Danio rerio

26 known processes

ikzf5

IKAROS family zinc finger 5

(Aliases: wu:fb55f09,zgc:92405)

ikzf5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.505
morphogenesis of an epithelium GO:0002009 333 0.493
positive regulation of cellular process GO:0048522 201 0.480
positive regulation of biological process GO:0048518 253 0.463
embryonic organ morphogenesis GO:0048562 274 0.448
digestive tract development GO:0048565 265 0.433
cellular nitrogen compound biosynthetic process GO:0044271 218 0.393
heterocycle biosynthetic process GO:0018130 215 0.375
regulation of synapse organization GO:0050807 3 0.366
nitrogen compound metabolic process GO:0006807 319 0.349
embryonic organ development GO:0048568 381 0.342
developmental growth GO:0048589 166 0.332
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.301
regulation of synapse assembly GO:0051963 3 0.296
synaptic growth at neuromuscular junction GO:0051124 2 0.286
cellular nitrogen compound metabolic process GO:0034641 290 0.286
tube morphogenesis GO:0035239 349 0.285
negative regulation of synapse assembly GO:0051964 2 0.282
sensory organ development GO:0007423 393 0.280
ameboidal type cell migration GO:0001667 143 0.262
regulation of nucleic acid templated transcription GO:1903506 213 0.250
regulation of primary metabolic process GO:0080090 311 0.240
larval development GO:0002164 2 0.230
nucleic acid templated transcription GO:0097659 181 0.191
mitochondrion organization GO:0007005 4 0.179
growth GO:0040007 174 0.176
cell migration GO:0016477 237 0.174
cellular aromatic compound metabolic process GO:0006725 295 0.173
heterocycle metabolic process GO:0046483 290 0.171
gastrulation GO:0007369 208 0.170
hematopoietic or lymphoid organ development GO:0048534 191 0.162
central nervous system development GO:0007417 387 0.160
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.157
heart development GO:0007507 313 0.154
regulation of nitrogen compound metabolic process GO:0051171 251 0.153
cell surface receptor signaling pathway GO:0007166 325 0.148
wnt signaling pathway GO:0016055 80 0.147
aromatic compound biosynthetic process GO:0019438 217 0.141
cellular component movement GO:0006928 335 0.139
regulation of biosynthetic process GO:0009889 250 0.134
regulation of developmental process GO:0050793 247 0.132
regulation of nervous system development GO:0051960 90 0.132
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.124
regulation of transcription dna templated GO:0006355 213 0.123
cell motility GO:0048870 244 0.116
gene expression GO:0010467 252 0.113
cellular component assembly GO:0022607 170 0.113
chemical homeostasis GO:0048878 49 0.112
nucleic acid metabolic process GO:0090304 244 0.108
specification of symmetry GO:0009799 204 0.106
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.105
nucleobase containing compound metabolic process GO:0006139 274 0.103
locomotion GO:0040011 313 0.100
mitochondrial transport GO:0006839 2 0.100
regulation of gene expression GO:0010468 265 0.098
regionalization GO:0003002 274 0.096
organic cyclic compound biosynthetic process GO:1901362 223 0.096
organelle organization GO:0006996 227 0.095
regulation of macromolecule biosynthetic process GO:0010556 225 0.092
embryo development ending in birth or egg hatching GO:0009792 271 0.091
multicellular organismal reproductive process GO:0048609 35 0.089
regulation of rna biosynthetic process GO:2001141 213 0.086
regulation of metabolic process GO:0019222 359 0.085
dicarboxylic acid transport GO:0006835 1 0.085
establishment of protein localization to organelle GO:0072594 4 0.084
negative regulation of cellular process GO:0048523 283 0.081
protein modification process GO:0036211 100 0.079
single organism organelle organization GO:1902589 199 0.077
multicellular organism growth GO:0035264 4 0.077
transcription dna templated GO:0006351 181 0.074
protein targeting to nucleus GO:0044744 3 0.073
blood vessel endothelial cell migration GO:0043534 18 0.073
eye development GO:0001654 277 0.073
neuron differentiation GO:0030182 353 0.072
positive regulation of signaling GO:0023056 56 0.071
single organism metabolic process GO:0044710 217 0.070
regulation of wnt signaling pathway GO:0030111 53 0.070
adult behavior GO:0030534 2 0.068
regulation of multicellular organismal development GO:2000026 223 0.067
phosphorylation GO:0016310 69 0.066
regulation of rna metabolic process GO:0051252 224 0.066
regulation of cellular metabolic process GO:0031323 320 0.064
multi organism process GO:0051704 134 0.063
biosynthetic process GO:0009058 294 0.063
synapse assembly GO:0007416 9 0.062
organic substance biosynthetic process GO:1901576 289 0.062
gland development GO:0048732 143 0.061
localization of cell GO:0051674 244 0.061
cognition GO:0050890 1 0.061
digestive system development GO:0055123 289 0.060
regulation of multicellular organismal process GO:0051239 277 0.059
cation homeostasis GO:0055080 33 0.059
cell aging GO:0007569 2 0.059
epiboly GO:0090504 41 0.058
neuron projection morphogenesis GO:0048812 161 0.058
rna metabolic process GO:0016070 219 0.058
anion transport GO:0006820 38 0.056
cell projection organization GO:0030030 284 0.054
protein import into nucleus GO:0006606 3 0.053
cellular biosynthetic process GO:0044249 286 0.052
regulation of cellular biosynthetic process GO:0031326 245 0.051
cellular macromolecule biosynthetic process GO:0034645 224 0.051
homeostatic process GO:0042592 142 0.051
transcription from rna polymerase ii promoter GO:0006366 80 0.050
cellular protein metabolic process GO:0044267 129 0.050
neuron development GO:0048666 262 0.048
regulation of cellular amine metabolic process GO:0033238 0 0.047
protein metabolic process GO:0019538 183 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.046
skeletal system development GO:0001501 181 0.045
protein localization to nucleus GO:0034504 3 0.045
cellular macromolecule metabolic process GO:0044260 391 0.044
regulation of phosphorus metabolic process GO:0051174 43 0.044
regulation of protein catabolic process GO:0042176 1 0.043
regulation of synapse structure and activity GO:0050803 5 0.043
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.043
response to abiotic stimulus GO:0009628 122 0.043
positive regulation of transport GO:0051050 2 0.043
regulation of synaptic plasticity GO:0048167 1 0.042
camera type eye development GO:0043010 222 0.042
positive regulation of cellular amine metabolic process GO:0033240 0 0.041
regulation of reproductive process GO:2000241 4 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
epithelial tube morphogenesis GO:0060562 148 0.041
oxoacid metabolic process GO:0043436 31 0.040
peptidyl lysine acetylation GO:0018394 2 0.040
cellular response to toxic substance GO:0097237 1 0.040
macromolecule modification GO:0043412 111 0.040
immune system development GO:0002520 191 0.039
single organism nuclear import GO:1902593 3 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
chromosome organization involved in meiosis GO:0070192 1 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.038
nuclear import GO:0051170 3 0.037
cellular ketone metabolic process GO:0042180 11 0.037
regulation of cell aging GO:0090342 1 0.037
phosphate containing compound metabolic process GO:0006796 108 0.037
nucleocytoplasmic transport GO:0006913 4 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.037
amine metabolic process GO:0009308 2 0.037
protein phosphorylation GO:0006468 47 0.036
response to light stimulus GO:0009416 46 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
regulation of jak stat cascade GO:0046425 3 0.036
regulation of cell activation GO:0050865 1 0.035
positive regulation of catabolic process GO:0009896 4 0.034
cellular transition metal ion homeostasis GO:0046916 3 0.034
regulation of cellular component organization GO:0051128 86 0.034
gastrulation with mouth forming second GO:0001702 44 0.034
cellular amine metabolic process GO:0044106 2 0.034
cell projection morphogenesis GO:0048858 244 0.033
regulation of cell migration GO:0030334 40 0.033
regulation of cell morphogenesis GO:0022604 42 0.033
regulation of growth GO:0040008 42 0.033
anterior posterior pattern specification GO:0009952 152 0.032
protein autoubiquitination GO:0051865 3 0.032
retina development in camera type eye GO:0060041 146 0.032
cellular component biogenesis GO:0044085 178 0.032
embryonic heart tube development GO:0035050 133 0.032
regulation of cell matrix adhesion GO:0001952 1 0.032
behavior GO:0007610 74 0.031
cytoplasm organization GO:0007028 4 0.031
startle response GO:0001964 4 0.031
single organism cellular localization GO:1902580 46 0.031
locomotor rhythm GO:0045475 3 0.031
negative chemotaxis GO:0050919 1 0.030
membrane organization GO:0061024 21 0.030
proteasomal protein catabolic process GO:0010498 2 0.030
nuclear transport GO:0051169 4 0.029
heart looping GO:0001947 94 0.029
positive regulation of metabolic process GO:0009893 108 0.029
signal transduction GO:0007165 455 0.029
convergent extension GO:0060026 118 0.029
phosphorus metabolic process GO:0006793 109 0.029
positive regulation of cellular metabolic process GO:0031325 94 0.029
axon development GO:0061564 166 0.029
single organism transport GO:0044765 206 0.029
neuron projection development GO:0031175 180 0.028
internal peptidyl lysine acetylation GO:0018393 2 0.028
cellular response to decreased oxygen levels GO:0036294 1 0.028
cell part morphogenesis GO:0032990 246 0.028
regulation of binding GO:0051098 3 0.027
morphogenesis of an epithelial sheet GO:0002011 49 0.027
regulation of developmental growth GO:0048638 38 0.027
regulation of protein transport GO:0051223 3 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
apoptotic process GO:0006915 116 0.026
hormone transport GO:0009914 2 0.026
neuron projection regeneration GO:0031102 16 0.026
regulation of biological quality GO:0065008 263 0.026
aging GO:0007568 2 0.026
lateral line system development GO:0048925 76 0.026
extracellular matrix constituent secretion GO:0070278 3 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
positive regulation of secretion GO:0051047 1 0.025
pole plasm assembly GO:0007315 4 0.025
er to golgi vesicle mediated transport GO:0006888 1 0.025
synaptic target recognition GO:0008039 1 0.025
establishment of vesicle localization GO:0051650 24 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
leukocyte homeostasis GO:0001776 2 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
g2 dna damage checkpoint GO:0031572 3 0.024
synapse organization GO:0050808 21 0.024
cell cell adhesion mediated by cadherin GO:0044331 5 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
dendrite development GO:0016358 9 0.024
angiogenesis GO:0001525 158 0.024
meiosis i GO:0007127 1 0.023
establishment of localization in cell GO:0051649 77 0.023
regulation of cell cell adhesion GO:0022407 13 0.023
protein dealkylation GO:0008214 2 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
small molecule metabolic process GO:0044281 77 0.023
peptide transport GO:0015833 1 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
ion homeostasis GO:0050801 41 0.023
lateral inhibition GO:0046331 1 0.023
olfactory lobe development GO:0021988 4 0.023
swimming behavior GO:0036269 8 0.023
protein import GO:0017038 3 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
negative regulation of biological process GO:0048519 304 0.022
myeloid cell differentiation GO:0030099 86 0.022
convergent extension involved in organogenesis GO:0060029 10 0.022
protein polyubiquitination GO:0000209 4 0.022
cellular protein catabolic process GO:0044257 4 0.022
regulation of cell shape GO:0008360 1 0.021
leukocyte proliferation GO:0070661 1 0.021
head development GO:0060322 303 0.021
autophagy GO:0006914 4 0.021
metal ion homeostasis GO:0055065 26 0.021
cell substrate adhesion GO:0031589 4 0.021
regulation of phosphorylation GO:0042325 26 0.021
reproductive process GO:0022414 40 0.021
response to chemical GO:0042221 320 0.021
hormone secretion GO:0046879 2 0.021
brain development GO:0007420 293 0.021
cell death GO:0008219 121 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
cellular response to hypoxia GO:0071456 1 0.020
cartilage development GO:0051216 96 0.020
positive regulation of signal transduction GO:0009967 56 0.020
tissue migration GO:0090130 37 0.020
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.020
compound eye development GO:0048749 2 0.020
convergent extension involved in gastrulation GO:0060027 71 0.020
skeletal system morphogenesis GO:0048705 102 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
multicellular organism reproduction GO:0032504 35 0.019
cell morphogenesis GO:0000902 289 0.019
adherens junction organization GO:0034332 4 0.019
meiotic cell cycle process GO:1903046 3 0.019
vascular endothelial growth factor signaling pathway GO:0038084 3 0.019
membrane invagination GO:0010324 1 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
cellular response to oxygen levels GO:0071453 1 0.019
response to uv GO:0009411 3 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
regulation of signal transduction GO:0009966 225 0.019
rna modification GO:0009451 2 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
regulation of localization GO:0032879 104 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
cellular response to starvation GO:0009267 1 0.018
forebrain cell migration GO:0021885 1 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
mechanosensory behavior GO:0007638 2 0.018
dna templated transcription elongation GO:0006354 3 0.018
myeloid cell development GO:0061515 32 0.018
neural plate morphogenesis GO:0001839 7 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
cellular component morphogenesis GO:0032989 336 0.017
cellular localization GO:0051641 97 0.017
embryonic hemopoiesis GO:0035162 53 0.017
generation of neurons GO:0048699 385 0.017
protein complex disassembly GO:0043241 1 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
protein secretion GO:0009306 1 0.017
response to stress GO:0006950 263 0.017
mesoderm morphogenesis GO:0048332 51 0.017
blood vessel development GO:0001568 246 0.017
rna biosynthetic process GO:0032774 181 0.017
neuron death GO:0070997 21 0.017
rho protein signal transduction GO:0007266 5 0.016
negative regulation of metabolic process GO:0009892 86 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
catecholamine metabolic process GO:0006584 2 0.016
innervation GO:0060384 3 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
cellular response to nutrient levels GO:0031669 2 0.016
protein dephosphorylation GO:0006470 3 0.016
transport GO:0006810 220 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
female gonad development GO:0008585 4 0.015
leukocyte activation GO:0045321 12 0.015
embryonic skeletal system development GO:0048706 97 0.015
meiotic nuclear division GO:0007126 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
neural crest cell differentiation GO:0014033 72 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
actomyosin structure organization GO:0031032 53 0.015
system process GO:0003008 185 0.015
liver development GO:0001889 96 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of programmed cell death GO:0043067 101 0.014
death GO:0016265 121 0.014
positive regulation of cell communication GO:0010647 56 0.014
centrosome cycle GO:0007098 1 0.014
histone h3 k4 methylation GO:0051568 2 0.014
regulation of rac protein signal transduction GO:0035020 1 0.014
post embryonic organ morphogenesis GO:0048563 1 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
immune system process GO:0002376 241 0.014
mitotic cell cycle GO:0000278 64 0.014
cell type specific apoptotic process GO:0097285 22 0.014
response to hydrogen peroxide GO:0042542 3 0.014
epithelial cell morphogenesis GO:0003382 2 0.014
hemopoiesis GO:0030097 183 0.014
development of primary female sexual characteristics GO:0046545 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
leukocyte differentiation GO:0002521 25 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
organic acid transport GO:0015849 9 0.013
erythrocyte development GO:0048821 24 0.013
amino acid transport GO:0006865 2 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
regulation of signaling GO:0023051 235 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
cellular cation homeostasis GO:0030003 17 0.013
lymphocyte differentiation GO:0030098 9 0.013
convergent extension involved in axis elongation GO:0060028 26 0.013
response to radiation GO:0009314 51 0.013
negative regulation of cell motility GO:2000146 17 0.013
regulation of organ growth GO:0046620 3 0.013
cellular response to external stimulus GO:0071496 2 0.013
negative regulation of nervous system development GO:0051961 22 0.013
negative regulation of cell migration GO:0030336 17 0.012
response to alkaloid GO:0043279 2 0.012
proteolysis GO:0006508 38 0.012
neurological system process GO:0050877 62 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
cellular protein modification process GO:0006464 100 0.012
positive regulation of developmental process GO:0051094 50 0.012
negative regulation of growth GO:0045926 10 0.012
negative regulation of response to cytokine stimulus GO:0060761 2 0.012
macroautophagy GO:0016236 1 0.012
sexual reproduction GO:0019953 36 0.012
positive regulation of cell activation GO:0050867 1 0.012
homeostasis of number of cells GO:0048872 62 0.012
cell cycle GO:0007049 93 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of catalytic activity GO:0050790 55 0.012
hepaticobiliary system development GO:0061008 98 0.012
regulation of protein targeting GO:1903533 2 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
circadian sleep wake cycle GO:0042745 2 0.012
regulation of cellular component movement GO:0051270 55 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
positive regulation of cell division GO:0051781 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
epithelial cell differentiation GO:0030855 116 0.012
cellular response to organic substance GO:0071310 105 0.012
regulation of locomotion GO:0040012 55 0.012
regulation of cell cell adhesion mediated by cadherin GO:2000047 5 0.012
regulation of protein modification process GO:0031399 29 0.012
neuromuscular process controlling balance GO:0050885 3 0.012
sensory system development GO:0048880 76 0.011
heart morphogenesis GO:0003007 156 0.011
negative regulation of wnt signaling pathway GO:0030178 30 0.011
lymphocyte homeostasis GO:0002260 1 0.011
mitotic metaphase plate congression GO:0007080 1 0.011
cardiac cell fate commitment GO:0060911 1 0.011
negative regulation of kinase activity GO:0033673 4 0.011
neural retina development GO:0003407 49 0.011
positive regulation of neuron death GO:1901216 1 0.011
regulation of myotube differentiation GO:0010830 2 0.011
regulation of molecular function GO:0065009 70 0.011
forebrain development GO:0030900 96 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
circadian rhythm GO:0007623 19 0.011
epithelium migration GO:0090132 25 0.011
positive regulation of cell cycle GO:0045787 3 0.011
macromolecule localization GO:0033036 54 0.011
regulation of neurogenesis GO:0050767 87 0.011
septum transversum development GO:0003343 4 0.011
chemotaxis GO:0006935 104 0.011
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.011
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
response to hexose GO:0009746 3 0.011
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.011
urogenital system development GO:0001655 97 0.011
developmental maturation GO:0021700 34 0.010
body morphogenesis GO:0010171 16 0.010
single organism membrane organization GO:0044802 20 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
negative regulation of developmental growth GO:0048640 9 0.010
establishment of localization GO:0051234 244 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
carboxylic acid transport GO:0046942 8 0.010
meiosis ii GO:0007135 1 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of endocrine process GO:0044060 2 0.010
intracellular signal transduction GO:0035556 85 0.010
negative regulation of tor signaling GO:0032007 2 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010

ikzf5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012