Danio rerio

100 known processes

igfbp2a

insulin-like growth factor binding protein 2a

(Aliases: igfbp2,MGC76823,MGC65741,igfbp2b,MGC174445)

igfbp2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ morphogenesis GO:0090596 200 0.393
Zebrafish
larval development GO:0002164 2 0.204
muscle cell development GO:0055001 115 0.185
vasculature development GO:0001944 278 0.150
response to xenobiotic stimulus GO:0009410 45 0.145
camera type eye development GO:0043010 222 0.139
generation of neurons GO:0048699 385 0.114
regulation of retina development in camera type eye GO:1902866 2 0.108
blood vessel development GO:0001568 246 0.108
striated muscle cell differentiation GO:0051146 129 0.097
eye development GO:0001654 277 0.091
striated muscle cell development GO:0055002 108 0.086
eye morphogenesis GO:0048592 144 0.085
cellular response to xenobiotic stimulus GO:0071466 35 0.084
cellular response to prostaglandin stimulus GO:0071379 3 0.084
negative regulation of cellular process GO:0048523 283 0.080
muscle cell differentiation GO:0042692 139 0.074
phagocytosis engulfment GO:0006911 1 0.067
dicarboxylic acid metabolic process GO:0043648 1 0.066
negative regulation of biological process GO:0048519 304 0.060
positive regulation of cell activation GO:0050867 1 0.057
Human
response to lipid GO:0033993 60 0.052
cell morphogenesis GO:0000902 289 0.052
positive regulation of cell adhesion GO:0045785 1 0.051
positive regulation of wound healing GO:0090303 1 0.049
specification of symmetry GO:0009799 204 0.046
heart development GO:0007507 313 0.045
positive regulation of catabolic process GO:0009896 4 0.044
regulation of wound healing GO:0061041 2 0.043
multicellular organism growth GO:0035264 4 0.042
digestive tract development GO:0048565 265 0.041
cerebellar granular layer development GO:0021681 3 0.040
cell substrate adhesion GO:0031589 4 0.039
sensory organ development GO:0007423 393 0.038
Zebrafish
superoxide metabolic process GO:0006801 2 0.038
response to chemical GO:0042221 320 0.037
cell matrix adhesion GO:0007160 4 0.036
digestive system development GO:0055123 289 0.036
regulation of reactive oxygen species metabolic process GO:2000377 2 0.035
response to external stimulus GO:0009605 264 0.035
cellular amino acid biosynthetic process GO:0008652 2 0.035
camera type eye morphogenesis GO:0048593 108 0.034
muscle attachment GO:0016203 9 0.033
blood vessel morphogenesis GO:0048514 216 0.032
muscle fiber development GO:0048747 52 0.032
chordate embryonic development GO:0043009 271 0.032
Zebrafish
response to organic substance GO:0010033 153 0.032
regulation of metal ion transport GO:0010959 4 0.031
membrane invagination GO:0010324 1 0.029
alcohol biosynthetic process GO:0046165 2 0.029
head development GO:0060322 303 0.029
reactive oxygen species metabolic process GO:0072593 6 0.029
maintenance of location GO:0051235 4 0.028
glucocorticoid metabolic process GO:0008211 2 0.028
cellular amine metabolic process GO:0044106 2 0.026
carbon dioxide transmembrane transport GO:0035378 1 0.026
axon ensheathment in central nervous system GO:0032291 2 0.026
neuron differentiation GO:0030182 353 0.025
aging GO:0007568 2 0.025
autophagy GO:0006914 4 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
negative regulation of signal transduction GO:0009968 94 0.025
Zebrafish
sprouting angiogenesis GO:0002040 53 0.024
regulation of hemostasis GO:1900046 1 0.024
response to wounding GO:0009611 116 0.023
determination of bilateral symmetry GO:0009855 204 0.023
astrocyte differentiation GO:0048708 1 0.023
regulation of cell activation GO:0050865 1 0.023
Human
germ line stem cell maintenance GO:0030718 2 0.022
brain development GO:0007420 293 0.022
muscle structure development GO:0061061 196 0.022
neuron projection development GO:0031175 180 0.021
neuron development GO:0048666 262 0.021
liver development GO:0001889 96 0.021
multicellular organismal metabolic process GO:0044236 2 0.020
meiotic nuclear division GO:0007126 4 0.020
fat soluble vitamin metabolic process GO:0006775 4 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
regulation of cell substrate adhesion GO:0010810 1 0.019
cellular component morphogenesis GO:0032989 336 0.019
cellular component assembly GO:0022607 170 0.019
lens development in camera type eye GO:0002088 22 0.019
regulation of neurogenesis GO:0050767 87 0.018
regulation of signal transduction GO:0009966 225 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
carboxylic acid biosynthetic process GO:0046394 12 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
multicellular organismal signaling GO:0035637 22 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
cellular amide metabolic process GO:0043603 4 0.016
pyruvate metabolic process GO:0006090 1 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
hormone metabolic process GO:0042445 19 0.016
response to ketone GO:1901654 1 0.016
catecholamine metabolic process GO:0006584 2 0.016
rna biosynthetic process GO:0032774 181 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.016
gland development GO:0048732 143 0.016
response to abiotic stimulus GO:0009628 122 0.015
Zebrafish
regulation of developmental process GO:0050793 247 0.015
carbon dioxide transport GO:0015670 3 0.015
post embryonic organ development GO:0048569 4 0.015
gliogenesis GO:0042063 45 0.015
response to hormone GO:0009725 48 0.015
organic acid biosynthetic process GO:0016053 12 0.015
regulation of response to stimulus GO:0048583 269 0.015
organelle organization GO:0006996 227 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
regeneration GO:0031099 91 0.015
gtp catabolic process GO:0006184 2 0.014
neuroblast proliferation GO:0007405 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
response to metal ion GO:0010038 34 0.014
lipid storage GO:0019915 1 0.014
lens fiber cell development GO:0070307 3 0.014
glial cell development GO:0021782 20 0.014
venous blood vessel morphogenesis GO:0048845 3 0.014
skeletal system morphogenesis GO:0048705 102 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of nervous system development GO:0051960 90 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
apical junction assembly GO:0043297 1 0.013
cellular biosynthetic process GO:0044249 286 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
cellular localization GO:0051641 97 0.013
cellular biogenic amine metabolic process GO:0006576 2 0.013
branching morphogenesis of a nerve GO:0048755 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
central nervous system development GO:0007417 387 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
primary alcohol metabolic process GO:0034308 7 0.012
cell projection assembly GO:0030031 64 0.012
gene expression GO:0010467 252 0.012
lateral inhibition GO:0046331 1 0.012
phagocytosis GO:0006909 3 0.012
cellular response to fatty acid GO:0071398 3 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
cellular hormone metabolic process GO:0034754 19 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cellular response to organic substance GO:0071310 105 0.012
stem cell maintenance GO:0019827 4 0.012
urea transport GO:0015840 11 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
Zebrafish
protein localization to plasma membrane GO:0072659 1 0.011
muscle organ development GO:0007517 101 0.011
blood coagulation fibrin clot formation GO:0072378 3 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of cell death GO:0010941 103 0.011
small molecule catabolic process GO:0044282 3 0.011
oxoacid metabolic process GO:0043436 31 0.011
photoreceptor cell fate specification GO:0043704 1 0.011
spermatid differentiation GO:0048515 2 0.011
gas transport GO:0015669 3 0.011
programmed cell death GO:0012501 119 0.011
germ cell development GO:0007281 22 0.011
small molecule metabolic process GO:0044281 77 0.011
stem cell differentiation GO:0048863 117 0.011
response to decreased oxygen levels GO:0036293 25 0.011
Zebrafish
negative regulation of cytoplasmic transport GO:1903650 2 0.011
mitochondrion morphogenesis GO:0070584 2 0.011
regulation of metabolic process GO:0019222 359 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
cellular response to lipid GO:0071396 39 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
negative regulation of dna replication GO:0008156 2 0.011
response to stress GO:0006950 263 0.010
Zebrafish
catechol containing compound biosynthetic process GO:0009713 2 0.010
regulation of sodium ion transport GO:0002028 2 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
organic acid metabolic process GO:0006082 31 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
lipid metabolic process GO:0006629 52 0.010

igfbp2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.066
immune system disease DOID:2914 0 0.038
disease of anatomical entity DOID:7 0 0.038
hematopoietic system disease DOID:74 0 0.038
inherited metabolic disorder DOID:655 0 0.034
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
dysostosis DOID:1934 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020