Danio rerio

70 known processes

irak4

interleukin-1 receptor-associated kinase 4

(Aliases: zgc:55553,MGC55553)

irak4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 3 0.228
lymphocyte mediated immunity GO:0002449 5 0.212
positive regulation of immune effector process GO:0002699 3 0.210
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.195
positive regulation of cytokine production GO:0001819 2 0.176
regulation of cytokine production GO:0001817 3 0.173
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.162
positive regulation of stress activated mapk cascade GO:0032874 3 0.158
activation of immune response GO:0002253 9 0.158
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.154
regulation of cellular amino acid metabolic process GO:0006521 0 0.133
regulation of gene expression GO:0010468 265 0.130
regulation of response to stimulus GO:0048583 269 0.129
regulation of macromolecule metabolic process GO:0060255 317 0.121
regulation of cellular metabolic process GO:0031323 320 0.120
regulation of multicellular organismal process GO:0051239 277 0.118
regulation of signal transduction GO:0009966 225 0.115
immune system process GO:0002376 241 0.115
signal transduction GO:0007165 455 0.108
positive regulation of immune response GO:0050778 11 0.103
protein secretion GO:0009306 1 0.101
positive regulation of response to stimulus GO:0048584 80 0.096
cellular response to molecule of bacterial origin GO:0071219 3 0.094
myeloid leukocyte differentiation GO:0002573 15 0.094
regulation of protein transport GO:0051223 3 0.092
response to chemical GO:0042221 320 0.091
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.089
regulation of cell communication GO:0010646 232 0.087
positive regulation of jnk cascade GO:0046330 3 0.086
establishment of localization GO:0051234 244 0.082
cellular response to biotic stimulus GO:0071216 3 0.082
gene expression GO:0010467 252 0.079
tissue remodeling GO:0048771 4 0.077
immune response GO:0006955 28 0.074
immune response regulating signaling pathway GO:0002764 5 0.072
regulation of transcription dna templated GO:0006355 213 0.070
transport GO:0006810 220 0.069
production of molecular mediator of immune response GO:0002440 2 0.068
response to external stimulus GO:0009605 264 0.066
adaptive immune response GO:0002250 5 0.066
hematopoietic or lymphoid organ development GO:0048534 191 0.066
blood vessel morphogenesis GO:0048514 216 0.065
embryo development ending in birth or egg hatching GO:0009792 271 0.065
positive regulation of myeloid cell differentiation GO:0045639 2 0.063
positive regulation of leukocyte mediated immunity GO:0002705 1 0.063
regulation of signaling GO:0023051 235 0.060
regulation of production of molecular mediator of immune response GO:0002700 1 0.060
establishment of protein localization to organelle GO:0072594 4 0.056
single organism transport GO:0044765 206 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.055
i kappab kinase nf kappab signaling GO:0007249 4 0.054
positive regulation of apoptotic signaling pathway GO:2001235 1 0.054
mononuclear cell proliferation GO:0032943 1 0.054
cell projection morphogenesis GO:0048858 244 0.054
nuclear transport GO:0051169 4 0.054
protein polyubiquitination GO:0000209 4 0.053
leukocyte proliferation GO:0070661 1 0.053
intracellular signal transduction GO:0035556 85 0.053
regulation of immune response GO:0050776 14 0.053
multi organism process GO:0051704 134 0.053
nucleocytoplasmic transport GO:0006913 4 0.052
positive regulation of metabolic process GO:0009893 108 0.051
protein metabolic process GO:0019538 183 0.050
larval development GO:0002164 2 0.050
immune response activating signal transduction GO:0002757 5 0.050
cellular component assembly GO:0022607 170 0.050
protein import GO:0017038 3 0.049
cellular nitrogen compound metabolic process GO:0034641 290 0.049
regulation of leukocyte mediated immunity GO:0002703 1 0.049
myeloid cell differentiation GO:0030099 86 0.048
regulation of nucleic acid templated transcription GO:1903506 213 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.046
regulation of cellular amine metabolic process GO:0033238 0 0.046
primary neural tube formation GO:0014020 1 0.046
single organism localization GO:1902578 225 0.045
embryonic limb morphogenesis GO:0030326 2 0.045
positive regulation of biological process GO:0048518 253 0.045
regulation of response to biotic stimulus GO:0002831 2 0.045
stem cell proliferation GO:0072089 4 0.045
nuclear import GO:0051170 3 0.044
lymphocyte proliferation GO:0046651 1 0.044
peptidyl serine phosphorylation GO:0018105 1 0.044
nucleic acid metabolic process GO:0090304 244 0.044
nucleic acid templated transcription GO:0097659 181 0.043
nik nf kappab signaling GO:0038061 1 0.043
regulation of metabolic process GO:0019222 359 0.043
immune effector process GO:0002252 23 0.043
protein import into nucleus GO:0006606 3 0.043
cellular amide metabolic process GO:0043603 4 0.042
cellular ketone metabolic process GO:0042180 11 0.042
cellular macromolecule metabolic process GO:0044260 391 0.042
amine metabolic process GO:0009308 2 0.041
innate immune response GO:0045087 13 0.041
macromolecule biosynthetic process GO:0009059 227 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
modification dependent protein catabolic process GO:0019941 3 0.041
regulation of molecular function GO:0065009 70 0.040
regulation of macromolecule biosynthetic process GO:0010556 225 0.040
positive regulation of cell activation GO:0050867 1 0.039
response to virus GO:0009615 21 0.039
positive regulation of map kinase activity GO:0043406 3 0.039
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.039
regulation of immune effector process GO:0002697 5 0.039
cell part morphogenesis GO:0032990 246 0.039
regulation of immune system process GO:0002682 34 0.038
immune system development GO:0002520 191 0.038
regulation of protein complex assembly GO:0043254 3 0.038
protein targeting to nucleus GO:0044744 3 0.038
hemopoiesis GO:0030097 183 0.038
organic substance transport GO:0071702 58 0.037
regulation of response to cytokine stimulus GO:0060759 3 0.037
morphogenesis of an epithelium GO:0002009 333 0.036
chordate embryonic development GO:0043009 271 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.036
response to external biotic stimulus GO:0043207 97 0.036
regulation of protein metabolic process GO:0051246 56 0.035
extrinsic apoptotic signaling pathway GO:0097191 3 0.035
antimicrobial humoral response GO:0019730 2 0.035
response to organic substance GO:0010033 153 0.035
cellular amine metabolic process GO:0044106 2 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
regulation of response to stress GO:0080134 36 0.034
glucose import GO:0046323 2 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.032
regulation of cytokine biosynthetic process GO:0042035 1 0.032
regulation of metal ion transport GO:0010959 4 0.032
cell morphogenesis GO:0000902 289 0.032
erk1 and erk2 cascade GO:0070371 4 0.032
cellular component morphogenesis GO:0032989 336 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
regulation of biological quality GO:0065008 263 0.031
transcription dna templated GO:0006351 181 0.031
regulation of intracellular signal transduction GO:1902531 57 0.031
leukocyte mediated immunity GO:0002443 6 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
regulation of developmental process GO:0050793 247 0.031
negative regulation of protein kinase activity GO:0006469 4 0.030
peptidyl serine modification GO:0018209 2 0.030
angiogenesis GO:0001525 158 0.030
cytokinesis GO:0000910 3 0.030
stem cell maintenance GO:0019827 4 0.030
response to other organism GO:0051707 97 0.030
positive regulation of developmental process GO:0051094 50 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
cognition GO:0050890 1 0.029
positive regulation of transport GO:0051050 2 0.029
cellular component biogenesis GO:0044085 178 0.029
peptide metabolic process GO:0006518 1 0.029
cytokine metabolic process GO:0042107 1 0.029
regulation of receptor activity GO:0010469 2 0.029
response to bacterium GO:0009617 58 0.029
blood vessel development GO:0001568 246 0.029
death GO:0016265 121 0.029
regulation of biosynthetic process GO:0009889 250 0.028
growth GO:0040007 174 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
aging GO:0007568 2 0.028
single organism nuclear import GO:1902593 3 0.028
regulation of stem cell proliferation GO:0072091 2 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
regulation of erk1 and erk2 cascade GO:0070372 4 0.027
positive regulation of multi organism process GO:0043902 3 0.027
positive regulation of cell killing GO:0031343 2 0.027
macromolecular complex assembly GO:0065003 35 0.027
establishment of localization in cell GO:0051649 77 0.027
phosphorus metabolic process GO:0006793 109 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
regulation of protein ubiquitination GO:0031396 3 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
regionalization GO:0003002 274 0.026
response to biotic stimulus GO:0009607 97 0.026
somite development GO:0061053 96 0.026
viral process GO:0016032 1 0.026
positive regulation of signal transduction GO:0009967 56 0.026
regulation of rna metabolic process GO:0051252 224 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
odontogenesis of dentin containing tooth GO:0042475 1 0.025
regulation of protein targeting GO:1903533 2 0.025
regulation of organ growth GO:0046620 3 0.025
protein localization to nucleus GO:0034504 3 0.025
positive regulation of cell cycle GO:0045787 3 0.025
embryonic organ development GO:0048568 381 0.025
response to nutrient GO:0007584 3 0.025
female sex differentiation GO:0046660 4 0.025
regulation of rna biosynthetic process GO:2001141 213 0.025
cellular biosynthetic process GO:0044249 286 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
positive regulation of leukocyte differentiation GO:1902107 1 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
gtp metabolic process GO:0046039 4 0.024
heterocycle metabolic process GO:0046483 290 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
negative regulation of cellular catabolic process GO:0031330 3 0.024
neuron projection development GO:0031175 180 0.023
regulation of protein catabolic process GO:0042176 1 0.023
positive regulation of rna biosynthetic process GO:1902680 57 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
autophagy GO:0006914 4 0.023
vasculature development GO:0001944 278 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
protein complex biogenesis GO:0070271 30 0.023
multicellular organism growth GO:0035264 4 0.023
cellular protein catabolic process GO:0044257 4 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
coagulation GO:0050817 13 0.022
leukocyte differentiation GO:0002521 25 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
regulation of inflammatory response GO:0050727 2 0.022
central nervous system development GO:0007417 387 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.021
regulation of circadian sleep wake cycle GO:0042749 1 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
positive regulation of rna metabolic process GO:0051254 59 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
negative regulation of cytokine production GO:0001818 1 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
toll like receptor signaling pathway GO:0002224 4 0.021
regulation of jun kinase activity GO:0043506 3 0.021
homeostatic process GO:0042592 142 0.021
regulation of primary metabolic process GO:0080090 311 0.021
gland development GO:0048732 143 0.021
phagocytosis GO:0006909 3 0.021
regulation of jak stat cascade GO:0046425 3 0.021
t cell mediated immunity GO:0002456 1 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
protein complex assembly GO:0006461 30 0.021
oxoacid metabolic process GO:0043436 31 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
spermatid development GO:0007286 2 0.020
cell death GO:0008219 121 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
regulation of synapse assembly GO:0051963 3 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
neuron projection morphogenesis GO:0048812 161 0.020
regulation of natural killer cell mediated immunity GO:0002715 1 0.020
negative regulation of catabolic process GO:0009895 3 0.020
response to stress GO:0006950 263 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
erythrocyte differentiation GO:0030218 54 0.019
organic acid metabolic process GO:0006082 31 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
rna biosynthetic process GO:0032774 181 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
positive regulation of catabolic process GO:0009896 4 0.019
immunoglobulin production GO:0002377 1 0.019
response to molecule of bacterial origin GO:0002237 14 0.019
response to ketone GO:1901654 1 0.018
response to lipid GO:0033993 60 0.018
apoptotic process GO:0006915 116 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
negative regulation of cellular process GO:0048523 283 0.018
cellular response to external stimulus GO:0071496 2 0.018
membrane fusion GO:0061025 2 0.018
system process GO:0003008 185 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
fatty acid transport GO:0015908 1 0.018
muscle cell differentiation GO:0042692 139 0.018
segmentation GO:0035282 97 0.018
multi organism cellular process GO:0044764 2 0.018
cell killing GO:0001906 2 0.018
b cell mediated immunity GO:0019724 3 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
neuron development GO:0048666 262 0.018
bone remodeling GO:0046849 2 0.017
rna metabolic process GO:0016070 219 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
regulation of lymphocyte mediated immunity GO:0002706 1 0.017
positive regulation of cytokine biosynthetic process GO:0042108 1 0.017
fertilization GO:0009566 3 0.017
cellular response to organic substance GO:0071310 105 0.017
somatic muscle development GO:0007525 4 0.017
neurotransmitter transport GO:0006836 2 0.017
osteoclast differentiation GO:0030316 1 0.017
response to vitamin GO:0033273 3 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
leukocyte mediated cytotoxicity GO:0001909 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
single organism metabolic process GO:0044710 217 0.017
maintenance of location GO:0051235 4 0.017
cell aging GO:0007569 2 0.017
response to glucocorticoid GO:0051384 1 0.017
heart development GO:0007507 313 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
regulation of binding GO:0051098 3 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
sensory perception of pain GO:0019233 1 0.016
negative regulation of neural precursor cell proliferation GO:2000178 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
somitogenesis GO:0001756 87 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.016
biosynthetic process GO:0009058 294 0.016
exocytosis GO:0006887 1 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
gtp catabolic process GO:0006184 2 0.016
regulation of synapse organization GO:0050807 3 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
phagocytosis engulfment GO:0006911 1 0.016
protein complex subunit organization GO:0071822 46 0.016
cellular response to lipid GO:0071396 39 0.016
regulation of kinase activity GO:0043549 15 0.016
cytokine production involved in immune response GO:0002367 1 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.016
regulation of cell killing GO:0031341 2 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of defense response GO:0031347 14 0.016
programmed cell death GO:0012501 119 0.016
neuroblast proliferation GO:0007405 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
cellular localization GO:0051641 97 0.015
tube closure GO:0060606 1 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of wound healing GO:0061041 2 0.015
ossification GO:0001503 23 0.015
b cell activation GO:0042113 2 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
response to hexose GO:0009746 3 0.015
axonogenesis GO:0007409 152 0.015
anatomical structure homeostasis GO:0060249 36 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
spinal cord development GO:0021510 46 0.015
response to monosaccharide GO:0034284 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of translational initiation GO:0006446 1 0.015
determination of bilateral symmetry GO:0009855 204 0.015
tube morphogenesis GO:0035239 349 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
regulation of circadian rhythm GO:0042752 4 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
cellular response to stress GO:0033554 62 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of dendrite development GO:0050773 3 0.014
germ line stem cell maintenance GO:0030718 2 0.014
cell substrate adhesion GO:0031589 4 0.014
small molecule metabolic process GO:0044281 77 0.014
response to glucose GO:0009749 3 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.014
cell projection organization GO:0030030 284 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
signal transduction by phosphorylation GO:0023014 18 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
p38mapk cascade GO:0038066 1 0.014
ion transport GO:0006811 114 0.014
modulation by virus of host morphology or physiology GO:0019048 1 0.014
long chain fatty acid transport GO:0015909 1 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of mapk cascade GO:0043408 14 0.013
cytokine mediated signaling pathway GO:0019221 7 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
liver development GO:0001889 96 0.013
activation of mapk activity GO:0000187 3 0.013
cell proliferation GO:0008283 80 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
negative regulation of defense response GO:0031348 2 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
membrane invagination GO:0010324 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
regulation of transporter activity GO:0032409 2 0.013
sleep GO:0030431 1 0.013
positive regulation of molecular function GO:0044093 33 0.013
alcohol biosynthetic process GO:0046165 2 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
protein activation cascade GO:0072376 6 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
regulation of response to oxidative stress GO:1902882 2 0.013
regulation of catalytic activity GO:0050790 55 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
camera type eye development GO:0043010 222 0.012
cytokine production GO:0001816 4 0.012
protein autoubiquitination GO:0051865 3 0.012
axon development GO:0061564 166 0.012
single organism membrane fusion GO:0044801 2 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
lymph vessel morphogenesis GO:0036303 25 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
regulation of cell activation GO:0050865 1 0.012
organelle organization GO:0006996 227 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
sex determination GO:0007530 1 0.012
hatching GO:0035188 4 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
chloride transmembrane transport GO:1902476 4 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
positive regulation of protein kinase b signaling GO:0051897 1 0.012
lipid storage GO:0019915 1 0.012
modification by symbiont of host morphology or physiology GO:0044003 4 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
neurotransmitter secretion GO:0007269 2 0.012
erythrocyte homeostasis GO:0034101 55 0.012
blood coagulation GO:0007596 12 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
positive regulation of secretion GO:0051047 1 0.012
glial cell migration GO:0008347 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 6 0.012
response to corticosteroid GO:0031960 1 0.012
embryonic organ morphogenesis GO:0048562 274 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
actomyosin structure organization GO:0031032 53 0.011
type i interferon production GO:0032606 2 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
negative regulation of signaling GO:0023057 96 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
organelle assembly GO:0070925 110 0.011
single fertilization GO:0007338 3 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
adherens junction organization GO:0034332 4 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
embryonic hemopoiesis GO:0035162 53 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
thrombocyte differentiation GO:0002574 4 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
endosomal transport GO:0016197 2 0.011
positive regulation of cell communication GO:0010647 56 0.011
response to drug GO:0042493 3 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
renal tubule morphogenesis GO:0061333 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of p38mapk cascade GO:1900744 1 0.011
taxis GO:0042330 109 0.011
positive regulation of cell substrate adhesion GO:0010811 1 0.011
organ regeneration GO:0031100 1 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
regulation of mitochondrion organization GO:0010821 1 0.011
homeostasis of number of cells GO:0048872 62 0.011
negative regulation of metabolic process GO:0009892 86 0.011
circadian sleep wake cycle GO:0042745 2 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
locomotion GO:0040011 313 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of phosphate metabolic process GO:0019220 43 0.010
single organism reproductive process GO:0044702 40 0.010
meiotic cell cycle process GO:1903046 3 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
ion transmembrane transport GO:0034220 91 0.010
cellular response to starvation GO:0009267 1 0.010

irak4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.043
disease of anatomical entity DOID:7 0 0.030
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
nervous system disease DOID:863 0 0.013
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
inherited metabolic disorder DOID:655 0 0.011