Danio rerio

0 known processes

insl3

insulin-like 3 (Leydig cell)

(Aliases: RFLX,si:rp71-39b20.5,rlx3c,rln2,rln3c)

insl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.156
Mouse Rat
larval development GO:0002164 2 0.139
aging GO:0007568 2 0.133
organic substance biosynthetic process GO:1901576 289 0.093
biosynthetic process GO:0009058 294 0.089
adult behavior GO:0030534 2 0.083
lipid storage GO:0019915 1 0.079
cell surface receptor signaling pathway GO:0007166 325 0.075
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.074
heterocycle metabolic process GO:0046483 290 0.072
response to corticosteroid GO:0031960 1 0.071
regulation of signaling GO:0023051 235 0.068
Mouse Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.068
single organism metabolic process GO:0044710 217 0.062
cellular aromatic compound metabolic process GO:0006725 295 0.061
cellular macromolecule biosynthetic process GO:0034645 224 0.060
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
cellular ketone metabolic process GO:0042180 11 0.059
fatty acid biosynthetic process GO:0006633 4 0.058
cellular macromolecule metabolic process GO:0044260 391 0.057
female sex differentiation GO:0046660 4 0.055
female gonad development GO:0008585 4 0.051
rna metabolic process GO:0016070 219 0.051
regulation of biological quality GO:0065008 263 0.048
cellular biosynthetic process GO:0044249 286 0.047
g protein coupled receptor signaling pathway GO:0007186 74 0.047
Rat
maintenance of location GO:0051235 4 0.046
response to stress GO:0006950 263 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.045
development of primary female sexual characteristics GO:0046545 4 0.044
nitrogen compound metabolic process GO:0006807 319 0.044
gene expression GO:0010467 252 0.044
response to organic substance GO:0010033 153 0.043
nucleic acid metabolic process GO:0090304 244 0.043
response to chemical GO:0042221 320 0.042
immune system process GO:0002376 241 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
small molecule metabolic process GO:0044281 77 0.039
carboxylic acid metabolic process GO:0019752 22 0.038
amine metabolic process GO:0009308 2 0.038
lipid homeostasis GO:0055088 3 0.038
cellular response to xenobiotic stimulus GO:0071466 35 0.038
heterocycle biosynthetic process GO:0018130 215 0.037
regulation of nucleic acid templated transcription GO:1903506 213 0.037
oxoacid metabolic process GO:0043436 31 0.037
lipid catabolic process GO:0016042 4 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
regulation of transcription dna templated GO:0006355 213 0.036
regulation of cellular metabolic process GO:0031323 320 0.036
regulation of protein catabolic process GO:0042176 1 0.035
single organism localization GO:1902578 225 0.035
cellular amine metabolic process GO:0044106 2 0.034
ovulation cycle process GO:0022602 2 0.033
head development GO:0060322 303 0.033
hormone biosynthetic process GO:0042446 3 0.032
organic acid metabolic process GO:0006082 31 0.032
response to transition metal nanoparticle GO:1990267 28 0.032
cellular response to endogenous stimulus GO:0071495 68 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
rna biosynthetic process GO:0032774 181 0.031
regulation of biosynthetic process GO:0009889 250 0.030
central nervous system development GO:0007417 387 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
negative regulation of biological process GO:0048519 304 0.030
lipid metabolic process GO:0006629 52 0.029
response to carbohydrate GO:0009743 3 0.028
single organism transport GO:0044765 206 0.028
regulation of metal ion transport GO:0010959 4 0.028
regulation of response to stimulus GO:0048583 269 0.028
Mouse Rat
aromatic compound biosynthetic process GO:0019438 217 0.027
regulation of primary metabolic process GO:0080090 311 0.027
transcription dna templated GO:0006351 181 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
positive regulation of transport GO:0051050 2 0.027
organelle assembly GO:0070925 110 0.027
multicellular organism growth GO:0035264 4 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
response to nutrient GO:0007584 3 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
small molecule catabolic process GO:0044282 3 0.026
regulation of rna metabolic process GO:0051252 224 0.026
regulation of gene expression GO:0010468 265 0.026
positive regulation of catabolic process GO:0009896 4 0.026
alcohol biosynthetic process GO:0046165 2 0.026
cellular response to chemical stimulus GO:0070887 157 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
response to vitamin GO:0033273 3 0.025
generation of neurons GO:0048699 385 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
gland development GO:0048732 143 0.024
Mouse
response to glucocorticoid GO:0051384 1 0.024
regulation of developmental process GO:0050793 247 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
negative regulation of cytoplasmic transport GO:1903650 2 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
cellular lipid metabolic process GO:0044255 36 0.023
positive regulation of biological process GO:0048518 253 0.023
regulation of reactive oxygen species metabolic process GO:2000377 2 0.023
single organism organelle organization GO:1902589 199 0.023
response to hexose GO:0009746 3 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regionalization GO:0003002 274 0.022
cellular component biogenesis GO:0044085 178 0.022
stem cell maintenance GO:0019827 4 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
negative regulation of secretion GO:0051048 2 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
specification of symmetry GO:0009799 204 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
regulation of metabolic process GO:0019222 359 0.021
positive regulation of cytokine production GO:0001819 2 0.021
response to monosaccharide GO:0034284 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
transport GO:0006810 220 0.021
regulation of transporter activity GO:0032409 2 0.021
cellular protein catabolic process GO:0044257 4 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
macromolecule biosynthetic process GO:0009059 227 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
regulation of binding GO:0051098 3 0.020
multi organism process GO:0051704 134 0.020
cellular aldehyde metabolic process GO:0006081 4 0.020
response to biotic stimulus GO:0009607 97 0.020
secondary metabolic process GO:0019748 3 0.020
neurotransmitter transport GO:0006836 2 0.020
hormone secretion GO:0046879 2 0.020
negative regulation of secretion by cell GO:1903531 2 0.020
regulation of protein complex assembly GO:0043254 3 0.020
nucleic acid templated transcription GO:0097659 181 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
organic acid catabolic process GO:0016054 3 0.020
atp catabolic process GO:0006200 4 0.020
rna localization GO:0006403 4 0.019
negative regulation of protein transport GO:0051224 3 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
cell part morphogenesis GO:0032990 246 0.019
neuron projection morphogenesis GO:0048812 161 0.019
phagocytosis GO:0006909 3 0.019
cellular component assembly GO:0022607 170 0.019
negative regulation of cellular process GO:0048523 283 0.019
protein localization to nucleus GO:0034504 3 0.019
xenobiotic metabolic process GO:0006805 4 0.019
hindbrain development GO:0030902 91 0.019
regulation of cell communication GO:0010646 232 0.018
Mouse Rat
tube morphogenesis GO:0035239 349 0.018
regulation of protein transport GO:0051223 3 0.018
establishment of localization GO:0051234 244 0.018
cellular response to organic substance GO:0071310 105 0.018
protein acetylation GO:0006473 2 0.018
meiotic cell cycle process GO:1903046 3 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cellular modified amino acid metabolic process GO:0006575 3 0.018
regulation of cell activation GO:0050865 1 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
regulation of signal transduction GO:0009966 225 0.018
Mouse Rat
digestive tract morphogenesis GO:0048546 231 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of protein polymerization GO:0032271 2 0.018
brain development GO:0007420 293 0.018
establishment of protein localization to organelle GO:0072594 4 0.017
response to oxygen containing compound GO:1901700 55 0.017
glucose homeostasis GO:0042593 1 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
endocrine process GO:0050886 2 0.017
defense response GO:0006952 47 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
positive regulation of cell cycle GO:0045787 3 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
positive regulation of cellular process GO:0048522 201 0.017
response to drug GO:0042493 3 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
determination of left right symmetry GO:0007368 179 0.017
segmentation GO:0035282 97 0.017
neurotransmitter secretion GO:0007269 2 0.017
negative regulation of hormone secretion GO:0046888 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
cytokinesis GO:0000910 3 0.016
regulation of reproductive process GO:2000241 4 0.016
response to external stimulus GO:0009605 264 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
regulation of inflammatory response GO:0050727 2 0.016
protein polymerization GO:0051258 4 0.016
homeostatic process GO:0042592 142 0.016
nuclear import GO:0051170 3 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
regulation of blood pressure GO:0008217 1 0.016
tissue remodeling GO:0048771 4 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
response to endogenous stimulus GO:0009719 83 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
developmental growth GO:0048589 166 0.015
Mouse
stem cell proliferation GO:0072089 4 0.015
post embryonic organ development GO:0048569 4 0.015
response to metal ion GO:0010038 34 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.015
chemosensory behavior GO:0007635 1 0.015
protein secretion GO:0009306 1 0.015
regulation of cytokine production GO:0001817 3 0.015
atp synthesis coupled electron transport GO:0042773 1 0.015
positive regulation of secretion GO:0051047 1 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
cellular component movement GO:0006928 335 0.015
neuron development GO:0048666 262 0.014
response to methylmercury GO:0051597 11 0.014
single organism biosynthetic process GO:0044711 71 0.014
response to antibiotic GO:0046677 1 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
cell projection morphogenesis GO:0048858 244 0.014
water homeostasis GO:0030104 4 0.014
organelle organization GO:0006996 227 0.014
energy reserve metabolic process GO:0006112 2 0.014
regulation of hormone secretion GO:0046883 2 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
positive regulation of cell activation GO:0050867 1 0.014
phosphorus metabolic process GO:0006793 109 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
nuclear transport GO:0051169 4 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
embryonic organ development GO:0048568 381 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
cell projection organization GO:0030030 284 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
estrogen metabolic process GO:0008210 2 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of blood vessel size GO:0050880 2 0.014
response to glucose GO:0009749 3 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
somatic muscle development GO:0007525 4 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
muscle cell development GO:0055001 115 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
digestive system development GO:0055123 289 0.013
response to organic cyclic compound GO:0014070 51 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
intracellular mrna localization GO:0008298 1 0.013
response to cadmium ion GO:0046686 14 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
superoxide metabolic process GO:0006801 2 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
response to other organism GO:0051707 97 0.013
positive regulation of blood circulation GO:1903524 2 0.013
response to external biotic stimulus GO:0043207 97 0.013
cellular response to nutrient levels GO:0031669 2 0.012
protein acylation GO:0043543 3 0.012
innate immune response GO:0045087 13 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
endocrine hormone secretion GO:0060986 2 0.012
neuron differentiation GO:0030182 353 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of cell differentiation GO:0045595 142 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
b cell activation GO:0042113 2 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
regulation of tube size GO:0035150 2 0.012
response to bacterium GO:0009617 58 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
determination of dorsal ventral asymmetry GO:0048262 34 0.012
determination of bilateral symmetry GO:0009855 204 0.012
cellular response to starvation GO:0009267 1 0.012
cell substrate adhesion GO:0031589 4 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
programmed cell death GO:0012501 119 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
lateral inhibition GO:0046331 1 0.012
cellular protein modification process GO:0006464 100 0.012
carboxylic acid biosynthetic process GO:0046394 12 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of lipid transport GO:0032368 4 0.011
cell proliferation GO:0008283 80 0.011
catecholamine metabolic process GO:0006584 2 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
response to hormone GO:0009725 48 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
regulation of protein targeting GO:1903533 2 0.011
protein import into nucleus GO:0006606 3 0.011
sequestering of metal ion GO:0051238 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cognition GO:0050890 1 0.011
spermatid differentiation GO:0048515 2 0.011
muscle organ development GO:0007517 101 0.011
negative regulation of multi organism process GO:0043901 3 0.011
response to food GO:0032094 1 0.011
meiotic nuclear division GO:0007126 4 0.011
anterior posterior pattern specification GO:0009952 152 0.011
immune system development GO:0002520 191 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
muscle structure development GO:0061061 196 0.011
response to lipid GO:0033993 60 0.011
interaction with host GO:0051701 4 0.011
cytoplasm organization GO:0007028 4 0.011
peptide transport GO:0015833 1 0.011
single organism reproductive process GO:0044702 40 0.011
Mouse
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
cyclic purine nucleotide metabolic process GO:0052652 18 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
muscle tissue development GO:0060537 110 0.011
negative regulation of kinase activity GO:0033673 4 0.011
hemopoiesis GO:0030097 183 0.011
gtp catabolic process GO:0006184 2 0.011
calcium ion import GO:0070509 4 0.011
cell matrix adhesion GO:0007160 4 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
positive regulation of gene expression GO:0010628 71 0.010
peptidyl serine modification GO:0018209 2 0.010
compound eye development GO:0048749 2 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
exocytosis GO:0006887 1 0.010
monocarboxylic acid biosynthetic process GO:0072330 12 0.010
multicellular organismal water homeostasis GO:0050891 1 0.010
protein homooligomerization GO:0051260 3 0.010
spermatid development GO:0007286 2 0.010
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
heart development GO:0007507 313 0.010
cytoskeleton organization GO:0007010 96 0.010
cell death GO:0008219 121 0.010
actin filament polymerization GO:0030041 2 0.010
regulation of stem cell proliferation GO:0072091 2 0.010

insl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
disease of metabolism DOID:0014667 0 0.020
disease of cellular proliferation DOID:14566 0 0.014