Danio rerio

72 known processes

il6st

interleukin 6 signal transducer

(Aliases: gp130)

il6st biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tyrosine phosphorylation of stat protein GO:0007260 1 0.879
Human
response to dsrna GO:0043331 7 0.851
response to external stimulus GO:0009605 264 0.567
regulation of jak stat cascade GO:0046425 3 0.547
Human
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.498
Human
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.476
Human
multicellular organismal metabolic process GO:0044236 2 0.471
immune system process GO:0002376 241 0.433
Human Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.424
Human Mouse Rat
response to glucocorticoid GO:0051384 1 0.417
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.385
Human
response to exogenous dsrna GO:0043330 6 0.379
cytokine mediated signaling pathway GO:0019221 7 0.369
Human Mouse Rat
response to stress GO:0006950 263 0.364
larval development GO:0002164 2 0.353
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.338
Human
cellular macromolecule metabolic process GO:0044260 391 0.281
Human Mouse
cell growth GO:0016049 57 0.268
signal transduction GO:0007165 455 0.267
Human Mouse Rat
morphogenesis of an epithelium GO:0002009 333 0.266
extrinsic apoptotic signaling pathway GO:0097191 3 0.262
regulation of cytokine production GO:0001817 3 0.261
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.260
Human
immune system development GO:0002520 191 0.259
Human Zebrafish
cellular response to lipopolysaccharide GO:0071222 3 0.241
regulation of signaling GO:0023051 235 0.235
Human Mouse
regulation of multicellular organismal metabolic process GO:0044246 2 0.216
response to chemical GO:0042221 320 0.206
Human Mouse Rat
regulation of response to stimulus GO:0048583 269 0.203
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.199
Human
negative regulation of cytokine production GO:0001818 1 0.195
regulation of signal transduction GO:0009966 225 0.190
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.185
regulation of cellular amino acid metabolic process GO:0006521 0 0.184
regulation of macromolecule metabolic process GO:0060255 317 0.183
Human
response to abiotic stimulus GO:0009628 122 0.181
collagen biosynthetic process GO:0032964 2 0.178
gastrulation GO:0007369 208 0.178
positive regulation of cytokine production GO:0001819 2 0.176
defense response to other organism GO:0098542 33 0.169
protein import into nucleus GO:0006606 3 0.167
defense response to virus GO:0051607 10 0.162
neuron development GO:0048666 262 0.159
growth GO:0040007 174 0.158
nucleocytoplasmic transport GO:0006913 4 0.157
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.156
positive regulation of biological process GO:0048518 253 0.155
intracellular signal transduction GO:0035556 85 0.154
Human
cell projection organization GO:0030030 284 0.153
regulation of cell communication GO:0010646 232 0.152
Human Mouse
negative regulation of biological process GO:0048519 304 0.152
Human
embryonic organ development GO:0048568 381 0.147
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.146
cell projection morphogenesis GO:0048858 244 0.145
regulation of nitrogen compound metabolic process GO:0051171 251 0.144
positive regulation of stress activated mapk cascade GO:0032874 3 0.144
regulation of gene expression GO:0010468 265 0.139
vasculature development GO:0001944 278 0.137
angiogenesis GO:0001525 158 0.136
cellular ketone metabolic process GO:0042180 11 0.130
nitrogen compound metabolic process GO:0006807 319 0.128
skeletal system development GO:0001501 181 0.127
response to external biotic stimulus GO:0043207 97 0.127
regulation of cellular ketone metabolic process GO:0010565 7 0.122
blood vessel development GO:0001568 246 0.119
defense response GO:0006952 47 0.116
tube morphogenesis GO:0035239 349 0.113
regulation of localization GO:0032879 104 0.109
Rat
hematopoietic or lymphoid organ development GO:0048534 191 0.107
Human Zebrafish
ion transport GO:0006811 114 0.106
sensory system development GO:0048880 76 0.106
multicellular organism growth GO:0035264 4 0.106
protein targeting to nucleus GO:0044744 3 0.106
protein localization to nucleus GO:0034504 3 0.103
multi organism process GO:0051704 134 0.103
protein complex localization GO:0031503 1 0.102
cell migration GO:0016477 237 0.101
Rat
posterior lateral line system development GO:0048915 46 0.101
response to lipopolysaccharide GO:0032496 13 0.100
blood vessel morphogenesis GO:0048514 216 0.100
chemotaxis GO:0006935 104 0.099
nucleic acid metabolic process GO:0090304 244 0.098
rna metabolic process GO:0016070 219 0.098
positive regulation of transport GO:0051050 2 0.097
regulation of protein localization to nucleus GO:1900180 2 0.097
aging GO:0007568 2 0.096
regulation of collagen metabolic process GO:0010712 2 0.096
gene expression GO:0010467 252 0.095
regulation of macromolecule biosynthetic process GO:0010556 225 0.094
endocrine pancreas development GO:0031018 27 0.094
jak stat cascade GO:0007259 5 0.094
Human
defense response to bacterium GO:0042742 22 0.093
nuclear transport GO:0051169 4 0.092
cellular component movement GO:0006928 335 0.092
Rat
regulation of protein targeting GO:1903533 2 0.090
cellular nitrogen compound metabolic process GO:0034641 290 0.090
dorsal ventral pattern formation GO:0009953 125 0.090
response to organic substance GO:0010033 153 0.089
Human Mouse Rat
positive regulation of cell proliferation GO:0008284 15 0.088
Human Mouse
regulation of intracellular signal transduction GO:1902531 57 0.088
Human
digestive system development GO:0055123 289 0.087
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.086
cell motility GO:0048870 244 0.084
Rat
nitric oxide metabolic process GO:0046209 2 0.082
positive regulation of cell communication GO:0010647 56 0.081
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.081
cellular macromolecule biosynthetic process GO:0034645 224 0.080
positive regulation of signal transduction GO:0009967 56 0.079
Human
protein import GO:0017038 3 0.079
embryonic organ morphogenesis GO:0048562 274 0.079
response to biotic stimulus GO:0009607 97 0.078
sensory organ development GO:0007423 393 0.078
response to other organism GO:0051707 97 0.077
oxoacid metabolic process GO:0043436 31 0.077
regulation of immune system process GO:0002682 34 0.077
Human
regulation of biosynthetic process GO:0009889 250 0.076
regulation of establishment of protein localization GO:0070201 4 0.076
collagen metabolic process GO:0032963 2 0.075
mechanosensory lateral line system development GO:0048881 49 0.074
digestive tract morphogenesis GO:0048546 231 0.072
macromolecule modification GO:0043412 111 0.072
Human
endocrine system development GO:0035270 65 0.071
lateral line development GO:0048882 66 0.071
multicellular organismal macromolecule metabolic process GO:0044259 2 0.071
regulation of protein transport GO:0051223 3 0.071
transport GO:0006810 220 0.070
posterior lateral line development GO:0048916 38 0.070
heart development GO:0007507 313 0.070
regulation of multicellular organismal process GO:0051239 277 0.070
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.069
Human
positive regulation of neuron apoptotic process GO:0043525 1 0.067
regulation of ion transport GO:0043269 22 0.067
positive regulation of cellular catabolic process GO:0031331 3 0.066
cellular nitrogen compound biosynthetic process GO:0044271 218 0.066
regulation of primary metabolic process GO:0080090 311 0.066
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.065
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.065
regionalization GO:0003002 274 0.065
regulation of protein import into nucleus GO:0042306 2 0.065
sensory perception of chemical stimulus GO:0007606 3 0.064
organic substance biosynthetic process GO:1901576 289 0.063
cellular response to molecule of bacterial origin GO:0071219 3 0.063
protein modification process GO:0036211 100 0.063
Human
cytokinesis GO:0000910 3 0.062
regulation of cellular biosynthetic process GO:0031326 245 0.062
cellular extravasation GO:0045123 1 0.062
response to arsenic containing substance GO:0046685 5 0.061
cellular response to external stimulus GO:0071496 2 0.061
cellular amino acid metabolic process GO:0006520 7 0.061
cellular component assembly GO:0022607 170 0.061
lateral line system development GO:0048925 76 0.060
regulation of epithelial cell proliferation GO:0050678 3 0.060
response to mechanical stimulus GO:0009612 24 0.058
developmental growth GO:0048589 166 0.058
establishment of localization GO:0051234 244 0.057
chordate embryonic development GO:0043009 271 0.057
regulation of cellular metabolic process GO:0031323 320 0.056
Human
phosphate containing compound metabolic process GO:0006796 108 0.056
Human
apoptotic process GO:0006915 116 0.056
nucleobase containing compound biosynthetic process GO:0034654 205 0.056
ameboidal type cell migration GO:0001667 143 0.056
chronic inflammatory response GO:0002544 1 0.055
stem cell maintenance GO:0019827 4 0.055
taxis GO:0042330 109 0.055
response to nutrient GO:0007584 3 0.054
Rat
regulation of reactive oxygen species metabolic process GO:2000377 2 0.054
system process GO:0003008 185 0.054
embryonic skeletal system development GO:0048706 97 0.054
membrane invagination GO:0010324 1 0.052
positive regulation of molecular function GO:0044093 33 0.051
axonogenesis GO:0007409 152 0.051
establishment of protein localization to organelle GO:0072594 4 0.051
hemopoiesis GO:0030097 183 0.050
Human Zebrafish
neuromuscular synaptic transmission GO:0007274 2 0.050
production of molecular mediator of immune response GO:0002440 2 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.050
locomotion GO:0040011 313 0.049
Rat
cell part morphogenesis GO:0032990 246 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.049
regulation of response to cytokine stimulus GO:0060759 3 0.049
Human
liver development GO:0001889 96 0.048
cell morphogenesis involved in differentiation GO:0000904 195 0.048
phosphorylation GO:0016310 69 0.048
Human
cellular carbohydrate metabolic process GO:0044262 4 0.048
Mouse
response to molecule of bacterial origin GO:0002237 14 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.048
peripheral nervous system neuron differentiation GO:0048934 28 0.047
antimicrobial humoral response GO:0019730 2 0.047
carbohydrate derivative biosynthetic process GO:1901137 43 0.046
regulation of cellular amine metabolic process GO:0033238 0 0.046
positive regulation of cell cycle GO:0045787 3 0.046
muscle structure development GO:0061061 196 0.046
regulation of multicellular organismal development GO:2000026 223 0.045
axon development GO:0061564 166 0.045
cellular component morphogenesis GO:0032989 336 0.044
somatic muscle development GO:0007525 4 0.044
regulation of synapse assembly GO:0051963 3 0.044
negative regulation of metabolic process GO:0009892 86 0.043
localization of cell GO:0051674 244 0.043
Rat
stem cell division GO:0017145 1 0.043
positive regulation of catabolic process GO:0009896 4 0.043
camera type eye development GO:0043010 222 0.042
enzyme linked receptor protein signaling pathway GO:0007167 106 0.042
Human
response to hormone GO:0009725 48 0.042
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
regulation of production of molecular mediator of immune response GO:0002700 1 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.042
cell morphogenesis GO:0000902 289 0.041
negative regulation of cellular process GO:0048523 283 0.041
Human
positive regulation of map kinase activity GO:0043406 3 0.041
regulation of intracellular protein transport GO:0033157 3 0.041
digestive tract development GO:0048565 265 0.041
positive regulation of metabolic process GO:0009893 108 0.041
Human
innate immune response GO:0045087 13 0.041
aromatic compound biosynthetic process GO:0019438 217 0.040
phosphorus metabolic process GO:0006793 109 0.040
Human
heterocycle biosynthetic process GO:0018130 215 0.040
regulation of response to biotic stimulus GO:0002831 2 0.040
epithelial tube morphogenesis GO:0060562 148 0.040
positive regulation of signaling GO:0023056 56 0.040
Human
biosynthetic process GO:0009058 294 0.040
positive regulation of apoptotic signaling pathway GO:2001235 1 0.040
regulation of binding GO:0051098 3 0.040
positive regulation of jak stat cascade GO:0046427 2 0.040
Human
organelle organization GO:0006996 227 0.040
synaptic growth at neuromuscular junction GO:0051124 2 0.040
stem cell differentiation GO:0048863 117 0.040
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.039
response to corticosteroid GO:0031960 1 0.039
single organism nuclear import GO:1902593 3 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
translational initiation GO:0006413 3 0.039
positive regulation of jnk cascade GO:0046330 3 0.039
sensory organ morphogenesis GO:0090596 200 0.038
response to amino acid GO:0043200 2 0.038
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.038
secondary metabolic process GO:0019748 3 0.038
regulation of developmental process GO:0050793 247 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.038
establishment of localization in cell GO:0051649 77 0.038
negative regulation of kinase activity GO:0033673 4 0.037
single organism transport GO:0044765 206 0.037
cellular response to starvation GO:0009267 1 0.037
central nervous system development GO:0007417 387 0.037
Mouse
carboxylic acid metabolic process GO:0019752 22 0.037
regulation of synapse organization GO:0050807 3 0.036
tissue remodeling GO:0048771 4 0.036
cellular biosynthetic process GO:0044249 286 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
heterocycle metabolic process GO:0046483 290 0.036
regulation of response to stress GO:0080134 36 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.036
single organism organelle organization GO:1902589 199 0.036
cellular protein modification process GO:0006464 100 0.036
Human
cellular localization GO:0051641 97 0.035
head development GO:0060322 303 0.035
synaptic target recognition GO:0008039 1 0.035
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.035
anion transport GO:0006820 38 0.035
phagocytosis engulfment GO:0006911 1 0.035
cell death GO:0008219 121 0.035
maintenance of location GO:0051235 4 0.035
cell migration involved in gastrulation GO:0042074 79 0.035
positive regulation of response to stimulus GO:0048584 80 0.035
regulation of cellular protein metabolic process GO:0032268 52 0.035
Human
response to nitrogen compound GO:1901698 19 0.035
nitric oxide biosynthetic process GO:0006809 2 0.034
cellular response to nutrient levels GO:0031669 2 0.034
hair cell differentiation GO:0035315 32 0.034
regulation of reproductive process GO:2000241 4 0.034
positive regulation of multicellular organismal process GO:0051240 52 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
peripheral nervous system neuron development GO:0048935 22 0.034
regulation of rna metabolic process GO:0051252 224 0.033
cellular response to cytokine stimulus GO:0071345 7 0.033
Human Mouse Rat
interspecies interaction between organisms GO:0044419 4 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
skeletal system morphogenesis GO:0048705 102 0.033
response to peptide hormone GO:0043434 6 0.033
cellular response to stress GO:0033554 62 0.033
defense response to gram positive bacterium GO:0050830 6 0.033
ribonucleoside monophosphate catabolic process GO:0009158 4 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
amine metabolic process GO:0009308 2 0.033
regulation of cell proliferation GO:0042127 37 0.033
Human Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
positive regulation of cell division GO:0051781 2 0.032
multi organism cellular process GO:0044764 2 0.032
nuclear import GO:0051170 3 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.032
organ regeneration GO:0031100 1 0.031
response to oxygen containing compound GO:1901700 55 0.031
signal transduction in absence of ligand GO:0038034 1 0.031
response to bacterium GO:0009617 58 0.031
peptidyl tyrosine modification GO:0018212 5 0.031
Human
muscle cell differentiation GO:0042692 139 0.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.031
positive regulation of myeloid cell differentiation GO:0045639 2 0.031
determination of bilateral symmetry GO:0009855 204 0.031
cell proliferation GO:0008283 80 0.031
Human Mouse
heart morphogenesis GO:0003007 156 0.030
viral process GO:0016032 1 0.030
phagocytosis GO:0006909 3 0.030
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.030
negative regulation of developmental process GO:0051093 65 0.030
alcohol biosynthetic process GO:0046165 2 0.030
cellular component biogenesis GO:0044085 178 0.030
response to lipid GO:0033993 60 0.030
organic cyclic compound biosynthetic process GO:1901362 223 0.030
regulation of glucose transport GO:0010827 1 0.029
cellular amine metabolic process GO:0044106 2 0.029
embryonic hemopoiesis GO:0035162 53 0.029
Zebrafish
lipid storage GO:0019915 1 0.029
zymogen activation GO:0031638 3 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
brain development GO:0007420 293 0.029
negative regulation of map kinase activity GO:0043407 2 0.028
ventral spinal cord development GO:0021517 35 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
small molecule metabolic process GO:0044281 77 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.028
b cell mediated immunity GO:0019724 3 0.028
gtp metabolic process GO:0046039 4 0.028
phosphatidylinositol mediated signaling GO:0048015 2 0.028
regulation of protein catabolic process GO:0042176 1 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.028
single organism metabolic process GO:0044710 217 0.028
Mouse Rat
protein metabolic process GO:0019538 183 0.028
Human
immune effector process GO:0002252 23 0.028
peptide transport GO:0015833 1 0.028
amino acid transport GO:0006865 2 0.028
atp catabolic process GO:0006200 4 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
cognition GO:0050890 1 0.027
wnt signaling pathway GO:0016055 80 0.027
cell substrate adhesion GO:0031589 4 0.027
signal transduction by phosphorylation GO:0023014 18 0.027
regeneration GO:0031099 91 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.027
neurological system process GO:0050877 62 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
intestinal absorption GO:0050892 2 0.027
negative regulation of multicellular organismal process GO:0051241 69 0.027
post embryonic organ development GO:0048569 4 0.026
protein phosphorylation GO:0006468 47 0.026
Human
response to wounding GO:0009611 116 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
melanin metabolic process GO:0006582 2 0.026
immunoglobulin mediated immune response GO:0016064 3 0.026
regulation of neuron projection regeneration GO:0070570 7 0.026
regulation of molecular function GO:0065009 70 0.026
peptidyl serine phosphorylation GO:0018105 1 0.026
response to organic cyclic compound GO:0014070 51 0.026
developmental growth involved in morphogenesis GO:0060560 86 0.025
positive regulation of gliogenesis GO:0014015 2 0.025
Mouse
cardiac conduction GO:0061337 3 0.025
regulation of metabolic process GO:0019222 359 0.025
Human
positive regulation of immune effector process GO:0002699 3 0.025
regulation of response to nutrient levels GO:0032107 1 0.025
regulation of protein phosphorylation GO:0001932 18 0.025
Human
erythrocyte differentiation GO:0030218 54 0.025
negative chemotaxis GO:0050919 1 0.025
regulation of biological quality GO:0065008 263 0.025
Rat
cellular protein catabolic process GO:0044257 4 0.025
convergent extension GO:0060026 118 0.024
negative regulation of cellular catabolic process GO:0031330 3 0.024
negative regulation of response to cytokine stimulus GO:0060761 2 0.024
Human
cellular response to extracellular stimulus GO:0031668 2 0.024
cation transmembrane transport GO:0098655 65 0.024
embryonic skeletal system morphogenesis GO:0048704 93 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
nucleic acid templated transcription GO:0097659 181 0.024
stem cell proliferation GO:0072089 4 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
macromolecule localization GO:0033036 54 0.023
regulation of catalytic activity GO:0050790 55 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
regulation of transcription dna templated GO:0006355 213 0.023
macromolecule catabolic process GO:0009057 15 0.023
transcription dna templated GO:0006351 181 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
determination of left right symmetry GO:0007368 179 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
mapk cascade GO:0000165 18 0.023
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.023
embryonic skeletal joint development GO:0072498 3 0.023
regulation of endothelial cell proliferation GO:0001936 1 0.023
negative regulation of cell communication GO:0010648 96 0.022
Human
type i interferon production GO:0032606 2 0.022
neuron projection development GO:0031175 180 0.022
compound eye development GO:0048749 2 0.022
regulation of hormone secretion GO:0046883 2 0.022
neuron differentiation GO:0030182 353 0.022
positive regulation of protein kinase b signaling GO:0051897 1 0.022
wound healing GO:0042060 90 0.022
regulation of inflammatory response GO:0050727 2 0.022
death GO:0016265 121 0.022
rna biosynthetic process GO:0032774 181 0.022
neuroblast proliferation GO:0007405 2 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
muscle tissue development GO:0060537 110 0.022
inositol lipid mediated signaling GO:0048017 2 0.022
posterior lateral line neuromast development GO:0048919 20 0.022
positive regulation of cellular process GO:0048522 201 0.022
fatty acid transport GO:0015908 1 0.022
regulation of transport GO:0051049 45 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
regulation of cell differentiation GO:0045595 142 0.022
stem cell development GO:0048864 82 0.022
macroautophagy GO:0016236 1 0.022
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
reactive oxygen species biosynthetic process GO:1903409 1 0.021
negative regulation of catabolic process GO:0009895 3 0.021
proepicardium development GO:0003342 4 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
organelle assembly GO:0070925 110 0.021
response to cold GO:0009409 4 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.021
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.021
retina development in camera type eye GO:0060041 146 0.021
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.021
mitochondrion organization GO:0007005 4 0.021
cellular amide metabolic process GO:0043603 4 0.021
superoxide metabolic process GO:0006801 2 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
regulation of protein metabolic process GO:0051246 56 0.021
Human
cell fate commitment GO:0045165 99 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
hormone transport GO:0009914 2 0.021
tube closure GO:0060606 1 0.020
positive regulation of catalytic activity GO:0043085 25 0.020
positive regulation of neuron death GO:1901216 1 0.020
peripheral nervous system development GO:0007422 55 0.020
regulation of cell death GO:0010941 103 0.020
regulation of cellular component organization GO:0051128 86 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
regulation of programmed cell death GO:0043067 101 0.020
regulation of dna replication GO:0006275 3 0.020
positive regulation of cell activation GO:0050867 1 0.020
Human
single organism localization GO:1902578 225 0.019
gland development GO:0048732 143 0.019
positive regulation of cell substrate adhesion GO:0010811 1 0.019
cilium morphogenesis GO:0060271 85 0.019
neuromast development GO:0048884 46 0.019
skeletal muscle organ development GO:0060538 78 0.019
peptidyl amino acid modification GO:0018193 16 0.019
Human
internal peptidyl lysine acetylation GO:0018393 2 0.019
gtp catabolic process GO:0006184 2 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
regulation of membrane potential GO:0042391 23 0.019
regulation of cytokine biosynthetic process GO:0042035 1 0.019
regulation of leukocyte mediated immunity GO:0002703 1 0.019
energy reserve metabolic process GO:0006112 2 0.019
Mouse
neuron projection morphogenesis GO:0048812 161 0.019
autophagy GO:0006914 4 0.019
response to peptide GO:1901652 6 0.019
cellular response to organic substance GO:0071310 105 0.019
Human Mouse Rat
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.019
eye development GO:0001654 277 0.018
endoderm development GO:0007492 49 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
glial cell proliferation GO:0014009 4 0.018
germ line stem cell maintenance GO:0030718 2 0.018
cell division GO:0051301 20 0.018
defense response to fungus GO:0050832 2 0.018
dicarboxylic acid transport GO:0006835 1 0.018
vesicle mediated transport GO:0016192 22 0.018
response to drug GO:0042493 3 0.018
positive regulation of secretion GO:0051047 1 0.018
sensory perception GO:0007600 39 0.018
response to carbohydrate GO:0009743 3 0.018
positive regulation of intracellular signal transduction GO:1902533 15 0.018
Human
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
positive regulation of multi organism process GO:0043902 3 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
axon guidance GO:0007411 86 0.018
regulation of growth GO:0040008 42 0.018
positive regulation of programmed cell death GO:0043068 29 0.018
positive regulation of immune system process GO:0002684 17 0.018
Human
regulation of cytokine mediated signaling pathway GO:0001959 3 0.018
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
fertilization GO:0009566 3 0.017
negative regulation of cell differentiation GO:0045596 46 0.017
regulation of tube size GO:0035150 2 0.017
single fertilization GO:0007338 3 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
organic acid catabolic process GO:0016054 3 0.017
nik nf kappab signaling GO:0038061 1 0.017

il6st disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
disease of cellular proliferation DOID:14566 0 0.027
disease of metabolism DOID:0014667 0 0.018
Human