mediated immunity GO:0019724 3 0.014
nitric oxide biosynthetic process GO:0006809 2 0.014
stem cell differentiation GO:0048863 117 0.014
Zebrafish
dicarboxylic acid metabolic process GO:0043648 1 0.014
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.014
regulation of receptor activity GO:0010469 2 0.014
sphingolipid biosynthetic process GO:0030148 2 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
homeostasis of number of cells GO:0048872 62 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
sequestering of calcium ion GO:0051208 3 0.014
regulation of tube size GO:0035150 2 0.014
acylglycerol homeostasis GO:0055090 2 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
cytokinetic process GO:0032506 2 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
regulation of leukocyte mediated immunity GO:0002703 1 0.014
cellular lipid catabolic process GO:0044242 3 0.014
thermosensory behavior GO:0040040 1 0.014
sensory organ morphogenesis GO:0090596 200 0.014
Zebrafish
protein localization to plasma membrane GO:0072659 1 0.014
growth GO:0040007 174 0.014
positive regulation of camp metabolic process GO:0030816 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
immune system development GO:0002520 191 0.013
pigmentation GO:0043473 85 0.013
rho protein signal transduction GO:0007266 5 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
defense response to other organism GO:0098542 33 0.013
neural crest cell differentiation GO:0014033 72 0.013
Zebrafish
striated muscle cell development GO:0055002 108 0.013
muscle cell migration GO:0014812 4 0.013
negative regulation of translation GO:0017148 1 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
notch signaling pathway GO:0007219 35 0.013
multi organism cellular process GO:0044764 2 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.013
germ line stem cell maintenance GO:0030718 2 0.013
negative regulation of defense response GO:0031348 2 0.013
anterior posterior pattern specification GO:0009952 152 0.013
regulation of autophagy GO:0010506 3 0.013
establishment of localization GO:0051234 244 0.013
multicellular organismal homeostasis GO:0048871 29 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
response to alcohol GO:0097305 14 0.013
embryonic organ development GO:0048568 381 0.013
Zebrafish
cation homeostasis GO:0055080 33 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
regulation of cytokine production GO:0001817 3 0.013
axon ensheathment in central nervous system GO:0032291 2 0.013
regulation of signal transduction GO:0009966 225 0.013
defense response to bacterium GO:0042742 22 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
Zebrafish
regulation of blood coagulation GO:0030193 1 0.013
apoptotic process GO:0006915 116 0.013
cell substrate junction assembly GO:0007044 2 0.013
developmental cell growth GO:0048588 52 0.012
positive regulation of neural precursor cell proliferation GO:2000179 1 0.012
oxidation reduction process GO:0055114 41 0.012
Human Zebrafish Rat
aromatic compound catabolic process GO:0019439 15 0.012
metal ion homeostasis GO:0055065 26 0.012
exocytosis GO:0006887 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
meiotic nuclear division GO:0007126 4 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
protein modification process GO:0036211 100 0.012
secondary metabolic process GO:0019748 3 0.012
sensory perception of pain GO:0019233 1 0.012
positive regulation of reproductive process GO:2000243 2 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
regionalization GO:0003002 274 0.012
regulation of localization GO:0032879 104 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
multi organism process GO:0051704 134 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
response to estrogen GO:0043627 27 0.012
membrane hyperpolarization GO:0060081 1 0.012
toxin metabolic process GO:0009404 1 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
pericardium development GO:0060039 1 0.012
microtubule based movement GO:0007018 33 0.012
ion transmembrane transport GO:0034220 91 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
cell projection assembly GO:0030031 64 0.012

hsd17b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.055
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
inherited metabolic disorder DOID:655 0 0.032
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.028
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
heart disease DOID:114 0 0.021
cardiomyopathy DOID:0050700 0 0.021
intrinsic cardiomyopathy DOID:0060036 0 0.021
cardiovascular system disease DOID:1287 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021