Danio rerio

33 known processes

htra1a

HtrA serine peptidase 1a

(Aliases: htra1,zgc:92029)

htra1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.266
signal transduction GO:0007165 455 0.247
chordate embryonic development GO:0043009 271 0.221
regulation of multicellular organismal development GO:2000026 223 0.198
mediolateral intercalation GO:0060031 3 0.188
cell surface receptor signaling pathway GO:0007166 325 0.169
embryo development ending in birth or egg hatching GO:0009792 271 0.169
regulation of signal transduction GO:0009966 225 0.167
regionalization GO:0003002 274 0.164
segmentation GO:0035282 97 0.148
regulation of macromolecule metabolic process GO:0060255 317 0.147
Mouse Fly
regulation of gene expression GO:0010468 265 0.142
Mouse
macromolecule biosynthetic process GO:0009059 227 0.115
cognition GO:0050890 1 0.115
response to stress GO:0006950 263 0.112
Rat
cell morphogenesis GO:0000902 289 0.110
muscle structure development GO:0061061 196 0.109
phagocytosis GO:0006909 3 0.108
embryonic organ morphogenesis GO:0048562 274 0.107
somitogenesis GO:0001756 87 0.104
regulation of rna biosynthetic process GO:2001141 213 0.098
Mouse
somite development GO:0061053 96 0.097
cellular aromatic compound metabolic process GO:0006725 295 0.096
response to wounding GO:0009611 116 0.094
positive regulation of cellular component biogenesis GO:0044089 3 0.092
cellular macromolecule metabolic process GO:0044260 391 0.091
Fly
organelle organization GO:0006996 227 0.091
Fly
heterocycle biosynthetic process GO:0018130 215 0.089
negative regulation of signal transduction GO:0009968 94 0.089
Mouse
response to external stimulus GO:0009605 264 0.088
Rat
specification of symmetry GO:0009799 204 0.084
regulation of cellular biosynthetic process GO:0031326 245 0.082
Mouse
hematopoietic progenitor cell differentiation GO:0002244 23 0.080
regulation of multicellular organismal process GO:0051239 277 0.079
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.077
meiotic nuclear division GO:0007126 4 0.076
regulation of response to stimulus GO:0048583 269 0.075
digestive system development GO:0055123 289 0.075
regulation of nitrogen compound metabolic process GO:0051171 251 0.074
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.074
actin polymerization or depolymerization GO:0008154 2 0.072
nucleobase containing compound metabolic process GO:0006139 274 0.072
regulation of synapse assembly GO:0051963 3 0.071
mesenchyme development GO:0060485 127 0.071
regulation of establishment of protein localization GO:0070201 4 0.069
cellular biosynthetic process GO:0044249 286 0.069
regulation of developmental process GO:0050793 247 0.068
negative regulation of secretion GO:0051048 2 0.068
cell projection morphogenesis GO:0048858 244 0.068
positive regulation of cellular catabolic process GO:0031331 3 0.067
negative regulation of signaling GO:0023057 96 0.067
Mouse
localization of cell GO:0051674 244 0.067
chemotaxis GO:0006935 104 0.067
response to nutrient GO:0007584 3 0.065
larval development GO:0002164 2 0.064
single organism organelle organization GO:1902589 199 0.064
gene expression GO:0010467 252 0.064
generation of neurons GO:0048699 385 0.064
regulation of cytokine production GO:0001817 3 0.063
canonical wnt signaling pathway GO:0060070 48 0.063
enzyme linked receptor protein signaling pathway GO:0007167 106 0.063
locomotion GO:0040011 313 0.063
regulation of biosynthetic process GO:0009889 250 0.062
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.062
Mouse
morphogenesis of an epithelium GO:0002009 333 0.060
segment polarity determination GO:0007367 1 0.060
negative regulation of protein kinase activity GO:0006469 4 0.059
regulation of cellular metabolic process GO:0031323 320 0.058
Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.058
negative regulation of smoothened signaling pathway GO:0045879 6 0.058
regulation of rna metabolic process GO:0051252 224 0.058
Mouse
tube morphogenesis GO:0035239 349 0.058
cellular macromolecule biosynthetic process GO:0034645 224 0.058
regulation of nucleic acid templated transcription GO:1903506 213 0.057
Mouse
embryonic heart tube development GO:0035050 133 0.057
axonogenesis GO:0007409 152 0.056
maintenance of location GO:0051235 4 0.056
membrane invagination GO:0010324 1 0.055
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
cellular localization GO:0051641 97 0.055
determination of left right symmetry GO:0007368 179 0.054
protein secretion GO:0009306 1 0.053
nucleic acid metabolic process GO:0090304 244 0.053
cytokinesis GO:0000910 3 0.053
cell migration GO:0016477 237 0.052
positive regulation of biological process GO:0048518 253 0.052
Rat Fly
negative regulation of kinase activity GO:0033673 4 0.052
cytoskeleton dependent cytokinesis GO:0061640 3 0.052
phagocytosis engulfment GO:0006911 1 0.051
regulation of gtp catabolic process GO:0033124 2 0.050
protein metabolic process GO:0019538 183 0.050
Mouse Fly
transcription dna templated GO:0006351 181 0.050
establishment of protein localization to organelle GO:0072594 4 0.049
brain development GO:0007420 293 0.049
negative regulation of cellular process GO:0048523 283 0.049
Mouse
programmed cell death GO:0012501 119 0.049
Fly
wnt signaling pathway GO:0016055 80 0.049
modification dependent protein catabolic process GO:0019941 3 0.049
homeostatic process GO:0042592 142 0.049
skeletal system development GO:0001501 181 0.048
dorsal ventral pattern formation GO:0009953 125 0.048
negative regulation of cell communication GO:0010648 96 0.047
Mouse
protein modification process GO:0036211 100 0.047
transport GO:0006810 220 0.047
negative regulation of response to stimulus GO:0048585 104 0.047
Mouse Rat
spindle assembly GO:0051225 2 0.046
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.046
cytoskeleton organization GO:0007010 96 0.046
stem cell differentiation GO:0048863 117 0.045
peptide metabolic process GO:0006518 1 0.045
cell projection organization GO:0030030 284 0.045
positive regulation of cytokine production GO:0001819 2 0.044
protein targeting to nucleus GO:0044744 3 0.044
hematopoietic stem cell differentiation GO:0060218 20 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
positive regulation of map kinase activity GO:0043406 3 0.044
striated muscle tissue development GO:0014706 110 0.044
positive regulation of catabolic process GO:0009896 4 0.043
cellular ketone metabolic process GO:0042180 11 0.043
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.043
response to chemical GO:0042221 320 0.043
cellular amide metabolic process GO:0043603 4 0.043
positive regulation of transport GO:0051050 2 0.043
cilium morphogenesis GO:0060271 85 0.043
phosphorus metabolic process GO:0006793 109 0.043
single organism localization GO:1902578 225 0.043
regulation of cardiac muscle tissue development GO:0055024 1 0.042
hemopoiesis GO:0030097 183 0.042
single organism transport GO:0044765 206 0.042
regulation of programmed cell death GO:0043067 101 0.042
Fly
g1 s transition of mitotic cell cycle GO:0000082 1 0.042
system process GO:0003008 185 0.042
cellular response to external stimulus GO:0071496 2 0.041
cellular response to nutrient levels GO:0031669 2 0.041
cellular component biogenesis GO:0044085 178 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
organic substance biosynthetic process GO:1901576 289 0.040
cilium assembly GO:0042384 58 0.040
digestive tract morphogenesis GO:0048546 231 0.040
oxoacid metabolic process GO:0043436 31 0.040
regulation of cell communication GO:0010646 232 0.040
myeloid cell differentiation GO:0030099 86 0.040
regulation of protein complex assembly GO:0043254 3 0.039
positive regulation of cellular process GO:0048522 201 0.039
Rat Fly
cellular component movement GO:0006928 335 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.039
Mouse
digestive tract development GO:0048565 265 0.039
regulation of stem cell proliferation GO:0072091 2 0.038
cellular component morphogenesis GO:0032989 336 0.038
embryonic organ development GO:0048568 381 0.038
angiogenesis GO:0001525 158 0.038
negative regulation of map kinase activity GO:0043407 2 0.038
determination of heart left right asymmetry GO:0061371 117 0.037
divalent inorganic cation homeostasis GO:0072507 22 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.037
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.037
fin regeneration GO:0031101 51 0.037
determination of bilateral symmetry GO:0009855 204 0.037
aging GO:0007568 2 0.037
rna biosynthetic process GO:0032774 181 0.036
multicellular organism growth GO:0035264 4 0.036
regulation of protein transport GO:0051223 3 0.036
protein import GO:0017038 3 0.036
organic acid metabolic process GO:0006082 31 0.036
regulation of mrna splicing via spliceosome GO:0048024 3 0.036
regulation of heart growth GO:0060420 2 0.035
embryonic cranial skeleton morphogenesis GO:0048701 90 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.035
regeneration GO:0031099 91 0.035
vasculature development GO:0001944 278 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
heart morphogenesis GO:0003007 156 0.035
regulation of primary metabolic process GO:0080090 311 0.035
Mouse Fly
muscle cell differentiation GO:0042692 139 0.035
establishment of localization GO:0051234 244 0.035
behavior GO:0007610 74 0.034
cellular response to extracellular stimulus GO:0031668 2 0.034
chemosensory behavior GO:0007635 1 0.034
cell projection assembly GO:0030031 64 0.034
positive regulation of cytoskeleton organization GO:0051495 3 0.034
rna metabolic process GO:0016070 219 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.034
mitochondrion organization GO:0007005 4 0.034
Fly
sensory organ development GO:0007423 393 0.034
metal ion transport GO:0030001 58 0.034
mitotic cell cycle embryonic GO:0045448 2 0.033
calcium ion transport into cytosol GO:0060402 3 0.033
spinal cord development GO:0021510 46 0.033
taxis GO:0042330 109 0.033
phosphorylation GO:0016310 69 0.033
regulation of wnt signaling pathway GO:0030111 53 0.032
neuron differentiation GO:0030182 353 0.032
regulation of signaling GO:0023051 235 0.032
proteasomal protein catabolic process GO:0010498 2 0.032
embryonic heart tube morphogenesis GO:0003143 108 0.032
positive regulation of striated muscle tissue development GO:0045844 1 0.032
cell morphogenesis involved in differentiation GO:0000904 195 0.032
i kappab kinase nf kappab signaling GO:0007249 4 0.032
blood vessel development GO:0001568 246 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
positive regulation of muscle tissue development GO:1901863 1 0.031
positive regulation of signal transduction GO:0009967 56 0.031
developmental growth GO:0048589 166 0.031
regulation of dendrite morphogenesis GO:0048814 3 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
leukocyte differentiation GO:0002521 25 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.031
muscle tissue development GO:0060537 110 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
regulation of protein catabolic process GO:0042176 1 0.031
lateral line system development GO:0048925 76 0.031
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.031
regulation of nucleoside metabolic process GO:0009118 2 0.031
rna modification GO:0009451 2 0.031
cellular amine metabolic process GO:0044106 2 0.031
inositol lipid mediated signaling GO:0048017 2 0.031
cell fate commitment GO:0045165 99 0.031
regulation of transcription dna templated GO:0006355 213 0.030
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.030
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.030
mitotic cell cycle GO:0000278 64 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.030
positive regulation of muscle organ development GO:0048636 1 0.030
cell part morphogenesis GO:0032990 246 0.029
central nervous system development GO:0007417 387 0.029
amine metabolic process GO:0009308 2 0.029
wound healing GO:0042060 90 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
Mouse
anterior posterior pattern specification GO:0009952 152 0.029
regulation of biological quality GO:0065008 263 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.029
mitotic cell cycle process GO:1903047 48 0.029
positive regulation of multicellular organismal process GO:0051240 52 0.029
regulation of apoptotic process GO:0042981 98 0.028
Fly
response to other organism GO:0051707 97 0.028
Rat
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
protein acylation GO:0043543 3 0.028
neuron neuron synaptic transmission GO:0007270 1 0.028
macromolecule modification GO:0043412 111 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
muscle organ development GO:0007517 101 0.028
regulation of erk1 and erk2 cascade GO:0070372 4 0.028
convergent extension GO:0060026 118 0.028
regulation of autophagy GO:0010506 3 0.028
aromatic compound biosynthetic process GO:0019438 217 0.027
neuron projection morphogenesis GO:0048812 161 0.027
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
biosynthetic process GO:0009058 294 0.027
cell motility GO:0048870 244 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
cellular component assembly GO:0022607 170 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
negative regulation of secretion by cell GO:1903531 2 0.025
death GO:0016265 121 0.025
Fly
negative regulation of mitosis GO:0045839 3 0.025
nuclear transport GO:0051169 4 0.025
heart looping GO:0001947 94 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
cellular component disassembly GO:0022411 1 0.025
immune system development GO:0002520 191 0.025
chemical homeostasis GO:0048878 49 0.025
regulation of dendrite development GO:0050773 3 0.025
tissue regeneration GO:0042246 74 0.025
limbic system development GO:0021761 16 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
dorsal convergence GO:0060030 14 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of synapse organization GO:0050807 3 0.024
thrombocyte differentiation GO:0002574 4 0.024
embryonic neurocranium morphogenesis GO:0048702 15 0.024
rostrocaudal neural tube patterning GO:0021903 29 0.024
neuron projection development GO:0031175 180 0.024
protein import into nucleus GO:0006606 3 0.024
acylglycerol homeostasis GO:0055090 2 0.024
mesenchymal cell development GO:0014031 78 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
growth GO:0040007 174 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
Rat
convergent extension involved in axis elongation GO:0060028 26 0.024
response to corticosteroid GO:0031960 1 0.023
convergent extension involved in gastrulation GO:0060027 71 0.023
nuclear import GO:0051170 3 0.023
gastrulation GO:0007369 208 0.023
immune system process GO:0002376 241 0.023
Rat
regulation of intracellular protein transport GO:0033157 3 0.023
mechanoreceptor differentiation GO:0042490 37 0.023
spermatid differentiation GO:0048515 2 0.023
interspecies interaction between organisms GO:0044419 4 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
regulation of cellular response to growth factor stimulus GO:0090287 35 0.022
regulation of canonical wnt signaling pathway GO:0060828 34 0.022
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.022
gtp catabolic process GO:0006184 2 0.022
response to light stimulus GO:0009416 46 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
protein polymerization GO:0051258 4 0.022
regulation of mrna processing GO:0050684 3 0.022
regulation of cell substrate adhesion GO:0010810 1 0.022
negative regulation of dna metabolic process GO:0051053 4 0.022
regulation of system process GO:0044057 40 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
stem cell proliferation GO:0072089 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
axis elongation GO:0003401 31 0.022
sensory organ morphogenesis GO:0090596 200 0.022
regulation of binding GO:0051098 3 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
Fly
regulation of cellular amine metabolic process GO:0033238 0 0.022
female sex differentiation GO:0046660 4 0.022
autophagy GO:0006914 4 0.022
cellular component assembly involved in morphogenesis GO:0010927 107 0.022
single organism nuclear import GO:1902593 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
detection of mechanical stimulus involved in sensory perception of touch GO:0050976 2 0.021
intracellular signal transduction GO:0035556 85 0.021
positive regulation of jnk cascade GO:0046330 3 0.021
positive regulation of signaling GO:0023056 56 0.021
regulation of behavior GO:0050795 24 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of chemotaxis GO:0050920 18 0.021
actin cytoskeleton organization GO:0030036 63 0.021
organelle assembly GO:0070925 110 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
skeletal muscle organ development GO:0060538 78 0.021
ion transport GO:0006811 114 0.020
gtp metabolic process GO:0046039 4 0.020
meiosis i GO:0007127 1 0.020
negative regulation of cytokine production GO:0001818 1 0.020
nucleic acid templated transcription GO:0097659 181 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
detection of abiotic stimulus GO:0009582 24 0.020
cellular response to starvation GO:0009267 1 0.020
tissue remodeling GO:0048771 4 0.020
spinal cord anterior posterior patterning GO:0021512 1 0.020
neuron development GO:0048666 262 0.020
cell cycle GO:0007049 93 0.020
regulation of response to external stimulus GO:0032101 31 0.020
Rat
cell substrate adhesion GO:0031589 4 0.020
female meiotic division GO:0007143 2 0.020
regulation of cell projection assembly GO:0060491 4 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
Mouse
striated muscle cell differentiation GO:0051146 129 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
inositol phosphate metabolic process GO:0043647 1 0.019
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.019
protein localization to nucleus GO:0034504 3 0.019
erk1 and erk2 cascade GO:0070371 4 0.019
regulation of molecular function GO:0065009 70 0.019
Fly
carboxylic acid metabolic process GO:0019752 22 0.019
regulation of mitotic cell cycle GO:0007346 25 0.019
regulation of phosphorus metabolic process GO:0051174 43 0.019
production of molecular mediator of immune response GO:0002440 2 0.019
primitive hemopoiesis GO:0060215 27 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.019
blood vessel morphogenesis GO:0048514 216 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
pronephros development GO:0048793 69 0.019
heterocycle metabolic process GO:0046483 290 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
stem cell division GO:0017145 1 0.018
regulation of metabolic process GO:0019222 359 0.018
Mouse Fly
establishment of localization in cell GO:0051649 77 0.018
adult behavior GO:0030534 2 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
negative regulation of multicellular organismal process GO:0051241 69 0.018
meiotic cell cycle process GO:1903046 3 0.018
muscle cell development GO:0055001 115 0.018
regulation of protein polymerization GO:0032271 2 0.018
response to carbohydrate GO:0009743 3 0.018
regulation of protein metabolic process GO:0051246 56 0.018
Fly
regulation of gtpase activity GO:0043087 2 0.018
sequestering of metal ion GO:0051238 3 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
spindle assembly involved in mitosis GO:0090307 1 0.017
leukocyte proliferation GO:0070661 1 0.017
cytokinetic process GO:0032506 2 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
negative regulation of developmental process GO:0051093 65 0.017
embryonic limb morphogenesis GO:0030326 2 0.017
b cell differentiation GO:0030183 1 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
hepatic duct development GO:0061011 2 0.017
meiotic chromosome segregation GO:0045132 3 0.017
optic placode formation GO:0001743 4 0.017
ear development GO:0043583 127 0.017
dorsal ventral axis specification GO:0009950 14 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
inner ear development GO:0048839 126 0.017
fertilization GO:0009566 3 0.017
spindle assembly involved in meiosis GO:0090306 1 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
stem cell development GO:0048864 82 0.017
carbohydrate homeostasis GO:0033500 1 0.017
female gonad development GO:0008585 4 0.017
cellular protein catabolic process GO:0044257 4 0.016
negative regulation of nervous system development GO:0051961 22 0.016
optic placode formation involved in camera type eye formation GO:0046619 3 0.016
regulation of neurological system process GO:0031644 2 0.016
renal system process involved in regulation of blood volume GO:0001977 1 0.016
negative regulation of nuclear division GO:0051784 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
regulation of wound healing GO:0061041 2 0.016
detection of external stimulus GO:0009581 24 0.016
connective tissue development GO:0061448 99 0.016
apoptotic process GO:0006915 116 0.016
Fly
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
negative regulation of biological process GO:0048519 304 0.016
Mouse Rat
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.016
pancreas development GO:0031016 84 0.016
response to radiation GO:0009314 51 0.016
embryonic eye morphogenesis GO:0048048 30 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
single organism metabolic process GO:0044710 217 0.016
cellular protein modification process GO:0006464 100 0.016
somatic stem cell maintenance GO:0035019 1 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of nervous system development GO:0051960 90 0.015
atp catabolic process GO:0006200 4 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of cell cycle GO:0051726 52 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
positive regulation of cell cycle GO:0045787 3 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
skin development GO:0043588 54 0.015
positive regulation of secretion GO:0051047 1 0.015
positive regulation of striated muscle cell differentiation GO:0051155 1 0.015
periodic partitioning GO:0007365 1 0.015
response to uv GO:0009411 3 0.015
membrane fusion GO:0061025 2 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
sulfur compound metabolic process GO:0006790 13 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Mouse
gland development GO:0048732 143 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
multi organism process GO:0051704 134 0.015
Rat Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
leukocyte activation GO:0045321 12 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
protein stabilization GO:0050821 2 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.015
positive regulation of cell communication GO:0010647 56 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
hepatocyte proliferation GO:0072574 2 0.015
cell adhesion GO:0007155 40 0.015
eye development GO:0001654 277 0.015
positive regulation of biosynthetic process GO:0009891 68 0.015
regulation of neuron differentiation GO:0045664 56 0.015
negative chemotaxis GO:0050919 1 0.015
polyol metabolic process GO:0019751 1 0.015
developmental programmed cell death GO:0010623 4 0.014
Fly
recombinational repair GO:0000725 1 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
response to ketone GO:1901654 1 0.014
actomyosin structure organization GO:0031032 53 0.014
lipid storage GO:0019915 1 0.014
b cell activation GO:0042113 2 0.014
stem cell maintenance GO:0019827 4 0.014
protein complex disassembly GO:0043241 1 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
cellular cation homeostasis GO:0030003 17 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of cellular component organization GO:0051128 86 0.014
regulation of organ growth GO:0046620 3 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
proximal distal pattern formation GO:0009954 1 0.014
positive regulation of developmental process GO:0051094 50 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
Fly

htra1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.102
Human
myopathy DOID:423 0 0.024
cardiovascular system disease DOID:1287 0 0.024
cardiomyopathy DOID:0050700 0 0.024
muscular disease DOID:0080000 0 0.024
intrinsic cardiomyopathy DOID:0060036 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscle tissue disease DOID:66 0 0.024
heart disease DOID:114 0 0.024
nervous system disease DOID:863 0 0.019
Human
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.016