Danio rerio

13 known processes

hsp90ab1

heat shock protein 90, alpha (cytosolic), class B member 1

(Aliases: hsp90beta,wu:gcd22h07,wu:fa91e11,wu:fa29f01,hsp90b,wu:fd59e11)

hsp90ab1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.477
Worm
translational initiation GO:0006413 3 0.204
positive regulation of translation GO:0045727 1 0.196
gene expression GO:0010467 252 0.163
Human
cell morphogenesis GO:0000902 289 0.163
Fly
aging GO:0007568 2 0.144
Worm
maintenance of location GO:0051235 4 0.131
organelle organization GO:0006996 227 0.104
Yeast Zebrafish Fly
lipid storage GO:0019915 1 0.101
regulation of biosynthetic process GO:0009889 250 0.100
establishment of localization GO:0051234 244 0.100
Rat
regulation of translational initiation GO:0006446 1 0.096
ion transport GO:0006811 114 0.095
embryonic organ development GO:0048568 381 0.087
protein metabolic process GO:0019538 183 0.086
Human Yeast Rat Worm
nuclear transport GO:0051169 4 0.086
Rat
microtubule organizing center organization GO:0031023 1 0.075
Fly
growth GO:0040007 174 0.073
cellular response to organic substance GO:0071310 105 0.072
Human Mouse Rat
regulation of gene expression GO:0010468 265 0.071
Human
neuron differentiation GO:0030182 353 0.070
single organism organelle organization GO:1902589 199 0.070
Yeast Zebrafish Fly
guanosine containing compound catabolic process GO:1901069 2 0.068
nucleic acid metabolic process GO:0090304 244 0.067
Yeast
guanosine containing compound metabolic process GO:1901068 4 0.067
response to topologically incorrect protein GO:0035966 2 0.067
regulation of primary metabolic process GO:0080090 311 0.066
Human Rat
regulation of developmental process GO:0050793 247 0.066
Fly
negative regulation of biological process GO:0048519 304 0.065
Human Rat Fly
positive regulation of transport GO:0051050 2 0.065
Rat
tube morphogenesis GO:0035239 349 0.059
embryonic organ morphogenesis GO:0048562 274 0.058
heart development GO:0007507 313 0.058
organic substance biosynthetic process GO:1901576 289 0.057
embryonic heart tube development GO:0035050 133 0.057
cellular component disassembly GO:0022411 1 0.056
generation of neurons GO:0048699 385 0.056
regionalization GO:0003002 274 0.055
Fly
cellular biosynthetic process GO:0044249 286 0.054
locomotion GO:0040011 313 0.054
Worm
cellular amine metabolic process GO:0044106 2 0.052
system process GO:0003008 185 0.052
determination of bilateral symmetry GO:0009855 204 0.051
response to wounding GO:0009611 116 0.051
cellular macromolecule metabolic process GO:0044260 391 0.050
Human Yeast Rat Worm
tissue homeostasis GO:0001894 25 0.049
establishment of protein localization to organelle GO:0072594 4 0.048
Rat
nucleocytoplasmic transport GO:0006913 4 0.048
Rat
cell death GO:0008219 121 0.048
Rat Worm
transport GO:0006810 220 0.047
Rat
positive regulation of cellular component biogenesis GO:0044089 3 0.047
regulation of cell shape GO:0008360 1 0.046
Fly
nitrogen compound metabolic process GO:0006807 319 0.045
Yeast Worm
macromolecular complex disassembly GO:0032984 1 0.045
heterocycle metabolic process GO:0046483 290 0.045
Yeast Worm
regulation of cellular metabolic process GO:0031323 320 0.045
Human Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
blood vessel morphogenesis GO:0048514 216 0.044
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.044
Yeast Worm
protein complex disassembly GO:0043241 1 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.042
cell motility GO:0048870 244 0.042
blood vessel development GO:0001568 246 0.041
cytokinesis GO:0000910 3 0.041
rna metabolic process GO:0016070 219 0.041
biosynthetic process GO:0009058 294 0.041
atp catabolic process GO:0006200 4 0.040
Yeast Worm
organelle assembly GO:0070925 110 0.039
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.039
positive regulation of biological process GO:0048518 253 0.039
Rat
protein import into nucleus GO:0006606 3 0.039
Rat
response to stress GO:0006950 263 0.039
Human Yeast Rat Worm Fly
positive regulation of cell cycle GO:0045787 3 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.038
regulation of response to stimulus GO:0048583 269 0.038
Human Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.038
Yeast Worm
amine metabolic process GO:0009308 2 0.037
axon development GO:0061564 166 0.037
heart looping GO:0001947 94 0.037
cognition GO:0050890 1 0.036
gtp metabolic process GO:0046039 4 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.036
multicellular organism growth GO:0035264 4 0.036
response to external stimulus GO:0009605 264 0.035
cell migration GO:0016477 237 0.035
anatomical structure homeostasis GO:0060249 36 0.035
Yeast
heart morphogenesis GO:0003007 156 0.035
signal transduction GO:0007165 455 0.035
Human
regulation of macromolecule metabolic process GO:0060255 317 0.034
Human Rat
regulation of cellular biosynthetic process GO:0031326 245 0.034
cell cycle process GO:0022402 53 0.034
Fly
positive regulation of exocytosis GO:0045921 1 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
vasculature development GO:0001944 278 0.033
single organism nuclear import GO:1902593 3 0.032
Rat
regulation of multicellular organismal process GO:0051239 277 0.032
Fly
pancreas development GO:0031016 84 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
positive regulation of gene expression GO:0010628 71 0.031
cellular response to chemical stimulus GO:0070887 157 0.031
Human Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
negative regulation of response to stimulus GO:0048585 104 0.031
cellular ketone metabolic process GO:0042180 11 0.031
neuron development GO:0048666 262 0.031
response to drug GO:0042493 3 0.031
response to hexose GO:0009746 3 0.031
oxoacid metabolic process GO:0043436 31 0.031
cellular response to stress GO:0033554 62 0.031
Yeast
cell projection organization GO:0030030 284 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
gtp catabolic process GO:0006184 2 0.030
determination of left right symmetry GO:0007368 179 0.030
multicellular organismal homeostasis GO:0048871 29 0.030
neurotransmitter transport GO:0006836 2 0.030
regulation of cell differentiation GO:0045595 142 0.030
determination of heart left right asymmetry GO:0061371 117 0.030
positive regulation of secretion by cell GO:1903532 1 0.029
positive regulation of cellular process GO:0048522 201 0.029
Rat
regulation of biological quality GO:0065008 263 0.029
Yeast Rat Fly
stem cell maintenance GO:0019827 4 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
Yeast Worm
cellular response to topologically incorrect protein GO:0035967 2 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
Worm
cytoskeleton organization GO:0007010 96 0.029
Zebrafish Fly
regulation of signal transduction GO:0009966 225 0.029
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.028
head development GO:0060322 303 0.028
macromolecular complex assembly GO:0065003 35 0.028
Yeast Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
Human
translation GO:0006412 5 0.028
cell substrate adhesion GO:0031589 4 0.028
single organism metabolic process GO:0044710 217 0.027
Yeast Worm
exocytosis GO:0006887 1 0.027
response to amino acid GO:0043200 2 0.027
negative regulation of cellular process GO:0048523 283 0.027
Human Rat Fly
regulation of binding GO:0051098 3 0.027
Rat
regulation of cell communication GO:0010646 232 0.027
Human
negative regulation of signal transduction GO:0009968 94 0.027
eye morphogenesis GO:0048592 144 0.027
regulation of cytoplasmic transport GO:1903649 4 0.026
Rat
regulation of multicellular organismal development GO:2000026 223 0.026
ribosome assembly GO:0042255 1 0.026
nucleoside monophosphate catabolic process GO:0009125 4 0.026
Yeast Worm
wound healing GO:0042060 90 0.026
neurotransmitter secretion GO:0007269 2 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
organic acid metabolic process GO:0006082 31 0.026
central nervous system development GO:0007417 387 0.026
rna localization GO:0006403 4 0.026
Fly
macromolecule biosynthetic process GO:0009059 227 0.025
positive regulation of secretion GO:0051047 1 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
Rat
centrosome duplication GO:0051298 1 0.025
fertilization GO:0009566 3 0.025
protein localization to plasma membrane GO:0072659 1 0.025
stem cell proliferation GO:0072089 4 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.025
Human Rat
nuclear import GO:0051170 3 0.025
Rat
ribonucleoprotein complex assembly GO:0022618 5 0.025
Yeast
protein localization to nucleus GO:0034504 3 0.025
Rat
negative regulation of protein phosphorylation GO:0001933 4 0.024
negative regulation of metabolic process GO:0009892 86 0.024
Human
sensory organ development GO:0007423 393 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
Human
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
response to uv GO:0009411 3 0.023
single fertilization GO:0007338 3 0.023
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
secondary metabolic process GO:0019748 3 0.023
regulation of cell activation GO:0050865 1 0.023
adult behavior GO:0030534 2 0.023
nucleic acid templated transcription GO:0097659 181 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
Yeast Worm
programmed cell death GO:0012501 119 0.023
Rat Worm
cellular component morphogenesis GO:0032989 336 0.022
Zebrafish Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
Yeast Worm
regulation of nucleoside metabolic process GO:0009118 2 0.022
apoptotic process GO:0006915 116 0.022
Rat Worm
localization of cell GO:0051674 244 0.022
regulation of protein targeting GO:1903533 2 0.022
Rat
eye development GO:0001654 277 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
Yeast Zebrafish Fly
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
regulation of mrna processing GO:0050684 3 0.022
response to unfolded protein GO:0006986 2 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
developmental growth GO:0048589 166 0.022
regulation of synapse assembly GO:0051963 3 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
angiogenesis GO:0001525 158 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
Rat
response to carbohydrate GO:0009743 3 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
Human
regulation of protein transport GO:0051223 3 0.021
Rat
rna processing GO:0006396 25 0.021
regulation of metal ion transport GO:0010959 4 0.021
negative regulation of cytokine production GO:0001818 1 0.020
ameboidal type cell migration GO:0001667 143 0.020
cellular protein metabolic process GO:0044267 129 0.020
Human Yeast Rat Worm
regulation of nucleotide catabolic process GO:0030811 2 0.020
mesenchyme development GO:0060485 127 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
Rat
response to chemical GO:0042221 320 0.020
Human Mouse Rat
response to monosaccharide GO:0034284 3 0.020
protein targeting to nucleus GO:0044744 3 0.020
Rat
cell death in response to oxidative stress GO:0036473 2 0.020
cellular component assembly GO:0022607 170 0.020
Yeast Zebrafish Fly
positive regulation of biosynthetic process GO:0009891 68 0.020
regulation of synapse organization GO:0050807 3 0.019
camera type eye development GO:0043010 222 0.019
ribonucleoprotein complex biogenesis GO:0022613 13 0.019
Yeast
positive regulation of cell activation GO:0050867 1 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
cytokinetic process GO:0032506 2 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
oocyte anterior posterior axis specification GO:0007314 4 0.019
Fly
regulation of cellular response to oxidative stress GO:1900407 2 0.019
specification of axis polarity GO:0065001 4 0.019
posttranscriptional gene silencing by rna GO:0035194 3 0.019
neuron projection morphogenesis GO:0048812 161 0.019
negative regulation of gene expression GO:0010629 65 0.018
Human
regulation of cytokine production GO:0001817 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
Yeast Worm
positive regulation of cellular catabolic process GO:0031331 3 0.018
cellular response to unfolded protein GO:0034620 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
cell projection morphogenesis GO:0048858 244 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Fly
single organism localization GO:1902578 225 0.018
Rat Fly
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
protein import GO:0017038 3 0.018
Rat
regulation of response to stress GO:0080134 36 0.018
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.018
regulation of translation GO:0006417 3 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
axis specification GO:0009798 43 0.017
Fly
response to radiation GO:0009314 51 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
negative regulation of rna splicing GO:0033119 1 0.017
retina development in camera type eye GO:0060041 146 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
neuron projection development GO:0031175 180 0.017
protein secretion GO:0009306 1 0.017
spermatid development GO:0007286 2 0.017
neurological system process GO:0050877 62 0.017
regulation of cellular component organization GO:0051128 86 0.017
Fly
transcription dna templated GO:0006351 181 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
positive regulation of cytokine production GO:0001819 2 0.017
negative regulation of kinase activity GO:0033673 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
Rat
cell matrix adhesion GO:0007160 4 0.017
small molecule metabolic process GO:0044281 77 0.016
Yeast Worm
cellular carbohydrate metabolic process GO:0044262 4 0.016
intracellular signal transduction GO:0035556 85 0.016
specification of symmetry GO:0009799 204 0.016
melanin metabolic process GO:0006582 2 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
Yeast Worm
microtubule based process GO:0007017 60 0.016
Fly
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
cellular component movement GO:0006928 335 0.016
response to glucose GO:0009749 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
nucleic acid transport GO:0050657 2 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
Zebrafish
cellular amino acid metabolic process GO:0006520 7 0.016
female gonad development GO:0008585 4 0.016
proximal distal pattern formation GO:0009954 1 0.016
single organism transport GO:0044765 206 0.016
Rat
muscle cell differentiation GO:0042692 139 0.016
Zebrafish
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
negative regulation of cell communication GO:0010648 96 0.016
protein complex subunit organization GO:0071822 46 0.016
Yeast Zebrafish Fly
regulation of stem cell proliferation GO:0072091 2 0.016
establishment of rna localization GO:0051236 3 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
transmembrane transport GO:0055085 120 0.015
metal ion transport GO:0030001 58 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
tissue regeneration GO:0042246 74 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of cell death GO:0010941 103 0.015
Rat
primary neural tube formation GO:0014020 1 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
regeneration GO:0031099 91 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
er nucleus signaling pathway GO:0006984 2 0.015
gastrulation GO:0007369 208 0.015
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
gene silencing by rna GO:0031047 4 0.015
response to abiotic stimulus GO:0009628 122 0.015
Yeast Rat Fly
meiotic chromosome segregation GO:0045132 3 0.015
cellular component biogenesis GO:0044085 178 0.015
Yeast Zebrafish Fly
nuclear export GO:0051168 1 0.015
muscle structure development GO:0061061 196 0.015
Zebrafish
positive regulation of neuron apoptotic process GO:0043525 1 0.015
negative regulation of translation GO:0017148 1 0.015
cellular response to external stimulus GO:0071496 2 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
cellular protein complex disassembly GO:0043624 1 0.015
mesenchymal cell proliferation GO:0010463 1 0.015
apical junction assembly GO:0043297 1 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
rna transport GO:0050658 2 0.015
meiotic nuclear division GO:0007126 4 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
spermatid differentiation GO:0048515 2 0.014
ribose phosphate metabolic process GO:0019693 27 0.014
Yeast Worm
cellular response to biotic stimulus GO:0071216 3 0.014
death GO:0016265 121 0.014
Rat Worm
rna splicing GO:0008380 16 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
Rat
regulation of signaling GO:0023051 235 0.014
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
cell part morphogenesis GO:0032990 246 0.014
response to hydrogen peroxide GO:0042542 3 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of transcription dna templated GO:0006355 213 0.014
cellular localization GO:0051641 97 0.014
Rat Fly
developmental process involved in reproduction GO:0003006 27 0.014
Mouse Worm Fly
chordate embryonic development GO:0043009 271 0.014
posttranscriptional regulation of gene expression GO:0010608 14 0.014
exocrine pancreas development GO:0031017 28 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
sensory organ morphogenesis GO:0090596 200 0.014
response to biotic stimulus GO:0009607 97 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
neural crest cell differentiation GO:0014033 72 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.013
somatic muscle development GO:0007525 4 0.013
striated muscle cell differentiation GO:0051146 129 0.013
Zebrafish
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
tissue remodeling GO:0048771 4 0.013
macromolecule modification GO:0043412 111 0.013
Rat Worm
regulation of calcium ion transport GO:0051924 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
negative regulation of signaling GO:0023057 96 0.013
mesenchymal cell differentiation GO:0048762 87 0.013
brain development GO:0007420 293 0.013
protein complex localization GO:0031503 1 0.013
immune system process GO:0002376 241 0.013
Human
regulation of dendrite development GO:0050773 3 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of localization GO:0032879 104 0.013
Rat
regulation of calcium ion dependent exocytosis GO:0017158 1 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of hormone secretion GO:0046883 2 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Yeast Rat Worm
regulation of gtpase activity GO:0043087 2 0.013
negative regulation of developmental process GO:0051093 65 0.013
regulation of rna metabolic process GO:0051252 224 0.013
somatic stem cell maintenance GO:0035019 1 0.013
defense response GO:0006952 47 0.013
Human Worm
regulation of muscle contraction GO:0006937 3 0.013
cell projection assembly GO:0030031 64 0.013
single organism biosynthetic process GO:0044711 71 0.013
cellular response to dna damage stimulus GO:0006974 24 0.012
ras protein signal transduction GO:0007265 7 0.012
single organism membrane fusion GO:0044801 2 0.012
regulation of organelle assembly GO:1902115 4 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
activation of mapk activity GO:0000187 3 0.012
protein homooligomerization GO:0051260 3 0.012
immune response GO:0006955 28 0.012
Human
positive regulation of reproductive process GO:2000243 2 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of exocytosis GO:0017157 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
negative regulation of reproductive process GO:2000242 3 0.012
cellular response to nutrient levels GO:0031669 2 0.012
nuclear migration GO:0007097 3 0.012
regulation of protein catabolic process GO:0042176 1 0.012
Human
interspecies interaction between organisms GO:0044419 4 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
skeletal muscle organ development GO:0060538 78 0.012
cell aging GO:0007569 2 0.012
hormone transport GO:0009914 2 0.012
regulation of protein metabolic process GO:0051246 56 0.012
Human Rat
actin filament based movement GO:0030048 1 0.012
cellular response to radiation GO:0071478 4 0.012
liver development GO:0001889 96 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.011
response to external biotic stimulus GO:0043207 97 0.011
positive regulation of neural precursor cell proliferation GO:2000179 1 0.011
mesenchymal cell development GO:0014031 78 0.011
muscle tissue development GO:0060537 110 0.011
pole plasm assembly GO:0007315 4 0.011
Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
Human
nucleobase containing compound transport GO:0015931 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
Fly
organic substance transport GO:0071702 58 0.011
Rat
peptidyl serine modification GO:0018209 2 0.011
chemotaxis GO:0006935 104 0.011
regulation of cell projection assembly GO:0060491 4 0.011
exocrine system development GO:0035272 28 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
response to light stimulus GO:0009416 46 0.011
protein acylation GO:0043543 3 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
centrosome organization GO:0051297 1 0.011
Fly
positive regulation of neuron death GO:1901216 1 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
posttranscriptional gene silencing GO:0016441 3 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
multicellular organismal signaling GO:0035637 22 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
macromolecule localization GO:0033036 54 0.011
Rat Fly
autophagy GO:0006914 4 0.011
fin regeneration GO:0031101 51 0.011
regulation of myotube differentiation GO:0010830 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
Rat
phosphorus metabolic process GO:0006793 109 0.011
Yeast Rat Worm
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
Yeast Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
ribosomal small subunit biogenesis GO:0042274 2 0.011
protein polymerization GO:0051258 4 0.011
meiotic cell cycle process GO:1903046 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of jak stat cascade GO:0046425 3 0.011
cellular response to dsrna GO:0071359 1 0.011
sensory system development GO:0048880 76 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.010
phagocytosis GO:0006909 3 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
positive regulation of embryonic development GO:0040019 3 0.010
regulation of reproductive process GO:2000241 4 0.010
heart contraction GO:0060047 71 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
establishment or maintenance of cell polarity GO:0007163 29 0.010
regulation of response to oxidative stress GO:1902882 2 0.010
spindle assembly GO:0051225 2 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
neural crest cell development GO:0014032 62 0.010
protein modification process GO:0036211 100 0.010
Rat Worm
mrna stabilization GO:0048255 4 0.010
cellular amide metabolic process GO:0043603 4 0.010
negative regulation of muscle cell differentiation GO:0051148 1 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
positive regulation of chromosome organization GO:2001252 1 0.010

hsp90ab1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.024
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
disease of metabolism DOID:0014667 0 0.018
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
myopathy DOID:423 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
cardiovascular system disease DOID:1287 0 0.013
muscle tissue disease DOID:66 0 0.013