Danio rerio

112 known processes

htt

huntingtin

(Aliases: ZHD,hd)

htt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.161
embryonic organ development GO:0048568 381 0.159
response to alkaloid GO:0043279 2 0.085
immune system development GO:0002520 191 0.072
aging GO:0007568 2 0.065
Mouse
signal transduction GO:0007165 455 0.059
regionalization GO:0003002 274 0.057
Mouse
embryonic skeletal system development GO:0048706 97 0.053
digestive tract development GO:0048565 265 0.053
Mouse
meiotic nuclear division GO:0007126 4 0.051
embryonic organ morphogenesis GO:0048562 274 0.050
cellular response to extracellular stimulus GO:0031668 2 0.049
multicellular organism growth GO:0035264 4 0.048
organic substance biosynthetic process GO:1901576 289 0.046
Mouse
establishment of localization GO:0051234 244 0.044
Mouse
extracellular structure organization GO:0043062 27 0.043
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.042
regulation of multicellular organism growth GO:0040014 4 0.039
compound eye development GO:0048749 2 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
Mouse
meiotic chromosome segregation GO:0045132 3 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.036
embryonic skeletal system morphogenesis GO:0048704 93 0.035
maintenance of location GO:0051235 4 0.033
nitrogen compound metabolic process GO:0006807 319 0.032
Mouse
regulation of protein catabolic process GO:0042176 1 0.031
regulation of biological quality GO:0065008 263 0.031
extracellular matrix organization GO:0030198 27 0.031
peptidyl serine phosphorylation GO:0018105 1 0.030
rna transport GO:0050658 2 0.030
cellular response to starvation GO:0009267 1 0.030
meiotic cell cycle process GO:1903046 3 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Mouse
protein metabolic process GO:0019538 183 0.028
negative regulation of defense response GO:0031348 2 0.027
cortical cytoskeleton organization GO:0030865 1 0.027
phagocytosis GO:0006909 3 0.027
cell surface receptor signaling pathway GO:0007166 325 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
erk1 and erk2 cascade GO:0070371 4 0.026
mitochondrion organization GO:0007005 4 0.026
Mouse
rna localization GO:0006403 4 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
system process GO:0003008 185 0.026
Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.026
erythrocyte homeostasis GO:0034101 55 0.025
positive regulation of notch signaling pathway GO:0045747 3 0.025
regulation of binding GO:0051098 3 0.025
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.025
cellular protein catabolic process GO:0044257 4 0.025
cellular biosynthetic process GO:0044249 286 0.024
Mouse
small molecule metabolic process GO:0044281 77 0.024
Mouse
regulation of circadian rhythm GO:0042752 4 0.024
cellular response to external stimulus GO:0071496 2 0.024
regulation of synapse organization GO:0050807 3 0.023
cellular response to nutrient levels GO:0031669 2 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
dorsal ventral pattern formation GO:0009953 125 0.023
regulation of protein complex assembly GO:0043254 3 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
erythrocyte differentiation GO:0030218 54 0.023
nucleic acid transport GO:0050657 2 0.022
cartilage development GO:0051216 96 0.022
regulation of neurological system process GO:0031644 2 0.022
regulation of erk1 and erk2 cascade GO:0070372 4 0.022
spindle assembly GO:0051225 2 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
carbohydrate homeostasis GO:0033500 1 0.021
inner ear development GO:0048839 126 0.021
cell substrate adhesion GO:0031589 4 0.021
myeloid cell homeostasis GO:0002262 56 0.021
adult behavior GO:0030534 2 0.021
protein targeting to nucleus GO:0044744 3 0.021
Mouse
determination of bilateral symmetry GO:0009855 204 0.021
peptidyl serine modification GO:0018209 2 0.021
somatic muscle development GO:0007525 4 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.020
synaptic target recognition GO:0008039 1 0.020
lipid storage GO:0019915 1 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
response to uv GO:0009411 3 0.020
myeloid cell development GO:0061515 32 0.020
centrosome organization GO:0051297 1 0.020
protein import into nucleus GO:0006606 3 0.020
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
stem cell maintenance GO:0019827 4 0.020
gtp catabolic process GO:0006184 2 0.020
cellular modified amino acid metabolic process GO:0006575 3 0.020
Mouse
organic acid metabolic process GO:0006082 31 0.020
Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
erythrocyte development GO:0048821 24 0.020
protein localization to nucleus GO:0034504 3 0.019
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.019
cell morphogenesis GO:0000902 289 0.019
skeletal system development GO:0001501 181 0.019
negative regulation of cytoplasmic transport GO:1903650 2 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
regulation of molecular function GO:0065009 70 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
ribosomal small subunit biogenesis GO:0042274 2 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
cell matrix adhesion GO:0007160 4 0.018
biosynthetic process GO:0009058 294 0.018
Mouse
sensory organ development GO:0007423 393 0.018
cartilage morphogenesis GO:0060536 13 0.018
generation of neurons GO:0048699 385 0.018
regulation of cell communication GO:0010646 232 0.018
positive regulation of catabolic process GO:0009896 4 0.018
er to golgi vesicle mediated transport GO:0006888 1 0.018
Mouse
wnt signaling pathway GO:0016055 80 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
regulation of response to stimulus GO:0048583 269 0.017
sensory perception of mechanical stimulus GO:0050954 16 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
axon development GO:0061564 166 0.017
locomotion GO:0040011 313 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
establishment of rna localization GO:0051236 3 0.017
regulation of cell activation GO:0050865 1 0.017
ear development GO:0043583 127 0.017
nuclear transport GO:0051169 4 0.017
Mouse
protein acetylation GO:0006473 2 0.017
response to stress GO:0006950 263 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
immune system process GO:0002376 241 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
myeloid cell differentiation GO:0030099 86 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
protein modification process GO:0036211 100 0.016
regulation of protein binding GO:0043393 3 0.016
locomotor rhythm GO:0045475 3 0.016
response to chemical GO:0042221 320 0.016
Mouse
regulation of protein transport GO:0051223 3 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
neuron projection morphogenesis GO:0048812 161 0.016
gtp metabolic process GO:0046039 4 0.016
response to organic substance GO:0010033 153 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
ameboidal type cell migration GO:0001667 143 0.016
organism emergence from protective structure GO:0071684 4 0.016
cytokinesis GO:0000910 3 0.016
mesenchymal cell differentiation GO:0048762 87 0.016
digestive system development GO:0055123 289 0.016
Mouse
organelle organization GO:0006996 227 0.016
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
membrane invagination GO:0010324 1 0.015
microtubule organizing center organization GO:0031023 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
negative regulation of intracellular transport GO:0032387 3 0.015
actin filament based movement GO:0030048 1 0.015
cellular component biogenesis GO:0044085 178 0.015
protein polymerization GO:0051258 4 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
post embryonic organ development GO:0048569 4 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
cardiac atrium development GO:0003230 4 0.015
response to hydrogen peroxide GO:0042542 3 0.015
positive regulation of transport GO:0051050 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
protein dephosphorylation GO:0006470 3 0.015
phagocytosis engulfment GO:0006911 1 0.015
amine metabolic process GO:0009308 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
exocytosis GO:0006887 1 0.015
negative regulation of tor signaling GO:0032007 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.014
meiotic spindle organization GO:0000212 1 0.014
autophagy GO:0006914 4 0.014
hatching GO:0035188 4 0.014
positive regulation of cell division GO:0051781 2 0.014
chordate embryonic development GO:0043009 271 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
b cell activation GO:0042113 2 0.014
heart looping GO:0001947 94 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
cellular component disassembly GO:0022411 1 0.014
lateral line development GO:0048882 66 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
central nervous system development GO:0007417 387 0.014
single organism localization GO:1902578 225 0.014
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.014
defense response GO:0006952 47 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
gastrulation GO:0007369 208 0.014
Mouse
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of jak stat cascade GO:0046425 3 0.014
spermatid development GO:0007286 2 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
protein polyubiquitination GO:0000209 4 0.014
single organism metabolic process GO:0044710 217 0.014
Mouse
oxoacid metabolic process GO:0043436 31 0.013
Mouse
regulation of response to extracellular stimulus GO:0032104 1 0.013
lipid catabolic process GO:0016042 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of signal transduction GO:0009966 225 0.013
b cell differentiation GO:0030183 1 0.013
neuron differentiation GO:0030182 353 0.013
digestive tract morphogenesis GO:0048546 231 0.013
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
nucleic acid templated transcription GO:0097659 181 0.013
glucose homeostasis GO:0042593 1 0.013
glycoprotein metabolic process GO:0009100 23 0.013
circadian sleep wake cycle GO:0042745 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
Mouse
g2 dna damage checkpoint GO:0031572 3 0.013
response to carbohydrate GO:0009743 3 0.013
somitogenesis GO:0001756 87 0.013
cell projection morphogenesis GO:0048858 244 0.012
positive regulation of epithelial cell migration GO:0010634 2 0.012
heart morphogenesis GO:0003007 156 0.012
apoptotic process involved in development GO:1902742 2 0.012
cell growth GO:0016049 57 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
Mouse
neuron development GO:0048666 262 0.012
positive regulation of immune effector process GO:0002699 3 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
hormone secretion GO:0046879 2 0.012
Mouse
meiosis ii GO:0007135 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
pigment cell differentiation GO:0050931 38 0.012
negative chemotaxis GO:0050919 1 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
muscle structure development GO:0061061 196 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
negative regulation of immune response GO:0050777 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
neurotransmitter transport GO:0006836 2 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
hemopoiesis GO:0030097 183 0.012
forebrain development GO:0030900 96 0.012
Mouse
regulation of locomotion GO:0040012 55 0.012
positive regulation of cell activation GO:0050867 1 0.012
cell part morphogenesis GO:0032990 246 0.012
response to hexose GO:0009746 3 0.012
homeostasis of number of cells GO:0048872 62 0.012
erythrocyte maturation GO:0043249 8 0.011
taxis GO:0042330 109 0.011
response to nutrient GO:0007584 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
neural crest cell differentiation GO:0014033 72 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
vasculature development GO:0001944 278 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
pole plasm assembly GO:0007315 4 0.011
localization of cell GO:0051674 244 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
nucleobase containing compound transport GO:0015931 2 0.011
positive regulation of cell cycle GO:0045787 3 0.011
response to wounding GO:0009611 116 0.011
rna modification GO:0009451 2 0.011
rna metabolic process GO:0016070 219 0.011
brain development GO:0007420 293 0.011
Mouse
periodic partitioning GO:0007365 1 0.011
cellular protein metabolic process GO:0044267 129 0.011
protein acylation GO:0043543 3 0.011
regulation of transporter activity GO:0032409 2 0.011
centrosome cycle GO:0007098 1 0.011
response to biotic stimulus GO:0009607 97 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
sensory perception of smell GO:0007608 2 0.011
cardiac atrium morphogenesis GO:0003209 2 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
leukocyte differentiation GO:0002521 25 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
specification of symmetry GO:0009799 204 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
Mouse
activation of mapk activity GO:0000187 3 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
protein import GO:0017038 3 0.011
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
atp catabolic process GO:0006200 4 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
regulation of autophagy GO:0010506 3 0.010
determination of intestine left right asymmetry GO:0071908 2 0.010
primitive hemopoiesis GO:0060215 27 0.010
gene expression GO:0010467 252 0.010
cellular amide metabolic process GO:0043603 4 0.010
Mouse
response to external biotic stimulus GO:0043207 97 0.010
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.010
tissue remodeling GO:0048771 4 0.010
mesenchymal cell development GO:0014031 78 0.010
negative regulation of multi organism process GO:0043901 3 0.010
heterocycle metabolic process GO:0046483 290 0.010
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
cellular ketone metabolic process GO:0042180 11 0.010
chemotaxis GO:0006935 104 0.010

htt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013
eye and adnexa disease DOID:1492 0 0.013
organ system cancer DOID:0050686 0 0.012