Danio rerio

23 known processes

ins

preproinsulin

(Aliases: zgc:109842)

ins biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound biosynthetic process GO:0019438 217 0.963
Mouse
regulation of biosynthetic process GO:0009889 250 0.959
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.947
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.939
Mouse
negative regulation of cellular process GO:0048523 283 0.909
Mouse
organic substance biosynthetic process GO:1901576 289 0.880
Mouse
negative regulation of biological process GO:0048519 304 0.841
regulation of cellular metabolic process GO:0031323 320 0.839
Mouse
type b pancreatic cell development GO:0003323 4 0.836
regulation of rna biosynthetic process GO:2001141 213 0.823
Mouse
nitrogen compound metabolic process GO:0006807 319 0.821
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.815
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.785
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.784
Mouse
nucleic acid templated transcription GO:0097659 181 0.784
Mouse
regulation of metabolic process GO:0019222 359 0.772
Mouse
nucleic acid metabolic process GO:0090304 244 0.765
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.763
Mouse
biosynthetic process GO:0009058 294 0.758
Mouse
cellular biosynthetic process GO:0044249 286 0.757
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.727
Mouse
regulation of transcription dna templated GO:0006355 213 0.717
Mouse
regulation of gene expression GO:0010468 265 0.709
Mouse
glucose homeostasis GO:0042593 1 0.695
regulation of primary metabolic process GO:0080090 311 0.688
Mouse
single organism metabolic process GO:0044710 217 0.655
Mouse
glandular epithelial cell differentiation GO:0002067 9 0.645
positive regulation of biological process GO:0048518 253 0.639
Mouse
gene expression GO:0010467 252 0.610
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.600
Mouse
heterocycle biosynthetic process GO:0018130 215 0.596
Mouse
pancreatic a cell differentiation GO:0003310 6 0.575
enteroendocrine cell differentiation GO:0035883 9 0.570
regulation of hormone secretion GO:0046883 2 0.531
regulation of rna metabolic process GO:0051252 224 0.520
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.513
Mouse
response to nutrient levels GO:0031667 10 0.506
cellular macromolecule biosynthetic process GO:0034645 224 0.500
Mouse
regulation of response to stimulus GO:0048583 269 0.495
regulation of macromolecule metabolic process GO:0060255 317 0.492
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.480
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.479
Mouse
macromolecule biosynthetic process GO:0009059 227 0.474
Mouse
pancreatic a cell development GO:0003322 2 0.432
regulation of neuron migration GO:2001222 2 0.425
negative regulation of metabolic process GO:0009892 86 0.423
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.417
endocrine system development GO:0035270 65 0.409
rna biosynthetic process GO:0032774 181 0.397
Mouse
vasculature development GO:0001944 278 0.377
nitrogen compound transport GO:0071705 23 0.357
positive regulation of glial cell differentiation GO:0045687 1 0.352
positive regulation of cellular metabolic process GO:0031325 94 0.342
Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.316
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.295
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.284
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.283
Mouse
positive regulation of camp metabolic process GO:0030816 2 0.281
lipid catabolic process GO:0016042 4 0.279
Mouse
peptide transport GO:0015833 1 0.270
negative regulation of gene expression GO:0010629 65 0.267
Mouse
single organism biosynthetic process GO:0044711 71 0.264
positive regulation of cellular process GO:0048522 201 0.262
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.256
Mouse
negative regulation of cell communication GO:0010648 96 0.239
type b pancreatic cell differentiation GO:0003309 8 0.238
neural tube patterning GO:0021532 33 0.237
transcription dna templated GO:0006351 181 0.237
Mouse
cell motility GO:0048870 244 0.226
death GO:0016265 121 0.225
Mouse
regulation of localization GO:0032879 104 0.223
rna metabolic process GO:0016070 219 0.223
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.223
Mouse
regulation of multicellular organism growth GO:0040014 4 0.218
carbohydrate homeostasis GO:0033500 1 0.213
foregut morphogenesis GO:0007440 4 0.211
cell migration GO:0016477 237 0.197
transcription from rna polymerase ii promoter GO:0006366 80 0.195
Mouse
regulation of cell death GO:0010941 103 0.194
endocrine pancreas development GO:0031018 27 0.192
monovalent inorganic cation transport GO:0015672 42 0.188
negative regulation of cellular biosynthetic process GO:0031327 55 0.187
Mouse
regulation of retina development in camera type eye GO:1902866 2 0.179
homeostatic process GO:0042592 142 0.178
gland development GO:0048732 143 0.176
response to drug GO:0042493 3 0.175
regulation of signal transduction GO:0009966 225 0.174
Mouse
hormone secretion GO:0046879 2 0.170
heterocycle metabolic process GO:0046483 290 0.169
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.164
Mouse
signal transduction GO:0007165 455 0.159
Mouse
pancreas development GO:0031016 84 0.158
response to nicotine GO:0035094 2 0.156
sensory organ development GO:0007423 393 0.153
positive regulation of gene expression GO:0010628 71 0.151
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.151
endocardium formation GO:0060214 1 0.148
intracellular signal transduction GO:0035556 85 0.148
Mouse
positive regulation of cell communication GO:0010647 56 0.147
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.146
Mouse
cellular response to chemical stimulus GO:0070887 157 0.144
Mouse
negative regulation of heart contraction GO:0045822 2 0.144
negative regulation of secretion GO:0051048 2 0.142
chemical homeostasis GO:0048878 49 0.142
positive regulation of biosynthetic process GO:0009891 68 0.136
regulation of signaling GO:0023051 235 0.136
Mouse
amide transport GO:0042886 12 0.135
alcohol biosynthetic process GO:0046165 2 0.135
regulation of biological quality GO:0065008 263 0.134
cellular response to external stimulus GO:0071496 2 0.131
embryonic hemopoiesis GO:0035162 53 0.128
stem cell proliferation GO:0072089 4 0.128
positive regulation of epithelial cell differentiation GO:0030858 2 0.127
positive regulation of transcription dna templated GO:0045893 57 0.125
spinal cord motor neuron cell fate specification GO:0021520 8 0.123
cell fate specification involved in pattern specification GO:0060573 3 0.122
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.122
negative regulation of signaling GO:0023057 96 0.121
positive regulation of signaling GO:0023056 56 0.121
Mouse
regulation of multicellular organismal development GO:2000026 223 0.121
protein metabolic process GO:0019538 183 0.120
Mouse
regulation of catalytic activity GO:0050790 55 0.119
Mouse
small molecule metabolic process GO:0044281 77 0.118
regulation of developmental process GO:0050793 247 0.116
positive regulation of developmental process GO:0051094 50 0.115
regulation of programmed cell death GO:0043067 101 0.114
positive regulation of cellular catabolic process GO:0031331 3 0.114
digestive system development GO:0055123 289 0.114
single organism transport GO:0044765 206 0.113
proteolysis GO:0006508 38 0.113
response to stress GO:0006950 263 0.112
Zebrafish Mouse
growth GO:0040007 174 0.110
Zebrafish
cellular response to organic substance GO:0071310 105 0.110
Mouse
regulation of multicellular organismal process GO:0051239 277 0.106
cell death GO:0008219 121 0.105
Mouse
negative regulation of signal transduction GO:0009968 94 0.103
negative regulation of multicellular organismal process GO:0051241 69 0.100
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.099
embryonic organ development GO:0048568 381 0.099
Zebrafish
regulation of proteolysis GO:0030162 24 0.099
cellular response to organic cyclic compound GO:0071407 38 0.098
liver development GO:0001889 96 0.095
ear development GO:0043583 127 0.095
regulation of response to stress GO:0080134 36 0.093
epithelial cell differentiation GO:0030855 116 0.092
regulation of macromolecule biosynthetic process GO:0010556 225 0.091
Mouse
negative regulation of molecular function GO:0044092 23 0.090
cellular protein catabolic process GO:0044257 4 0.089
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.088
phosphorus metabolic process GO:0006793 109 0.087
Mouse
response to oxygen containing compound GO:1901700 55 0.087
response to carbohydrate GO:0009743 3 0.086
determination of left right symmetry GO:0007368 179 0.086
response to hormone GO:0009725 48 0.085
Mouse Rat
regulation of fatty acid metabolic process GO:0019217 1 0.084
multicellular organism growth GO:0035264 4 0.084
regulation of cellular ph GO:0030641 1 0.083
cell differentiation in spinal cord GO:0021515 40 0.082
response to organic substance GO:0010033 153 0.082
periodic partitioning GO:0007365 1 0.080
positive regulation of catabolic process GO:0009896 4 0.079
positive regulation of apoptotic process GO:0043065 29 0.079
cellular response to drug GO:0035690 1 0.079
cell cell signaling GO:0007267 52 0.078
auditory receptor cell fate determination GO:0042668 2 0.078
positive regulation of macromolecule metabolic process GO:0010604 93 0.075
Mouse
cell growth GO:0016049 57 0.075
positive regulation of cellular biosynthetic process GO:0031328 68 0.075
response to biotic stimulus GO:0009607 97 0.075
Mouse
embryonic foregut morphogenesis GO:0048617 1 0.074
localization of cell GO:0051674 244 0.074
negative regulation of kinase activity GO:0033673 4 0.072
regulation of molecular function GO:0065009 70 0.070
Mouse
regulation of cellular component movement GO:0051270 55 0.070
cellular response to extracellular stimulus GO:0031668 2 0.070
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.069
positive regulation of neuron migration GO:2001224 2 0.069
regulation of apoptotic process GO:0042981 98 0.067
cellular component movement GO:0006928 335 0.065
optic placode formation involved in camera type eye formation GO:0046619 3 0.065
enzyme linked receptor protein signaling pathway GO:0007167 106 0.065
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.065
programmed cell death GO:0012501 119 0.064
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.063
cell proliferation GO:0008283 80 0.063
regulation of cell communication GO:0010646 232 0.062
Mouse
lipid oxidation GO:0034440 1 0.062
single organism localization GO:1902578 225 0.062
hindbrain development GO:0030902 91 0.061
inner ear development GO:0048839 126 0.060
regulation of neural retina development GO:0061074 2 0.059
transport GO:0006810 220 0.059
positive regulation of metabolic process GO:0009893 108 0.059
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.058
regulation of phosphate metabolic process GO:0019220 43 0.058
Mouse
specification of symmetry GO:0009799 204 0.058
organic substance transport GO:0071702 58 0.056
negative regulation of phosphate metabolic process GO:0045936 13 0.056
negative regulation of rna metabolic process GO:0051253 48 0.055
Mouse
cell migration involved in heart formation GO:0060974 10 0.055
lipid metabolic process GO:0006629 52 0.054
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.054
ion transmembrane transport GO:0034220 91 0.054
iron ion homeostasis GO:0055072 4 0.054
steroid biosynthetic process GO:0006694 5 0.053
otolith development GO:0048840 32 0.053
response to ketone GO:1901654 1 0.053
response to alkaloid GO:0043279 2 0.053
negative regulation of transcription dna templated GO:0045892 45 0.052
Mouse
positive regulation of response to stimulus GO:0048584 80 0.052
Mouse
heart development GO:0007507 313 0.051
positive regulation of multicellular organismal process GO:0051240 52 0.051
regionalization GO:0003002 274 0.051
Zebrafish
response to nutrient GO:0007584 3 0.051
organophosphate biosynthetic process GO:0090407 23 0.050
positive regulation of signal transduction GO:0009967 56 0.050
Mouse
determination of bilateral symmetry GO:0009855 204 0.050
response to inorganic substance GO:0010035 38 0.050
oligodendrocyte cell fate specification GO:0021778 4 0.049
positive regulation of gliogenesis GO:0014015 2 0.049
response to extracellular stimulus GO:0009991 10 0.048
hormone transport GO:0009914 2 0.048
positive regulation of blood circulation GO:1903524 2 0.047
negative regulation of blood circulation GO:1903523 2 0.047
organonitrogen compound metabolic process GO:1901564 74 0.046
positive regulation of cellular component biogenesis GO:0044089 3 0.046
membrane hyperpolarization GO:0060081 1 0.046
catabolic process GO:0009056 32 0.046
Mouse
intramembranous ossification GO:0001957 3 0.046
anterior posterior pattern specification GO:0009952 152 0.046
Zebrafish
pectoral fin development GO:0033339 50 0.045
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.045
response to organic cyclic compound GO:0014070 51 0.045
Rat
negative regulation of nucleic acid templated transcription GO:1903507 45 0.045
Mouse
regulation of inflammatory response GO:0050727 2 0.044
regulation of protein catabolic process GO:0042176 1 0.044
response to endogenous stimulus GO:0009719 83 0.044
Mouse Rat
regulation of sodium ion transport GO:0002028 2 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
blood vessel development GO:0001568 246 0.043
blood vessel morphogenesis GO:0048514 216 0.043
atrioventricular valve formation GO:0003190 3 0.043
ventral spinal cord interneuron fate commitment GO:0060579 3 0.042
intracellular estrogen receptor signaling pathway GO:0030520 3 0.041
neuronal stem cell maintenance GO:0097150 2 0.041
response to bacterium GO:0009617 58 0.041
response to starvation GO:0042594 5 0.041
positive regulation of transport GO:0051050 2 0.040
response to lipid GO:0033993 60 0.040
cellular response to estrogen stimulus GO:0071391 24 0.040
locomotion GO:0040011 313 0.040
positive regulation of cellular protein metabolic process GO:0032270 22 0.040
Mouse
carbohydrate derivative biosynthetic process GO:1901137 43 0.040
endocardium morphogenesis GO:0003160 4 0.039
erythrocyte development GO:0048821 24 0.039
negative regulation of intracellular signal transduction GO:1902532 22 0.039
regulation of cellular ketone metabolic process GO:0010565 7 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.039
Mouse
gastrulation GO:0007369 208 0.039
response to abiotic stimulus GO:0009628 122 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
aging GO:0007568 2 0.038
regulation of anatomical structure morphogenesis GO:0022603 130 0.038
regulation of epithelial to mesenchymal transition GO:0010717 3 0.038
regulation of organ growth GO:0046620 3 0.038
regulation of reproductive process GO:2000241 4 0.038
regulation of protein transport GO:0051223 3 0.037
embryonic heart tube morphogenesis GO:0003143 108 0.037
response to immobilization stress GO:0035902 1 0.037
positive regulation of cell differentiation GO:0045597 30 0.037
zymogen activation GO:0031638 3 0.036
negative regulation of catalytic activity GO:0043086 21 0.036
positive regulation of secretion GO:0051047 1 0.036
positive regulation of camp biosynthetic process GO:0030819 2 0.035
cellular component biogenesis GO:0044085 178 0.035
immune system process GO:0002376 241 0.035
chordate embryonic development GO:0043009 271 0.035
Zebrafish
macromolecule modification GO:0043412 111 0.034
Mouse
response to oxygen levels GO:0070482 25 0.034
regulation of cell migration GO:0030334 40 0.034
hepaticobiliary system development GO:0061008 98 0.034
gtp metabolic process GO:0046039 4 0.033
cardiocyte differentiation GO:0035051 44 0.033
cellular response to endogenous stimulus GO:0071495 68 0.033
Mouse
lateral line development GO:0048882 66 0.033
response to metal ion GO:0010038 34 0.033
negative regulation of phosphorus metabolic process GO:0010563 13 0.033
wound healing GO:0042060 90 0.032
Zebrafish
cellular response to hormone stimulus GO:0032870 39 0.032
Mouse
rhombomere development GO:0021546 19 0.032
negative regulation of hormone secretion GO:0046888 2 0.032
carbohydrate derivative metabolic process GO:1901135 61 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.031
Mouse
cellular response to nutrient levels GO:0031669 2 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.031
positive regulation of cell death GO:0010942 29 0.031
negative regulation of dna metabolic process GO:0051053 4 0.031
regulation of organ morphogenesis GO:2000027 35 0.031
cardiac atrium morphogenesis GO:0003209 2 0.031
transmembrane transport GO:0055085 120 0.031
blood circulation GO:0008015 87 0.030
skeletal system morphogenesis GO:0048705 102 0.030
glial cell fate specification GO:0021780 4 0.030
lipid digestion GO:0044241 3 0.030
nucleotide biosynthetic process GO:0009165 21 0.030
regulation of endothelial cell differentiation GO:0045601 3 0.030
lipid biosynthetic process GO:0008610 22 0.030
positive regulation of muscle organ development GO:0048636 1 0.030
neuroblast proliferation GO:0007405 2 0.030
ventral spinal cord development GO:0021517 35 0.029
lipid storage GO:0019915 1 0.029
nitric oxide mediated signal transduction GO:0007263 2 0.029
negative regulation of protein kinase activity GO:0006469 4 0.029
response to chemical GO:0042221 320 0.028
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.028
muscle cell differentiation GO:0042692 139 0.028
Mouse
regulation of nervous system development GO:0051960 90 0.028
establishment of localization GO:0051234 244 0.028
multicellular organism reproduction GO:0032504 35 0.028
Zebrafish
lipid homeostasis GO:0055088 3 0.028
embryonic digestive tract development GO:0048566 4 0.027
regulation of intracellular signal transduction GO:1902531 57 0.027
Mouse
heart looping GO:0001947 94 0.027
embryonic heart tube development GO:0035050 133 0.027
response to steroid hormone GO:0048545 35 0.027
generation of neurons GO:0048699 385 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.026
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.026
cellular response to stress GO:0033554 62 0.026
Mouse
positive regulation of secretion by cell GO:1903532 1 0.026
response to hexose GO:0009746 3 0.026
regulation of cell activation GO:0050865 1 0.026
rhombomere 5 development GO:0021571 4 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
apoptotic process involved in morphogenesis GO:0060561 2 0.025
cation transport GO:0006812 81 0.025
cellular lipid metabolic process GO:0044255 36 0.025
Mouse
positive regulation of response to external stimulus GO:0032103 9 0.025
adult behavior GO:0030534 2 0.025
regulation of ion transmembrane transporter activity GO:0032412 2 0.025
negative regulation of stem cell differentiation GO:2000737 2 0.025
negative regulation of developmental process GO:0051093 65 0.025
amine metabolic process GO:0009308 2 0.025
cellular response to starvation GO:0009267 1 0.025
positive regulation of molecular function GO:0044093 33 0.025
Mouse
regulation of cytokine production GO:0001817 3 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.024
Mouse
myeloid cell differentiation GO:0030099 86 0.024
regulation of hormone levels GO:0010817 21 0.024
cellular component assembly GO:0022607 170 0.024
larval development GO:0002164 2 0.024
autophagy GO:0006914 4 0.024
regulation of cell development GO:0060284 100 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
regulation of developmental growth GO:0048638 38 0.023
intestinal epithelial cell differentiation GO:0060575 3 0.023
nuclear import GO:0051170 3 0.023
pyruvate metabolic process GO:0006090 1 0.023
angiogenesis GO:0001525 158 0.023
regulation of transcription involved in cell fate commitment GO:0060850 1 0.023
negative regulation of secretion by cell GO:1903531 2 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.022
apoptotic process GO:0006915 116 0.022
Mouse
endothelial cell differentiation GO:0045446 20 0.022
eye development GO:0001654 277 0.022
single organism nuclear import GO:1902593 3 0.022
hepatocyte proliferation GO:0072574 2 0.022
small molecule biosynthetic process GO:0044283 16 0.021
neuron differentiation GO:0030182 353 0.021
response to external stimulus GO:0009605 264 0.021
response to amphetamine GO:0001975 1 0.021
macromolecule localization GO:0033036 54 0.021
negative regulation of cell death GO:0060548 60 0.021
muscle structure development GO:0061061 196 0.021
Mouse
regulation of type b pancreatic cell development GO:2000074 1 0.020
embryonic digestive tract morphogenesis GO:0048557 3 0.020
cardiac cell fate commitment GO:0060911 1 0.020
multicellular organismal response to stress GO:0033555 2 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
cation homeostasis GO:0055080 33 0.020
steroid metabolic process GO:0008202 7 0.020
osteoclast differentiation GO:0030316 1 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
cellular response to oxygen containing compound GO:1901701 20 0.020
Mouse
response to peptide hormone GO:0043434 6 0.020
Mouse Rat
cell projection organization GO:0030030 284 0.019
central nervous system myelin formation GO:0032289 1 0.019
heart contraction GO:0060047 71 0.019
gtp catabolic process GO:0006184 2 0.019
hormone biosynthetic process GO:0042446 3 0.019
bmp signaling pathway GO:0030509 52 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.018
multicellular organismal macromolecule metabolic process GO:0044259 2 0.018
positive regulation of muscle tissue development GO:1901863 1 0.018
determination of intestine left right asymmetry GO:0071908 2 0.018
positive regulation of gastrulation GO:2000543 2 0.018
sensory organ morphogenesis GO:0090596 200 0.018
defense response GO:0006952 47 0.018
neuron development GO:0048666 262 0.018
developmental growth GO:0048589 166 0.018
Zebrafish
positive regulation of hydrolase activity GO:0051345 13 0.018
negative regulation of rna biosynthetic process GO:1902679 45 0.018
Mouse
anterior commissure morphogenesis GO:0021960 3 0.018
regulation of growth GO:0040008 42 0.018
regulation of anatomical structure size GO:0090066 33 0.018
neural tube development GO:0021915 62 0.017
interspecies interaction between organisms GO:0044419 4 0.017
cardiac endothelial cell differentiation GO:0003348 5 0.017
protein secretion GO:0009306 1 0.017
transcription from rna polymerase iii promoter GO:0006383 1 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
immune effector process GO:0002252 23 0.017
dorsal ventral neural tube patterning GO:0021904 1 0.017
rostrocaudal neural tube patterning GO:0021903 29 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
regulation of cell growth GO:0001558 29 0.017
segment polarity determination GO:0007367 1 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
monovalent inorganic cation homeostasis GO:0055067 9 0.017
nuclear transport GO:0051169 4 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
regulation of autophagy GO:0010506 3 0.017
organophosphate metabolic process GO:0019637 37 0.017
Mouse
protein import GO:0017038 3 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
positive regulation of protein metabolic process GO:0051247 23 0.016
Mouse
intracellular receptor signaling pathway GO:0030522 30 0.016
muscle organ development GO:0007517 101 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
neuron migration GO:0001764 22 0.016
positive regulation of cell development GO:0010720 25 0.016
positive regulation of nervous system development GO:0051962 25 0.016
maintenance of location GO:0051235 4 0.015
defense response to gram negative bacterium GO:0050829 8 0.015
cellular amine metabolic process GO:0044106 2 0.015
specification of organ identity GO:0010092 2 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of cell differentiation GO:0045596 46 0.015
vestibular receptor cell development GO:0060118 3 0.015
purine containing compound metabolic process GO:0072521 29 0.015
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.015
striated muscle cell differentiation GO:0051146 129 0.015
Mouse
regulation of blood pressure GO:0008217 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
positive regulation of chronic inflammatory response GO:0002678 1 0.015
response to estrogen GO:0043627 27 0.015
digestive tract development GO:0048565 265 0.015
regulation of protein metabolic process GO:0051246 56 0.015
Mouse
system process GO:0003008 185 0.014
positive regulation of cell activation GO:0050867 1 0.014
macromolecule catabolic process GO:0009057 15 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
digestive tract morphogenesis GO:0048546 231 0.014
epithelial cell fate commitment GO:0072148 11 0.014
phagocytosis GO:0006909 3 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
positive regulation of immune response GO:0050778 11 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
somitogenesis GO:0001756 87 0.014
Zebrafish
stem cell division GO:0017145 1 0.014
regulation of heart morphogenesis GO:2000826 17 0.014
pigment metabolic process GO:0042440 12 0.014
tissue remodeling GO:0048771 4 0.014
regulation of transport GO:0051049 45 0.014
apoptotic signaling pathway GO:0097190 23 0.014
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
ventral spinal cord interneuron differentiation GO:0021514 12 0.013
ion homeostasis GO:0050801 41 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
regulation of tube size GO:0035150 2 0.013
blood coagulation GO:0007596 12 0.013
exocrine pancreas development GO:0031017 28 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
lymphocyte proliferation GO:0046651 1 0.013
regulation of cardiac muscle cell contraction GO:0086004 1 0.013
cellular catabolic process GO:0044248 27 0.013
positive regulation of histone modification GO:0031058 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
Mouse
positive regulation of immune effector process GO:0002699 3 0.013
regulation of hydrolase activity GO:0051336 28 0.013
cellular response to steroid hormone stimulus GO:0071383 31 0.013
positive regulation of phosphate metabolic process GO:0045937 21 0.013
Mouse
endocardium development GO:0003157 9 0.013

ins disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.130
glucose metabolism disease DOID:4194 0 0.117
acquired metabolic disease DOID:0060158 0 0.117
diabetes mellitus DOID:9351 0 0.117
disease of metabolism DOID:0014667 0 0.117
type 2 diabetes mellitus DOID:9352 0 0.117
carbohydrate metabolism disease DOID:0050013 0 0.117
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017