Danio rerio

15 known processes

hspa8

heat shock protein 8

(Aliases: wu:fi48b06,wu:fb01g06,hsc70,MGC55272)

hspa8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.799
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.619
Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.418
locomotion GO:0040011 313 0.297
Worm Fly
maintenance of location GO:0051235 4 0.252
cellular protein catabolic process GO:0044257 4 0.214
microtubule based process GO:0007017 60 0.199
aging GO:0007568 2 0.195
Worm
transport GO:0006810 220 0.190
Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.184
organic substance biosynthetic process GO:1901576 289 0.168
Human
centrosome cycle GO:0007098 1 0.159
cell cycle GO:0007049 93 0.146
Worm
lipid storage GO:0019915 1 0.138
organic cyclic compound metabolic process GO:1901360 301 0.136
Human Worm
single organism biosynthetic process GO:0044711 71 0.134
rna metabolic process GO:0016070 219 0.132
Human
regulation of cell shape GO:0008360 1 0.130
nucleobase containing compound metabolic process GO:0006139 274 0.121
Human Worm
regulation of biological quality GO:0065008 263 0.121
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.119
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.117
ubiquitin dependent protein catabolic process GO:0006511 3 0.116
pole plasm assembly GO:0007315 4 0.109
proteasomal protein catabolic process GO:0010498 2 0.095
response to abiotic stimulus GO:0009628 122 0.095
Worm
biosynthetic process GO:0009058 294 0.093
Human
ribonucleoside monophosphate catabolic process GO:0009158 4 0.093
Human Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.088
heterocycle metabolic process GO:0046483 290 0.088
Human Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.084
meiotic cell cycle process GO:1903046 3 0.083
anterior posterior pattern specification GO:0009952 152 0.082
nitrogen compound metabolic process GO:0006807 319 0.082
Human Worm
protein polymerization GO:0051258 4 0.081
aromatic compound biosynthetic process GO:0019438 217 0.080
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.080
gene expression GO:0010467 252 0.080
Human Fly
regionalization GO:0003002 274 0.074
cellular macromolecule metabolic process GO:0044260 391 0.074
Human
regulation of primary metabolic process GO:0080090 311 0.073
Human
negative regulation of cellular process GO:0048523 283 0.072
Human Worm
transcription dna templated GO:0006351 181 0.070
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.070
Human Worm
guanosine containing compound metabolic process GO:1901068 4 0.070
response to light stimulus GO:0009416 46 0.070
apoptotic process GO:0006915 116 0.069
Worm
regulation of apoptotic process GO:0042981 98 0.067
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.067
Human Worm
meiotic chromosome segregation GO:0045132 3 0.066
cellular response to topologically incorrect protein GO:0035967 2 0.065
Fly
cell death GO:0008219 121 0.064
Worm
meiotic nuclear division GO:0007126 4 0.064
establishment of localization GO:0051234 244 0.064
Worm Fly
nuclear transport GO:0051169 4 0.062
regulation of metabolic process GO:0019222 359 0.062
Human Fly
organelle organization GO:0006996 227 0.062
organonitrogen compound metabolic process GO:1901564 74 0.061
Human Worm
multicellular organismal reproductive process GO:0048609 35 0.061
death GO:0016265 121 0.061
Worm
cytoskeleton organization GO:0007010 96 0.059
cytoskeleton dependent cytokinesis GO:0061640 3 0.059
fertilization GO:0009566 3 0.057
endoplasmic reticulum unfolded protein response GO:0030968 2 0.057
phosphate containing compound metabolic process GO:0006796 108 0.056
Human Worm
establishment of organelle localization GO:0051656 45 0.056
negative regulation of catabolic process GO:0009895 3 0.055
macromolecular complex subunit organization GO:0043933 74 0.055
gtp catabolic process GO:0006184 2 0.055
rna biosynthetic process GO:0032774 181 0.053
Human
organelle assembly GO:0070925 110 0.053
positive regulation of cellular catabolic process GO:0031331 3 0.053
reproductive process GO:0022414 40 0.053
response to topologically incorrect protein GO:0035966 2 0.052
Fly
single organism nuclear import GO:1902593 3 0.051
cellular transition metal ion homeostasis GO:0046916 3 0.051
protein import GO:0017038 3 0.049
establishment of localization in cell GO:0051649 77 0.049
Worm Fly
positive regulation of catabolic process GO:0009896 4 0.049
macromolecule localization GO:0033036 54 0.048
tube morphogenesis GO:0035239 349 0.048
atp catabolic process GO:0006200 4 0.048
Human Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
Human
oocyte anterior posterior axis specification GO:0007314 4 0.046
single organism organelle organization GO:1902589 199 0.046
cellular macromolecule biosynthetic process GO:0034645 224 0.045
Human
response to antibiotic GO:0046677 1 0.044
single organism localization GO:1902578 225 0.044
Worm Fly
angiogenesis GO:0001525 158 0.043
ncrna metabolic process GO:0034660 12 0.043
sexual reproduction GO:0019953 36 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.042
single organism metabolic process GO:0044710 217 0.042
Human Worm
cellular aromatic compound metabolic process GO:0006725 295 0.041
Human Worm
microtubule organizing center organization GO:0031023 1 0.041
single organism reproductive process GO:0044702 40 0.040
centrosome organization GO:0051297 1 0.040
vesicle mediated transport GO:0016192 22 0.040
Worm Fly
gtp metabolic process GO:0046039 4 0.040
positive regulation of cell cycle GO:0045787 3 0.039
Worm
regulation of metal ion transport GO:0010959 4 0.039
nucleocytoplasmic transport GO:0006913 4 0.038
peptidyl serine phosphorylation GO:0018105 1 0.038
centrosome duplication GO:0051298 1 0.037
regulation of protein binding GO:0043393 3 0.037
purine ribonucleotide metabolic process GO:0009150 27 0.037
Human Worm
cellular component biogenesis GO:0044085 178 0.037
spindle assembly GO:0051225 2 0.036
cytokinetic process GO:0032506 2 0.035
cellular response to unfolded protein GO:0034620 2 0.035
rna localization GO:0006403 4 0.035
growth GO:0040007 174 0.035
regulation of protein ubiquitination GO:0031396 3 0.034
response to chemical GO:0042221 320 0.034
Fly
er nucleus signaling pathway GO:0006984 2 0.034
regulation of locomotion GO:0040012 55 0.034
protein import into nucleus GO:0006606 3 0.034
protein localization to plasma membrane GO:0072659 1 0.034
negative regulation of nuclear division GO:0051784 3 0.034
small molecule metabolic process GO:0044281 77 0.034
Human Worm
response to radiation GO:0009314 51 0.033
cellular response to radiation GO:0071478 4 0.033
programmed cell death GO:0012501 119 0.033
Worm
carboxylic acid metabolic process GO:0019752 22 0.033
signal transduction GO:0007165 455 0.033
positive regulation of apoptotic signaling pathway GO:2001235 1 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
cellular response to external stimulus GO:0071496 2 0.032
regulation of cellular response to oxidative stress GO:1900407 2 0.031
endocardial cushion formation GO:0003272 2 0.031
cellular macromolecular complex assembly GO:0034622 24 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
Human
organelle localization GO:0051640 49 0.031
apoptotic process involved in morphogenesis GO:0060561 2 0.031
regulation of sequestering of calcium ion GO:0051282 4 0.030
cellular component disassembly GO:0022411 1 0.030
nucleic acid metabolic process GO:0090304 244 0.030
Human
regulation of signal transduction GO:0009966 225 0.030
mitochondrial transport GO:0006839 2 0.030
regulation of protein catabolic process GO:0042176 1 0.030
cytokinesis GO:0000910 3 0.030
regulation of cell communication GO:0010646 232 0.030
endocytosis GO:0006897 16 0.029
Worm
response to unfolded protein GO:0006986 2 0.029
cellular response to nutrient levels GO:0031669 2 0.029
response to inorganic substance GO:0010035 38 0.029
regulation of binding GO:0051098 3 0.029
cation transmembrane transport GO:0098655 65 0.029
negative regulation of cell death GO:0060548 60 0.028
germ cell development GO:0007281 22 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
macromolecule biosynthetic process GO:0009059 227 0.027
Human
single fertilization GO:0007338 3 0.027
positive regulation of protein complex assembly GO:0031334 2 0.027
regulation of wnt signaling pathway GO:0030111 53 0.027
embryonic organ development GO:0048568 381 0.027
cellular component assembly GO:0022607 170 0.027
purine nucleoside monophosphate catabolic process GO:0009128 4 0.027
Human Worm
regulation of receptor mediated endocytosis GO:0048259 4 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
Human
protein targeting to nucleus GO:0044744 3 0.026
wnt signaling pathway GO:0016055 80 0.026
positive regulation of transport GO:0051050 2 0.026
microtubule cytoskeleton organization GO:0000226 33 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
cell cycle process GO:0022402 53 0.026
Worm
apoptotic process involved in development GO:1902742 2 0.025
cellular amine metabolic process GO:0044106 2 0.025
organophosphate metabolic process GO:0019637 37 0.025
Human Worm
transmembrane transport GO:0055085 120 0.024
amine metabolic process GO:0009308 2 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
inorganic cation transmembrane transport GO:0098662 50 0.024
mitotic cell cycle process GO:1903047 48 0.024
cellular biosynthetic process GO:0044249 286 0.024
Human
regulation of cellular metabolic process GO:0031323 320 0.023
Human
actin filament based process GO:0030029 64 0.023
negative regulation of cellular catabolic process GO:0031330 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
intracellular transport GO:0046907 32 0.023
Worm
negative regulation of chromosome organization GO:2001251 1 0.023
cytoplasm organization GO:0007028 4 0.023
neuromast development GO:0048884 46 0.022
reproduction GO:0000003 40 0.022
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.022
Fly
negative regulation of programmed cell death GO:0043069 58 0.022
protein acetylation GO:0006473 2 0.022
dicarboxylic acid metabolic process GO:0043648 1 0.022
developmental growth GO:0048589 166 0.022
peptidyl serine modification GO:0018209 2 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
nuclear import GO:0051170 3 0.021
positive regulation of cellular process GO:0048522 201 0.021
Worm
multicellular organism growth GO:0035264 4 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of localization GO:0032879 104 0.021
protein localization to nucleus GO:0034504 3 0.021
macromolecule modification GO:0043412 111 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.021
homeostatic process GO:0042592 142 0.021
regulation of protein complex assembly GO:0043254 3 0.021
nucleic acid templated transcription GO:0097659 181 0.021
Human
negative regulation of biological process GO:0048519 304 0.021
Human Worm Fly
nucleoside monophosphate catabolic process GO:0009125 4 0.021
Human Worm
golgi vesicle transport GO:0048193 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
vesicle localization GO:0051648 27 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
protein stabilization GO:0050821 2 0.020
post embryonic development GO:0009791 7 0.020
Worm
response to uv GO:0009411 3 0.020
oocyte differentiation GO:0009994 14 0.020
adult behavior GO:0030534 2 0.019
maternal determination of anterior posterior axis embryo GO:0008358 4 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
Human Worm
regulation of biosynthetic process GO:0009889 250 0.019
Human
multicellular organism reproduction GO:0032504 35 0.019
protein metabolic process GO:0019538 183 0.019
Human
regulation of macromolecule metabolic process GO:0060255 317 0.019
Human Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
developmental process involved in reproduction GO:0003006 27 0.019
organic acid metabolic process GO:0006082 31 0.018
actin cytoskeleton organization GO:0030036 63 0.018
neuroblast proliferation GO:0007405 2 0.018
toxin transport GO:1901998 2 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of mrna processing GO:0050684 3 0.017
response to metal ion GO:0010038 34 0.017
chordate embryonic development GO:0043009 271 0.017
ion transport GO:0006811 114 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
receptor mediated endocytosis GO:0006898 6 0.017
Worm
single organism transport GO:0044765 206 0.017
Worm Fly
intracellular mrna localization GO:0008298 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
central nervous system development GO:0007417 387 0.017
nucleoside catabolic process GO:0009164 7 0.017
Human Worm
microtubule polymerization or depolymerization GO:0031109 3 0.017
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.017
mitochondrion organization GO:0007005 4 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
negative regulation of cell communication GO:0010648 96 0.016
positive regulation of translation GO:0045727 1 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
cell migration GO:0016477 237 0.016
cellular protein modification process GO:0006464 100 0.016
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.015
positive regulation of molecular function GO:0044093 33 0.015
glycosyl compound metabolic process GO:1901657 11 0.015
Human Worm
cartilage development GO:0051216 96 0.015
meiotic spindle organization GO:0000212 1 0.015
protein modification process GO:0036211 100 0.015
neuroblast fate commitment GO:0014017 1 0.015
mitotic cell cycle GO:0000278 64 0.015
Worm
detection of stimulus GO:0051606 29 0.015
response to organic substance GO:0010033 153 0.015
Fly
generation of neurons GO:0048699 385 0.015
Fly
heterocycle catabolic process GO:0046700 15 0.015
Human Worm
notochord development GO:0030903 54 0.015
macromolecular complex assembly GO:0065003 35 0.015
positive regulation of cytokine production GO:0001819 2 0.015
regulation of gene expression GO:0010468 265 0.015
Human Fly
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
epithelial cell morphogenesis GO:0003382 2 0.014
digestive system development GO:0055123 289 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
exocrine pancreas development GO:0031017 28 0.014
regulation of circadian rhythm GO:0042752 4 0.014
immune system development GO:0002520 191 0.014
exocytosis GO:0006887 1 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
Human
positive regulation of cytoskeleton organization GO:0051495 3 0.014
organelle fusion GO:0048284 3 0.014
regulation of cell death GO:0010941 103 0.014
gamete generation GO:0007276 33 0.014
regulation of cell morphogenesis GO:0022604 42 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
organonitrogen compound biosynthetic process GO:1901566 47 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
cellular respiration GO:0045333 3 0.014
synaptic vesicle transport GO:0048489 1 0.014
localization of cell GO:0051674 244 0.014
regulation of programmed cell death GO:0043067 101 0.014
rna modification GO:0009451 2 0.014
positive regulation of multi organism process GO:0043902 3 0.013
microtubule polymerization GO:0046785 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
head development GO:0060322 303 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
sensory organ development GO:0007423 393 0.013
cation transport GO:0006812 81 0.013
neuron development GO:0048666 262 0.013
Fly
neuron differentiation GO:0030182 353 0.013
Fly
response to stress GO:0006950 263 0.013
regulation of calcium ion transport GO:0051924 2 0.013
cell proliferation GO:0008283 80 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
regulation of transcription dna templated GO:0006355 213 0.013
Human
synaptic vesicle localization GO:0097479 1 0.013
oogenesis GO:0048477 14 0.013
regulation of cellular component movement GO:0051270 55 0.013
membrane organization GO:0061024 21 0.013
cellular protein metabolic process GO:0044267 129 0.013
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
intrinsic apoptotic signaling pathway GO:0097193 20 0.012
actin filament based movement GO:0030048 1 0.012
hemopoiesis GO:0030097 183 0.012
apical junction assembly GO:0043297 1 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
oxoacid metabolic process GO:0043436 31 0.012
cell motility GO:0048870 244 0.012
regulation of embryonic development GO:0045995 47 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
phototransduction GO:0007602 2 0.012
lipid localization GO:0010876 11 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
Human
metal ion transport GO:0030001 58 0.012
phagocytosis GO:0006909 3 0.012
regulation of signaling GO:0023051 235 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of signaling GO:0023057 96 0.011
actomyosin structure organization GO:0031032 53 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
interspecies interaction between organisms GO:0044419 4 0.011
blood coagulation GO:0007596 12 0.011
organism emergence from protective structure GO:0071684 4 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
cellular macromolecule catabolic process GO:0044265 12 0.011
respiratory electron transport chain GO:0022904 2 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
neural retina development GO:0003407 49 0.011
hormone secretion GO:0046879 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
actin filament polymerization GO:0030041 2 0.011
neuroblast differentiation GO:0014016 1 0.011
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.011
protein homooligomerization GO:0051260 3 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
Human
pronuclear migration GO:0035046 1 0.011
female gamete generation GO:0007292 14 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
interaction with host GO:0051701 4 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
gastrulation GO:0007369 208 0.011
multicellular organismal homeostasis GO:0048871 29 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
Human
g protein coupled receptor signaling pathway GO:0007186 74 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.011
establishment of spindle localization GO:0051293 12 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
endoplasmic reticulum organization GO:0007029 3 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
Human
digestive tract development GO:0048565 265 0.010
establishment of rna localization GO:0051236 3 0.010
regulation of cytokine production GO:0001817 3 0.010

hspa8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
nervous system disease DOID:863 0 0.015
neurodegenerative disease DOID:1289 0 0.015
disease of anatomical entity DOID:7 0 0.015
central nervous system disease DOID:331 0 0.015