Danio rerio

0 known processes

irf7

interferon regulatory factor 7

(Aliases: wu:fl24c03,zgc:66043,MGC66043,zgc:77947)

irf7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.111
Zebrafish
regulation of signaling GO:0023051 235 0.097
Mouse
nitrogen compound metabolic process GO:0006807 319 0.086
Human Mouse
regulation of gene expression GO:0010468 265 0.077
Human Mouse
cellular macromolecule metabolic process GO:0044260 391 0.074
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.070
Human Mouse
regulation of cell communication GO:0010646 232 0.065
Mouse
signal transduction GO:0007165 455 0.064
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.063
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.059
Human Mouse
positive regulation of catabolic process GO:0009896 4 0.058
larval development GO:0002164 2 0.051
cellular aromatic compound metabolic process GO:0006725 295 0.051
Human Mouse
heterocycle metabolic process GO:0046483 290 0.049
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.048
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.047
Human Mouse
response to stress GO:0006950 263 0.045
Mouse
regulation of signal transduction GO:0009966 225 0.044
Mouse
positive regulation of biological process GO:0048518 253 0.043
Human Mouse
positive regulation of cellular process GO:0048522 201 0.043
Human Mouse
negative regulation of cellular process GO:0048523 283 0.043
response to organic substance GO:0010033 153 0.041
Mouse
aging GO:0007568 2 0.041
response to abiotic stimulus GO:0009628 122 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.040
positive regulation of cellular catabolic process GO:0031331 3 0.040
biosynthetic process GO:0009058 294 0.039
Human Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.039
regulation of rna metabolic process GO:0051252 224 0.038
Human Mouse
cellular response to dsrna GO:0071359 1 0.038
protein localization to nucleus GO:0034504 3 0.038
regulation of metal ion transport GO:0010959 4 0.038
small molecule metabolic process GO:0044281 77 0.037
negative regulation of biological process GO:0048519 304 0.037
organic acid metabolic process GO:0006082 31 0.037
cellular amino acid metabolic process GO:0006520 7 0.037
tyrosine phosphorylation of stat protein GO:0007260 1 0.035
positive regulation of cell cycle GO:0045787 3 0.035
tube morphogenesis GO:0035239 349 0.034
purine nucleoside monophosphate catabolic process GO:0009128 4 0.033
regulation of primary metabolic process GO:0080090 311 0.033
Human Mouse
aromatic compound biosynthetic process GO:0019438 217 0.032
Human Mouse
rna metabolic process GO:0016070 219 0.032
Human Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.032
response to chemical GO:0042221 320 0.032
Mouse
regulation of ion transmembrane transporter activity GO:0032412 2 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
Human Mouse
regulation of cytokine production GO:0001817 3 0.031
Human
gene expression GO:0010467 252 0.031
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.031
positive regulation of protein complex assembly GO:0031334 2 0.030
regulation of protein complex assembly GO:0043254 3 0.029
amine metabolic process GO:0009308 2 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
Mouse
negative regulation of protein localization to nucleus GO:1900181 2 0.029
determination of bilateral symmetry GO:0009855 204 0.029
multicellular organism growth GO:0035264 4 0.028
single organism metabolic process GO:0044710 217 0.028
carboxylic acid metabolic process GO:0019752 22 0.028
response to drug GO:0042493 3 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
regulation of stem cell differentiation GO:2000736 4 0.028
regulation of protein catabolic process GO:0042176 1 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
regulation of response to stimulus GO:0048583 269 0.028
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.028
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
neurotransmitter secretion GO:0007269 2 0.027
regulation of reproductive process GO:2000241 4 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
Human Mouse
regulation of protein localization to nucleus GO:1900180 2 0.027
positive regulation of metabolic process GO:0009893 108 0.027
Human
regulation of cellular amine metabolic process GO:0033238 0 0.027
lipid storage GO:0019915 1 0.027
transport GO:0006810 220 0.026
establishment of localization GO:0051234 244 0.026
mitochondrion organization GO:0007005 4 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
Human Mouse
regulation of transcription dna templated GO:0006355 213 0.026
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.026
Human Mouse
response to other organism GO:0051707 97 0.026
regulation of jak stat cascade GO:0046425 3 0.025
regulation of filopodium assembly GO:0051489 2 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
atp catabolic process GO:0006200 4 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.024
Human Mouse
cellular component morphogenesis GO:0032989 336 0.024
cellular ketone metabolic process GO:0042180 11 0.024
regulation of multicellular organism growth GO:0040014 4 0.023
interspecies interaction between organisms GO:0044419 4 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.023
negative regulation of metabolic process GO:0009892 86 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
intracellular signal transduction GO:0035556 85 0.023
cell cycle g2 m phase transition GO:0044839 4 0.023
protein metabolic process GO:0019538 183 0.023
Mouse
heart development GO:0007507 313 0.022
cytokinesis GO:0000910 3 0.022
organic substance biosynthetic process GO:1901576 289 0.022
Human Mouse
cellular response to retinoic acid GO:0071300 1 0.022
multi organism cellular process GO:0044764 2 0.022
regionalization GO:0003002 274 0.022
regulation of metabolic process GO:0019222 359 0.022
Human Mouse
response to external biotic stimulus GO:0043207 97 0.022
death GO:0016265 121 0.022
transcription dna templated GO:0006351 181 0.022
Human Mouse
positive regulation of response to stimulus GO:0048584 80 0.022
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.022
segmentation GO:0035282 97 0.021
cellular amine metabolic process GO:0044106 2 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
Human Mouse
female sex differentiation GO:0046660 4 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of developmental process GO:0050793 247 0.021
tissue remodeling GO:0048771 4 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
endosomal transport GO:0016197 2 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
gtp metabolic process GO:0046039 4 0.020
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
Human Mouse
cell projection organization GO:0030030 284 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
centrosome organization GO:0051297 1 0.020
regulation of calcium ion transport GO:0051924 2 0.020
phosphate containing compound metabolic process GO:0006796 108 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
Human Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
gtp catabolic process GO:0006184 2 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
Human Mouse
cellular protein metabolic process GO:0044267 129 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
meiotic nuclear division GO:0007126 4 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
specification of symmetry GO:0009799 204 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
microtubule organizing center organization GO:0031023 1 0.019
phosphorus metabolic process GO:0006793 109 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
regulation of muscle contraction GO:0006937 3 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
Human Mouse
generation of neurons GO:0048699 385 0.018
cellular component disassembly GO:0022411 1 0.018
p38mapk cascade GO:0038066 1 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
Human
proteasomal protein catabolic process GO:0010498 2 0.018
protein import GO:0017038 3 0.018
viral process GO:0016032 1 0.018
protein targeting to nucleus GO:0044744 3 0.018
neuron differentiation GO:0030182 353 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
protein import into nucleus GO:0006606 3 0.017
cell projection morphogenesis GO:0048858 244 0.017
maintenance of location GO:0051235 4 0.017
negative regulation of dna metabolic process GO:0051053 4 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
regulation of protein transport GO:0051223 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
cytoplasm organization GO:0007028 4 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
Human Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.017
positive regulation of cell communication GO:0010647 56 0.017
Mouse
determination of left right symmetry GO:0007368 179 0.017
response to amino acid GO:0043200 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
anterior posterior pattern specification GO:0009952 152 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of programmed cell death GO:0043067 101 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
alpha amino acid metabolic process GO:1901605 3 0.016
single organism nuclear import GO:1902593 3 0.016
protein polymerization GO:0051258 4 0.016
nuclear transport GO:0051169 4 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
sensory organ morphogenesis GO:0090596 200 0.016
female gonad development GO:0008585 4 0.016
regulation of cell activation GO:0050865 1 0.015
autophagy GO:0006914 4 0.015
response to superoxide GO:0000303 2 0.015
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.015
phagocytosis GO:0006909 3 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
Human Mouse
regulation of transporter activity GO:0032409 2 0.015
interaction with host GO:0051701 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
Human Mouse
brain development GO:0007420 293 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of synapse organization GO:0050807 3 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
fertilization GO:0009566 3 0.015
sensory organ development GO:0007423 393 0.015
response to biotic stimulus GO:0009607 97 0.015
peptidyl serine modification GO:0018209 2 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
Human Mouse
cellular response to stress GO:0033554 62 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.014
compound eye development GO:0048749 2 0.014
actin filament based movement GO:0030048 1 0.014
single organism membrane fusion GO:0044801 2 0.014
apoptotic process GO:0006915 116 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
response to antibiotic GO:0046677 1 0.014
cell morphogenesis GO:0000902 289 0.014
multi organism process GO:0051704 134 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
lipid homeostasis GO:0055088 3 0.014
double strand break repair GO:0006302 3 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
macromolecule modification GO:0043412 111 0.014
cell death GO:0008219 121 0.014
single organism transport GO:0044765 206 0.014
positive regulation of signal transduction GO:0009967 56 0.014
Mouse
positive regulation of cytoskeleton organization GO:0051495 3 0.014
response to lipid GO:0033993 60 0.014
rna biosynthetic process GO:0032774 181 0.014
Human Mouse
lymphocyte proliferation GO:0046651 1 0.014
skeletal system development GO:0001501 181 0.014
Zebrafish
neuron projection development GO:0031175 180 0.014
phosphorylation GO:0016310 69 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
mononuclear cell proliferation GO:0032943 1 0.014
centrosome cycle GO:0007098 1 0.014
regulation of sodium ion transport GO:0002028 2 0.014
regulation of gtpase activity GO:0043087 2 0.013
positive regulation of transport GO:0051050 2 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
Mouse
endoplasmic reticulum unfolded protein response GO:0030968 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
regulation of blood pressure GO:0008217 1 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
regulation of synapse assembly GO:0051963 3 0.013
hormone secretion GO:0046879 2 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
organelle organization GO:0006996 227 0.013
negative regulation of cell communication GO:0010648 96 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
regulation of myotube differentiation GO:0010830 2 0.013
response to hydrogen peroxide GO:0042542 3 0.013
cation transmembrane transport GO:0098655 65 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
embryonic skeletal system development GO:0048706 97 0.013
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
vacuolar transport GO:0007034 2 0.013
cellular response to nutrient levels GO:0031669 2 0.013
leukocyte mediated cytotoxicity GO:0001909 1 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
Zebrafish
calcium ion transport into cytosol GO:0060402 3 0.013
muscle cell development GO:0055001 115 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
Human
membrane invagination GO:0010324 1 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
regulation of cell differentiation GO:0045595 142 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
synaptic vesicle localization GO:0097479 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
negative regulation of reproductive process GO:2000242 3 0.012
response to hormone GO:0009725 48 0.012
stem cell proliferation GO:0072089 4 0.012
cellular response to starvation GO:0009267 1 0.012
negative regulation of signaling GO:0023057 96 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
Mouse
somite development GO:0061053 96 0.012
er nucleus signaling pathway GO:0006984 2 0.012
single fertilization GO:0007338 3 0.012
cellular protein modification process GO:0006464 100 0.012
organelle fusion GO:0048284 3 0.012
somitogenesis GO:0001756 87 0.012
regulation of protein targeting GO:1903533 2 0.012
lipid catabolic process GO:0016042 4 0.012
rna localization GO:0006403 4 0.012
b cell activation GO:0042113 2 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
homeostatic process GO:0042592 142 0.012
regulation of cell shape GO:0008360 1 0.012
cellular response to organic substance GO:0071310 105 0.012
Mouse
meiotic cell cycle process GO:1903046 3 0.012
directional locomotion GO:0033058 1 0.012
regulation of biological quality GO:0065008 263 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
programmed cell death GO:0012501 119 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
negative regulation of nuclear division GO:0051784 3 0.012
system process GO:0003008 185 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
mitochondrial transport GO:0006839 2 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
negative regulation of synapse assembly GO:0051964 2 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of intracellular ph GO:0051453 1 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
developmental programmed cell death GO:0010623 4 0.011
camera type eye development GO:0043010 222 0.011
ovulation cycle GO:0042698 2 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
hemopoiesis GO:0030097 183 0.011
positive regulation of signaling GO:0023056 56 0.011
Mouse
negative regulation of protein transport GO:0051224 3 0.011
regulation of endocrine process GO:0044060 2 0.011
cell cell recognition GO:0009988 1 0.011
protein dephosphorylation GO:0006470 3 0.011
regulation of protein polymerization GO:0032271 2 0.011
neuron development GO:0048666 262 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
iron ion homeostasis GO:0055072 4 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
Zebrafish
neurotransmitter transport GO:0006836 2 0.011
response to glucocorticoid GO:0051384 1 0.011
positive regulation of secretion GO:0051047 1 0.011
apoptotic process involved in development GO:1902742 2 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
meiotic chromosome segregation GO:0045132 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
glucose homeostasis GO:0042593 1 0.011
response to unfolded protein GO:0006986 2 0.011
head development GO:0060322 303 0.011
regulation of cell projection assembly GO:0060491 4 0.011
antimicrobial humoral response GO:0019730 2 0.011
cellular component movement GO:0006928 335 0.011
cellular respiration GO:0045333 3 0.011
regulation of p38mapk cascade GO:1900744 1 0.011
cell substrate adhesion GO:0031589 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
defense response GO:0006952 47 0.011
Mouse
determination of heart left right asymmetry GO:0061371 117 0.011
regulation of cell killing GO:0031341 2 0.011
response to topologically incorrect protein GO:0035966 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
immune system development GO:0002520 191 0.011
cellular response to oxygen levels GO:0071453 1 0.011
response to cadmium ion GO:0046686 14 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
response to wounding GO:0009611 116 0.010
nuclear import GO:0051170 3 0.010
regulation of cell death GO:0010941 103 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
cytoskeleton organization GO:0007010 96 0.010
heart process GO:0003015 71 0.010
cell cycle arrest GO:0007050 1 0.010
positive regulation of reproductive process GO:2000243 2 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
cell part morphogenesis GO:0032990 246 0.010
cell killing GO:0001906 2 0.010
peptide transport GO:0015833 1 0.010
response to alkaloid GO:0043279 2 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
cellular component assembly GO:0022607 170 0.010
membrane fusion GO:0061025 2 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
response to nutrient GO:0007584 3 0.010
calcium mediated signaling GO:0019722 2 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
positive regulation of cell killing GO:0031343 2 0.010
muscle tissue development GO:0060537 110 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
secondary metabolic process GO:0019748 3 0.010
cellular response to radiation GO:0071478 4 0.010
nuclear export GO:0051168 1 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
actin filament polymerization GO:0030041 2 0.010
cation transport GO:0006812 81 0.010
locomotor rhythm GO:0045475 3 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010

irf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.026
cardiovascular system disease DOID:1287 0 0.020
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.012
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
inherited metabolic disorder DOID:655 0 0.011
disease of metabolism DOID:0014667 0 0.011
immune system disease DOID:2914 0 0.010