Danio rerio

0 known processes

idh3b

isocitrate dehydrogenase 3 (NAD+) beta

(Aliases: zgc:86647)

idh3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
coenzyme biosynthetic process GO:0009108 2 0.297
dicarboxylic acid metabolic process GO:0043648 1 0.117
Rat
regulation of gene expression GO:0010468 265 0.089
cellular respiration GO:0045333 3 0.084
Rat
single organism metabolic process GO:0044710 217 0.078
Rat
oxidation reduction process GO:0055114 41 0.068
Rat
aging GO:0007568 2 0.056
cellular response to topologically incorrect protein GO:0035967 2 0.053
small molecule metabolic process GO:0044281 77 0.052
Rat
negative regulation of biological process GO:0048519 304 0.050
regulation of transcription dna templated GO:0006355 213 0.049
mitochondrion organization GO:0007005 4 0.048
multicellular organism growth GO:0035264 4 0.042
regulation of multicellular organism growth GO:0040014 4 0.039
rna biosynthetic process GO:0032774 181 0.039
er nucleus signaling pathway GO:0006984 2 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.037
Rat
nuclear transport GO:0051169 4 0.036
organic substance biosynthetic process GO:1901576 289 0.035
regulation of systemic arterial blood pressure GO:0003073 1 0.035
response to hydrogen peroxide GO:0042542 3 0.035
cellular response to chemical stimulus GO:0070887 157 0.033
maintenance of location GO:0051235 4 0.033
response to organic substance GO:0010033 153 0.032
quinone metabolic process GO:1901661 1 0.031
response to unfolded protein GO:0006986 2 0.031
heterocycle metabolic process GO:0046483 290 0.031
Rat
endoplasmic reticulum unfolded protein response GO:0030968 2 0.030
response to chemical GO:0042221 320 0.030
hydrogen peroxide metabolic process GO:0042743 2 0.029
system process GO:0003008 185 0.029
lipid storage GO:0019915 1 0.029
gene expression GO:0010467 252 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.028
regulation of metabolic process GO:0019222 359 0.028
rna metabolic process GO:0016070 219 0.028
cellular ketone metabolic process GO:0042180 11 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.026
regulation of cell activation GO:0050865 1 0.026
larval development GO:0002164 2 0.026
cellular protein catabolic process GO:0044257 4 0.026
protein import into nucleus GO:0006606 3 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
organic acid metabolic process GO:0006082 31 0.025
Rat
transcription dna templated GO:0006351 181 0.025
regulation of blood pressure GO:0008217 1 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
locomotion GO:0040011 313 0.025
amine metabolic process GO:0009308 2 0.024
adult behavior GO:0030534 2 0.024
behavior GO:0007610 74 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.024
Rat
cellular component assembly GO:0022607 170 0.024
protein localization to nucleus GO:0034504 3 0.023
protein localization to plasma membrane GO:0072659 1 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
zymogen activation GO:0031638 3 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.023
skeletal system development GO:0001501 181 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
cellular amino acid biosynthetic process GO:0008652 2 0.023
transmembrane transport GO:0055085 120 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
Rat
oxidoreduction coenzyme metabolic process GO:0006733 1 0.022
Rat
cellular amino acid metabolic process GO:0006520 7 0.022
regulation of reactive oxygen species metabolic process GO:2000377 2 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
regulation of cysteine type endopeptidase activity GO:2000116 21 0.022
small molecule catabolic process GO:0044282 3 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
regulation of rna biosynthetic process GO:2001141 213 0.021
response to stress GO:0006950 263 0.021
peptide metabolic process GO:0006518 1 0.021
regulation of rna metabolic process GO:0051252 224 0.021
nucleic acid templated transcription GO:0097659 181 0.021
cellular response to organic substance GO:0071310 105 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
immune system process GO:0002376 241 0.020
regulation of response to stimulus GO:0048583 269 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
negative regulation of kinase activity GO:0033673 4 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
oxoacid metabolic process GO:0043436 31 0.020
Rat
response to drug GO:0042493 3 0.020
alpha amino acid metabolic process GO:1901605 3 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
regulation of endopeptidase activity GO:0052548 23 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
intracellular estrogen receptor signaling pathway GO:0030520 3 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
positive regulation of transport GO:0051050 2 0.019
cellular response to reactive oxygen species GO:0034614 2 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
biosynthetic process GO:0009058 294 0.019
aromatic compound biosynthetic process GO:0019438 217 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
regulation of cell communication GO:0010646 232 0.018
camera type eye development GO:0043010 222 0.018
cellular amine metabolic process GO:0044106 2 0.018
kidney development GO:0001822 92 0.018
regulation of biosynthetic process GO:0009889 250 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
renal system development GO:0072001 94 0.018
meiotic cell cycle process GO:1903046 3 0.018
carboxylic acid catabolic process GO:0046395 3 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
sensory organ development GO:0007423 393 0.017
pyruvate metabolic process GO:0006090 1 0.017
sulfur compound biosynthetic process GO:0044272 9 0.017
mononuclear cell proliferation GO:0032943 1 0.017
response to wounding GO:0009611 116 0.017
regulation of programmed cell death GO:0043067 101 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
signal transduction GO:0007165 455 0.017
organelle organization GO:0006996 227 0.017
response to nutrient GO:0007584 3 0.017
mitochondrial transport GO:0006839 2 0.017
protein modification process GO:0036211 100 0.017
negative regulation of gene expression GO:0010629 65 0.017
protein stabilization GO:0050821 2 0.017
embryonic organ development GO:0048568 381 0.016
regulation of signal transduction GO:0009966 225 0.016
digestive system development GO:0055123 289 0.016
cell part morphogenesis GO:0032990 246 0.016
eye development GO:0001654 277 0.016
response to inorganic substance GO:0010035 38 0.016
phagocytosis GO:0006909 3 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
Rat
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of blood vessel size GO:0050880 2 0.015
cellular biosynthetic process GO:0044249 286 0.015
regulation of signaling GO:0023051 235 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
electron transport chain GO:0022900 2 0.015
multi organism process GO:0051704 134 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of cytokine production GO:0001817 3 0.014
regulation of tube size GO:0035150 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
single organism biosynthetic process GO:0044711 71 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
Rat
intracellular signal transduction GO:0035556 85 0.014
negative regulation of endopeptidase activity GO:0010951 10 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
negative regulation of protein processing GO:0010955 10 0.014
negative regulation of cellular process GO:0048523 283 0.014
regulation of peptidase activity GO:0052547 23 0.014
alcohol biosynthetic process GO:0046165 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
ion transport GO:0006811 114 0.014
cellular response to unfolded protein GO:0034620 2 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
cellular component movement GO:0006928 335 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
head development GO:0060322 303 0.014
protein homooligomerization GO:0051260 3 0.014
phosphorus metabolic process GO:0006793 109 0.013
Rat
gland development GO:0048732 143 0.013
regulation of protein catabolic process GO:0042176 1 0.013
atp catabolic process GO:0006200 4 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of primary metabolic process GO:0080090 311 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of protein transport GO:0051223 3 0.013
organic acid catabolic process GO:0016054 3 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
gtp metabolic process GO:0046039 4 0.013
positive regulation of cell activation GO:0050867 1 0.013
hepaticobiliary system development GO:0061008 98 0.013
regulation of biological quality GO:0065008 263 0.013
brain development GO:0007420 293 0.013
cellular amide metabolic process GO:0043603 4 0.013
superoxide metabolic process GO:0006801 2 0.013
liver development GO:0001889 96 0.012
negative regulation of metabolic process GO:0009892 86 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
positive regulation of metabolic process GO:0009893 108 0.012
developmental growth GO:0048589 166 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of wound healing GO:0061041 2 0.012
single organism localization GO:1902578 225 0.012
negative regulation of proteolysis GO:0045861 10 0.012
leukocyte proliferation GO:0070661 1 0.012
negative regulation of hydrolase activity GO:0051346 10 0.012
single organism nuclear import GO:1902593 3 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.012
protein targeting to nucleus GO:0044744 3 0.012
heart development GO:0007507 313 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
protein import GO:0017038 3 0.012
activation of mapk activity GO:0000187 3 0.012
lymphocyte proliferation GO:0046651 1 0.011
nucleotide metabolic process GO:0009117 28 0.011
Rat
phosphate containing compound metabolic process GO:0006796 108 0.011
Rat
phosphorylation GO:0016310 69 0.011
regulation of proteolysis GO:0030162 24 0.011
embryonic skeletal system development GO:0048706 97 0.011
single organism organelle organization GO:1902589 199 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
positive regulation of catabolic process GO:0009896 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
immune system development GO:0002520 191 0.011
lateral inhibition GO:0046331 1 0.011
cellular macromolecule metabolic process GO:0044260 391 0.011
meiotic nuclear division GO:0007126 4 0.011
nucleic acid metabolic process GO:0090304 244 0.011
response to uv GO:0009411 3 0.011
regulation of developmental process GO:0050793 247 0.011
proteolysis GO:0006508 38 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
response to other organism GO:0051707 97 0.011
sulfur compound metabolic process GO:0006790 13 0.011
nuclear import GO:0051170 3 0.011
nuclear export GO:0051168 1 0.011
regulation of protein maturation GO:1903317 10 0.011
regulation of apoptotic process GO:0042981 98 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cofactor biosynthetic process GO:0051188 10 0.011
cell death in response to oxidative stress GO:0036473 2 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
protein acetylation GO:0006473 2 0.010
b cell activation GO:0042113 2 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
response to biotic stimulus GO:0009607 97 0.010
cell death GO:0008219 121 0.010

idh3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.126
disease of metabolism DOID:0014667 0 0.126
mitochondrial metabolism disease DOID:700 0 0.126
disease of anatomical entity DOID:7 0 0.070
Human
disease of cellular proliferation DOID:14566 0 0.029
cancer DOID:162 0 0.029
nervous system disease DOID:863 0 0.028
Human
organ system cancer DOID:0050686 0 0.021
musculoskeletal system disease DOID:17 0 0.010