Danio rerio

17 known processes

igfbp1a

insulin-like growth factor binding protein 1a

(Aliases: igfbp1,cb656,IGFBP-1)

igfbp1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to stress GO:0006950 263 0.752
response to transition metal nanoparticle GO:1990267 28 0.698
response to drug GO:0042493 3 0.478
response to monosaccharide GO:0034284 3 0.475
response to chemical GO:0042221 320 0.375
response to organic substance GO:0010033 153 0.350
organic cyclic compound metabolic process GO:1901360 301 0.341
Zebrafish
response to antibiotic GO:0046677 1 0.303
cognition GO:0050890 1 0.292
positive regulation of cell cycle GO:0045787 3 0.282
blood vessel morphogenesis GO:0048514 216 0.272
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.265
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.261
Zebrafish
negative regulation of cellular process GO:0048523 283 0.254
regulation of multicellular organismal process GO:0051239 277 0.249
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.247
signal transduction GO:0007165 455 0.225
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.223
Zebrafish
heterocycle metabolic process GO:0046483 290 0.222
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.221
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.211
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.191
nucleic acid templated transcription GO:0097659 181 0.188
regulation of cellular biosynthetic process GO:0031326 245 0.177
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.172
Zebrafish
regulation of gene expression GO:0010468 265 0.164
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.158
Zebrafish
response to hexose GO:0009746 3 0.156
regulation of dna replication GO:0006275 3 0.153
Zebrafish
regulation of dna templated transcription in response to stress GO:0043620 0 0.148
regulation of macromolecule metabolic process GO:0060255 317 0.146
Zebrafish
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.146
cellular biosynthetic process GO:0044249 286 0.140
Zebrafish
blood vessel development GO:0001568 246 0.139
Zebrafish
negative regulation of signaling GO:0023057 96 0.135
Zebrafish
response to oxygen containing compound GO:1901700 55 0.130
organic substance biosynthetic process GO:1901576 289 0.130
Zebrafish
wound healing GO:0042060 90 0.127
cellular response to organic substance GO:0071310 105 0.127
response to cadmium ion GO:0046686 14 0.124
positive regulation of stress activated mapk cascade GO:0032874 3 0.122
vasculature development GO:0001944 278 0.122
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.121
Zebrafish
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.121
aging GO:0007568 2 0.120
regulation of inflammatory response GO:0050727 2 0.120
rna biosynthetic process GO:0032774 181 0.118
response to wounding GO:0009611 116 0.118
regulation of skeletal muscle fiber development GO:0048742 2 0.116
peptidyl serine phosphorylation GO:0018105 1 0.115
nucleic acid metabolic process GO:0090304 244 0.110
Zebrafish
single organism transport GO:0044765 206 0.108
regulation of cell activation GO:0050865 1 0.104
response to bacterium GO:0009617 58 0.103
single organism organelle organization GO:1902589 199 0.102
regulation of multicellular organism growth GO:0040014 4 0.099
Zebrafish
gene expression GO:0010467 252 0.099
regulation of biosynthetic process GO:0009889 250 0.099
Zebrafish
digestive system development GO:0055123 289 0.098
regulation of metabolic process GO:0019222 359 0.096
Zebrafish
regulation of developmental process GO:0050793 247 0.096
Zebrafish
multi organism process GO:0051704 134 0.094
cellular response to endogenous stimulus GO:0071495 68 0.093
regulation of protein complex assembly GO:0043254 3 0.093
reactive oxygen species metabolic process GO:0072593 6 0.092
hemopoiesis GO:0030097 183 0.092
immune system development GO:0002520 191 0.089
negative regulation of response to stimulus GO:0048585 104 0.089
Zebrafish
hormone mediated signaling pathway GO:0009755 9 0.089
protein metabolic process GO:0019538 183 0.087
response to decreased oxygen levels GO:0036293 25 0.086
single organism metabolic process GO:0044710 217 0.086
cell motility GO:0048870 244 0.086
regulation of sodium ion transport GO:0002028 2 0.086
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.084
cell projection morphogenesis GO:0048858 244 0.083
organonitrogen compound metabolic process GO:1901564 74 0.082
response to corticosteroid GO:0031960 1 0.082
multicellular organism growth GO:0035264 4 0.081
Zebrafish
regulation of signaling GO:0023051 235 0.081
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.080
Zebrafish
cellular response to stress GO:0033554 62 0.080
response to endogenous stimulus GO:0009719 83 0.079
negative regulation of biological process GO:0048519 304 0.078
maintenance of location GO:0051235 4 0.078
chronic inflammatory response GO:0002544 1 0.077
post golgi vesicle mediated transport GO:0006892 1 0.077
organelle fusion GO:0048284 3 0.076
regulation of myotube differentiation GO:0010830 2 0.075
regulation of biological quality GO:0065008 263 0.075
single organism nuclear import GO:1902593 3 0.075
regionalization GO:0003002 274 0.075
positive regulation of muscle cell differentiation GO:0051149 1 0.074
nucleobase containing compound biosynthetic process GO:0034654 205 0.073
intracellular signal transduction GO:0035556 85 0.073
negative regulation of cellular metabolic process GO:0031324 77 0.073
Zebrafish
response to amino acid GO:0043200 2 0.071
response to organic cyclic compound GO:0014070 51 0.071
cell death GO:0008219 121 0.071
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.070
Zebrafish
regulation of response to stimulus GO:0048583 269 0.070
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.069
Zebrafish
microtubule polymerization GO:0046785 2 0.068
cytokine mediated signaling pathway GO:0019221 7 0.068
negative regulation of protein complex assembly GO:0031333 1 0.068
response to hypoxia GO:0001666 25 0.067
response to biotic stimulus GO:0009607 97 0.067
positive regulation of biological process GO:0048518 253 0.067
tissue regeneration GO:0042246 74 0.065
neuron projection morphogenesis GO:0048812 161 0.064
single organism membrane fusion GO:0044801 2 0.064
negative regulation of protein phosphorylation GO:0001933 4 0.064
regulation of metal ion transport GO:0010959 4 0.064
peptidyl serine modification GO:0018209 2 0.063
cell migration GO:0016477 237 0.063
positive regulation of rna metabolic process GO:0051254 59 0.062
microtubule depolymerization GO:0007019 1 0.061
cell morphogenesis involved in differentiation GO:0000904 195 0.061
regulation of cellular response to oxidative stress GO:1900407 2 0.061
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.061
response to food GO:0032094 1 0.060
response to alkaloid GO:0043279 2 0.060
amine metabolic process GO:0009308 2 0.060
response to glucose GO:0009749 3 0.059
cellular component movement GO:0006928 335 0.058
regulation of cellular metabolic process GO:0031323 320 0.058
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.057
Zebrafish
negative regulation of protein kinase activity GO:0006469 4 0.056
response to carbohydrate GO:0009743 3 0.056
response to glucocorticoid GO:0051384 1 0.056
response to external stimulus GO:0009605 264 0.056
cellular response to toxic substance GO:0097237 1 0.056
response to abiotic stimulus GO:0009628 122 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.055
generation of neurons GO:0048699 385 0.055
cellular response to organic cyclic compound GO:0071407 38 0.055
response to acidic ph GO:0010447 2 0.055
cell projection organization GO:0030030 284 0.054
response to lipid GO:0033993 60 0.054
regulation of cell cycle GO:0051726 52 0.054
transport GO:0006810 220 0.054
negative regulation of nuclear division GO:0051784 3 0.053
response to metal ion GO:0010038 34 0.052
response to inorganic substance GO:0010035 38 0.052
response to external biotic stimulus GO:0043207 97 0.052
embryo development ending in birth or egg hatching GO:0009792 271 0.052
Zebrafish
gland development GO:0048732 143 0.051
cytoskeleton organization GO:0007010 96 0.051
system process GO:0003008 185 0.051
cellular response to xenobiotic stimulus GO:0071466 35 0.050
death GO:0016265 121 0.050
locomotor rhythm GO:0045475 3 0.050
skin development GO:0043588 54 0.049
positive regulation of cell division GO:0051781 2 0.049
negative regulation of metabolic process GO:0009892 86 0.049
Zebrafish
protein localization to nucleus GO:0034504 3 0.049
lipid storage GO:0019915 1 0.048
regulation of organelle organization GO:0033043 29 0.048
programmed cell death GO:0012501 119 0.047
single organism reproductive process GO:0044702 40 0.047
response to oxidative stress GO:0006979 11 0.046
regulation of protein transport GO:0051223 3 0.045
extrinsic apoptotic signaling pathway GO:0097191 3 0.045
single organism localization GO:1902578 225 0.045
positive regulation of secretion by cell GO:1903532 1 0.045
regulation of cytokine production GO:0001817 3 0.044
secondary metabolic process GO:0019748 3 0.044
g1 s transition of mitotic cell cycle GO:0000082 1 0.044
hepaticobiliary system development GO:0061008 98 0.043
protein import GO:0017038 3 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
Zebrafish
guanosine containing compound metabolic process GO:1901068 4 0.042
liver development GO:0001889 96 0.042
reproductive process GO:0022414 40 0.042
positive regulation of cellular biosynthetic process GO:0031328 68 0.042
positive regulation of metabolic process GO:0009893 108 0.042
regulation of establishment of protein localization GO:0070201 4 0.042
positive regulation of jnk cascade GO:0046330 3 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.042
establishment of localization GO:0051234 244 0.042
embryonic organ development GO:0048568 381 0.041
Zebrafish
pyruvate metabolic process GO:0006090 1 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.041
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.041
regulation of transcription dna templated GO:0006355 213 0.040
Zebrafish
transcription dna templated GO:0006351 181 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.040
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.040
g protein coupled receptor signaling pathway GO:0007186 74 0.040
mitochondrion organization GO:0007005 4 0.040
phosphate containing compound metabolic process GO:0006796 108 0.040
macromolecule modification GO:0043412 111 0.039
response to estrogen GO:0043627 27 0.039
response to copper ion GO:0046688 13 0.039
establishment of protein localization to organelle GO:0072594 4 0.039
angiogenesis GO:0001525 158 0.039
Zebrafish
negative regulation of dna metabolic process GO:0051053 4 0.039
Zebrafish
cell cycle g1 s phase transition GO:0044843 1 0.039
oocyte maturation GO:0001556 4 0.039
axonogenesis GO:0007409 152 0.039
phosphorus metabolic process GO:0006793 109 0.038
positive regulation of inflammatory response GO:0050729 1 0.038
cellular response to external stimulus GO:0071496 2 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
Zebrafish
response to steroid hormone GO:0048545 35 0.038
response to other organism GO:0051707 97 0.038
regulation of response to oxidative stress GO:1902882 2 0.038
transcription from rna polymerase ii promoter GO:0006366 80 0.038
alcohol biosynthetic process GO:0046165 2 0.038
negative regulation of cellular component organization GO:0051129 16 0.038
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.038
Zebrafish
cellular response to radiation GO:0071478 4 0.037
steroid hormone mediated signaling pathway GO:0043401 9 0.037
regeneration GO:0031099 91 0.037
regulation of protein import into nucleus GO:0042306 2 0.037
glucocorticoid metabolic process GO:0008211 2 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
gtp metabolic process GO:0046039 4 0.037
response to oxygen levels GO:0070482 25 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
Zebrafish
small molecule metabolic process GO:0044281 77 0.036
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.036
positive regulation of cellular process GO:0048522 201 0.036
regulation of nucleoside metabolic process GO:0009118 2 0.036
regulation of skeletal muscle tissue development GO:0048641 4 0.036
muscle system process GO:0003012 20 0.036
regulation of cell death GO:0010941 103 0.036
regulation of nucleotide catabolic process GO:0030811 2 0.036
homeostatic process GO:0042592 142 0.035
macromolecular complex subunit organization GO:0043933 74 0.035
regulation of apoptotic process GO:0042981 98 0.035
cell part morphogenesis GO:0032990 246 0.035
negative regulation of cell division GO:0051782 4 0.035
regulation of p38mapk cascade GO:1900744 1 0.035
regulation of cellular component organization GO:0051128 86 0.035
regulation of signal transduction GO:0009966 225 0.035
Zebrafish
osteoclast differentiation GO:0030316 1 0.035
cellular protein metabolic process GO:0044267 129 0.034
positive regulation of catabolic process GO:0009896 4 0.034
positive regulation of gtp catabolic process GO:0033126 1 0.034
protein targeting to nucleus GO:0044744 3 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
Zebrafish
negative regulation of secretion GO:0051048 2 0.034
positive regulation of cell death GO:0010942 29 0.034
larval development GO:0002164 2 0.034
cellular response to steroid hormone stimulus GO:0071383 31 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
cellular response to nutrient levels GO:0031669 2 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.032
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.032
peptide transport GO:0015833 1 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.032
protein polymerization GO:0051258 4 0.032
activation of mapkkk activity GO:0000185 1 0.031
response to nutrient GO:0007584 3 0.031
meiotic cell cycle process GO:1903046 3 0.031
oxoacid metabolic process GO:0043436 31 0.031
regulation of microtubule cytoskeleton organization GO:0070507 3 0.031
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.031
microtubule polymerization or depolymerization GO:0031109 3 0.031
nuclear transport GO:0051169 4 0.030
defense response GO:0006952 47 0.030
neuron projection regeneration GO:0031102 16 0.030
digestive tract development GO:0048565 265 0.030
apoptotic process GO:0006915 116 0.030
striated muscle tissue development GO:0014706 110 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
cellular response to light stimulus GO:0071482 4 0.030
biosynthetic process GO:0009058 294 0.029
Zebrafish
centrosome organization GO:0051297 1 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
regulation of reactive oxygen species metabolic process GO:2000377 2 0.029
glucose homeostasis GO:0042593 1 0.029
cellular response to biotic stimulus GO:0071216 3 0.029
negative regulation of cell communication GO:0010648 96 0.029
Zebrafish
cell death in response to oxidative stress GO:0036473 2 0.028
phosphorylation GO:0016310 69 0.028
cellular protein modification process GO:0006464 100 0.028
negative regulation of kinase activity GO:0033673 4 0.028
localization of cell GO:0051674 244 0.028
gtp catabolic process GO:0006184 2 0.028
somite development GO:0061053 96 0.028
regulation of cell communication GO:0010646 232 0.028
Zebrafish
protein complex disassembly GO:0043241 1 0.028
cellular response to extracellular stimulus GO:0031668 2 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
zymogen activation GO:0031638 3 0.027
cellular biogenic amine metabolic process GO:0006576 2 0.027
cellular component morphogenesis GO:0032989 336 0.027
carboxylic acid metabolic process GO:0019752 22 0.026
membrane fusion GO:0061025 2 0.026
astrocyte differentiation GO:0048708 1 0.026
positive regulation of secretion GO:0051047 1 0.026
regulation of jak stat cascade GO:0046425 3 0.026
ectoderm formation GO:0001705 2 0.026
cell cycle GO:0007049 93 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.026
nuclear import GO:0051170 3 0.026
response to arsenic containing substance GO:0046685 5 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
ion homeostasis GO:0050801 41 0.025
negative regulation of mitosis GO:0045839 3 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
monocyte differentiation GO:0030224 2 0.025
cellular component disassembly GO:0022411 1 0.025
cellular response to hormone stimulus GO:0032870 39 0.025
growth GO:0040007 174 0.025
Zebrafish
positive regulation of gtpase activity GO:0043547 1 0.025
regulation of muscle hypertrophy GO:0014743 2 0.025
negative regulation of ras protein signal transduction GO:0046580 1 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
response to immobilization stress GO:0035902 1 0.025
positive regulation of cytokine production GO:0001819 2 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
organelle organization GO:0006996 227 0.025
neuron differentiation GO:0030182 353 0.024
response to molecule of bacterial origin GO:0002237 14 0.024
negative regulation of gene expression GO:0010629 65 0.024
protein modification process GO:0036211 100 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
epithelial cell migration GO:0010631 25 0.024
positive regulation of chronic inflammatory response GO:0002678 1 0.024
meiotic nuclear division GO:0007126 4 0.024
negative regulation of secretion by cell GO:1903531 2 0.024
cellular response to oxygen containing compound GO:1901701 20 0.023
cell proliferation GO:0008283 80 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
sphingolipid biosynthetic process GO:0030148 2 0.023
response to vitamin GO:0033273 3 0.023
response to temperature stimulus GO:0009266 15 0.023
negative regulation of cellular biosynthetic process GO:0031327 55 0.023
Zebrafish
nitric oxide biosynthetic process GO:0006809 2 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
Zebrafish
hormone transport GO:0009914 2 0.023
regulation of locomotion GO:0040012 55 0.023
positive regulation of biosynthetic process GO:0009891 68 0.022
antimicrobial humoral response GO:0019730 2 0.022
positive regulation of endopeptidase activity GO:0010950 10 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.022
oxidative demethylation GO:0070989 1 0.022
immune system process GO:0002376 241 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
Zebrafish
protein import into nucleus GO:0006606 3 0.022
muscle cell differentiation GO:0042692 139 0.022
organic acid metabolic process GO:0006082 31 0.022
regulation of response to interferon gamma GO:0060330 1 0.022
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.022
actin filament based process GO:0030029 64 0.021
regulation of cell division GO:0051302 12 0.021
somitogenesis GO:0001756 87 0.021
alpha amino acid metabolic process GO:1901605 3 0.021
response to methylmercury GO:0051597 11 0.021
regulation of programmed cell death GO:0043067 101 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
protein localization to plasma membrane GO:0072659 1 0.021
regulation of gtpase activity GO:0043087 2 0.021
regulation of intracellular protein transport GO:0033157 3 0.020
cellular response to oxygen levels GO:0071453 1 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
regulation of blood vessel endothelial cell migration GO:0043535 5 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
insulin like growth factor receptor signaling pathway GO:0048009 4 0.020
Zebrafish
response to hormone GO:0009725 48 0.020
regulation of oxidative stress induced cell death GO:1903201 2 0.020
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.020
rna metabolic process GO:0016070 219 0.020
positive regulation of neuron death GO:1901216 1 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
Zebrafish
response to alcohol GO:0097305 14 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
positive regulation of programmed cell death GO:0043068 29 0.020
blood vessel endothelial cell migration GO:0043534 18 0.020
regulation of cell projection organization GO:0031344 44 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
positive regulation of gliogenesis GO:0014015 2 0.020
organonitrogen compound biosynthetic process GO:1901566 47 0.019
skeletal system development GO:0001501 181 0.019
Zebrafish
cell morphogenesis GO:0000902 289 0.019
cytokinesis GO:0000910 3 0.019
developmental growth GO:0048589 166 0.019
Zebrafish
regulation of hormone secretion GO:0046883 2 0.019
response to ph GO:0009268 2 0.019
regulation of cell migration GO:0030334 40 0.019
circulatory system process GO:0003013 87 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
regulation of cellular ph GO:0030641 1 0.019
xenobiotic metabolic process GO:0006805 4 0.019
transcription from rna polymerase iii promoter GO:0006383 1 0.019
positive regulation of epithelial cell migration GO:0010634 2 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
regulation of binding GO:0051098 3 0.019
microtubule organizing center organization GO:0031023 1 0.019
regulation of molecular function GO:0065009 70 0.019
regulation of organ growth GO:0046620 3 0.018
regulation of chronic inflammatory response GO:0002676 1 0.018
positive regulation of immune effector process GO:0002699 3 0.018
response to xenobiotic stimulus GO:0009410 45 0.018
cell substrate adhesion GO:0031589 4 0.018
fat soluble vitamin metabolic process GO:0006775 4 0.018
protein dephosphorylation GO:0006470 3 0.018
behavior GO:0007610 74 0.018
cell activation GO:0001775 16 0.018
protein acetylation GO:0006473 2 0.018
regulation of mitotic cell cycle GO:0007346 25 0.018
compound eye development GO:0048749 2 0.018
protein secretion GO:0009306 1 0.018
response to dexamethasone GO:0071548 1 0.018
regulation of cell projection assembly GO:0060491 4 0.018
positive regulation of transport GO:0051050 2 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
regulation of cell growth GO:0001558 29 0.018
catechol containing compound biosynthetic process GO:0009713 2 0.018
cellular response to starvation GO:0009267 1 0.018
membrane lipid biosynthetic process GO:0046467 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
organ regeneration GO:0031100 1 0.018
p38mapk cascade GO:0038066 1 0.018
regulation of cytoskeleton organization GO:0051493 11 0.018
cellular response to organonitrogen compound GO:0071417 5 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
purine containing compound metabolic process GO:0072521 29 0.017
regulation of protein targeting GO:1903533 2 0.017
positive regulation of molecular function GO:0044093 33 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
negative regulation of locomotion GO:0040013 18 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
regulation of reproductive process GO:2000241 4 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
positive regulation of gene expression GO:0010628 71 0.017
stem cell maintenance GO:0019827 4 0.017
pathway restricted smad protein phosphorylation GO:0060389 1 0.017
positive regulation of developmental process GO:0051094 50 0.017
chordate embryonic development GO:0043009 271 0.017
Zebrafish
response to mechanical stimulus GO:0009612 24 0.017
nucleoside phosphate metabolic process GO:0006753 28 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
cytokine metabolic process GO:0042107 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
negative regulation of intracellular signal transduction GO:1902532 22 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular amine metabolic process GO:0044106 2 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
cellular component biogenesis GO:0044085 178 0.017
cellular response to growth factor stimulus GO:0071363 39 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
Zebrafish
blood coagulation GO:0007596 12 0.016
regulation of glial cell proliferation GO:0060251 4 0.016
positive regulation of apoptotic process GO:0043065 29 0.016
positive regulation of type i interferon production GO:0032481 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
peptide metabolic process GO:0006518 1 0.016
negative regulation of bmp signaling pathway GO:0030514 13 0.016
Zebrafish
negative regulation of cytokine production GO:0001818 1 0.016
regulation of receptor activity GO:0010469 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
regulation of body fluid levels GO:0050878 16 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
spinal cord radial glial cell differentiation GO:0021531 2 0.016
cell differentiation in spinal cord GO:0021515 40 0.016
regulation of protein binding GO:0043393 3 0.016
cellular component assembly GO:0022607 170 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
negative regulation of protein transport GO:0051224 3 0.016
cell substrate junction assembly GO:0007044 2 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
regulation of cytokine biosynthetic process GO:0042035 1 0.015
neuronal stem cell maintenance GO:0097150 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
cardiac atrium development GO:0003230 4 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
immunoglobulin production GO:0002377 1 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Zebrafish
regulation of dendrite development GO:0050773 3 0.015
negative regulation of epithelial cell migration GO:0010633 1 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
organic substance transport GO:0071702 58 0.015

igfbp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
organ system cancer DOID:0050686 0 0.045
gastrointestinal system cancer DOID:3119 0 0.028
disease of metabolism DOID:0014667 0 0.026
retinal disease DOID:5679 0 0.022
sensory system disease DOID:0050155 0 0.022
disease of anatomical entity DOID:7 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022