Danio rerio

0 known processes

il4r

interleukin 4 receptor

(Aliases: zgc:113063,il-4ra)

il4r biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.099
immune system process GO:0002376 241 0.098
neuron differentiation GO:0030182 353 0.095
regulation of cellular metabolic process GO:0031323 320 0.095
response to external stimulus GO:0009605 264 0.081
regulation of nitrogen compound metabolic process GO:0051171 251 0.080
morphogenesis of an epithelium GO:0002009 333 0.074
nitrogen compound metabolic process GO:0006807 319 0.074
intracellular signal transduction GO:0035556 85 0.074
larval development GO:0002164 2 0.072
regulation of metabolic process GO:0019222 359 0.072
immune system development GO:0002520 191 0.071
response to biotic stimulus GO:0009607 97 0.071
negative regulation of biological process GO:0048519 304 0.069
generation of neurons GO:0048699 385 0.067
regulation of multicellular organismal development GO:2000026 223 0.066
regulation of signal transduction GO:0009966 225 0.066
digestive tract development GO:0048565 265 0.064
phosphatidylinositol mediated signaling GO:0048015 2 0.063
heterocycle biosynthetic process GO:0018130 215 0.063
central nervous system development GO:0007417 387 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.060
regulation of cellular amino acid metabolic process GO:0006521 0 0.059
tube morphogenesis GO:0035239 349 0.057
cellular component movement GO:0006928 335 0.057
immune response GO:0006955 28 0.056
response to stress GO:0006950 263 0.056
chordate embryonic development GO:0043009 271 0.055
cellular component morphogenesis GO:0032989 336 0.053
positive regulation of cellular process GO:0048522 201 0.051
regulation of signaling GO:0023051 235 0.051
regulation of cellular amine metabolic process GO:0033238 0 0.051
regulation of rna metabolic process GO:0051252 224 0.050
rna metabolic process GO:0016070 219 0.050
cell migration involved in gastrulation GO:0042074 79 0.050
stem cell maintenance GO:0019827 4 0.049
aging GO:0007568 2 0.049
organic acid metabolic process GO:0006082 31 0.049
positive regulation of cell activation GO:0050867 1 0.048
amine metabolic process GO:0009308 2 0.048
brain development GO:0007420 293 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.047
gene expression GO:0010467 252 0.047
head development GO:0060322 303 0.046
cognition GO:0050890 1 0.046
organonitrogen compound metabolic process GO:1901564 74 0.046
regulation of primary metabolic process GO:0080090 311 0.046
signal transduction GO:0007165 455 0.045
regulation of cell activation GO:0050865 1 0.045
cell migration GO:0016477 237 0.044
cellular amine metabolic process GO:0044106 2 0.043
digestive system development GO:0055123 289 0.043
gastrulation GO:0007369 208 0.043
cell morphogenesis GO:0000902 289 0.043
regulation of establishment of protein localization GO:0070201 4 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.042
regulation of protein transport GO:0051223 3 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.041
regulation of cellular ketone metabolic process GO:0010565 7 0.040
heterocycle metabolic process GO:0046483 290 0.039
response to other organism GO:0051707 97 0.038
cellular amino acid metabolic process GO:0006520 7 0.038
cell surface receptor signaling pathway GO:0007166 325 0.038
gtp metabolic process GO:0046039 4 0.037
regulation of nervous system development GO:0051960 90 0.037
eye development GO:0001654 277 0.037
positive regulation of transport GO:0051050 2 0.037
regulation of gene expression GO:0010468 265 0.037
ameboidal type cell migration GO:0001667 143 0.037
negative regulation of cellular process GO:0048523 283 0.037
cell projection organization GO:0030030 284 0.037
regulation of synapse assembly GO:0051963 3 0.036
maintenance of location GO:0051235 4 0.036
single organism metabolic process GO:0044710 217 0.036
organic substance biosynthetic process GO:1901576 289 0.036
mesenchymal cell differentiation GO:0048762 87 0.035
cell part morphogenesis GO:0032990 246 0.035
positive regulation of cellular metabolic process GO:0031325 94 0.034
cellular protein metabolic process GO:0044267 129 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.034
cellular ketone metabolic process GO:0042180 11 0.034
regulation of jak stat cascade GO:0046425 3 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.033
guanosine containing compound catabolic process GO:1901069 2 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
nuclear transport GO:0051169 4 0.032
muscle structure development GO:0061061 196 0.032
response to virus GO:0009615 21 0.032
establishment of localization GO:0051234 244 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
regionalization GO:0003002 274 0.032
multicellular organism growth GO:0035264 4 0.032
organelle organization GO:0006996 227 0.032
cell death GO:0008219 121 0.031
multi organism process GO:0051704 134 0.031
response to external biotic stimulus GO:0043207 97 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
cellular biosynthetic process GO:0044249 286 0.031
regulation of response to stimulus GO:0048583 269 0.031
response to drug GO:0042493 3 0.031
digestive tract morphogenesis GO:0048546 231 0.031
response to chemical GO:0042221 320 0.030
regulation of metal ion transport GO:0010959 4 0.030
nucleocytoplasmic transport GO:0006913 4 0.030
organic cyclic compound metabolic process GO:1901360 301 0.030
blood vessel development GO:0001568 246 0.030
regulation of programmed cell death GO:0043067 101 0.030
single organism nuclear import GO:1902593 3 0.030
neuron development GO:0048666 262 0.030
cell motility GO:0048870 244 0.030
sensory organ development GO:0007423 393 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
t cell differentiation GO:0030217 6 0.030
biosynthetic process GO:0009058 294 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.029
determination of bilateral symmetry GO:0009855 204 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
positive regulation of apoptotic signaling pathway GO:2001235 1 0.028
neuron projection morphogenesis GO:0048812 161 0.028
locomotion GO:0040011 313 0.028
positive regulation of catabolic process GO:0009896 4 0.028
nucleic acid metabolic process GO:0090304 244 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of cytokine production GO:0001817 3 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
regulation of cell communication GO:0010646 232 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
regulation of developmental process GO:0050793 247 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
nucleic acid templated transcription GO:0097659 181 0.027
programmed cell death GO:0012501 119 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
positive regulation of cell cycle GO:0045787 3 0.027
protein targeting to nucleus GO:0044744 3 0.026
protein metabolic process GO:0019538 183 0.026
system process GO:0003008 185 0.026
regulation of cell differentiation GO:0045595 142 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
heart development GO:0007507 313 0.025
regulation of synapse organization GO:0050807 3 0.025
adherens junction organization GO:0034332 4 0.025
neuron projection development GO:0031175 180 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.025
regulation of binding GO:0051098 3 0.025
death GO:0016265 121 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
vasculature development GO:0001944 278 0.024
gtp catabolic process GO:0006184 2 0.024
oxoacid metabolic process GO:0043436 31 0.024
localization of cell GO:0051674 244 0.024
cellular response to external stimulus GO:0071496 2 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
protein import GO:0017038 3 0.024
cellular component biogenesis GO:0044085 178 0.024
regulation of apoptotic process GO:0042981 98 0.024
convergent extension GO:0060026 118 0.024
striated muscle tissue development GO:0014706 110 0.024
single organism organelle organization GO:1902589 199 0.024
embryonic organ development GO:0048568 381 0.024
response to nutrient GO:0007584 3 0.024
regulation of production of molecular mediator of immune response GO:0002700 1 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
gastrulation with mouth forming second GO:0001702 44 0.023
cell projection morphogenesis GO:0048858 244 0.023
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.023
positive regulation of immune effector process GO:0002699 3 0.023
cellular protein modification process GO:0006464 100 0.022
axonogenesis GO:0007409 152 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
gland development GO:0048732 143 0.022
phosphorus metabolic process GO:0006793 109 0.022
cell fate commitment GO:0045165 99 0.022
muscle organ development GO:0007517 101 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
protein localization to nucleus GO:0034504 3 0.022
protein modification process GO:0036211 100 0.022
skeletal muscle organ development GO:0060538 78 0.021
protein secretion GO:0009306 1 0.021
stem cell differentiation GO:0048863 117 0.021
release of sequestered calcium ion into cytosol GO:0051209 3 0.021
autophagy GO:0006914 4 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
regulation of peptidase activity GO:0052547 23 0.021
tyrosine phosphorylation of stat protein GO:0007260 1 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
mesenchyme development GO:0060485 127 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
cytosolic calcium ion transport GO:0060401 3 0.020
positive regulation of cytokine production GO:0001819 2 0.020
establishment of localization in cell GO:0051649 77 0.020
nuclear import GO:0051170 3 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
embryonic heart tube development GO:0035050 133 0.020
regulation of gtpase activity GO:0043087 2 0.020
mitochondrion organization GO:0007005 4 0.020
positive regulation of developmental process GO:0051094 50 0.020
guanosine containing compound metabolic process GO:1901068 4 0.019
single organism localization GO:1902578 225 0.019
endosomal transport GO:0016197 2 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
growth GO:0040007 174 0.019
mesenchymal cell development GO:0014031 78 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
positive regulation of cell death GO:0010942 29 0.019
somatic muscle development GO:0007525 4 0.019
axon development GO:0061564 166 0.019
production of molecular mediator of immune response GO:0002440 2 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.018
developmental growth GO:0048589 166 0.018
regulation of intracellular signal transduction GO:1902531 57 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
neurological system process GO:0050877 62 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
apoptotic process GO:0006915 116 0.018
regulation of protein targeting GO:1903533 2 0.018
cell substrate adhesion GO:0031589 4 0.018
positive regulation of biological process GO:0048518 253 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
zymogen activation GO:0031638 3 0.018
hemopoiesis GO:0030097 183 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
immune effector process GO:0002252 23 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
positive regulation of metabolic process GO:0009893 108 0.018
cellular response to biotic stimulus GO:0071216 3 0.017
regulation of biosynthetic process GO:0009889 250 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
organelle fusion GO:0048284 3 0.017
blood vessel morphogenesis GO:0048514 216 0.017
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
regulation of cell development GO:0060284 100 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
calcium ion transport into cytosol GO:0060402 3 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
positive regulation of secretion GO:0051047 1 0.017
response to carbohydrate GO:0009743 3 0.017
cellular response to nutrient levels GO:0031669 2 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
negative regulation of catabolic process GO:0009895 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
somite development GO:0061053 96 0.016
regulation of protein catabolic process GO:0042176 1 0.016
forebrain development GO:0030900 96 0.016
positive regulation of cell communication GO:0010647 56 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
positive regulation of gene expression GO:0010628 71 0.016
cellular protein catabolic process GO:0044257 4 0.016
macroautophagy GO:0016236 1 0.016
stem cell proliferation GO:0072089 4 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
adaptive immune response GO:0002250 5 0.016
angiogenesis GO:0001525 158 0.016
response to monosaccharide GO:0034284 3 0.016
tissue remodeling GO:0048771 4 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of cellular component organization GO:0051128 86 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
single organism membrane fusion GO:0044801 2 0.015
response to glucocorticoid GO:0051384 1 0.015
regulation of cell death GO:0010941 103 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
single organism cellular localization GO:1902580 46 0.015
negative regulation of cytokine production GO:0001818 1 0.015
regulation of protein metabolic process GO:0051246 56 0.015
anterior posterior pattern specification GO:0009952 152 0.015
cellular component assembly GO:0022607 170 0.015
phagocytosis GO:0006909 3 0.015
negative regulation of developmental process GO:0051093 65 0.015
cellular response to starvation GO:0009267 1 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
transport GO:0006810 220 0.015
calcium mediated signaling GO:0019722 2 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cytokinesis GO:0000910 3 0.015
antimicrobial humoral response GO:0019730 2 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
membrane fusion GO:0061025 2 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of cell shape GO:0008360 1 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
sequestering of calcium ion GO:0051208 3 0.014
leukocyte activation GO:0045321 12 0.014
transcription dna templated GO:0006351 181 0.014
regulation of inflammatory response GO:0050727 2 0.014
regulation of transcription dna templated GO:0006355 213 0.014
b cell activation GO:0042113 2 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
regulation of calcium ion transport GO:0051924 2 0.014
response to bacterium GO:0009617 58 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.014
stem cell development GO:0048864 82 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
ion transport GO:0006811 114 0.014
inner ear development GO:0048839 126 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
macromolecule modification GO:0043412 111 0.014
regulation of sodium ion transport GO:0002028 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
leukocyte differentiation GO:0002521 25 0.014
regulation of neurogenesis GO:0050767 87 0.014
negative regulation of metabolic process GO:0009892 86 0.014
mitotic cell cycle GO:0000278 64 0.014
lipid storage GO:0019915 1 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
response to organic substance GO:0010033 153 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
mononuclear cell proliferation GO:0032943 1 0.013
single organism transport GO:0044765 206 0.013
phosphorylation GO:0016310 69 0.013
regulation of autophagy GO:0010506 3 0.013
endoderm development GO:0007492 49 0.013
sensory organ morphogenesis GO:0090596 200 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
homeostatic process GO:0042592 142 0.013
rna biosynthetic process GO:0032774 181 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
small molecule metabolic process GO:0044281 77 0.013
negative regulation of kinase activity GO:0033673 4 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
defense response to virus GO:0051607 10 0.013
response to corticosteroid GO:0031960 1 0.013
positive regulation of neuron death GO:1901216 1 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
specification of symmetry GO:0009799 204 0.013
peptidyl serine modification GO:0018209 2 0.013
muscle tissue development GO:0060537 110 0.013
positive regulation of apoptotic process GO:0043065 29 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
chemosensory behavior GO:0007635 1 0.013
atp catabolic process GO:0006200 4 0.012
regulation of endopeptidase activity GO:0052548 23 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
negative regulation of signaling GO:0023057 96 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
eye morphogenesis GO:0048592 144 0.012
protein acetylation GO:0006473 2 0.012
regulation of catalytic activity GO:0050790 55 0.012
germ line stem cell maintenance GO:0030718 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
negative regulation of gene expression GO:0010629 65 0.012
stem cell division GO:0017145 1 0.012
response to glucose GO:0009749 3 0.012
cytoskeleton organization GO:0007010 96 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
epiboly GO:0090504 41 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
response to vitamin GO:0033273 3 0.011
liver development GO:0001889 96 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
negative regulation of defense response GO:0031348 2 0.011
cell matrix adhesion GO:0007160 4 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
t cell activation GO:0042110 6 0.011
regulation of molecular function GO:0065009 70 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
regulation of reproductive process GO:2000241 4 0.011
regulation of biological quality GO:0065008 263 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
exocytosis GO:0006887 1 0.011
retina development in camera type eye GO:0060041 146 0.011
heart contraction GO:0060047 71 0.011
protein import into nucleus GO:0006606 3 0.011
single organism intracellular transport GO:1902582 25 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
leukocyte proliferation GO:0070661 1 0.011
peptide transport GO:0015833 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
negative regulation of nuclear division GO:0051784 3 0.011
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.011
protein acylation GO:0043543 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
adult behavior GO:0030534 2 0.011
regulation of organ growth GO:0046620 3 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
fertilization GO:0009566 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
protein localization to plasma membrane GO:0072659 1 0.011
response to ketone GO:1901654 1 0.011
axon guidance GO:0007411 86 0.010
interspecies interaction between organisms GO:0044419 4 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
negative regulation of translation GO:0017148 1 0.010
defense response GO:0006952 47 0.010
action potential GO:0001508 19 0.010
circulatory system process GO:0003013 87 0.010
cellular amide metabolic process GO:0043603 4 0.010
regulation of hydrolase activity GO:0051336 28 0.010
sequestering of metal ion GO:0051238 3 0.010
cell cycle process GO:0022402 53 0.010
glucose homeostasis GO:0042593 1 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
camera type eye development GO:0043010 222 0.010
wnt signaling pathway GO:0016055 80 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
rna localization GO:0006403 4 0.010
cellular localization GO:0051641 97 0.010

il4r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013
disease of cellular proliferation DOID:14566 0 0.012