Danio rerio

17 known processes

igfbp1a

insulin-like growth factor binding protein 1a

(Aliases: igfbp1,cb656,IGFBP-1)

igfbp1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to stress GO:0006950 263 0.752
response to transition metal nanoparticle GO:1990267 28 0.698
response to drug GO:0042493 3 0.478
response to monosaccharide GO:0034284 3 0.475
response to chemical GO:0042221 320 0.375
response to organic substance GO:0010033 153 0.350
organic cyclic compound metabolic process GO:1901360 301 0.341
Zebrafish
response to antibiotic GO:0046677 1 0.303
cognition GO:0050890 1 0.292
positive regulation of cell cycle GO:0045787 3 0.282
blood vessel morphogenesis GO:0048514 216 0.272
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.265
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.261
Zebrafish
negative regulation of cellular process GO:0048523 283 0.254
regulation of multicellular organismal process GO:0051239 277 0.249
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.247
signal transduction GO:0007165 455 0.225
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.223
Zebrafish
heterocycle metabolic process GO:0046483 290 0.222
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.221
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.211
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.191
nucleic acid templated transcription GO:0097659 181 0.188
regulation of cellular biosynthetic process GO:0031326 245 0.177
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.172
Zebrafish
regulation of gene expression GO:0010468 265 0.164
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.158
Zebrafish
response to hexose GO:0009746 3 0.156
regulation of dna replication GO:0006275 3 0.153
Zebrafish
regulation of dna templated transcription in response to stress GO:0043620 0 0.148
regulation of macromolecule metabolic process GO:0060255 317 0.146
Zebrafish
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.146
cellular biosynthetic process GO:0044249 286 0.140
Zebrafish
blood vessel development GO:0001568 246 0.139
Zebrafish
negative regulation of signaling GO:0023057 96 0.135
Zebrafish
response to oxygen containing compound GO:1901700 55 0.130
organic substance biosynthetic process GO:1901576 289 0.130
Zebrafish
wound healing GO:0042060 90 0.127
cellular response to organic substance GO:0071310 105 0.127
response to cadmium ion GO:0046686 14 0.124
positive regulation of stress activated mapk cascade GO:0032874 3 0.122
vasculature development GO:0001944 278 0.122
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.121
Zebrafish
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.121
aging GO:0007568 2 0.120
regulation of inflammatory response GO:0050727 2 0.120
rna biosynthetic process GO:0032774 181 0.118
response to wounding GO:0009611 116 0.118
regulation of skeletal muscle fiber development GO:0048742 2 0.116
peptidyl serine phosphorylation GO:0018105 1 0.115
nucleic acid metabolic process GO:0090304 244 0.110
Zebrafish
single organism transport GO:0044765 206 0.108
regulation of cell activation GO:0050865 1 0.104
response to bacterium GO:0009617 58 0.103
single organism organelle organization GO:1902589 199 0.102
regulation of multicellular organism growth GO:0040014 4 0.099
Zebrafish
gene expression GO:0010467 252 0.099
regulation of biosynthetic process GO:0009889 250 0.099
Zebrafish
digestive system development GO:0055123 289 0.098
regulation of metabolic process GO:0019222 359 0.096
Zebrafish
regulation of developmental process GO:0050793 247 0.096
Zebrafish
multi organism process GO:0051704 134 0.094
cellular response to endogenous stimulus GO:0071495 68 0.093
regulation of protein complex assembly GO:0043254 3 0.093
reactive oxygen species metabolic process GO:0072593 6 0.092
hemopoiesis GO:0030097 183 0.092
immune system development GO:0002520 191 0.089
negative regulation of response to stimulus GO:0048585 104 0.089
Zebrafish
hormone mediated signaling pathway GO:0009755 9 0.089
protein metabolic process GO:0019538 183 0.087
response to decreased oxygen levels GO:0036293 25 0.086
single organism metabolic process GO:0044710 217 0.086
cell motility GO:0048870 244 0.086
regulation of sodium ion transport GO:0002028 2 0.086
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.084
cell projection morphogenesis GO:0048858 244 0.083
organonitrogen compound metabolic process GO:1901564 74 0.082
response to corticosteroid GO:0031960 1 0.082
multicellular organism growth GO:0035264 4 0.081
Zebrafish
regulation of signaling GO:0023051 235 0.081
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.080
Zebrafish
cellular response to stress GO:0033554 62 0.080
response to endogenous stimulus GO:0009719 83 0.079
negative regulation of biological process GO:0048519 304 0.078
maintenance of location GO:0051235 4 0.078
chronic inflammatory response GO:0002544 1 0.077
post golgi vesicle mediated transport GO:0006892 1 0.077
organelle fusion GO:0048284 3 0.076
regulation of myotube differentiation GO:0010830 2 0.075
regulation of biological quality GO:0065008 263 0.075
single organism nuclear import GO:1902593 3 0.075
regionalization GO:0003002 274 0.075
positive regulation of muscle cell differentiation GO:0051149 1 0.074
nucleobase containing compound biosynthetic process GO:0034654 205 0.073
intracellular signal transduction GO:0035556 85 0.073
negative regulation of cellular metabolic process GO:0031324 77 0.073
Zebrafish
response to amino acid GO:0043200 2 0.071
response to organic cyclic compound GO:0014070 51 0.071
cell death GO:0008219 121 0.071
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.070
Zebrafish
regulation of response to stimulus GO:0048583 269 0.070
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.069
Zebrafish
microtubule polymerization GO:0046785 2 0.068
cytokine mediated signaling pathway GO:0019221 7 0.068
negative regulation of protein complex assembly GO:0031333 1 0.068
response to hypoxia GO:0001666 25 0.067
response to biotic stimulus GO:0009607 97 0.067
positive regulation of biological process GO:0048518 253 0.067
tissue regeneration GO:0042246 74 0.065
neuron projection morphogenesis GO:0048812 161 0.064
single organism membrane fusion GO:0044801 2 0.064
negative regulation of protein phosphorylation GO:0001933 4 0.064
regulation of metal ion transport GO:0010959 4 0.064
peptidyl serine modification GO:0018209 2 0.063
cell migration GO:0016477 237 0.063
positive regulation of rna metabolic process GO:0051254 59 0.062
microtubule depolymerization GO:0007019 1 0.061
cell morphogenesis involved in differentiation GO:0000904 195 0.061
regulation of cellular response to oxidative stress GO:1900407 2 0.061
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.061
response to food GO:0032094 1 0.060
response to alkaloid GO:0043279 2 0.060
amine metabolic process GO:0009308 2 0.060
response to glucose GO:0009749 3 0.059
cellular component movement GO:0006928 335 0.058
regulation of cellular metabolic process GO:0031323 320 0.058
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.057
Zebrafish
negative regulation of protein kinase activity GO:0006469 4 0.056
response to carbohydrate GO:0009743 3 0.056
response to glucocorticoid GO:0051384 1 0.056
response to external stimulus GO:0009605 264 0.056
cellular response to toxic substance GO:0097237 1 0.056
response to abiotic stimulus GO:0009628 122 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.055
generation of neurons GO:0048699 385 0.055
cellular response to organic cyclic compound GO:0071407 38 0.055
response to acidic ph GO:0010447 2 0.055
cell projection organization GO:0030030 284 0.054
response to lipid GO:0033993 60 0.054
regulation of cell cycle GO:0051726 52 0.054
transport GO:0006810 220 0.054
negative regulation of nuclear division GO:0051784 3 0.053
response to metal ion GO:0010038 34 0.052
response to inorganic substance GO:0010035 38 0.052
response to external biotic stimulus GO:0043207 97 0.052
embryo development ending in birth or egg hatching GO:0009792 271 0.052
Zebrafish
gland development GO:0048732 143 0.051
cytoskeleton organization GO:0007010 96 0.051
system process GO:0003008 185 0.051
cellular response to xenobiotic stimulus GO:0071466 35 0.050
death GO:0016265 121 0.050
locomotor rhythm GO:0045475 3 0.050
skin development GO:0043588 54 0.049
positive regulation of cell division GO:0051781 2 0.049
negative regulation of metabolic process GO:0009892 86 0.049
Zebrafish
protein localization to nucleus GO:0034504 3 0.049
lipid storage GO:0019915 1 0.048
regulation of organelle organization GO:0033043 29 0.048
programmed cell death GO:0012501 119 0.047
single organism reproductive process GO:0044702 40 0.047
response to oxidative stress GO:0006979 11 0.046
regulation of protein transport GO:0051223 3 0.045
extrinsic apoptotic signaling pathway GO:0097191 3 0.045
single organism localization GO:1902578 225 0.045
positive regulation of secretion by cell GO:1903532 1 0.045
regulation of cytokine production GO:0001817 3 0.044
secondary metabolic process GO:0019748 3 0.044
g1 s transition of mitotic cell cycle GO:0000082 1 0.044
hepaticobiliary system development GO:0061008 98 0.043
protein import GO:0017038 3 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
Zebrafish
guanosine containing compound metabolic process GO:1901068 4 0.042
liver development GO:0001889 96 0.042
reproductive process GO:0022414 40 0.042
positive regulation of cellular biosynthetic process GO:0031328 68 0.042
positive regulation of metabolic process GO:0009893 108 0.042
regulation of establishment of protein localization GO:0070201 4 0.042
positive regulation of jnk cascade GO:0046330 3 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.042
establishment of localization GO:0051234 244 0.042
embryonic organ development GO:0048568 381 0.041
Zebrafish
pyruvate metabolic process GO:0006090 1 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.041
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.041
regulation of transcription dna templated GO:0006355 213 0.040
Zebrafish
transcription dna templated GO:0006351 181 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.040
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.040
g protein coupled receptor signaling pathway GO:0007186 74 0.040
mitochondrion organization GO:0007005 4 0.040
phosphate containing compound metabolic process GO:0006796 108 0.040
macromolecule modification GO:0043412 111 0.039
response to estrogen GO:0043627 27 0.039
response to copper ion GO:0046688 13 0.039
establishment of protein localization to organelle GO:0072594 4 0.039
angiogenesis GO:0001525 158 0.039
Zebrafish
negative regulation of dna metabolic process GO:0051053 4 0.039
Zebrafish
cell cycle g1 s phase transition GO:0044843 1 0.039
oocyte maturation GO:0001556 4 0.039
axonogenesis GO:0007409 152 0.039
phosphorus metabolic process GO:0006793 109 0.038
positive regulation of inflammatory response GO:0050729 1 0.038
cellular response to external stimulus GO:0071496 2 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
Zebrafish
response to steroid hormone GO:0048545 35 0.038
response to other organism GO:0051707 97 0.038
regulation of response to oxidative stress GO:1902882 2 0.038
transcription from rna polymerase ii promoter GO:0006366 80 0.038
alcohol biosynthetic process GO:0046165 2 0.038
negative regulation of cellular component organization GO:0051129 16 0.038
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.038
Zebrafish
cellular response to radiation GO:0071478 4 0.037
steroid hormone mediated signaling pathway GO:0043401 9 0.037
regeneration GO:0031099 91 0.037
regulation of protein import into nucleus GO:0042306 2 0.037
glucocorticoid metabolic process GO:0008211 2 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
gtp metabolic process GO:0046039 4 0.037
response to oxygen levels GO:0070482 25 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
Zebrafish
small molecule metabolic process GO:0044281 77 0.036
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.036
positive regulation of cellular process GO:0048522 201 0.036
regulation of nucleoside metabolic process GO:0009118 2 0.036
regulation of skeletal muscle tissue development GO:0048641 4 0.036
muscle system process GO:0003012 20 0.036
regulation of cell death GO:0010941 103 0.036
regulation of nucleotide catabolic process GO:0030811 2 0.036
homeostatic process GO:0042592 142 0.035
macromolecular complex subunit organization GO:0043933 74 0.035
regulation of apoptotic process GO:0042981 98 0.035
cell part morphogenesis GO:0032990 246 0.035
negative regulation of cell division GO:0051782 4 0.035
regulation of p38mapk cascade GO:1900744 1 0.035
regulation of cellular component organization GO:0051128 86 0.035
regulation of signal transduction GO:0009966 225 0.035
Zebrafish
osteoclast differentiation GO:0030316 1 0.035
cellular protein metabolic process GO:0044267 129 0.034
positive regulation of catabolic process GO:0009896 4 0.034
positive regulation of gtp catabolic process GO:0033126 1 0.034
protein targeting to nucleus GO:0044744 3 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
Zebrafish
negative regulation of secretion GO:0051048 2 0.034
positive regulation of cell death GO:0010942 29 0.034
larval development GO:0002164 2 0.034
cellular response to steroid hormone stimulus GO:0071383 31 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
cellular response to nutrient levels GO:0031669 2 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.032
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.032
peptide transport GO:0015833 1 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.032
protein polymerization GO:0051258 4 0.032
activation of mapkkk activity GO:0000185 1 0.031
response to nutrient GO:0007584 3 0.031
meiotic cell cycle process GO:1903046 3 0.031
oxoacid metabolic process GO:0043436 31 0.031
regulation of microtubule cytoskeleton organization GO:0070507 3 0.031
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.031
microtubule polymerization or depolymerization GO:0031109 3 0.031
nuclear transport GO:0051169 4 0.030
defense response GO:0006952 47 0.030
neuron projection regeneration GO:0031102 16 0.030
digestive tract development GO:0048565 265 0.030
apoptotic process GO:0006915 116 0.030
striated muscle tissue development GO:0014706 110 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
cellular response to light stimulus GO:0071482 4 0.030
biosynthetic process GO:0009058 294 0.029
Zebrafish
centrosome organization GO:0051297 1 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
regulation of reactive oxygen species metabolic process GO:2000377 2 0.029
glucose homeostasis GO:0042593 1 0.029
cellular response to biotic stimulus GO:0071216 3 0.029
negative regulation of cell communication GO:0010648 96 0.029
Zebrafish
cell death in response to oxidative stress GO:0036473 2 0.028
phosphorylation GO:0016310 69 0.028
cellular protein modification process GO:0006464 100 0.028
negative regulation of kinase activity GO:0033673 4 0.028
localization of cell GO:0051674 244 0.028
gtp catabolic process GO:0006184 2 0.028
somite development GO:0061053 96 0.028
regulation of cell communication GO:0010646 232 0.028
Zebrafish
protein complex disassembly GO:0043241 1 0.028
cellular response to extracellular stimulus GO:0031668 2 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
zymogen activation GO:0031638 3 0.027
cellular biogenic amine metabolic process GO:0006576 2 0.027
cellular component morphogenesis GO:0032989 336 0.027
carboxylic acid metabolic process GO:0019752 22 0.026
membrane fusion GO:0061025 2 0.026
astrocyte differentiation GO:0048708 1 0.026
positive regulation of secretion GO:0051047 1 0.026
regulation of jak stat cascade GO:0046425 3 0.026
ectoderm formation GO:0001705 2 0.026
cell cycle GO:0007049 93 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.026
nuclear import GO:0051170 3 0.026
response to arsenic containing substance GO:0046685 5 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
ion homeostasis GO:0050801 41 0.025
negative regulation of mitosis GO:0045839 3 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
monocyte differentiation GO:0030224 2 0.025
cellular component disassembly GO:0022411 1 0.025
cellular response to hormone stimulus GO:0032870 39 0.025
growth GO:0040007 174 0.025
Zebrafish
positive regulation of gtpase activity GO:0043547 1 0.025
regulation of muscle hypertrophy GO:0014743 2 0.025
negative regulation of ras protein signal transduction GO:0046580 1 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
response to immobilization stress GO:0035902 1 0.025
positive regulation of cytokine production GO:0001819 2 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
organelle organization GO:0006996 227 0.025
neuron differentiation GO:0030182 353 0.024
response to molecule of bacterial origin GO:0002237 14 0.024
negative regulation of gene expression GO:0010629 65 0.024
protein modification process GO:0036211 100 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
epithelial cell migration GO:0010631 25 0.024
positive regulation of chronic inflammatory response GO:0002678 1 0.024
meiotic nuclear division GO:0007126 4 0.024
negative regulation of secretion by cell GO:1903531 2 0.024
cellular response to oxygen containing compound GO:1901701 20 0.023
cell proliferation GO:0008283 80 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
sphingolipid biosynthetic process GO:0030148 2 0.023
response to vitamin GO:0033273 3 0.023
response to temperature stimulus GO:0009266 15 0.023
negative regulation of cellular biosynthetic process GO:0031327 55 0.023
Zebrafish
nitric oxide biosynthetic process GO:0006809 2 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
Zebrafish
hormone transport GO:0009914 2 0.023
regulation of locomotion GO:0040012 55 0.023
positive regulation of biosynthetic process GO:0009891 68 0.022
antimicrobial humoral response GO:0019730 2 0.022
positive regulation of endopeptidase activity GO:0010950 10 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.022
oxidative demethylation GO:0070989 1 0.022
immune system process GO:0002376 241 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
Zebrafish
protein import into nucleus GO:0006606 3 0.022
muscle cell differentiation GO:0042692 139 0.022
organic acid metabolic process GO:0006082 31 0.022
regulation of response to interferon gamma GO:0060330 1 0.022
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.022
actin filament based process GO:0030029 64 0.021
regulation of cell division GO:0051302 12 0.021
somitogenesis GO:0001756 87 0.021
alpha amino acid metabolic process GO:1901605 3 0.021
response to methylmercury GO:0051597 11 0.021
regulation of programmed cell death GO:0043067 101 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
protein localization to plasma membrane GO:0072659 1 0.021
regulation of gtpase activity GO:0043087 2 0.021
regulation of intracellular protein transport GO:0033157 3 0.020
cellular response to oxygen levels GO:0071453 1 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
regulation of blood vessel endothelial cell migration GO:0043535 5 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
insulin like growth factor receptor signaling pathway GO:0048009 4 0.020
Zebrafish
response to hormone GO:0009725 48 0.020
regulation of oxidative stress induced cell death GO:1903201 2 0.020
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.020
rna metabolic process GO:0016070 219 0.020
positive regulation of neuron death GO:1901216 1 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
Zebrafish
response to alcohol GO:0097305 14 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
positive regulation of programmed cell death GO:0043068 29 0.020
blood vessel endothelial cell migration GO:0043534 18 0.020
regulation of cell projection organization GO:0031344 44 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
positive regulation of gliogenesis GO:0014015 2 0.020
organonitrogen compound biosynthetic process GO:1901566 47 0.019
skeletal system development GO:0001501 181 0.019
Zebrafish
cell morphogenesis GO:0000902 289 0.019
cytokinesis GO:0000910 3 0.019
developmental growth GO:0048589 166 0.019
Zebrafish
regulation of hormone secretion GO:0046883 2 0.019
response to ph GO:0009268 2 0.019
regulation of cell migration GO:0030334 40 0.019
circulatory system process GO:0003013 87 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
regulation of cellular ph GO:0030641 1 0.019
xenobiotic metabolic process GO:0006805 4 0.019
transcription from rna polymerase iii promoter GO:0006383 1 0.019
positive regulation of epithelial cell migration GO:0010634 2 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
regulation of binding GO:0051098 3 0.019
microtubule organizing center organization GO:0031023 1 0.019
regulation of molecular function GO:0065009 70 0.019
regulation of organ growth GO:0046620 3 0.018
regulation of chronic inflammatory response GO:0002676 1 0.018
positive regulation of immune effector process GO:0002699 3 0.018
response to xenobiotic stimulus GO:0009410 45 0.018
cell substrate adhesion GO:0031589 4 0.018
fat soluble vitamin metabolic process GO:0006775 4 0.018
protein dephosphorylation GO:0006470 3 0.018
behavior GO:0007610 74 0.018
cell activation GO:0001775 16 0.018
protein acetylation GO:0006473 2 0.018
regulation of mitotic cell cycle GO:0007346 25 0.018
compound eye development GO:0048749 2 0.018
protein secretion GO:0009306 1 0.018
response to dexamethasone GO:0071548 1 0.018
regulation of cell projection assembly GO:0060491 4 0.018
positive regulation of transport GO:0051050 2 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
regulation of cell growth GO:0001558 29 0.018
catechol containing compound biosynthetic process GO:0009713 2 0.018
cellular response to starvation GO:0009267 1 0.018
membrane lipid biosynthetic process GO:0046467 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
organ regeneration GO:0031100 1 0.018
p38mapk cascade GO:0038066 1 0.018
regulation of cytoskeleton organization GO:0051493 11 0.018
cellular response to organonitrogen compound GO:0071417 5 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
purine containing compound metabolic process GO:0072521 29 0.017
regulation of protein targeting GO:1903533 2 0.017
positive regulation of molecular function GO:0044093 33 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
negative regulation of locomotion GO:0040013 18 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
regulation of reproductive process GO:2000241 4 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
positive regulation of gene expression GO:0010628 71 0.017
stem cell maintenance GO:0019827 4 0.017
pathway restricted smad protein phosphorylation GO:0060389 1 0.017
positive regulation of developmental process GO:0051094 50 0.017
chordate embryonic development GO:0043009 271 0.017
Zebrafish
response to mechanical stimulus GO:0009612 24 0.017
nucleoside phosphate metabolic process GO:0006753 28 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
cytokine metabolic process GO:0042107 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
negative regulation of intracellular signal transduction GO:1902532 22 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular amine metabolic process GO:0044106 2 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
cellular component biogenesis GO:0044085 178 0.017
cellular response to growth factor stimulus GO:0071363 39 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
Zebrafish
blood coagulation GO:0007596 12 0.016
regulation of glial cell proliferation GO:0060251 4 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
positive regulation of type i interferon production GO:0032481 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
peptide metabolic process GO:0006518 1 0.016
negative regulation of bmp signaling pathway GO:0030514 13 0.016
Zebrafish
negative regulation of cytokine production GO:0001818 1 0.016
regulation of receptor activity GO:0010469 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
regulation of body fluid levels GO:0050878 16 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
spinal cord radial glial cell differentiation GO:0021531 2 0.016
cell differentiation in spinal cord GO:0021515 40 0.016
regulation of protein binding GO:0043393 3 0.016
cellular component assembly GO:0022607 170 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
negative regulation of protein transport GO:0051224 3 0.016
cell substrate junction assembly GO:0007044 2 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
regulation of cytokine biosynthetic process GO:0042035 1 0.015
neuronal stem cell maintenance GO:0097150 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
cardiac atrium development GO:0003230 4 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
immunoglobulin production GO:0002377 1 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Zebrafish
regulation of dendrite development GO:0050773 3 0.015
negative regulation of epithelial cell migration GO:0010633 1 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
organic substance transport GO:0071702 58 0.015

igfbp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.046
cancer DOID:162 0 0.046
organ system cancer DOID:0050686 0 0.045
gastrointestinal system cancer DOID:3119 0 0.028
disease of metabolism DOID:0014667 0 0.026
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022
eye and adnexa disease DOID:1492 0 0.022
retinal disease DOID:5679 0 0.022
sensory system disease DOID:0050155 0 0.022