Danio rerio

129 known processes

igf1ra

insulin-like growth factor 1a receptor

(Aliases: IGF-IRa,wu:fi20b10)

igf1ra biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.900
response to stress GO:0006950 263 0.880
response to external stimulus GO:0009605 264 0.859
Rat Worm Fly
response to chemical GO:0042221 320 0.831
Rat Worm Fly
negative regulation of biological process GO:0048519 304 0.765
axon guidance GO:0007411 86 0.741
Fly
neuron development GO:0048666 262 0.730
Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.725
Human Mouse
larval development GO:0002164 2 0.653
Worm
locomotion GO:0040011 313 0.643
Human Zebrafish Worm Fly
neuron differentiation GO:0030182 353 0.623
female sex differentiation GO:0046660 4 0.622
Fly
female gonad development GO:0008585 4 0.615
Fly
embryonic organ development GO:0048568 381 0.614
negative regulation of endopeptidase activity GO:0010951 10 0.606
central nervous system development GO:0007417 387 0.601
neuron projection development GO:0031175 180 0.596
Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.557
negative regulation of cell communication GO:0010648 96 0.543
Human Mouse
single organism localization GO:1902578 225 0.537
Worm
cellular response to chemical stimulus GO:0070887 157 0.535
Fly
sensory organ morphogenesis GO:0090596 200 0.522
cellular macromolecule metabolic process GO:0044260 391 0.521
regulation of signaling GO:0023051 235 0.490
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.490
Human Mouse Rat
cellular response to organic substance GO:0071310 105 0.489
Fly
eye development GO:0001654 277 0.472
development of primary female sexual characteristics GO:0046545 4 0.469
Fly
cellular ketone metabolic process GO:0042180 11 0.464
organic substance biosynthetic process GO:1901576 289 0.442
Human Mouse Rat
signal transduction GO:0007165 455 0.441
cell surface receptor signaling pathway GO:0007166 325 0.431
regulation of cellular biosynthetic process GO:0031326 245 0.427
Human Mouse Rat
organic acid metabolic process GO:0006082 31 0.427
regulation of cell communication GO:0010646 232 0.421
Human Mouse Worm
immune system process GO:0002376 241 0.407
Human
regulation of multicellular organismal development GO:2000026 223 0.401
embryonic heart tube development GO:0035050 133 0.400
regulation of transcription dna templated GO:0006355 213 0.400
Mouse
cell part morphogenesis GO:0032990 246 0.400
Rat Fly
response to organic substance GO:0010033 153 0.396
Rat Fly
axon development GO:0061564 166 0.395
Rat Fly
taxis GO:0042330 109 0.394
Fly
regionalization GO:0003002 274 0.394
connective tissue development GO:0061448 99 0.392
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.385
response to decreased oxygen levels GO:0036293 25 0.371
Fly
nucleic acid metabolic process GO:0090304 244 0.370
Human Mouse Rat
defense response to bacterium GO:0042742 22 0.368
response to bacterium GO:0009617 58 0.368
homeostatic process GO:0042592 142 0.365
Fly
sensory organ development GO:0007423 393 0.359
response to organic cyclic compound GO:0014070 51 0.356
Rat Fly
vasculature development GO:0001944 278 0.356
nucleic acid templated transcription GO:0097659 181 0.353
Mouse
cell migration GO:0016477 237 0.353
Human Zebrafish
convergent extension GO:0060026 118 0.335
single organism transport GO:0044765 206 0.327
Worm
cellular component assembly GO:0022607 170 0.322
Human Rat Worm
positive regulation of biological process GO:0048518 253 0.321
Human Mouse Rat Worm Fly
eye morphogenesis GO:0048592 144 0.314
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.312
Rat Fly
cell morphogenesis GO:0000902 289 0.311
Rat Fly
gene expression GO:0010467 252 0.309
regulation of signal transduction GO:0009966 225 0.298
Human Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.297
chemotaxis GO:0006935 104 0.292
Fly
localization of cell GO:0051674 244 0.292
Human Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.290
Mouse
protein localization GO:0008104 40 0.286
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.276
regulation of anatomical structure size GO:0090066 33 0.274
Fly
negative regulation of signal transduction GO:0009968 94 0.270
Human Mouse
gastrulation with mouth forming second GO:0001702 44 0.268
regulation of peptidase activity GO:0052547 23 0.263
positive regulation of macromolecule metabolic process GO:0010604 93 0.263
Human Rat
gastrulation GO:0007369 208 0.258
regulation of rna metabolic process GO:0051252 224 0.256
Mouse
regulation of primary metabolic process GO:0080090 311 0.256
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.254
regulation of metabolic process GO:0019222 359 0.253
regulation of biological quality GO:0065008 263 0.246
Rat Worm Fly
cellular component movement GO:0006928 335 0.245
Human Zebrafish Fly
multi organism process GO:0051704 134 0.237
Zebrafish Worm Fly
negative regulation of response to stimulus GO:0048585 104 0.234
Human Mouse Fly
negative regulation of mitosis GO:0045839 3 0.232
organic cyclic compound metabolic process GO:1901360 301 0.229
Human Mouse Rat
extrinsic apoptotic signaling pathway GO:0097191 3 0.226
heterocycle metabolic process GO:0046483 290 0.221
Human Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.219
heart development GO:0007507 313 0.218
brain development GO:0007420 293 0.217
Mouse
response to oxygen containing compound GO:1901700 55 0.215
Rat Worm Fly
positive regulation of cellular process GO:0048522 201 0.213
Human Mouse Rat Fly
regulation of protein complex assembly GO:0043254 3 0.209
regulation of cell migration GO:0030334 40 0.205
Human
negative regulation of cellular component organization GO:0051129 16 0.203
cell migration involved in heart development GO:0060973 22 0.202
tube morphogenesis GO:0035239 349 0.199
negative regulation of cellular process GO:0048523 283 0.198
regulation of multicellular organismal process GO:0051239 277 0.197
Worm Fly
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.197
cell projection morphogenesis GO:0048858 244 0.197
Rat Fly
response to external biotic stimulus GO:0043207 97 0.195
hematopoietic or lymphoid organ development GO:0048534 191 0.194
regulation of locomotion GO:0040012 55 0.192
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.183
Human Mouse Rat
regulation of cell size GO:0008361 29 0.179
Fly
cellular response to endogenous stimulus GO:0071495 68 0.178
Fly
cellular component biogenesis GO:0044085 178 0.175
Human Rat Worm
regulation of macromolecule metabolic process GO:0060255 317 0.174
positive regulation of map kinase activity GO:0043406 3 0.173
Human
cellular localization GO:0051641 97 0.172
Worm
negative regulation of multicellular organismal process GO:0051241 69 0.172
Fly
programmed cell death GO:0012501 119 0.171
regulation of stem cell differentiation GO:2000736 4 0.170
response to biotic stimulus GO:0009607 97 0.170
regulation of establishment of protein localization GO:0070201 4 0.168
Worm
carboxylic acid metabolic process GO:0019752 22 0.167
regulation of carbohydrate metabolic process GO:0006109 4 0.166
rna metabolic process GO:0016070 219 0.163
Mouse
death GO:0016265 121 0.163
cellular aromatic compound metabolic process GO:0006725 295 0.163
Human Mouse Rat
response to endogenous stimulus GO:0009719 83 0.162
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.161
Mouse
regulation of response to stimulus GO:0048583 269 0.156
Human Mouse Worm Fly
response to wounding GO:0009611 116 0.156
convergent extension involved in organogenesis GO:0060029 10 0.154
protein localization to nucleus GO:0034504 3 0.154
Worm
response to oxygen levels GO:0070482 25 0.153
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.153
cellular macromolecule biosynthetic process GO:0034645 224 0.153
Human Mouse
heart morphogenesis GO:0003007 156 0.150
chemical homeostasis GO:0048878 49 0.150
cell migration to the midline involved in heart development GO:0003318 12 0.149
organic cyclic compound biosynthetic process GO:1901362 223 0.149
Mouse Rat
central nervous system neuron differentiation GO:0021953 74 0.149
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.145
heart looping GO:0001947 94 0.144
regulation of apoptotic process GO:0042981 98 0.143
cellular macromolecule localization GO:0070727 21 0.142
Worm
response to other organism GO:0051707 97 0.142
protein modification process GO:0036211 100 0.140
Human Mouse Fly
angiogenesis GO:0001525 158 0.138
regulation of programmed cell death GO:0043067 101 0.137
regulation of endopeptidase activity GO:0052548 23 0.135
cartilage development GO:0051216 96 0.134
amine metabolic process GO:0009308 2 0.129
pancreas development GO:0031016 84 0.127
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.124
embryonic heart tube morphogenesis GO:0003143 108 0.124
digestive tract development GO:0048565 265 0.123
negative regulation of signaling GO:0023057 96 0.122
Human Mouse
cellular amine metabolic process GO:0044106 2 0.122
regulation of cellular component movement GO:0051270 55 0.121
Human
axonogenesis GO:0007409 152 0.121
Rat Fly
oxoacid metabolic process GO:0043436 31 0.121
cellular carbohydrate metabolic process GO:0044262 4 0.118
single organismal cell cell adhesion GO:0016337 29 0.116
defense response to other organism GO:0098542 33 0.116
cell growth GO:0016049 57 0.113
Fly
regulation of cell projection assembly GO:0060491 4 0.111
cellular component morphogenesis GO:0032989 336 0.111
Rat Fly
positive regulation of transport GO:0051050 2 0.111
biosynthetic process GO:0009058 294 0.109
Human Mouse Rat
transport GO:0006810 220 0.108
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.108
regulation of cytokine production GO:0001817 3 0.108
cellular nitrogen compound metabolic process GO:0034641 290 0.107
Human Mouse Rat
single organism cellular localization GO:1902580 46 0.106
Worm
digestive tract morphogenesis GO:0048546 231 0.106
regulation of protein transport GO:0051223 3 0.105
Worm
regulation of tube size GO:0035150 2 0.105
camera type eye development GO:0043010 222 0.105
regulation of cysteine type endopeptidase activity GO:2000116 21 0.105
cilium assembly GO:0042384 58 0.104
negative regulation of protein kinase b signaling GO:0051898 2 0.104
Mouse
rna biosynthetic process GO:0032774 181 0.104
Mouse
cardioblast migration GO:0003260 7 0.103
negative regulation of developmental process GO:0051093 65 0.103
regulation of axon extension GO:0030516 24 0.102
regulation of cell motility GO:2000145 46 0.102
Human
long chain fatty acid transport GO:0015909 1 0.102
optic placode formation involved in camera type eye formation GO:0046619 3 0.102
phosphorylation GO:0016310 69 0.101
Human Mouse Fly
cell motility GO:0048870 244 0.101
Human Zebrafish
positive regulation of cell communication GO:0010647 56 0.100
Human Mouse
cell projection organization GO:0030030 284 0.100
Rat Fly
lipid biosynthetic process GO:0008610 22 0.100
Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.099
Mouse
establishment of localization GO:0051234 244 0.098
Worm
embryonic organ morphogenesis GO:0048562 274 0.098
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.098
heterocycle biosynthetic process GO:0018130 215 0.097
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.097
Human Mouse
aging GO:0007568 2 0.096
Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.096
Mouse
positive regulation of cytokine production GO:0001819 2 0.096
establishment of protein localization to organelle GO:0072594 4 0.094
Worm
regulation of neurogenesis GO:0050767 87 0.093
retina morphogenesis in camera type eye GO:0060042 79 0.093
regulation of response to external stimulus GO:0032101 31 0.092
Worm
negative regulation of peptidase activity GO:0010466 10 0.091
head development GO:0060322 303 0.091
Mouse
establishment of localization in cell GO:0051649 77 0.090
Worm
regulation of localization GO:0032879 104 0.088
Human Worm
developmental cell growth GO:0048588 52 0.087
Fly
formation of primary germ layer GO:0001704 62 0.087
cell migration involved in heart formation GO:0060974 10 0.087
cell death GO:0008219 121 0.085
single organism membrane fusion GO:0044801 2 0.085
protein import into nucleus GO:0006606 3 0.085
Worm
regulation of cellular component size GO:0032535 30 0.085
Fly
ovulation cycle GO:0042698 2 0.083
regulation of biosynthetic process GO:0009889 250 0.083
Human Mouse Rat
single organism nuclear import GO:1902593 3 0.082
Worm
maintenance of location GO:0051235 4 0.081
Worm
regulation of catalytic activity GO:0050790 55 0.081
digestive system development GO:0055123 289 0.081
Mouse
cell proliferation GO:0008283 80 0.080
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.080
Human Rat
regulation of inflammatory response GO:0050727 2 0.079
negative regulation of gene expression GO:0010629 65 0.078
regulation of gene expression GO:0010468 265 0.078
negative regulation of catalytic activity GO:0043086 21 0.078
motor neuron axon guidance GO:0008045 23 0.076
lipid storage GO:0019915 1 0.076
Worm
negative regulation of kinase activity GO:0033673 4 0.076
Human
intracellular signal transduction GO:0035556 85 0.075
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.074
Human Mouse Rat
cellular biosynthetic process GO:0044249 286 0.074
Human Mouse Rat
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.073
positive regulation of programmed cell death GO:0043068 29 0.073
neuron projection guidance GO:0097485 86 0.073
Fly
regulation of nervous system development GO:0051960 90 0.072
cation homeostasis GO:0055080 33 0.071
regulation of transferase activity GO:0051338 16 0.071
Human
regulation of cell death GO:0010941 103 0.071
lipid catabolic process GO:0016042 4 0.069
cation transport GO:0006812 81 0.069
positive regulation of stress activated mapk cascade GO:0032874 3 0.068
cellular response to growth factor stimulus GO:0071363 39 0.068
regulation of neuron differentiation GO:0045664 56 0.068
hemopoiesis GO:0030097 183 0.067
macromolecule modification GO:0043412 111 0.067
Human Mouse Fly
regulation of growth GO:0040008 42 0.067
Worm Fly
positive regulation of multicellular organismal process GO:0051240 52 0.066
Worm Fly
regulation of protein metabolic process GO:0051246 56 0.066
regulation of organelle organization GO:0033043 29 0.066
Mouse Worm
protein targeting to nucleus GO:0044744 3 0.066
Worm
skeletal system development GO:0001501 181 0.066
regulation of defense response GO:0031347 14 0.066
response to abiotic stimulus GO:0009628 122 0.065
Worm Fly
negative regulation of feeding behavior GO:2000252 2 0.064
Fly
positive regulation of epithelial cell differentiation GO:0030858 2 0.064
cellular response to hormone stimulus GO:0032870 39 0.064
Fly
regulation of developmental process GO:0050793 247 0.063
Zebrafish Worm Fly
regulation of molecular function GO:0065009 70 0.063
positive regulation of response to external stimulus GO:0032103 9 0.063
cell morphogenesis involved in differentiation GO:0000904 195 0.062
Rat Fly
myeloid cell differentiation GO:0030099 86 0.062
negative regulation of protein phosphorylation GO:0001933 4 0.062
Human
ion transport GO:0006811 114 0.061
positive regulation of response to wounding GO:1903036 5 0.061
regulation of organ growth GO:0046620 3 0.061
Fly
smooth muscle contraction GO:0006939 2 0.060
positive regulation of cellular biosynthetic process GO:0031328 68 0.059
Human Rat
oxidation reduction process GO:0055114 41 0.059
positive regulation of cellular protein metabolic process GO:0032270 22 0.059
Human
regulation of jak stat cascade GO:0046425 3 0.058
retina development in camera type eye GO:0060041 146 0.058
ion homeostasis GO:0050801 41 0.058
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.057
hepatic duct development GO:0061011 2 0.057
regulation of kinase activity GO:0043549 15 0.057
Human
neuron projection morphogenesis GO:0048812 161 0.057
Rat Fly
negative regulation of apoptotic process GO:0043066 55 0.057
lipid metabolic process GO:0006629 52 0.056
Rat Fly
stem cell differentiation GO:0048863 117 0.055
apoptotic signaling pathway GO:0097190 23 0.055
negative regulation of wnt signaling pathway GO:0030178 30 0.055
positive regulation of signal transduction GO:0009967 56 0.054
Human Mouse
camera type eye morphogenesis GO:0048593 108 0.054
immune response GO:0006955 28 0.053
Human
anterior head development GO:0097065 2 0.053
growth GO:0040007 174 0.053
metal ion homeostasis GO:0055065 26 0.052
response to monosaccharide GO:0034284 3 0.052
calcium ion transport into cytosol GO:0060402 3 0.052
negative regulation of nucleic acid templated transcription GO:1903507 45 0.052
regulation of cellular protein metabolic process GO:0032268 52 0.051
negative regulation of protein processing GO:0010955 10 0.051
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.051
nucleobase containing compound metabolic process GO:0006139 274 0.051
Human Mouse Rat
forebrain development GO:0030900 96 0.051
regulation of cell growth GO:0001558 29 0.050
Fly
regulation of developmental growth GO:0048638 38 0.050
Worm Fly
protein heterooligomerization GO:0051291 1 0.049
Rat
macromolecule localization GO:0033036 54 0.049
Worm
positive regulation of molecular function GO:0044093 33 0.049
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.049
Fly
epithelial tube morphogenesis GO:0060562 148 0.049
immune system development GO:0002520 191 0.049
cellular response to stress GO:0033554 62 0.049
Human Worm Fly
response to alkaloid GO:0043279 2 0.048
Fly
response to hormone GO:0009725 48 0.048
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.048
Human Mouse
ameboidal type cell migration GO:0001667 143 0.048
stem cell maintenance GO:0019827 4 0.048
morphogenesis of an epithelium GO:0002009 333 0.048
Mouse
defense response GO:0006952 47 0.048
spinal cord anterior posterior patterning GO:0021512 1 0.048
cilium organization GO:0044782 71 0.047
mediolateral intercalation GO:0060031 3 0.047
activation of mapk activity GO:0000187 3 0.047
Human
blood circulation GO:0008015 87 0.046
fatty acid metabolic process GO:0006631 5 0.046
nucleocytoplasmic transport GO:0006913 4 0.046
Worm
stem cell development GO:0048864 82 0.046
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.046
determination of bilateral symmetry GO:0009855 204 0.045
tissue regeneration GO:0042246 74 0.045
cellular protein localization GO:0034613 20 0.045
Worm
cellular response to external stimulus GO:0071496 2 0.045
Worm
appendage development GO:0048736 80 0.045
system process GO:0003008 185 0.044
rhythmic process GO:0048511 21 0.044
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.044
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.044
multicellular organism growth GO:0035264 4 0.044
Worm Fly
establishment of organelle localization GO:0051656 45 0.043
wnt signaling pathway GO:0016055 80 0.043
synaptic target recognition GO:0008039 1 0.043
neuron projection extension GO:1990138 45 0.043
positive regulation of carbohydrate metabolic process GO:0045913 1 0.043
positive regulation of response to stimulus GO:0048584 80 0.043
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.042
myeloid leukocyte differentiation GO:0002573 15 0.042
regulation of response to stress GO:0080134 36 0.042
Human Worm
cardiac cell fate commitment GO:0060911 1 0.042
neuroblast differentiation GO:0014016 1 0.041
segmentation GO:0035282 97 0.041
cellular lipid metabolic process GO:0044255 36 0.041
positive regulation of developmental process GO:0051094 50 0.041
Worm Fly
pigmentation GO:0043473 85 0.040
Zebrafish
response to nutrient GO:0007584 3 0.040
Rat
glucose homeostasis GO:0042593 1 0.040
response to corticosteroid GO:0031960 1 0.040
somitogenesis GO:0001756 87 0.039
notch signaling pathway GO:0007219 35 0.039
positive regulation of rna biosynthetic process GO:1902680 57 0.039
cognition GO:0050890 1 0.039
astrocyte differentiation GO:0048708 1 0.039
optic placode formation GO:0001743 4 0.039
response to growth factor GO:0070848 39 0.039
stem cell fate commitment GO:0048865 1 0.038
regulation of cytoplasmic transport GO:1903649 4 0.038
Worm
single organism cell adhesion GO:0098602 29 0.038
positive regulation of metabolic process GO:0009893 108 0.038
Human Mouse Rat
germ cell development GO:0007281 22 0.038
Fly
stem cell division GO:0017145 1 0.038
Fly
regulation of mrna processing GO:0050684 3 0.037
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.037
ectodermal placode development GO:0071696 37 0.037
positive regulation of protein metabolic process GO:0051247 23 0.037
Human
regulation of blood vessel size GO:0050880 2 0.037
chordate embryonic development GO:0043009 271 0.037
cellular amino acid metabolic process GO:0006520 7 0.036
erythrocyte homeostasis GO:0034101 55 0.036
regulation of hydrolase activity GO:0051336 28 0.036
lateral inhibition GO:0046331 1 0.036
negative regulation of protein kinase activity GO:0006469 4 0.035
Human
microtubule based process GO:0007017 60 0.035
developmental growth GO:0048589 166 0.035
negative regulation of cellular metabolic process GO:0031324 77 0.035
somatic stem cell maintenance GO:0035019 1 0.035
organelle organization GO:0006996 227 0.035
Mouse Worm
nuclear import GO:0051170 3 0.034
Worm
regulation of sequestering of calcium ion GO:0051282 4 0.034
negative regulation of axon guidance GO:1902668 1 0.034
transcription dna templated GO:0006351 181 0.033
Mouse
protein metabolic process GO:0019538 183 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.033
anion transport GO:0006820 38 0.033
response to carbohydrate GO:0009743 3 0.033
small molecule metabolic process GO:0044281 77 0.033
negative regulation of sequestering of calcium ion GO:0051283 4 0.033
determination of heart left right asymmetry GO:0061371 117 0.033
regulation of gastrulation GO:0010470 24 0.033
regulation of proteolysis GO:0030162 24 0.032
exocrine system development GO:0035272 28 0.032
Mouse
negative regulation of protein metabolic process GO:0051248 16 0.032
hormone mediated signaling pathway GO:0009755 9 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.032
Mouse
retinal ganglion cell axon guidance GO:0031290 35 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
protein secretion GO:0009306 1 0.032
smad protein complex assembly GO:0007183 1 0.032
regulation of axonogenesis GO:0050770 32 0.032
cellular protein metabolic process GO:0044267 129 0.031
regulation of phosphorylation GO:0042325 26 0.031
Human Mouse
negative regulation of molecular function GO:0044092 23 0.031
cellular macromolecular complex assembly GO:0034622 24 0.031
sensory system development GO:0048880 76 0.031
negative regulation of metabolic process GO:0009892 86 0.031
response to inorganic substance GO:0010035 38 0.031
positive regulation of gene expression GO:0010628 71 0.030
cell cycle arrest GO:0007050 1 0.030
embryonic skeletal system morphogenesis GO:0048704 93 0.030
sprouting angiogenesis GO:0002040 53 0.030
sequestering of calcium ion GO:0051208 3 0.030
regulation of phosphate metabolic process GO:0019220 43 0.030
Human Mouse
regulation of vasculature development GO:1901342 33 0.030
negative regulation of locomotion GO:0040013 18 0.030
forebrain cell migration GO:0021885 1 0.030
thrombocyte differentiation GO:0002574 4 0.029
regulation of jun kinase activity GO:0043506 3 0.029
regulation of circadian rhythm GO:0042752 4 0.029
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.029
regulation of carbohydrate biosynthetic process GO:0043255 1 0.029
autophagy GO:0006914 4 0.029
Worm Fly
forebrain regionalization GO:0021871 4 0.029
response to nitrogen compound GO:1901698 19 0.029
Fly
ovulation cycle process GO:0022602 2 0.029
negative regulation of rna metabolic process GO:0051253 48 0.029
cardiac atrium morphogenesis GO:0003209 2 0.029
regulation of cell differentiation GO:0045595 142 0.028
regulation of cellular component organization GO:0051128 86 0.028
Mouse Worm Fly
single organism biosynthetic process GO:0044711 71 0.028
Rat
regulation of angiogenesis GO:0045765 26 0.028
blood vessel development GO:0001568 246 0.028
negative regulation of cell migration GO:0030336 17 0.028
nuclear transport GO:0051169 4 0.028
Worm
digestive tract mesoderm development GO:0007502 1 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
dorsal convergence GO:0060030 14 0.027
positive regulation of catabolic process GO:0009896 4 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
erythrocyte differentiation GO:0030218 54 0.027
apoptotic process GO:0006915 116 0.027
response to glucocorticoid GO:0051384 1 0.027
embryonic cranial skeleton morphogenesis GO:0048701 90 0.027
anterior posterior axon guidance GO:0033564 5 0.027
cell adhesion GO:0007155 40 0.027
heart formation GO:0060914 13 0.027
organelle localization GO:0051640 49 0.026
insulin like growth factor receptor signaling pathway GO:0048009 4 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.026
embryonic hemopoiesis GO:0035162 53 0.026
protein complex subunit organization GO:0071822 46 0.026
Human Rat
regulation of behavior GO:0050795 24 0.026
Fly
negative regulation of protein localization to nucleus GO:1900181 2 0.026
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.026
Human
cardiac atrium development GO:0003230 4 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
Worm
protein import GO:0017038 3 0.026
Worm
negative regulation of chemotaxis GO:0050922 4 0.026
organic substance transport GO:0071702 58 0.025
Worm
regulation of multicellular organism growth GO:0040014 4 0.025
Worm Fly
macromolecular complex subunit organization GO:0043933 74 0.025
Human Rat
adult behavior GO:0030534 2 0.025
epithelial cell development GO:0002064 42 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
mesodermal cell migration GO:0008078 12 0.025
negative regulation of defense response GO:0031348 2 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.025
divalent inorganic cation homeostasis GO:0072507 22 0.025
cytokinesis GO:0000910 3 0.025
Rat
glial cell migration GO:0008347 3 0.025
positive regulation of protein complex assembly GO:0031334 2 0.025
negative regulation of striated muscle tissue development GO:0045843 2 0.025
dorsal ventral axis specification GO:0009950 14 0.024
developmental process involved in reproduction GO:0003006 27 0.024
Mouse Fly
cellular protein modification process GO:0006464 100 0.024
Human Mouse Fly
protein kinase b signaling GO:0043491 9 0.024
Mouse
wound healing GO:0042060 90 0.024
regulation of cellular response to stress GO:0080135 20 0.024
Human Worm
monocarboxylic acid metabolic process GO:0032787 17 0.024
regulation of cell development GO:0060284 100 0.024
protein phosphorylation GO:0006468 47 0.024
Human Mouse Fly
hematopoietic stem cell differentiation GO:0060218 20 0.024
homeostasis of number of cells GO:0048872 62 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
reproductive process GO:0022414 40 0.023
Zebrafish Mouse Worm Fly
sensory perception of chemical stimulus GO:0007606 3 0.023
spinal cord development GO:0021510 46 0.023
positive regulation of signaling GO:0023056 56 0.023
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.023
Human Mouse Rat
tube closure GO:0060606 1 0.023
regulation of cell morphogenesis GO:0022604 42 0.023
single organism organelle organization GO:1902589 199 0.023
Mouse
positive regulation of inflammatory response GO:0050729 1 0.023
response to radiation GO:0009314 51 0.023

igf1ra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
bone development disease DOID:0080006 0 0.026
bone disease DOID:0080001 0 0.026
musculoskeletal system disease DOID:17 0 0.026
connective tissue disease DOID:65 0 0.026