Danio rerio

28 known processes

ikzf1

IKAROS family zinc finger 1 (Ikaros)

(Aliases: ikaros,znfn1a1)

ikzf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hematopoietic or lymphoid organ development GO:0048534 191 0.995
immune system development GO:0002520 191 0.988
hemopoiesis GO:0030097 183 0.956
regulation of leukocyte differentiation GO:1902105 5 0.925
Mouse
homeostasis of number of cells GO:0048872 62 0.914
immune system process GO:0002376 241 0.901
regulation of nitrogen compound metabolic process GO:0051171 251 0.871
Mouse
regulation of multicellular organismal process GO:0051239 277 0.848
Mouse
gene expression GO:0010467 252 0.796
Mouse
regulation of neutrophil differentiation GO:0045658 3 0.785
Mouse
regulation of primary metabolic process GO:0080090 311 0.755
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.751
Mouse
epithelial cell differentiation GO:0030855 116 0.744
negative regulation of biological process GO:0048519 304 0.739
Mouse
lymphocyte differentiation GO:0030098 9 0.719
heterocycle metabolic process GO:0046483 290 0.704
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.646
Mouse
gland development GO:0048732 143 0.620
Mouse
actin filament based process GO:0030029 64 0.608
embryonic hemopoiesis GO:0035162 53 0.601
erythrocyte differentiation GO:0030218 54 0.600
macromolecular complex subunit organization GO:0043933 74 0.591
organic cyclic compound biosynthetic process GO:1901362 223 0.589
Mouse
negative regulation of developmental process GO:0051093 65 0.567
tissue remodeling GO:0048771 4 0.561
histone h3 k4 methylation GO:0051568 2 0.559
erythrocyte homeostasis GO:0034101 55 0.549
leukocyte differentiation GO:0002521 25 0.535
negative regulation of macromolecule metabolic process GO:0010605 76 0.526
Mouse
regulation of metabolic process GO:0019222 359 0.525
Mouse
regulation of multicellular organismal development GO:2000026 223 0.490
Mouse
regulation of cellular metabolic process GO:0031323 320 0.488
Mouse
eye development GO:0001654 277 0.486
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.480
positive regulation of cellular metabolic process GO:0031325 94 0.467
Mouse
macromolecule biosynthetic process GO:0009059 227 0.459
Mouse
nitrogen compound metabolic process GO:0006807 319 0.449
Mouse
hematopoietic stem cell migration GO:0035701 4 0.438
regulation of macromolecule metabolic process GO:0060255 317 0.437
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.431
Mouse
regulation of developmental process GO:0050793 247 0.425
Mouse
cell migration GO:0016477 237 0.424
cellular ketone metabolic process GO:0042180 11 0.420
negative regulation of multicellular organismal process GO:0051241 69 0.413
transcription dna templated GO:0006351 181 0.410
Mouse
chromosome organization GO:0051276 31 0.406
cellular macromolecule biosynthetic process GO:0034645 224 0.403
Mouse
positive regulation of cell activation GO:0050867 1 0.393
Mouse
myeloid leukocyte differentiation GO:0002573 15 0.390
Mouse
lymphocyte activation GO:0046649 10 0.386
regulation of cell differentiation GO:0045595 142 0.384
Mouse
heterocycle biosynthetic process GO:0018130 215 0.384
Mouse
myeloid cell differentiation GO:0030099 86 0.378
Mouse
striated muscle tissue development GO:0014706 110 0.376
definitive hemopoiesis GO:0060216 18 0.373
angiogenesis GO:0001525 158 0.369
cellular nitrogen compound metabolic process GO:0034641 290 0.358
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.358
Mouse
leukocyte homeostasis GO:0001776 2 0.349
rna metabolic process GO:0016070 219 0.345
Mouse
positive regulation of biological process GO:0048518 253 0.319
Mouse
amine metabolic process GO:0009308 2 0.315
protein complex subunit organization GO:0071822 46 0.305
blood vessel development GO:0001568 246 0.304
regulation of erythrocyte differentiation GO:0045646 2 0.302
death GO:0016265 121 0.293
locomotion GO:0040011 313 0.289
cellular protein metabolic process GO:0044267 129 0.288
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.287
heart development GO:0007507 313 0.286
embryonic organ development GO:0048568 381 0.286
regulation of rna biosynthetic process GO:2001141 213 0.285
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.283
Mouse
biosynthetic process GO:0009058 294 0.276
Mouse
cellular component morphogenesis GO:0032989 336 0.267
cell morphogenesis GO:0000902 289 0.259
regulation of nucleic acid templated transcription GO:1903506 213 0.258
Mouse
establishment of localization in cell GO:0051649 77 0.256
response to biotic stimulus GO:0009607 97 0.255
negative regulation of gene expression GO:0010629 65 0.255
Mouse
erythrocyte maturation GO:0043249 8 0.250
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.249
embryonic heart tube development GO:0035050 133 0.249
cellular component assembly GO:0022607 170 0.246
tube morphogenesis GO:0035239 349 0.243
ventricular cardiac muscle cell development GO:0055015 5 0.240
digestive system development GO:0055123 289 0.231
t cell differentiation in thymus GO:0033077 6 0.230
regulation of cellular component organization GO:0051128 86 0.228
cellular response to endogenous stimulus GO:0071495 68 0.226
negative regulation of biosynthetic process GO:0009890 55 0.225
Mouse
thymus development GO:0048538 10 0.224
Mouse
vasculature development GO:0001944 278 0.223
cell death GO:0008219 121 0.221
cell morphogenesis involved in differentiation GO:0000904 195 0.219
positive regulation of cytokine production GO:0001819 2 0.218
axonal defasciculation GO:0007414 2 0.218
cell projection organization GO:0030030 284 0.218
negative regulation of cellular process GO:0048523 283 0.216
Mouse
phagocytosis GO:0006909 3 0.214
erythrocyte development GO:0048821 24 0.213
response to chemical GO:0042221 320 0.210
stem cell proliferation GO:0072089 4 0.207
regulation of apoptotic process GO:0042981 98 0.206
regulation of biological quality GO:0065008 263 0.206
cellular amine metabolic process GO:0044106 2 0.203
organic substance biosynthetic process GO:1901576 289 0.201
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.195
Mouse
regulation of biosynthetic process GO:0009889 250 0.191
Mouse
myeloid cell homeostasis GO:0002262 56 0.187
regulation of cell activation GO:0050865 1 0.185
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.184
multicellular organismal metabolic process GO:0044236 2 0.184
chemotaxis GO:0006935 104 0.184
negative regulation of cellular biosynthetic process GO:0031327 55 0.184
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.183
axon guidance GO:0007411 86 0.179
lens fiber cell development GO:0070307 3 0.177
regulation of response to stimulus GO:0048583 269 0.177
negative regulation of protein phosphorylation GO:0001933 4 0.177
regulation of cell death GO:0010941 103 0.173
rna biosynthetic process GO:0032774 181 0.173
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.172
Mouse
regulation of gene expression GO:0010468 265 0.168
Mouse
homeostatic process GO:0042592 142 0.163
regulation of stem cell proliferation GO:0072091 2 0.162
central nervous system development GO:0007417 387 0.160
Mouse
digestive tract development GO:0048565 265 0.155
regulation of histone methylation GO:0031060 3 0.155
regulation of programmed cell death GO:0043067 101 0.154
positive regulation of apoptotic signaling pathway GO:2001235 1 0.153
cellular component movement GO:0006928 335 0.152
camera type eye development GO:0043010 222 0.151
Mouse
nuclear transport GO:0051169 4 0.151
digestive tract morphogenesis GO:0048546 231 0.149
defense response GO:0006952 47 0.149
regulation of cytokine production GO:0001817 3 0.147
positive regulation of biosynthetic process GO:0009891 68 0.146
Mouse
apoptotic process GO:0006915 116 0.137
macromolecular complex assembly GO:0065003 35 0.137
response to bacterium GO:0009617 58 0.137
generation of neurons GO:0048699 385 0.135
primitive erythrocyte differentiation GO:0060319 5 0.135
cellular nitrogen compound biosynthetic process GO:0044271 218 0.134
Mouse
neuron development GO:0048666 262 0.133
muscle structure development GO:0061061 196 0.132
organonitrogen compound metabolic process GO:1901564 74 0.132
neuron differentiation GO:0030182 353 0.131
negative regulation of metabolic process GO:0009892 86 0.130
Mouse
cell motility GO:0048870 244 0.129
regulation of establishment of protein localization GO:0070201 4 0.127
regulation of anatomical structure morphogenesis GO:0022603 130 0.127
regulation of cellular biosynthetic process GO:0031326 245 0.126
Mouse
positive regulation of cell death GO:0010942 29 0.125
cell surface receptor signaling pathway GO:0007166 325 0.124
mesenchymal cell differentiation GO:0048762 87 0.123
positive regulation of developmental process GO:0051094 50 0.122
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.121
Mouse
nucleocytoplasmic transport GO:0006913 4 0.121
positive regulation of locomotion GO:0040017 14 0.119
sprouting angiogenesis GO:0002040 53 0.119
leukocyte activation GO:0045321 12 0.116
carboxylic acid metabolic process GO:0019752 22 0.114
granulocyte differentiation GO:0030851 8 0.111
Mouse
cytokinesis GO:0000910 3 0.110
localization of cell GO:0051674 244 0.110
cell projection morphogenesis GO:0048858 244 0.110
small molecule metabolic process GO:0044281 77 0.109
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.109
gastrulation GO:0007369 208 0.108
cytoskeleton organization GO:0007010 96 0.107
regulation of epithelial cell proliferation GO:0050678 3 0.105
dorsal aorta morphogenesis GO:0035912 3 0.105
regulation of cell shape GO:0008360 1 0.104
regulation of translational initiation GO:0006446 1 0.104
response to organic substance GO:0010033 153 0.104
oxoacid metabolic process GO:0043436 31 0.103
cellular biosynthetic process GO:0044249 286 0.103
Mouse
stem cell differentiation GO:0048863 117 0.101
single organismal cell cell adhesion GO:0016337 29 0.101
protein modification process GO:0036211 100 0.100
nucleic acid metabolic process GO:0090304 244 0.100
Mouse
regulation of homeostatic process GO:0032844 9 0.100
lymphatic endothelial cell differentiation GO:0060836 1 0.098
aromatic compound biosynthetic process GO:0019438 217 0.098
Mouse
actin cytoskeleton organization GO:0030036 63 0.097
cell division GO:0051301 20 0.094
liver development GO:0001889 96 0.094
cellular component biogenesis GO:0044085 178 0.093
regulation of signaling GO:0023051 235 0.092
primitive hemopoiesis GO:0060215 27 0.092
larval development GO:0002164 2 0.091
regulation of immune system process GO:0002682 34 0.090
Mouse
response to amino acid GO:0043200 2 0.089
neuroblast proliferation GO:0007405 2 0.087
regulation of cellular amine metabolic process GO:0033238 0 0.085
brain development GO:0007420 293 0.084
Mouse
macromolecule modification GO:0043412 111 0.084
response to oxygen containing compound GO:1901700 55 0.083
t cell differentiation GO:0030217 6 0.082
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.082
Mouse
response to external stimulus GO:0009605 264 0.082
regulation of cell adhesion GO:0030155 15 0.081
heart looping GO:0001947 94 0.081
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.080
Mouse
negative regulation of rna metabolic process GO:0051253 48 0.080
Mouse
response to other organism GO:0051707 97 0.080
organelle organization GO:0006996 227 0.079
negative regulation of nucleic acid templated transcription GO:1903507 45 0.079
Mouse
cellular response to oxygen radical GO:0071450 2 0.078
morphogenesis of an epithelium GO:0002009 333 0.078
axon development GO:0061564 166 0.076
maintenance of location GO:0051235 4 0.076
apoptotic process involved in development GO:1902742 2 0.075
embryonic heart tube morphogenesis GO:0003143 108 0.075
determination of left right symmetry GO:0007368 179 0.074
negative regulation of rna biosynthetic process GO:1902679 45 0.073
Mouse
lymph vessel development GO:0001945 27 0.073
removal of superoxide radicals GO:0019430 2 0.073
cellular localization GO:0051641 97 0.072
regulation of protein phosphorylation GO:0001932 18 0.072
regulation of localization GO:0032879 104 0.072
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.071
signal transduction GO:0007165 455 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.070
Mouse
lymphocyte homeostasis GO:0002260 1 0.069
positive regulation of transport GO:0051050 2 0.068
regulation of cell motility GO:2000145 46 0.068
protein metabolic process GO:0019538 183 0.067
auditory receptor cell fate determination GO:0042668 2 0.067
negative regulation of cell differentiation GO:0045596 46 0.066
single organism organelle organization GO:1902589 199 0.066
neurotransmitter secretion GO:0007269 2 0.066
cell activation GO:0001775 16 0.066
stem cell development GO:0048864 82 0.064
endocrine system development GO:0035270 65 0.064
positive regulation of macromolecule metabolic process GO:0010604 93 0.061
Mouse
positive regulation of neuron migration GO:2001224 2 0.061
programmed cell death GO:0012501 119 0.060
superoxide metabolic process GO:0006801 2 0.060
cellular amino acid metabolic process GO:0006520 7 0.059
mechanoreceptor differentiation GO:0042490 37 0.059
sensory organ development GO:0007423 393 0.059
Mouse
dna alkylation GO:0006305 8 0.058
regulation of cellular ketone metabolic process GO:0010565 7 0.058
intracellular estrogen receptor signaling pathway GO:0030520 3 0.058
cellular response to cytokine stimulus GO:0071345 7 0.058
regulation of rna metabolic process GO:0051252 224 0.057
Mouse
positive regulation of cellular process GO:0048522 201 0.057
Mouse
production of molecular mediator of immune response GO:0002440 2 0.057
blood vessel morphogenesis GO:0048514 216 0.057
sensory perception of chemical stimulus GO:0007606 3 0.056
positive regulation of secretion by cell GO:1903532 1 0.056
positive regulation of map kinase activity GO:0043406 3 0.055
antimicrobial humoral response GO:0019730 2 0.055
protein complex assembly GO:0006461 30 0.054
regulation of molecular function GO:0065009 70 0.054
regulation of transcription dna templated GO:0006355 213 0.054
Mouse
cell substrate adhesion GO:0031589 4 0.054
auditory receptor cell fate commitment GO:0009912 4 0.053
regulation of dendrite development GO:0050773 3 0.053
positive regulation of apoptotic process GO:0043065 29 0.053
negative regulation of programmed cell death GO:0043069 58 0.053
positive regulation of immune response GO:0050778 11 0.053
positive regulation of signal transduction GO:0009967 56 0.053
regulation of organelle organization GO:0033043 29 0.052
negative regulation of apoptotic process GO:0043066 55 0.051
regulation of catalytic activity GO:0050790 55 0.051
fin morphogenesis GO:0033334 53 0.051
negative regulation of cellular metabolic process GO:0031324 77 0.051
Mouse
regulation of actin cytoskeleton organization GO:0032956 8 0.050
positive regulation of endothelial cell proliferation GO:0001938 1 0.050
blood circulation GO:0008015 87 0.050
g2 m transition of mitotic cell cycle GO:0000086 4 0.050
regulation of cellular protein metabolic process GO:0032268 52 0.050
positive regulation of signaling GO:0023056 56 0.050
transport GO:0006810 220 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.050
Mouse
spindle assembly GO:0051225 2 0.049
collagen metabolic process GO:0032963 2 0.049
organelle assembly GO:0070925 110 0.049
anatomical structure homeostasis GO:0060249 36 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.048
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.048
regulation of endopeptidase activity GO:0052548 23 0.047
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.046
positive regulation of stem cell proliferation GO:2000648 1 0.046
heart morphogenesis GO:0003007 156 0.046
cell fate commitment GO:0045165 99 0.045
negative regulation of cell death GO:0060548 60 0.044
cellular response to chemical stimulus GO:0070887 157 0.044
negative regulation of histone modification GO:0031057 1 0.044
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.044
regulation of cell morphogenesis GO:0022604 42 0.044
cell cycle g2 m phase transition GO:0044839 4 0.043
post embryonic foregut morphogenesis GO:0048618 3 0.043
protein complex biogenesis GO:0070271 30 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.043
inositol lipid mediated signaling GO:0048017 2 0.042
transcription from rna polymerase ii promoter GO:0006366 80 0.042
Mouse
embryonic heart tube formation GO:0003144 1 0.042
immune response regulating signaling pathway GO:0002764 5 0.042
intracellular signal transduction GO:0035556 85 0.042
cellular amide metabolic process GO:0043603 4 0.041
positive regulation of immune effector process GO:0002699 3 0.041
modification dependent macromolecule catabolic process GO:0043632 3 0.041
regulation of neurotransmitter secretion GO:0046928 1 0.041
biological adhesion GO:0022610 40 0.041
neuron projection guidance GO:0097485 86 0.041
proepicardium development GO:0003342 4 0.041
negative regulation of response to stimulus GO:0048585 104 0.041
positive regulation of secretion GO:0051047 1 0.041
regulation of ectoderm development GO:2000383 2 0.041
cellular protein modification process GO:0006464 100 0.040
cell proliferation GO:0008283 80 0.040
eye morphogenesis GO:0048592 144 0.040
cardiogenic plate morphogenesis GO:0003142 1 0.040
regulation of hydrogen peroxide metabolic process GO:0010310 1 0.040
positive regulation of jak stat cascade GO:0046427 2 0.039
vasculogenesis GO:0001570 41 0.039
regulation of wound healing GO:0061041 2 0.039
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.038
leukocyte proliferation GO:0070661 1 0.038
taxis GO:0042330 109 0.038
neuron projection development GO:0031175 180 0.038
regulation of signal transduction GO:0009966 225 0.038
protein secretion GO:0009306 1 0.038
regulation of inflammatory response GO:0050727 2 0.038
behavior GO:0007610 74 0.038
organelle localization GO:0051640 49 0.037
defense response to fungus GO:0050832 2 0.037
retina development in camera type eye GO:0060041 146 0.037
Mouse
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.036
positive regulation of endopeptidase activity GO:0010950 10 0.036
skeletal muscle tissue development GO:0007519 67 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.036
Mouse
response to oxidative stress GO:0006979 11 0.036
positive regulation of cell differentiation GO:0045597 30 0.036
Mouse
positive regulation of metabolic process GO:0009893 108 0.036
Mouse
cell part morphogenesis GO:0032990 246 0.036
regulation of histone h3 k9 methylation GO:0051570 2 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
Mouse
single organism metabolic process GO:0044710 217 0.035
motor neuron axon guidance GO:0008045 23 0.035
regulation of cysteine type endopeptidase activity GO:2000116 21 0.035
positive regulation of response to wounding GO:1903036 5 0.035
muscle tissue development GO:0060537 110 0.034
lymph vessel morphogenesis GO:0036303 25 0.034
internal protein amino acid acetylation GO:0006475 2 0.034
cytosolic calcium ion transport GO:0060401 3 0.034
nucleic acid templated transcription GO:0097659 181 0.034
Mouse
response to retinoic acid GO:0032526 6 0.034
cellular component assembly involved in morphogenesis GO:0010927 107 0.034
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.033
zymogen activation GO:0031638 3 0.033
regulation of response to cytokine stimulus GO:0060759 3 0.033
regulation of cytoskeleton organization GO:0051493 11 0.033
regulation of tissue remodeling GO:0034103 2 0.033
peptidyl tyrosine modification GO:0018212 5 0.032
regulation of locomotion GO:0040012 55 0.032
system process GO:0003008 185 0.032
epithelial cell morphogenesis GO:0003382 2 0.032
tissue homeostasis GO:0001894 25 0.032
response to stress GO:0006950 263 0.031
regulation of protein targeting GO:1903533 2 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
b cell activation GO:0042113 2 0.031
histone h3 k9 methylation GO:0051567 5 0.031
positive regulation of endothelial cell differentiation GO:0045603 2 0.031
appendage development GO:0048736 80 0.031
cellular protein catabolic process GO:0044257 4 0.031
determination of intestine left right asymmetry GO:0071908 2 0.030
regulation of protein complex assembly GO:0043254 3 0.030
mitotic cell cycle process GO:1903047 48 0.030
positive regulation of molecular function GO:0044093 33 0.030
protein import GO:0017038 3 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.029
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.029
single organism membrane organization GO:0044802 20 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
developmental programmed cell death GO:0010623 4 0.029
heart valve formation GO:0003188 4 0.029
myeloid cell development GO:0061515 32 0.028
cardiac atrium morphogenesis GO:0003209 2 0.028
peptide metabolic process GO:0006518 1 0.028
positive regulation of catabolic process GO:0009896 4 0.028
fin development GO:0033333 77 0.028
chordate embryonic development GO:0043009 271 0.028
positive regulation of epithelial cell proliferation GO:0050679 1 0.028
response to hydrogen peroxide GO:0042542 3 0.028
mitotic cell cycle GO:0000278 64 0.028
aging GO:0007568 2 0.027
response to wounding GO:0009611 116 0.027
astrocyte differentiation GO:0048708 1 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
neuron projection morphogenesis GO:0048812 161 0.027
defense response to other organism GO:0098542 33 0.027
protein localization GO:0008104 40 0.027
establishment of localization GO:0051234 244 0.027
epidermal cell differentiation GO:0009913 36 0.027
epithelial cell development GO:0002064 42 0.027
muscle cell differentiation GO:0042692 139 0.027
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.027
regulation of cell cycle g2 m phase transition GO:1902749 4 0.027
regulation of biomineral tissue development GO:0070167 2 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
organic acid metabolic process GO:0006082 31 0.026
establishment of organelle localization GO:0051656 45 0.026
regulation of mononuclear cell migration GO:0071675 1 0.026
myotube differentiation GO:0014902 45 0.026
g1 s transition of mitotic cell cycle GO:0000082 1 0.026
mesenchymal cell proliferation GO:0010463 1 0.026
organelle fusion GO:0048284 3 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
regulation of endothelial cell proliferation GO:0001936 1 0.026
regulation of dna methylation GO:0044030 5 0.026
spindle assembly involved in mitosis GO:0090307 1 0.026
positive regulation of cell cycle GO:0045787 3 0.026
nuclear import GO:0051170 3 0.026
regulation of retina development in camera type eye GO:1902866 2 0.026
negative regulation of erythrocyte differentiation GO:0045647 1 0.026
positive regulation of leukocyte differentiation GO:1902107 1 0.025
Mouse
positive regulation of hydrolase activity GO:0051345 13 0.025
single organism cell adhesion GO:0098602 29 0.025
epithelial cell proliferation GO:0050673 17 0.025
phosphorylation GO:0016310 69 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
regulation of peptidase activity GO:0052547 23 0.025
somatic stem cell maintenance GO:0035019 1 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
regulation of mesenchymal cell proliferation GO:0010464 1 0.024
regulation of sequestering of calcium ion GO:0051282 4 0.024
cellular response to reactive oxygen species GO:0034614 2 0.024
leukocyte migration GO:0050900 15 0.024
mononuclear cell proliferation GO:0032943 1 0.024
negative regulation of transcription dna templated GO:0045892 45 0.024
Mouse
regulation of production of molecular mediator of immune response GO:0002700 1 0.024
cell migration to the midline involved in heart development GO:0003318 12 0.024
regulation of cellular component biogenesis GO:0044087 12 0.024
muscle cell development GO:0055001 115 0.024
axonogenesis GO:0007409 152 0.024
response to cytokine GO:0034097 7 0.024
regulation of protein modification process GO:0031399 29 0.024
regulation of neurogenesis GO:0050767 87 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
monocyte differentiation GO:0030224 2 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
muscle organ development GO:0007517 101 0.023
osteoclast development GO:0036035 1 0.023
regulation of myotube differentiation GO:0010830 2 0.023
homeostasis of number of cells within a tissue GO:0048873 4 0.023
proteolysis GO:0006508 38 0.023
stem cell division GO:0017145 1 0.023
negative regulation of epithelial cell migration GO:0010633 1 0.023
lymphatic endothelial cell fate commitment GO:0060838 1 0.023
neuron migration GO:0001764 22 0.023
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.022
negative regulation of signal transduction GO:0009968 94 0.022
regulation of calcium ion transport GO:0051924 2 0.022
regulation of immune response GO:0050776 14 0.022
atrioventricular valve formation GO:0003190 3 0.022
dna metabolic process GO:0006259 27 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.022
Mouse
negative regulation of leukocyte differentiation GO:1902106 1 0.022
cognition GO:0050890 1 0.022
skeletal system development GO:0001501 181 0.022
negative regulation of mesodermal cell fate specification GO:0042662 3 0.022
response to external biotic stimulus GO:0043207 97 0.022
regulation of protein transport GO:0051223 3 0.022
non canonical wnt signaling pathway GO:0035567 13 0.022
endothelial cell proliferation GO:0001935 11 0.022
regulation of proteolysis GO:0030162 24 0.022
regulation of cellular component movement GO:0051270 55 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.021
negative regulation of cellular component organization GO:0051129 16 0.021
reactive oxygen species metabolic process GO:0072593 6 0.021
embryonic pattern specification GO:0009880 44 0.021
foregut morphogenesis GO:0007440 4 0.021
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
positive regulation of macrophage chemotaxis GO:0010759 1 0.021
granulocyte migration GO:0097530 11 0.021
negative regulation of cytokine production GO:0001818 1 0.021
reactive oxygen species biosynthetic process GO:1903409 1 0.021
phosphorus metabolic process GO:0006793 109 0.021
positive regulation of catalytic activity GO:0043085 25 0.021
t cell activation GO:0042110 6 0.020
formation of primary germ layer GO:0001704 62 0.020
dicarboxylic acid transport GO:0006835 1 0.020
transcription from rna polymerase iii promoter GO:0006383 1 0.020
dorsal aorta development GO:0035907 4 0.020
regulation of cytokine mediated signaling pathway GO:0001959 3 0.020

ikzf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
cardiovascular system disease DOID:1287 0 0.061
cancer DOID:162 0 0.048
disease of cellular proliferation DOID:14566 0 0.048
organ system cancer DOID:0050686 0 0.030