Danio rerio

143 known processes

igf1rb

insulin-like growth factor 1b receptor

(Aliases: fb03h06,IGF-IRb,IGF-IR,wu:fb03h06)

igf1rb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 274 0.969
Zebrafish
sensory organ development GO:0007423 393 0.943
gastrulation GO:0007369 208 0.934
regulation of metabolic process GO:0019222 359 0.932
defense response to bacterium GO:0042742 22 0.922
convergent extension GO:0060026 118 0.918
cellular component movement GO:0006928 335 0.899
protein import into nucleus GO:0006606 3 0.898
Worm
convergent extension involved in gastrulation GO:0060027 71 0.893
axon guidance GO:0007411 86 0.884
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.873
Rat Fly
protein targeting to nucleus GO:0044744 3 0.864
Worm
cell motility GO:0048870 244 0.862
regulation of cellular metabolic process GO:0031323 320 0.844
head development GO:0060322 303 0.842
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.840
Worm
cell morphogenesis GO:0000902 289 0.839
Rat Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.824
Rat Fly
cell part morphogenesis GO:0032990 246 0.811
Rat Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.800
Human Mouse
negative regulation of autophagy GO:0010507 1 0.799
Fly
protein localization to nucleus GO:0034504 3 0.791
Worm
central nervous system development GO:0007417 387 0.784
ear development GO:0043583 127 0.779
axonogenesis GO:0007409 152 0.774
Rat Fly
neuron development GO:0048666 262 0.764
Rat Fly
digestive tract morphogenesis GO:0048546 231 0.752
germ line stem cell division GO:0042078 1 0.746
Fly
regulation of gene expression GO:0010468 265 0.736
cell growth GO:0016049 57 0.732
Fly
regulation of signal transduction GO:0009966 225 0.714
Human Mouse
neuron projection development GO:0031175 180 0.708
Rat Fly
generation of neurons GO:0048699 385 0.706
circadian sleep wake cycle GO:0042745 2 0.692
Fly
single organism nuclear import GO:1902593 3 0.688
Worm
regulation of protein transport GO:0051223 3 0.677
Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.664
heart looping GO:0001947 94 0.651
regulation of nucleic acid templated transcription GO:1903506 213 0.649
Mouse
positive regulation of cell cycle GO:0045787 3 0.642
Mouse Rat
negative regulation of protein transport GO:0051224 3 0.642
Worm
regulation of transcription dna templated GO:0006355 213 0.642
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.638
nucleic acid metabolic process GO:0090304 244 0.635
Human Mouse Rat
regulation of cellular biosynthetic process GO:0031326 245 0.629
Human Mouse Rat
regulation of biosynthetic process GO:0009889 250 0.620
Human Mouse Rat
nucleic acid templated transcription GO:0097659 181 0.617
Mouse
heart development GO:0007507 313 0.613
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.613
Human Mouse Rat
muscle cell differentiation GO:0042692 139 0.603
Fly
cellular component morphogenesis GO:0032989 336 0.598
Rat Fly
single organism transport GO:0044765 206 0.598
Worm
morphogenesis of an epithelium GO:0002009 333 0.592
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.592
macroautophagy GO:0016236 1 0.588
Worm
response to decreased oxygen levels GO:0036293 25 0.586
Fly
tube morphogenesis GO:0035239 349 0.585
cell projection assembly GO:0030031 64 0.578
regulation of cell differentiation GO:0045595 142 0.575
autophagy GO:0006914 4 0.571
Worm Fly
organic substance biosynthetic process GO:1901576 289 0.569
Human Mouse Rat
neuron projection guidance GO:0097485 86 0.567
Fly
cell projection organization GO:0030030 284 0.562
Rat Fly
nucleocytoplasmic transport GO:0006913 4 0.560
Worm
regulation of establishment of protein localization GO:0070201 4 0.550
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.549
hemopoiesis GO:0030097 183 0.547
regulation of signaling GO:0023051 235 0.543
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.542
determination of bilateral symmetry GO:0009855 204 0.534
negative regulation of biological process GO:0048519 304 0.533
protein kinase b signaling GO:0043491 9 0.531
Mouse
stem cell division GO:0017145 1 0.529
Fly
regulation of protein targeting GO:1903533 2 0.527
Worm
localization of cell GO:0051674 244 0.519
cellular biosynthetic process GO:0044249 286 0.515
Human Mouse Rat
pigment cell differentiation GO:0050931 38 0.511
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.506
Rat Fly
digestive system development GO:0055123 289 0.499
Mouse
regulation of organ growth GO:0046620 3 0.499
Fly
heterocycle biosynthetic process GO:0018130 215 0.498
Mouse
regulation of autophagy GO:0010506 3 0.491
Worm Fly
lipid storage GO:0019915 1 0.485
Worm
response to chemical GO:0042221 320 0.481
Rat Worm Fly
brain development GO:0007420 293 0.476
Mouse
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.470
nitrogen compound metabolic process GO:0006807 319 0.469
Human Mouse Rat
positive regulation of stress activated mapk cascade GO:0032874 3 0.465
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.463
regulation of multicellular organismal development GO:2000026 223 0.463
regulation of protein kinase b signaling GO:0051896 8 0.460
Mouse
larval development GO:0002164 2 0.455
Worm
enzyme linked receptor protein signaling pathway GO:0007167 106 0.454
response to stress GO:0006950 263 0.452
cell migration involved in gastrulation GO:0042074 79 0.447
nucleobase containing compound biosynthetic process GO:0034654 205 0.439
Mouse
negative regulation of protein localization to nucleus GO:1900181 2 0.435
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.431
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.429
Mouse
regulation of developmental process GO:0050793 247 0.423
Zebrafish Worm Fly
forebrain development GO:0030900 96 0.422
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.421
Human Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.419
digestive tract development GO:0048565 265 0.419
ameboidal type cell migration GO:0001667 143 0.418
sleep GO:0030431 1 0.417
Fly
mesenchyme development GO:0060485 127 0.416
neuron differentiation GO:0030182 353 0.410
insulin like growth factor receptor signaling pathway GO:0048009 4 0.407
negative chemotaxis GO:0050919 1 0.403
developmental pigmentation GO:0048066 48 0.403
Zebrafish
protein import GO:0017038 3 0.402
Worm
establishment of localization in cell GO:0051649 77 0.401
Worm
regulation of biological quality GO:0065008 263 0.393
Rat Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.388
Human Mouse
inner ear development GO:0048839 126 0.388
stem cell development GO:0048864 82 0.387
sensory organ morphogenesis GO:0090596 200 0.386
development of primary female sexual characteristics GO:0046545 4 0.381
Fly
multi organism process GO:0051704 134 0.380
biosynthetic process GO:0009058 294 0.375
Human Mouse Rat
maintenance of location GO:0051235 4 0.373
Worm
negative regulation of response to stimulus GO:0048585 104 0.372
Human Mouse Fly
dorsal convergence GO:0060030 14 0.369
intracellular signal transduction GO:0035556 85 0.365
Human Mouse
gland development GO:0048732 143 0.364
Mouse
macromolecule biosynthetic process GO:0009059 227 0.359
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.358
Mouse Rat
rna biosynthetic process GO:0032774 181 0.352
Mouse
regulation of cell communication GO:0010646 232 0.351
Human Mouse Worm
cell projection morphogenesis GO:0048858 244 0.349
Rat Fly
heart morphogenesis GO:0003007 156 0.347
stem cell maintenance GO:0019827 4 0.346
cell migration GO:0016477 237 0.346
negative regulation of metabolic process GO:0009892 86 0.344
muscle structure development GO:0061061 196 0.337
Fly
female sex differentiation GO:0046660 4 0.335
Fly
nuclear transport GO:0051169 4 0.333
Worm
multicellular organism reproduction GO:0032504 35 0.333
signal transduction GO:0007165 455 0.330
negative regulation of catabolic process GO:0009895 3 0.330
Fly
negative regulation of signal transduction GO:0009968 94 0.329
Human Mouse
developmental cell growth GO:0048588 52 0.329
Fly
regulation of response to oxidative stress GO:1902882 2 0.326
Worm
embryonic heart tube development GO:0035050 133 0.325
growth GO:0040007 174 0.324
female gonad development GO:0008585 4 0.321
Fly
mesenchymal cell development GO:0014031 78 0.321
regulation of primary metabolic process GO:0080090 311 0.317
eye development GO:0001654 277 0.314
periodic partitioning GO:0007365 1 0.313
nucleobase containing compound metabolic process GO:0006139 274 0.311
Human Mouse Rat
neuron remodeling GO:0016322 1 0.310
Fly
embryonic organ morphogenesis GO:0048562 274 0.302
developmental growth GO:0048589 166 0.298
cellular macromolecule metabolic process GO:0044260 391 0.294
determination of left right symmetry GO:0007368 179 0.291
regulation of multicellular organismal process GO:0051239 277 0.287
Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.283
Human Mouse Rat
cellular response to starvation GO:0009267 1 0.283
Worm
cellular component assembly GO:0022607 170 0.280
Human Rat Worm
positive regulation of map kinase activity GO:0043406 3 0.279
Human
establishment of protein localization to organelle GO:0072594 4 0.279
Worm
dorsal ventral pattern formation GO:0009953 125 0.277
cellular aromatic compound metabolic process GO:0006725 295 0.277
Human Mouse Rat
tissue remodeling GO:0048771 4 0.276
pericardium development GO:0060039 1 0.274
response to oxygen levels GO:0070482 25 0.274
Fly
urogenital system development GO:0001655 97 0.274
Mouse
canonical wnt signaling pathway GO:0060070 48 0.272
regulation of response to stimulus GO:0048583 269 0.269
Human Mouse Worm Fly
regulation of intracellular protein transport GO:0033157 3 0.268
Worm
regulation of rna metabolic process GO:0051252 224 0.268
Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.265
gene expression GO:0010467 252 0.265
negative regulation of gene expression GO:0010629 65 0.264
response to oxidative stress GO:0006979 11 0.263
Worm Fly
response to wounding GO:0009611 116 0.260
chemotaxis GO:0006935 104 0.258
Fly
hindbrain development GO:0030902 91 0.255
regulation of response to nutrient levels GO:0032107 1 0.251
Worm
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.249
bmp signaling pathway GO:0030509 52 0.247
protein metabolic process GO:0019538 183 0.246
organic substance transport GO:0071702 58 0.246
Worm
regulation of synapse organization GO:0050807 3 0.242
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.241
myotube differentiation GO:0014902 45 0.239
Fly
wound healing GO:0042060 90 0.235
regulation of circadian rhythm GO:0042752 4 0.234
Fly
negative regulation of cellular process GO:0048523 283 0.233
somitogenesis GO:0001756 87 0.231
regulation of organ morphogenesis GO:2000027 35 0.229
synaptic target recognition GO:0008039 1 0.229
bmp signaling pathway involved in heart jogging GO:0003303 14 0.229
response to external stimulus GO:0009605 264 0.229
Rat Worm Fly
positive regulation of biological process GO:0048518 253 0.227
Human Mouse Rat Worm Fly
mesenchymal cell differentiation GO:0048762 87 0.226
regulation of neuron differentiation GO:0045664 56 0.225
regulation of cytoplasmic transport GO:1903649 4 0.224
Worm
hematopoietic or lymphoid organ development GO:0048534 191 0.223
regulation of rna biosynthetic process GO:2001141 213 0.220
Mouse
negative regulation of signaling GO:0023057 96 0.220
Human Mouse
segmentation GO:0035282 97 0.220
homeostatic process GO:0042592 142 0.218
Fly
mitotic cell cycle GO:0000278 64 0.218
Mouse
protein secretion GO:0009306 1 0.217
regulation of apoptotic process GO:0042981 98 0.215
sexual reproduction GO:0019953 36 0.214
stem cell differentiation GO:0048863 117 0.204
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.200
renal system development GO:0072001 94 0.198
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.194
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.193
cell cell signaling involved in cell fate commitment GO:0045168 12 0.192
g1 s transition of mitotic cell cycle GO:0000082 1 0.191
diencephalon development GO:0021536 58 0.191
response to other organism GO:0051707 97 0.190
anterior posterior pattern specification GO:0009952 152 0.189
Zebrafish
cell cycle g1 s phase transition GO:0044843 1 0.188
cognition GO:0050890 1 0.187
cellular localization GO:0051641 97 0.186
Worm
spinal cord development GO:0021510 46 0.186
response to bacterium GO:0009617 58 0.185
regulation of proteolysis GO:0030162 24 0.185
regulation of nervous system development GO:0051960 90 0.184
segment polarity determination GO:0007367 1 0.181
positive regulation of cell adhesion GO:0045785 1 0.180
positive regulation of cellular biosynthetic process GO:0031328 68 0.180
Human Rat
single organism organelle organization GO:1902589 199 0.179
Mouse
response to hexose GO:0009746 3 0.178
dorsal ventral axis specification GO:0009950 14 0.178
epithelial to mesenchymal transition GO:0001837 21 0.173
cell proliferation GO:0008283 80 0.172
Fly
negative regulation of feeding behavior GO:2000252 2 0.170
Fly
positive regulation of dna metabolic process GO:0051054 1 0.170
Human Rat
pronephros development GO:0048793 69 0.169
determination of heart left right asymmetry GO:0061371 117 0.169
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.169
blood vessel development GO:0001568 246 0.169
heart formation GO:0060914 13 0.168
cellular nitrogen compound metabolic process GO:0034641 290 0.167
Human Mouse Rat
transcription dna templated GO:0006351 181 0.164
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.164
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.164
striated muscle cell differentiation GO:0051146 129 0.164
Fly
cellular carbohydrate metabolic process GO:0044262 4 0.158
regulation of protein import into nucleus GO:0042306 2 0.157
Worm
ossification GO:0001503 23 0.154
camera type eye development GO:0043010 222 0.153
regulation of anatomical structure morphogenesis GO:0022603 130 0.152
negative regulation of protein phosphorylation GO:0001933 4 0.152
Human
regulation of response to stress GO:0080134 36 0.152
Human Worm
response to hypoxia GO:0001666 25 0.151
cardiac cell fate commitment GO:0060911 1 0.151
pigmentation GO:0043473 85 0.151
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.150
Human
regulation of cell adhesion GO:0030155 15 0.149
regulation of heart morphogenesis GO:2000826 17 0.149
nuclear import GO:0051170 3 0.148
Worm
multicellular organism growth GO:0035264 4 0.147
Worm Fly
positive regulation of lipid metabolic process GO:0045834 1 0.146
Rat
axonal defasciculation GO:0007414 2 0.144
locomotory behavior GO:0007626 34 0.143
Fly
cellular response to extracellular stimulus GO:0031668 2 0.142
Worm
negative regulation of growth GO:0045926 10 0.142
positive regulation of developmental process GO:0051094 50 0.142
Worm Fly
apoptotic process GO:0006915 116 0.142
cellular response to chemical stimulus GO:0070887 157 0.141
Fly
gamete generation GO:0007276 33 0.140
negative regulation of endopeptidase activity GO:0010951 10 0.139
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.139
specification of organ identity GO:0010092 2 0.138
regulation of cellular component movement GO:0051270 55 0.137
Human
cellular response to external stimulus GO:0071496 2 0.136
Worm
regulation of protein metabolic process GO:0051246 56 0.135
axon extension GO:0048675 45 0.135
regulation of cellular ketone metabolic process GO:0010565 7 0.135
regulation of heart growth GO:0060420 2 0.135
organic cyclic compound metabolic process GO:1901360 301 0.133
Human Mouse Rat
locomotion GO:0040011 313 0.133
regulation of neurogenesis GO:0050767 87 0.133
cellular response to organic substance GO:0071310 105 0.131
Fly
positive regulation of multicellular organismal process GO:0051240 52 0.130
Worm Fly
female gamete generation GO:0007292 14 0.129
Fly
axon development GO:0061564 166 0.129
Rat Fly
embryonic heart tube morphogenesis GO:0003143 108 0.129
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.128
germ cell development GO:0007281 22 0.128
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.128
Worm
regulation of embryonic development GO:0045995 47 0.127
negative regulation of cellular component organization GO:0051129 16 0.125
regulation of cardiac muscle tissue development GO:0055024 1 0.125
positive regulation of biosynthetic process GO:0009891 68 0.124
Human Rat
negative regulation of cellular metabolic process GO:0031324 77 0.122
response to nutrient GO:0007584 3 0.122
Rat
positive regulation of transport GO:0051050 2 0.121
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.121
negative regulation of sequestering of calcium ion GO:0051283 4 0.119
gastrulation with mouth forming second GO:0001702 44 0.119
cellular protein modification process GO:0006464 100 0.117
Human Mouse Fly
myeloid cell differentiation GO:0030099 86 0.117
transport GO:0006810 220 0.116
Worm
defense response GO:0006952 47 0.114
motor neuron axon guidance GO:0008045 23 0.114
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.114
wnt signaling pathway GO:0016055 80 0.113
regulation of protein catabolic process GO:0042176 1 0.113
positive regulation of macromolecule metabolic process GO:0010604 93 0.112
Human Rat
regulation of protein complex assembly GO:0043254 3 0.112
organic acid metabolic process GO:0006082 31 0.110
neuron projection extension GO:1990138 45 0.110
negative regulation of protein import into nucleus GO:0042308 2 0.110
Worm
negative regulation of cellular biosynthetic process GO:0031327 55 0.109
regulation of dna replication GO:0006275 3 0.109
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.108
Fly
negative regulation of rna metabolic process GO:0051253 48 0.108
positive regulation of cell division GO:0051781 2 0.107
Mouse Rat
negative regulation of axon guidance GO:1902668 1 0.107
defense response to gram negative bacterium GO:0050829 8 0.107
cilium assembly GO:0042384 58 0.106
reproductive process GO:0022414 40 0.105
smad protein complex assembly GO:0007183 1 0.105
negative regulation of developmental process GO:0051093 65 0.105
regulation of localization GO:0032879 104 0.104
Human Worm
vasculature development GO:0001944 278 0.104
negative regulation of protein kinase b signaling GO:0051898 2 0.104
Mouse
mesoderm development GO:0007498 88 0.104
regulation of cellular response to growth factor stimulus GO:0090287 35 0.103
aging GO:0007568 2 0.102
Worm Fly
establishment of localization GO:0051234 244 0.102
Worm
developmental process involved in reproduction GO:0003006 27 0.102
Mouse Fly
response to nitrogen compound GO:1901698 19 0.102
Fly
positive regulation of muscle cell differentiation GO:0051149 1 0.102
negative regulation of ras protein signal transduction GO:0046580 1 0.101
protein complex localization GO:0031503 1 0.101
regulation of stem cell differentiation GO:2000736 4 0.101
cell death GO:0008219 121 0.100
negative regulation of biosynthetic process GO:0009890 55 0.099
negative regulation of protein maturation GO:1903318 10 0.098
positive regulation of programmed cell death GO:0043068 29 0.097
reproduction GO:0000003 40 0.096
specification of symmetry GO:0009799 204 0.096
regulation of carbohydrate metabolic process GO:0006109 4 0.095
regulation of cell death GO:0010941 103 0.094
epithelial tube morphogenesis GO:0060562 148 0.094
protein modification process GO:0036211 100 0.093
Human Mouse Fly
regulation of cell motility GO:2000145 46 0.093
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.093
Human Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.092
determination of ventral identity GO:0048264 21 0.092
negative regulation of cytoplasmic transport GO:1903650 2 0.091
Worm
regulation of canonical wnt signaling pathway GO:0060828 34 0.091
transcription from rna polymerase ii promoter GO:0006366 80 0.090
multi organism reproductive process GO:0044703 36 0.090
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.090
exocrine system development GO:0035272 28 0.090
Mouse
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.089
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.089
regulation of anatomical structure size GO:0090066 33 0.089
Fly
cell cycle arrest GO:0007050 1 0.088
response to biotic stimulus GO:0009607 97 0.088
positive regulation of cellular process GO:0048522 201 0.088
Human Mouse Rat Fly
odontogenesis of dentin containing tooth GO:0042475 1 0.088
regulation of epithelial to mesenchymal transition GO:0010717 3 0.088
rna metabolic process GO:0016070 219 0.087
Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.086
sex determination GO:0007530 1 0.086
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.085
metencephalon development GO:0022037 27 0.085
establishment of organelle localization GO:0051656 45 0.085
striated muscle tissue development GO:0014706 110 0.085
regulation of intracellular signal transduction GO:1902531 57 0.085
Human Mouse
negative regulation of cell communication GO:0010648 96 0.084
Human Mouse
p38mapk cascade GO:0038066 1 0.084
eye morphogenesis GO:0048592 144 0.084
regulation of cell growth GO:0001558 29 0.084
Fly
anatomical structure homeostasis GO:0060249 36 0.084
Fly
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.082
regulation of protein modification process GO:0031399 29 0.082
Human
response to heat GO:0009408 6 0.082
Worm
response to temperature stimulus GO:0009266 15 0.082
Worm
fin regeneration GO:0031101 51 0.082
positive regulation of rna metabolic process GO:0051254 59 0.081
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.080
forebrain cell migration GO:0021885 1 0.080
positive regulation of metabolic process GO:0009893 108 0.080
Human Mouse Rat
pronephric duct development GO:0039022 13 0.080
gland morphogenesis GO:0022612 13 0.079
Mouse
cellular lipid metabolic process GO:0044255 36 0.078
negative regulation of protein kinase activity GO:0006469 4 0.078
Human
photoreceptor cell fate commitment GO:0046552 1 0.078
reactive oxygen species metabolic process GO:0072593 6 0.078
Fly
death GO:0016265 121 0.077
cell fate specification GO:0001708 68 0.076
lateral inhibition GO:0046331 1 0.076
blood vessel morphogenesis GO:0048514 216 0.074
regulation of muscle organ development GO:0048634 9 0.074
regulation of tube size GO:0035150 2 0.073
endodermal cell fate commitment GO:0001711 18 0.073
cellular ketone metabolic process GO:0042180 11 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.072
Human Rat
immune system development GO:0002520 191 0.072
negative regulation of nucleic acid templated transcription GO:1903507 45 0.072
response to extracellular stimulus GO:0009991 10 0.071
Rat Worm
negative regulation of cell differentiation GO:0045596 46 0.070
skeletal muscle organ development GO:0060538 78 0.070
oxoacid metabolic process GO:0043436 31 0.069
ventral spinal cord development GO:0021517 35 0.069
regulation of cellular protein metabolic process GO:0032268 52 0.067
lipid metabolic process GO:0006629 52 0.067
Rat Fly
positive regulation of cell proliferation GO:0008284 15 0.067
Fly
regulation of cellular amine metabolic process GO:0033238 0 0.067
organ formation GO:0048645 17 0.067
epithelial cell differentiation GO:0030855 116 0.067
cilium morphogenesis GO:0060271 85 0.065
positive regulation of transcription dna templated GO:0045893 57 0.065
establishment of mitotic spindle orientation GO:0000132 10 0.065
cell fate commitment GO:0045165 99 0.064
positive regulation of apoptotic process GO:0043065 29 0.064
protein complex subunit organization GO:0071822 46 0.064
Human Rat
heterocycle metabolic process GO:0046483 290 0.063
Human Mouse Rat
regulation of multicellular organism growth GO:0040014 4 0.063
Worm Fly
signal transduction in absence of ligand GO:0038034 1 0.063
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.063
regulation of cytokine production GO:0001817 3 0.062
positive regulation of jnk cascade GO:0046330 3 0.062
regulation of cell development GO:0060284 100 0.061
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.061
positive regulation of response to stimulus GO:0048584 80 0.061
Human Mouse
negative regulation of striated muscle tissue development GO:0045843 2 0.061
negative regulation of neurogenesis GO:0050768 20 0.061
axoneme assembly GO:0035082 9 0.061
retina development in camera type eye GO:0060041 146 0.061
striated muscle cell development GO:0055002 108 0.060
single organism localization GO:1902578 225 0.059
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.059
tissue regeneration GO:0042246 74 0.059
cardioblast migration GO:0003260 7 0.059
peptidyl tyrosine phosphorylation GO:0018108 5 0.058
Human Mouse Fly
inner ear receptor cell differentiation GO:0060113 29 0.058
positive regulation of rna biosynthetic process GO:1902680 57 0.058
interaction with host GO:0051701 4 0.058
myeloid leukocyte differentiation GO:0002573 15 0.058
positive regulation of signaling GO:0023056 56 0.058
Human Mouse
regulation of catalytic activity GO:0050790 55 0.058
response to drug GO:0042493 3 0.058
reactive oxygen species biosynthetic process GO:1903409 1 0.057
regulation of cysteine type endopeptidase activity GO:2000116 21 0.057
regulation of lipase activity GO:0060191 2 0.057
regulation of response to extracellular stimulus GO:0032104 1 0.057
Worm
positive regulation of muscle tissue development GO:1901863 1 0.056
kidney development GO:0001822 92 0.056
zymogen activation GO:0031638 3 0.056
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.056
macromolecule localization GO:0033036 54 0.056
Worm
outflow tract morphogenesis GO:0003151 1 0.056
organ growth GO:0035265 12 0.056
Fly
regulation of cell cycle process GO:0010564 20 0.056
Mouse Rat
cell substrate adhesion GO:0031589 4 0.056
organelle assembly GO:0070925 110 0.055
Worm
endocrine system development GO:0035270 65 0.055
heart field specification GO:0003128 1 0.055
positive regulation of epithelial cell proliferation GO:0050679 1 0.055
muscle organ development GO:0007517 101 0.055
nuclear division GO:0000280 23 0.054
Mouse
oogenesis GO:0048477 14 0.054
Fly
organelle localization GO:0051640 49 0.054
negative regulation of cell proliferation GO:0008285 8 0.054
camera type eye morphogenesis GO:0048593 108 0.053
heart contraction GO:0060047 71 0.053
response to abiotic stimulus GO:0009628 122 0.053
Worm Fly
single organism metabolic process GO:0044710 217 0.053
Human Mouse Rat Worm Fly
developmental induction GO:0031128 10 0.052
regulation of inflammatory response GO:0050727 2 0.052
single organism cellular localization GO:1902580 46 0.051
Worm
response to corticosteroid GO:0031960 1 0.051
meiotic nuclear division GO:0007126 4 0.051
developmental growth involved in morphogenesis GO:0060560 86 0.051
behavior GO:0007610 74 0.051
Fly
cell type specific apoptotic process GO:0097285 22 0.051
Rat
regulation of phosphate metabolic process GO:0019220 43 0.051
Human Mouse
regulation of cell fate specification GO:0042659 20 0.051
response to oxygen containing compound GO:1901700 55 0.051
Rat Worm Fly
regulation of cell substrate adhesion GO:0010810 1 0.050
negative regulation of neuron projection development GO:0010977 9 0.050
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.050
cellular response to biotic stimulus GO:0071216 3 0.050
olfactory lobe development GO:0021988 4 0.049
cellular response to hypoxia GO:0071456 1 0.049
mapk cascade GO:0000165 18 0.049
Human Mouse
exocrine pancreas development GO:0031017 28 0.049
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.048
cellular protein localization GO:0034613 20 0.048
Worm
regulation of phosphorylation GO:0042325 26 0.048
Human Mouse
positive regulation of protein kinase b signaling GO:0051897 1 0.048
Mouse
regulation of developmental pigmentation GO:0048070 6 0.048
Zebrafish
extracellular matrix assembly GO:0085029 1 0.048

igf1rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.196