Danio rerio

81 known processes

igfbp3

insulin-like growth factor binding protein 3

(Aliases: zgc:91788,MGC91788,IGFBP-3)

igfbp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ear development GO:0043583 127 0.968
otolith development GO:0048840 32 0.921
developmental growth GO:0048589 166 0.908
Zebrafish
inner ear development GO:0048839 126 0.882
neuroblast proliferation GO:0007405 2 0.839
regulation of developmental process GO:0050793 247 0.834
Human Zebrafish
blood vessel morphogenesis GO:0048514 216 0.795
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.776
regulation of multicellular organismal development GO:2000026 223 0.774
Human
sensory organ development GO:0007423 393 0.739
cation transport GO:0006812 81 0.728
regulation of axonogenesis GO:0050770 32 0.724
inner ear morphogenesis GO:0042472 63 0.721
ion transport GO:0006811 114 0.711
regulation of cell growth GO:0001558 29 0.683
Mouse
cell fate commitment GO:0045165 99 0.663
otic vesicle morphogenesis GO:0071600 34 0.636
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.633
vasculature development GO:0001944 278 0.628
Zebrafish
regulation of axon extension GO:0030516 24 0.599
cell part morphogenesis GO:0032990 246 0.591
embryonic organ development GO:0048568 381 0.542
ear morphogenesis GO:0042471 64 0.533
digestive tract development GO:0048565 265 0.521
neuron projection guidance GO:0097485 86 0.519
regulation of biological quality GO:0065008 263 0.514
otic vesicle formation GO:0030916 27 0.507
growth GO:0040007 174 0.493
Zebrafish Mouse
cell motility GO:0048870 244 0.485
Human
sensory perception of mechanical stimulus GO:0050954 16 0.478
gene expression GO:0010467 252 0.474
positive regulation of muscle organ development GO:0048636 1 0.471
cellular component movement GO:0006928 335 0.453
Human
digestive tract morphogenesis GO:0048546 231 0.451
stem cell proliferation GO:0072089 4 0.439
response to external stimulus GO:0009605 264 0.424
regulation of cellular component size GO:0032535 30 0.422
blood vessel development GO:0001568 246 0.412
Zebrafish
central nervous system development GO:0007417 387 0.406
neuron differentiation GO:0030182 353 0.403
regulation of anatomical structure morphogenesis GO:0022603 130 0.399
semicircular canal development GO:0060872 24 0.395
cell growth GO:0016049 57 0.391
Mouse
response to abiotic stimulus GO:0009628 122 0.370
Zebrafish
protein metabolic process GO:0019538 183 0.369
Human
otic vesicle development GO:0071599 42 0.368
tube morphogenesis GO:0035239 349 0.367
heart morphogenesis GO:0003007 156 0.366
mesoderm development GO:0007498 88 0.360
homeostasis of number of cells GO:0048872 62 0.355
localization of cell GO:0051674 244 0.354
Human
positive regulation of apoptotic process GO:0043065 29 0.345
Human
gland development GO:0048732 143 0.338
developmental growth involved in morphogenesis GO:0060560 86 0.336
regulation of cellular component organization GO:0051128 86 0.322
Mouse
mechanoreceptor differentiation GO:0042490 37 0.320
cilium morphogenesis GO:0060271 85 0.317
stem cell division GO:0017145 1 0.302
axon guidance GO:0007411 86 0.302
regulation of metal ion transport GO:0010959 4 0.300
gastrulation GO:0007369 208 0.299
regulation of cell size GO:0008361 29 0.298
connective tissue development GO:0061448 99 0.294
cell projection morphogenesis GO:0048858 244 0.285
myeloid cell differentiation GO:0030099 86 0.281
biosynthetic process GO:0009058 294 0.272
Zebrafish
negative regulation of axon guidance GO:1902668 1 0.271
chemotaxis GO:0006935 104 0.266
positive regulation of gene expression GO:0010628 71 0.266
regulation of growth GO:0040008 42 0.264
Zebrafish Mouse
response to chemical GO:0042221 320 0.263
regulation of neuron projection development GO:0010975 40 0.261
negative regulation of cellular process GO:0048523 283 0.258
eye development GO:0001654 277 0.258
renal tubule morphogenesis GO:0061333 1 0.254
synaptic growth at neuromuscular junction GO:0051124 2 0.254
locomotion GO:0040011 313 0.254
Human
renal system development GO:0072001 94 0.253
positive regulation of striated muscle tissue development GO:0045844 1 0.252
metal ion transport GO:0030001 58 0.251
response to biotic stimulus GO:0009607 97 0.247
optic placode formation involved in camera type eye formation GO:0046619 3 0.241
negative regulation of growth GO:0045926 10 0.234
Zebrafish
urogenital system development GO:0001655 97 0.233
generation of neurons GO:0048699 385 0.232
larval development GO:0002164 2 0.230
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.228
cellular component morphogenesis GO:0032989 336 0.227
cell migration GO:0016477 237 0.226
Human
head development GO:0060322 303 0.225
lamellipodium assembly GO:0030032 1 0.223
outflow tract morphogenesis GO:0003151 1 0.223
negative regulation of axonogenesis GO:0050771 7 0.216
nephron epithelium morphogenesis GO:0072088 1 0.214
cell migration involved in heart development GO:0060973 22 0.213
axon extension GO:0048675 45 0.212
nephron tubule morphogenesis GO:0072078 1 0.210
regulation of multicellular organismal process GO:0051239 277 0.208
Human Zebrafish
mesoderm morphogenesis GO:0048332 51 0.204
organic substance biosynthetic process GO:1901576 289 0.204
Zebrafish
single organism biosynthetic process GO:0044711 71 0.202
meiotic nuclear division GO:0007126 4 0.200
branching morphogenesis of an epithelial tube GO:0048754 15 0.199
digestive system development GO:0055123 289 0.197
cell proliferation GO:0008283 80 0.197
Human Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.194
cell morphogenesis involved in differentiation GO:0000904 195 0.193
neuron projection morphogenesis GO:0048812 161 0.192
regulation of cell morphogenesis GO:0022604 42 0.192
system process GO:0003008 185 0.190
otic placode formation GO:0043049 23 0.188
regulation of cell differentiation GO:0045595 142 0.181
Human
neural precursor cell proliferation GO:0061351 20 0.179
synapse assembly GO:0007416 9 0.176
taxis GO:0042330 109 0.176
response to other organism GO:0051707 97 0.174
brain development GO:0007420 293 0.173
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.173
regulation of anatomical structure size GO:0090066 33 0.170
artery development GO:0060840 22 0.168
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.168
regulation of primary metabolic process GO:0080090 311 0.164
segmentation GO:0035282 97 0.164
cell projection organization GO:0030030 284 0.161
microtubule cytoskeleton organization GO:0000226 33 0.161
macromolecular complex subunit organization GO:0043933 74 0.158
olfactory lobe development GO:0021988 4 0.155
hemopoiesis GO:0030097 183 0.151
cartilage development GO:0051216 96 0.151
limb bud formation GO:0060174 2 0.151
positive regulation of muscle tissue development GO:1901863 1 0.151
regulation of sodium ion transport GO:0002028 2 0.148
gamete generation GO:0007276 33 0.148
cell migration involved in gastrulation GO:0042074 79 0.146
axonogenesis GO:0007409 152 0.145
negative regulation of multicellular organismal process GO:0051241 69 0.143
Zebrafish
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.143
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.142
signal transduction GO:0007165 455 0.141
female sex differentiation GO:0046660 4 0.141
optic placode formation GO:0001743 4 0.140
regulation of synapse organization GO:0050807 3 0.139
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.137
septum transversum development GO:0003343 4 0.137
angiogenesis GO:0001525 158 0.132
Zebrafish
organ formation GO:0048645 17 0.131
regulation of cell proliferation GO:0042127 37 0.130
Human Zebrafish
transport GO:0006810 220 0.130
cell migration involved in heart formation GO:0060974 10 0.129
regulation of gene expression GO:0010468 265 0.129
regulation of wnt signaling pathway GO:0030111 53 0.127
negative regulation of axon extension GO:0030517 7 0.126
kidney development GO:0001822 92 0.126
regionalization GO:0003002 274 0.126
cell morphogenesis GO:0000902 289 0.125
nuclear division GO:0000280 23 0.123
hematopoietic or lymphoid organ development GO:0048534 191 0.123
extrinsic apoptotic signaling pathway GO:0097191 3 0.122
skeletal system development GO:0001501 181 0.121
immune system process GO:0002376 241 0.120
notochord development GO:0030903 54 0.119
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.119
response to wounding GO:0009611 116 0.117
negative regulation of chemotaxis GO:0050922 4 0.115
peptidyl serine phosphorylation GO:0018105 1 0.113
regulation of skeletal muscle tissue development GO:0048641 4 0.113
Human
cation transmembrane transport GO:0098655 65 0.112
lateral line development GO:0048882 66 0.110
regulation of extent of cell growth GO:0061387 29 0.110
specification of symmetry GO:0009799 204 0.109
nephron morphogenesis GO:0072028 2 0.109
cell surface receptor signaling pathway GO:0007166 325 0.107
neuron development GO:0048666 262 0.107
inner ear receptor cell differentiation GO:0060113 29 0.105
nephron development GO:0072006 31 0.103
endoderm development GO:0007492 49 0.102
negative regulation of cell growth GO:0030308 7 0.102
pronephros development GO:0048793 69 0.101
regulation of developmental growth GO:0048638 38 0.101
Zebrafish
regulation of cell development GO:0060284 100 0.100
Human
hormone biosynthetic process GO:0042446 3 0.100
negative regulation of heart contraction GO:0045822 2 0.100
immune system development GO:0002520 191 0.100
regulation of signal transduction GO:0009966 225 0.100
negative regulation of neuron projection development GO:0010977 9 0.098
neuron projection extension GO:1990138 45 0.098
endoderm formation GO:0001706 29 0.098
pectoral fin development GO:0033339 50 0.097
response to stress GO:0006950 263 0.097
Zebrafish
negative regulation of developmental process GO:0051093 65 0.097
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.096
morphogenesis of a branching structure GO:0001763 21 0.096
camera type eye development GO:0043010 222 0.094
sensory perception GO:0007600 39 0.094
single organism reproductive process GO:0044702 40 0.093
regulation of cell projection organization GO:0031344 44 0.093
fin development GO:0033333 77 0.092
hair cell differentiation GO:0035315 32 0.092
heterocycle biosynthetic process GO:0018130 215 0.092
axonal defasciculation GO:0007414 2 0.091
cellular nitrogen compound biosynthetic process GO:0044271 218 0.091
positive regulation of cellular component biogenesis GO:0044089 3 0.090
dorsal ventral pattern formation GO:0009953 125 0.089
autophagy GO:0006914 4 0.088
peripheral nervous system development GO:0007422 55 0.088
regulation of synapse assembly GO:0051963 3 0.088
amino acid transport GO:0006865 2 0.087
mesenchymal cell development GO:0014031 78 0.087
single organism organelle organization GO:1902589 199 0.087
regulation of cell projection assembly GO:0060491 4 0.087
positive regulation of transport GO:0051050 2 0.087
developmental cell growth GO:0048588 52 0.086
positive regulation of response to stimulus GO:0048584 80 0.085
Mouse
eye morphogenesis GO:0048592 144 0.084
sodium ion transmembrane transport GO:0035725 21 0.084
monovalent inorganic cation transport GO:0015672 42 0.084
regulation of macromolecule biosynthetic process GO:0010556 225 0.083
sodium ion transport GO:0006814 24 0.083
neurological system process GO:0050877 62 0.083
cell cycle GO:0007049 93 0.083
proepicardium development GO:0003342 4 0.083
neuron projection development GO:0031175 180 0.082
embryonic camera type eye development GO:0031076 29 0.082
regulation of multicellular organism growth GO:0040014 4 0.082
Zebrafish
heart development GO:0007507 313 0.081
Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.081
endodermal cell fate commitment GO:0001711 18 0.080
negative regulation of signal transduction GO:0009968 94 0.080
determination of bilateral symmetry GO:0009855 204 0.080
organelle fission GO:0048285 23 0.080
skin development GO:0043588 54 0.080
positive regulation of secretion GO:0051047 1 0.079
morphogenesis of an epithelium GO:0002009 333 0.079
cranial suture morphogenesis GO:0060363 1 0.078
sprouting angiogenesis GO:0002040 53 0.077
stem cell differentiation GO:0048863 117 0.077
semicircular canal morphogenesis GO:0048752 18 0.077
embryonic eye morphogenesis GO:0048048 30 0.077
regulation of reproductive process GO:2000241 4 0.076
transcription from rna polymerase ii promoter GO:0006366 80 0.076
convergent extension GO:0060026 118 0.076
regulation of epithelial cell proliferation GO:0050678 3 0.075
wnt signaling pathway GO:0016055 80 0.075
morphogenesis of a branching epithelium GO:0061138 16 0.073
negative regulation of growth rate GO:0045967 1 0.073
central nervous system neuron differentiation GO:0021953 74 0.073
ribonucleoside monophosphate catabolic process GO:0009158 4 0.073
negative regulation of striated muscle tissue development GO:0045843 2 0.073
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.073
regulation of neuron differentiation GO:0045664 56 0.072
somatic muscle development GO:0007525 4 0.072
positive regulation of cell communication GO:0010647 56 0.071
Mouse
mesoderm formation GO:0001707 43 0.070
sensory system development GO:0048880 76 0.070
g1 s transition of mitotic cell cycle GO:0000082 1 0.069
modulation by virus of host morphology or physiology GO:0019048 1 0.069
positive regulation of neuron death GO:1901216 1 0.068
synapse organization GO:0050808 21 0.068
secondary metabolic process GO:0019748 3 0.068
lamellipodium organization GO:0097581 1 0.068
positive regulation of skeletal muscle tissue development GO:0048643 1 0.067
positive regulation of neuron apoptotic process GO:0043525 1 0.066
regulation of organelle organization GO:0033043 29 0.066
multi organism process GO:0051704 134 0.065
endocardium morphogenesis GO:0003160 4 0.065
locus ceruleus development GO:0021703 3 0.065
formation of anatomical boundary GO:0048859 14 0.064
sensory perception of sound GO:0007605 9 0.064
inorganic cation transmembrane transport GO:0098662 50 0.064
axon development GO:0061564 166 0.064
cell cell adhesion GO:0098609 6 0.064
negative chemotaxis GO:0050919 1 0.064
regulation of mitosis GO:0007088 9 0.064
homeostatic process GO:0042592 142 0.062
cellular biosynthetic process GO:0044249 286 0.062
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.062
positive regulation of programmed cell death GO:0043068 29 0.062
Human
peptidyl serine modification GO:0018209 2 0.061
photoreceptor cell fate specification GO:0043704 1 0.061
regulation of biosynthetic process GO:0009889 250 0.061
cellular response to external stimulus GO:0071496 2 0.061
regulation of chondrocyte differentiation GO:0032330 1 0.060
positive regulation of developmental process GO:0051094 50 0.060
Human
aromatic compound biosynthetic process GO:0019438 217 0.060
canonical wnt signaling pathway GO:0060070 48 0.059
development of primary female sexual characteristics GO:0046545 4 0.059
cellular aromatic compound metabolic process GO:0006725 295 0.058
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.058
nephron epithelium development GO:0072009 16 0.058
nucleobase containing compound metabolic process GO:0006139 274 0.058
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.057
olfactory bulb development GO:0021772 4 0.057
periodic partitioning GO:0007365 1 0.057
diencephalon development GO:0021536 58 0.057
epidermis development GO:0008544 48 0.057
regulation of autophagy GO:0010506 3 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.056
myeloid cell homeostasis GO:0002262 56 0.056
tissue remodeling GO:0048771 4 0.056
negative regulation of biological process GO:0048519 304 0.056
cellular protein metabolic process GO:0044267 129 0.056
Human
neuron migration GO:0001764 22 0.055
regulation of axon extension involved in axon guidance GO:0048841 6 0.055
anterior posterior axon guidance GO:0033564 5 0.055
embryonic heart tube development GO:0035050 133 0.055
regulation of ion transport GO:0043269 22 0.055
positive regulation of map kinase activity GO:0043406 3 0.055
positive regulation of secretion by cell GO:1903532 1 0.055
regulation of rna metabolic process GO:0051252 224 0.054
regulation of protein complex assembly GO:0043254 3 0.054
extracellular matrix organization GO:0030198 27 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.053
nucleoside monophosphate catabolic process GO:0009125 4 0.053
nucleobase containing compound biosynthetic process GO:0034654 205 0.052
positive regulation of transcription dna templated GO:0045893 57 0.052
spinal cord radial glial cell differentiation GO:0021531 2 0.052
rhombomere 6 development GO:0021572 4 0.052
cytoskeleton organization GO:0007010 96 0.052
multicellular organism growth GO:0035264 4 0.052
Zebrafish
endocardial cushion formation GO:0003272 2 0.051
intramembranous ossification GO:0001957 3 0.051
epidermal cell differentiation GO:0009913 36 0.051
cardiac ventricle development GO:0003231 9 0.051
cortical actin cytoskeleton organization GO:0030866 1 0.051
craniofacial suture morphogenesis GO:0097094 2 0.050
aminoglycan metabolic process GO:0006022 9 0.050
mesenchyme development GO:0060485 127 0.050
response to alkaloid GO:0043279 2 0.050
fin morphogenesis GO:0033334 53 0.050
glycosaminoglycan metabolic process GO:0030203 9 0.050
regulation of meiotic cell cycle GO:0051445 1 0.050
multicellular organismal reproductive process GO:0048609 35 0.050
negative regulation of cellular component organization GO:0051129 16 0.049
establishment of mitotic spindle localization GO:0040001 12 0.049
lateral line system development GO:0048925 76 0.049
regulation of cell communication GO:0010646 232 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.049
positive regulation of stress activated mapk cascade GO:0032874 3 0.049
regulation of cell shape GO:0008360 1 0.049
heart formation GO:0060914 13 0.049
rhombomere 5 development GO:0021571 4 0.048
inner ear receptor cell fate commitment GO:0060120 4 0.048
regulation of striated muscle tissue development GO:0016202 6 0.048
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.048
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.048
regulation of cellular biosynthetic process GO:0031326 245 0.047
oocyte maturation GO:0001556 4 0.047
endodermal cell differentiation GO:0035987 19 0.047
fin regeneration GO:0031101 51 0.047
tissue regeneration GO:0042246 74 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.047
positive regulation of cell cycle GO:0045787 3 0.047
regulation of vesicle mediated transport GO:0060627 9 0.046
cellular response to growth factor stimulus GO:0071363 39 0.046
purine nucleoside monophosphate catabolic process GO:0009128 4 0.046
embryonic pattern specification GO:0009880 44 0.046
positive regulation of wnt signaling pathway GO:0030177 13 0.045
epithelial cell differentiation GO:0030855 116 0.045
regulation of metabolic process GO:0019222 359 0.045
chordate embryonic development GO:0043009 271 0.045
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.045
regulation of mapk cascade GO:0043408 14 0.045
Mouse
embryonic camera type eye morphogenesis GO:0048596 19 0.044
embryonic organ morphogenesis GO:0048562 274 0.044
appendage morphogenesis GO:0035107 56 0.044
cell cycle process GO:0022402 53 0.044
determination of heart left right asymmetry GO:0061371 117 0.044
convergent extension involved in gastrulation GO:0060027 71 0.044
cellular component assembly GO:0022607 170 0.043
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.043
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.043
pectoral fin morphogenesis GO:0035138 29 0.043
defense response GO:0006952 47 0.042
positive regulation of multicellular organismal process GO:0051240 52 0.042
glomerulus development GO:0032835 27 0.042
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.042
cell migration to the midline involved in heart development GO:0003318 12 0.041
muscle structure development GO:0061061 196 0.041
Human
formation of primary germ layer GO:0001704 62 0.041
somitogenesis GO:0001756 87 0.041
ovulation cycle process GO:0022602 2 0.041
cell fate specification GO:0001708 68 0.041
appendage development GO:0048736 80 0.041
positive regulation of cell division GO:0051781 2 0.041
nuclear export GO:0051168 1 0.041
maintenance of location GO:0051235 4 0.041
auditory receptor cell fate determination GO:0042668 2 0.040
response to growth factor GO:0070848 39 0.040
circulatory system process GO:0003013 87 0.040
epithelial tube morphogenesis GO:0060562 148 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.040
response to external biotic stimulus GO:0043207 97 0.040
stem cell development GO:0048864 82 0.040
determination of intestine left right asymmetry GO:0071908 2 0.040
rhombomere development GO:0021546 19 0.039
response to hexose GO:0009746 3 0.039
defense response to other organism GO:0098542 33 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.038
angioblast cell migration GO:0035476 9 0.038
regulation of localization GO:0032879 104 0.038
Human
startle response GO:0001964 4 0.038
lens development in camera type eye GO:0002088 22 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
Zebrafish
kidney epithelium development GO:0072073 23 0.038
erythrocyte differentiation GO:0030218 54 0.037
forebrain neuron differentiation GO:0021879 14 0.037
pharyngeal system development GO:0060037 18 0.037
actin filament organization GO:0007015 15 0.037
somite development GO:0061053 96 0.037
neuron recognition GO:0008038 18 0.037
organelle organization GO:0006996 227 0.037
heterocycle metabolic process GO:0046483 290 0.037
Zebrafish
positive regulation of muscle cell differentiation GO:0051149 1 0.037
Human
regulation of cellular response to growth factor stimulus GO:0090287 35 0.036
enzyme linked receptor protein signaling pathway GO:0007167 106 0.036
regeneration GO:0031099 91 0.035
meiosis i GO:0007127 1 0.035
negative regulation of macromolecule metabolic process GO:0010605 76 0.035
Human Zebrafish
cellular component biogenesis GO:0044085 178 0.035
regulation of embryonic development GO:0045995 47 0.035
response to carbohydrate GO:0009743 3 0.035
exocrine system development GO:0035272 28 0.035
embryonic skeletal system morphogenesis GO:0048704 93 0.034
negative regulation of biosynthetic process GO:0009890 55 0.034
Zebrafish
stem cell maintenance GO:0019827 4 0.034
osteoblast differentiation GO:0001649 5 0.034
Mouse
regulation of transcription dna templated GO:0006355 213 0.034
response to axon injury GO:0048678 14 0.034
female gonad development GO:0008585 4 0.033
direct ossification GO:0036072 3 0.033
embryonic appendage morphogenesis GO:0035113 30 0.033
cellular response to organic substance GO:0071310 105 0.033
response to corticosteroid GO:0031960 1 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.032
semicircular canal formation GO:0060876 4 0.032
mitotic cell cycle process GO:1903047 48 0.032
regulation of cardiac muscle cell contraction GO:0086004 1 0.032
spermatid development GO:0007286 2 0.032
reproductive process GO:0022414 40 0.032
vestibular receptor cell differentiation GO:0060114 3 0.032
regulation of response to cytokine stimulus GO:0060759 3 0.032
reproduction GO:0000003 40 0.032
negative regulation of blood circulation GO:1903523 2 0.031
response to endogenous stimulus GO:0009719 83 0.031
retina morphogenesis in camera type eye GO:0060042 79 0.031
regulation of cytoskeleton organization GO:0051493 11 0.031
meiotic cell cycle process GO:1903046 3 0.031
response to bacterium GO:0009617 58 0.031
regulation of signaling GO:0023051 235 0.031
cell death GO:0008219 121 0.031
Human
neuroblast differentiation GO:0014016 1 0.031
endocrine system development GO:0035270 65 0.031
negative regulation of dna replication GO:0008156 2 0.030
Zebrafish
glycosaminoglycan biosynthetic process GO:0006024 8 0.030
negative regulation of cell projection organization GO:0031345 9 0.030
regulation of heart growth GO:0060420 2 0.030
carbohydrate biosynthetic process GO:0016051 1 0.030
behavior GO:0007610 74 0.030
negative regulation of axon regeneration GO:0048681 4 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
Human Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.029
blood circulation GO:0008015 87 0.029
cell cycle g2 m phase transition GO:0044839 4 0.029
rna metabolic process GO:0016070 219 0.029
muscle organ development GO:0007517 101 0.029
Human
positive regulation of biosynthetic process GO:0009891 68 0.029
determination of left right symmetry GO:0007368 179 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
Mouse
actin filament based process GO:0030029 64 0.029
post embryonic organ development GO:0048569 4 0.029
cell cycle g1 s phase transition GO:0044843 1 0.028
death GO:0016265 121 0.028
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
organelle transport along microtubule GO:0072384 1 0.028
response to nutrient GO:0007584 3 0.028
regulation of actin filament based movement GO:1903115 1 0.028
motor neuron axon guidance GO:0008045 23 0.028
programmed cell death GO:0012501 119 0.028
Human
forebrain development GO:0030900 96 0.027
spindle localization GO:0051653 12 0.027
renal tubule development GO:0061326 5 0.027
positive regulation of synapse assembly GO:0051965 1 0.027
heart contraction GO:0060047 71 0.027
cardiogenic plate morphogenesis GO:0003142 1 0.027
liver development GO:0001889 96 0.027
establishment of localization GO:0051234 244 0.027
protein polymerization GO:0051258 4 0.027

igfbp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.298
cardiovascular system disease DOID:1287 0 0.145
musculoskeletal system disease DOID:17 0 0.079
nervous system disease DOID:863 0 0.038
auditory system disease DOID:2742 0 0.036
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.036
nonsyndromic deafness DOID:0050563 0 0.036
sensory system disease DOID:0050155 0 0.036
myopathy DOID:423 0 0.029
muscular disease DOID:0080000 0 0.029
muscle tissue disease DOID:66 0 0.029