Danio rerio

100 known processes

isl1

islet1

(Aliases: islet-1,Isl-1)

isl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pancreatic a cell development GO:0003322 2 1.000
peripheral nervous system neuron differentiation GO:0048934 28 0.996
embryonic organ development GO:0048568 381 0.994
Zebrafish
neuron fate determination GO:0048664 2 0.994
generation of neurons GO:0048699 385 0.991
endocardium formation GO:0060214 1 0.988
regulation of developmental process GO:0050793 247 0.986
Mouse
camera type eye morphogenesis GO:0048593 108 0.986
Zebrafish
neuron differentiation GO:0030182 353 0.983
heart development GO:0007507 313 0.983
central nervous system development GO:0007417 387 0.983
auditory receptor cell fate determination GO:0042668 2 0.981
forebrain neuron development GO:0021884 7 0.978
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.976
Human Mouse Rat Fly
nitrogen compound metabolic process GO:0006807 319 0.974
Human Mouse Rat Fly
ventral spinal cord interneuron fate commitment GO:0060579 3 0.966
regulation of transcription dna templated GO:0006355 213 0.965
Human Mouse Rat Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.958
Zebrafish Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.955
oligodendrocyte cell fate specification GO:0021778 4 0.954
nucleobase containing compound metabolic process GO:0006139 274 0.954
Human Mouse Rat Fly
positive regulation of cellular process GO:0048522 201 0.953
Human Mouse Rat Fly
inner ear receptor cell differentiation GO:0060113 29 0.952
Zebrafish
eye development GO:0001654 277 0.951
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.950
Human Mouse Rat Fly
hair cell differentiation GO:0035315 32 0.949
Zebrafish
larval development GO:0002164 2 0.948
Worm
camera type eye development GO:0043010 222 0.947
Zebrafish
pancreas development GO:0031016 84 0.947
positive regulation of biological process GO:0048518 253 0.943
Human Mouse Rat Fly
auditory receptor cell fate commitment GO:0009912 4 0.943
regulation of rna metabolic process GO:0051252 224 0.942
Human Mouse Rat Fly
cellular aromatic compound metabolic process GO:0006725 295 0.942
Human Mouse Rat Fly
retina morphogenesis in camera type eye GO:0060042 79 0.939
forebrain development GO:0030900 96 0.939
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.936
Human Mouse Rat Fly
signal transduction GO:0007165 455 0.934
Mouse Rat Fly
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.929
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.928
Human Mouse Rat Fly
photoreceptor cell fate specification GO:0043704 1 0.925
cellular macromolecule biosynthetic process GO:0034645 224 0.920
Human Mouse Rat Fly
gene expression GO:0010467 252 0.913
Human Zebrafish Mouse Rat Fly
macromolecule biosynthetic process GO:0009059 227 0.911
Human Mouse Rat Fly
mechanoreceptor differentiation GO:0042490 37 0.906
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.903
Human Mouse Rat Fly
cardiac chamber formation GO:0003207 4 0.902
positive regulation of gene expression GO:0010628 71 0.900
Human Mouse Rat Fly
embryonic heart tube development GO:0035050 133 0.895
neuromast development GO:0048884 46 0.892
cardiac muscle tissue development GO:0048738 48 0.891
regulation of inner ear receptor cell differentiation GO:2000980 1 0.884
nucleic acid metabolic process GO:0090304 244 0.884
Human Mouse Rat Fly
eye morphogenesis GO:0048592 144 0.880
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.870
Human Mouse Rat Fly
erythrocyte differentiation GO:0030218 54 0.869
enteroendocrine cell differentiation GO:0035883 9 0.869
cell morphogenesis GO:0000902 289 0.868
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.866
heart morphogenesis GO:0003007 156 0.865
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.864
Human Mouse Rat Fly
inner ear receptor cell fate commitment GO:0060120 4 0.857
regulation of neurogenesis GO:0050767 87 0.856
Mouse
neural tube development GO:0021915 62 0.846
Zebrafish
spinal cord development GO:0021510 46 0.837
rna biosynthetic process GO:0032774 181 0.836
Human Mouse Rat Fly
nerve development GO:0021675 45 0.831
Zebrafish Mouse
regulation of multicellular organismal process GO:0051239 277 0.829
pancreatic d cell differentiation GO:0003311 2 0.819
cardiac chamber development GO:0003205 19 0.816
Mouse
regulation of multicellular organismal development GO:2000026 223 0.815
Mouse
regulation of metabolic process GO:0019222 359 0.814
Human Zebrafish Mouse Rat Fly
determination of intestine left right asymmetry GO:0071908 2 0.809
negative regulation of gene expression GO:0010629 65 0.804
Mouse
vasculogenesis GO:0001570 41 0.797
digestive tract development GO:0048565 265 0.790
Worm
head development GO:0060322 303 0.789
Zebrafish Mouse Worm
spinal cord motor neuron differentiation GO:0021522 26 0.788
retina development in camera type eye GO:0060041 146 0.778
Zebrafish
photoreceptor cell fate commitment GO:0046552 1 0.774
glandular epithelial cell differentiation GO:0002067 9 0.772
regulation of nitrogen compound metabolic process GO:0051171 251 0.768
Human Mouse Rat Fly
axon development GO:0061564 166 0.766
endocrine pancreas development GO:0031018 27 0.755
vasculature development GO:0001944 278 0.751
Mouse
negative regulation of cellular process GO:0048523 283 0.749
Mouse Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.741
Human Mouse Rat Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.736
heterocycle biosynthetic process GO:0018130 215 0.729
Human Mouse Rat Fly
cardiogenic plate morphogenesis GO:0003142 1 0.716
positive regulation of neuron migration GO:2001224 2 0.714
axon extension GO:0048675 45 0.713
cellular nitrogen compound metabolic process GO:0034641 290 0.713
Human Mouse Rat Fly
chordate embryonic development GO:0043009 271 0.710
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.705
Zebrafish
peripheral nervous system neuron development GO:0048935 22 0.700
retina layer formation GO:0010842 24 0.699
regulation of glial cell differentiation GO:0045685 4 0.690
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.686
Mouse
ventral spinal cord interneuron differentiation GO:0021514 12 0.676
ventral spinal cord development GO:0021517 35 0.674
nucleic acid templated transcription GO:0097659 181 0.673
Human Mouse Rat Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.669
aromatic compound biosynthetic process GO:0019438 217 0.669
Human Mouse Rat Fly
embryonic camera type eye development GO:0031076 29 0.668
Zebrafish
neuron fate commitment GO:0048663 26 0.665
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.657
Zebrafish
regulation of neuron migration GO:2001222 2 0.656
positive regulation of nervous system development GO:0051962 25 0.650
olfactory bulb development GO:0021772 4 0.641
transcription from rna polymerase ii promoter GO:0006366 80 0.629
Human Mouse Rat Fly
hormone transport GO:0009914 2 0.626
Rat
embryonic hemopoiesis GO:0035162 53 0.615
definitive hemopoiesis GO:0060216 18 0.611
myeloid cell homeostasis GO:0002262 56 0.607
glial cell fate specification GO:0021780 4 0.602
embryonic heart tube formation GO:0003144 1 0.602
regulation of gene expression GO:0010468 265 0.601
Human Zebrafish Mouse Rat Fly
central nervous system neuron differentiation GO:0021953 74 0.601
muscle tissue development GO:0060537 110 0.594
cell differentiation in spinal cord GO:0021515 40 0.589
epithelial cell development GO:0002064 42 0.587
positive regulation of rna biosynthetic process GO:1902680 57 0.586
Human Mouse Rat Fly
inner ear morphogenesis GO:0042472 63 0.583
Zebrafish
digestive system development GO:0055123 289 0.581
forebrain dorsal ventral pattern formation GO:0021798 1 0.579
transcription dna templated GO:0006351 181 0.575
Human Mouse Rat Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.569
Human Mouse Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.567
Human Mouse Rat Fly
endocrine system development GO:0035270 65 0.566
photoreceptor cell differentiation GO:0046530 55 0.565
endocardium morphogenesis GO:0003160 4 0.562
neuron development GO:0048666 262 0.559
otolith development GO:0048840 32 0.559
Zebrafish
heterocycle metabolic process GO:0046483 290 0.555
Human Mouse Rat Fly
olfactory lobe development GO:0021988 4 0.555
neural retina development GO:0003407 49 0.553
sympathetic nervous system development GO:0048485 3 0.549
forebrain anterior posterior pattern specification GO:0021797 3 0.547
central nervous system myelination GO:0022010 2 0.546
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.545
Human Mouse Rat Fly
growth GO:0040007 174 0.541
artery development GO:0060840 22 0.540
regulation of biosynthetic process GO:0009889 250 0.535
Human Mouse Rat Fly
pancreatic a cell differentiation GO:0003310 6 0.531
type b pancreatic cell development GO:0003323 4 0.529
regulation of cell development GO:0060284 100 0.526
Mouse
lateral line development GO:0048882 66 0.516
epithelial cell differentiation GO:0030855 116 0.496
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.492
embryonic heart tube morphogenesis GO:0003143 108 0.491
neuromast hair cell differentiation GO:0048886 12 0.486
regulation of oligodendrocyte differentiation GO:0048713 1 0.483
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.482
somatic motor neuron differentiation GO:0021523 5 0.481
hindbrain morphogenesis GO:0021575 22 0.471
sensory organ development GO:0007423 393 0.470
Zebrafish Fly
diencephalon development GO:0021536 58 0.467
Zebrafish Mouse
neuron migration GO:0001764 22 0.460
compound eye development GO:0048749 2 0.459
neuromast hair cell development GO:0035675 6 0.457
morphogenesis of embryonic epithelium GO:0016331 30 0.456
Zebrafish Fly
tube morphogenesis GO:0035239 349 0.451
Zebrafish
olfactory placode development GO:0071698 12 0.446
biosynthetic process GO:0009058 294 0.445
Human Mouse Rat Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.445
Human Mouse Rat Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.444
septum transversum development GO:0003343 4 0.426
sensory organ morphogenesis GO:0090596 200 0.421
Zebrafish
photoreceptor cell development GO:0042461 40 0.420
cell fate commitment GO:0045165 99 0.419
cardiac chamber morphogenesis GO:0003206 12 0.416
Mouse
primitive hemopoiesis GO:0060215 27 0.416
positive regulation of epithelial cell differentiation GO:0030858 2 0.411
central nervous system neuron development GO:0021954 29 0.411
mechanosensory lateral line system development GO:0048881 49 0.406
response to chemical GO:0042221 320 0.401
Zebrafish Mouse Rat Fly
neuron projection development GO:0031175 180 0.400
posterior lateral line system development GO:0048915 46 0.398
artery morphogenesis GO:0048844 14 0.397
epithelial tube morphogenesis GO:0060562 148 0.380
homeostatic process GO:0042592 142 0.378
Fly
organelle assembly GO:0070925 110 0.364
regulation of nervous system development GO:0051960 90 0.361
Mouse
brain development GO:0007420 293 0.359
Zebrafish Mouse
hematopoietic stem cell differentiation GO:0060218 20 0.357
atrioventricular valve formation GO:0003190 3 0.356
aorta development GO:0035904 4 0.355
axonogenesis GO:0007409 152 0.351
positive regulation of nucleic acid templated transcription GO:1903508 57 0.350
Human Mouse Rat Fly
abducens nucleus development GO:0021742 2 0.350
hepatocyte differentiation GO:0070365 1 0.347
system process GO:0003008 185 0.341
heart looping GO:0001947 94 0.340
rna metabolic process GO:0016070 219 0.337
Human Mouse Rat Fly
eye photoreceptor cell development GO:0042462 30 0.336
specification of symmetry GO:0009799 204 0.336
regulation of nucleic acid templated transcription GO:1903506 213 0.328
Human Mouse Rat Fly
epithelial cell fate commitment GO:0072148 11 0.328
homeostasis of number of cells GO:0048872 62 0.327
positive regulation of cellular biosynthetic process GO:0031328 68 0.320
Human Mouse Rat Fly
oligodendrocyte differentiation GO:0048709 23 0.316
hematopoietic progenitor cell differentiation GO:0002244 23 0.314
camera type eye photoreceptor cell differentiation GO:0060219 19 0.313
locomotion GO:0040011 313 0.312
Zebrafish Mouse Worm Fly
mesoderm formation GO:0001707 43 0.312
positive regulation of rna metabolic process GO:0051254 59 0.312
Human Mouse Rat Fly
formation of primary germ layer GO:0001704 62 0.311
nucleobase containing compound biosynthetic process GO:0034654 205 0.309
Human Mouse Rat Fly
hemopoiesis GO:0030097 183 0.306
iris morphogenesis GO:0061072 1 0.306
swimming behavior GO:0036269 8 0.305
anterior lateral line nerve development GO:0048909 4 0.304
gliogenesis GO:0042063 45 0.304
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.300
Human Mouse Rat Fly
appendage morphogenesis GO:0035107 56 0.299
mesodermal cell differentiation GO:0048333 21 0.299
cardiac muscle cell differentiation GO:0055007 30 0.299
pectoral fin development GO:0033339 50 0.297
forebrain neuron fate commitment GO:0021877 1 0.290
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.290
outflow tract morphogenesis GO:0003151 1 0.284
Mouse
organic substance biosynthetic process GO:1901576 289 0.283
Human Mouse Rat Fly
innervation GO:0060384 3 0.283
Mouse
cell part morphogenesis GO:0032990 246 0.277
proepicardium development GO:0003342 4 0.275
hindbrain development GO:0030902 91 0.272
Zebrafish
negative regulation of nervous system development GO:0051961 22 0.271
Mouse
determination of digestive tract left right asymmetry GO:0071907 10 0.271
organelle organization GO:0006996 227 0.269
pectoral fin morphogenesis GO:0035138 29 0.269
posterior lateral line development GO:0048916 38 0.264
negative regulation of cell differentiation GO:0045596 46 0.259
Mouse
spinal cord dorsal ventral patterning GO:0021513 5 0.257
positive regulation of neuron differentiation GO:0045666 12 0.257
neuron projection guidance GO:0097485 86 0.256
Zebrafish Mouse Fly
inner ear receptor cell development GO:0060119 20 0.256
Zebrafish
auditory receptor cell differentiation GO:0042491 15 0.253
Zebrafish
negative regulation of rna metabolic process GO:0051253 48 0.251
Mouse
cell fate specification GO:0001708 68 0.251
pronephros development GO:0048793 69 0.250
Zebrafish
otolith morphogenesis GO:0032474 8 0.247
Zebrafish
pharyngeal muscle development GO:0043282 4 0.244
cellular response to drug GO:0035690 1 0.242
regionalization GO:0003002 274 0.239
Human Zebrafish Fly
tube formation GO:0035148 25 0.233
negative regulation of developmental process GO:0051093 65 0.228
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.225
forebrain midbrain boundary formation GO:0021905 1 0.225
glucose homeostasis GO:0042593 1 0.224
striated muscle cell development GO:0055002 108 0.223
cell cycle process GO:0022402 53 0.222
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.221
Mouse
regulation of cellular component organization GO:0051128 86 0.220
posterior lateral line nerve development GO:0048918 8 0.220
sensory system development GO:0048880 76 0.219
Mouse
neuron fate specification GO:0048665 20 0.216
cellular macromolecule metabolic process GO:0044260 391 0.215
Human Mouse Rat Fly
posterior lateral line neuromast development GO:0048919 20 0.214
regulation of anatomical structure morphogenesis GO:0022603 130 0.214
Mouse
patterning of lymph vessels GO:0060854 1 0.209
ventral spinal cord interneuron specification GO:0021521 3 0.209
carbohydrate homeostasis GO:0033500 1 0.206
hemangioblast cell differentiation GO:0060217 5 0.204
developmental growth involved in morphogenesis GO:0060560 86 0.200
glial cell development GO:0021782 20 0.198
appendage development GO:0048736 80 0.198
telencephalon development GO:0021537 14 0.196
Zebrafish
sprouting angiogenesis GO:0002040 53 0.196
anterior lateral line system development GO:0048898 9 0.195
lateral line system development GO:0048925 76 0.195
peptide transport GO:0015833 1 0.191
Rat
cranial nerve development GO:0021545 42 0.189
Zebrafish Mouse
blood vessel morphogenesis GO:0048514 216 0.189
Mouse
blood vessel development GO:0001568 246 0.188
Mouse
rostrocaudal neural tube patterning GO:0021903 29 0.188
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.188
Mouse
angiogenesis GO:0001525 158 0.188
Mouse
regulation of endothelial cell differentiation GO:0045601 3 0.182
stem cell differentiation GO:0048863 117 0.182
Mouse
anterior posterior pattern specification GO:0009952 152 0.180
Zebrafish Fly
embryonic pectoral fin morphogenesis GO:0035118 24 0.179
nucleocytoplasmic transport GO:0006913 4 0.179
regulation of macromolecule metabolic process GO:0060255 317 0.177
Human Zebrafish Mouse Rat Fly
aorta morphogenesis GO:0035909 3 0.174
segmentation GO:0035282 97 0.172
Fly
positive regulation of neurogenesis GO:0050769 24 0.171
cerebellar cortex development GO:0021695 5 0.171
regulation of primary metabolic process GO:0080090 311 0.171
Human Mouse Rat Fly
muscle structure development GO:0061061 196 0.170
determination of left right symmetry GO:0007368 179 0.169
regulation of synapse assembly GO:0051963 3 0.167
cell projection morphogenesis GO:0048858 244 0.167
myeloid cell differentiation GO:0030099 86 0.166
optic nerve development GO:0021554 15 0.166
Zebrafish
cellular biosynthetic process GO:0044249 286 0.165
Human Mouse Rat Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.158
Human Mouse Rat Fly
glial cell migration GO:0008347 3 0.158
localization of cell GO:0051674 244 0.156
Mouse
forebrain generation of neurons GO:0021872 14 0.155
response to abiotic stimulus GO:0009628 122 0.153
Zebrafish
heart contraction GO:0060047 71 0.148
positive regulation of transcription dna templated GO:0045893 57 0.147
Human Mouse Rat Fly
eye photoreceptor cell differentiation GO:0001754 45 0.145
organ growth GO:0035265 12 0.144
peripheral nervous system neuron axonogenesis GO:0048936 13 0.144
negative regulation of multicellular organismal process GO:0051241 69 0.144
Mouse
retinal ganglion cell axon guidance GO:0031290 35 0.143
Zebrafish Mouse
embryonic skeletal system development GO:0048706 97 0.143
dendrite development GO:0016358 9 0.142
Fly
developmental growth GO:0048589 166 0.142
exocrine system development GO:0035272 28 0.141
mesoderm development GO:0007498 88 0.140
determination of bilateral symmetry GO:0009855 204 0.138
forebrain regionalization GO:0021871 4 0.138
regulation of cell differentiation GO:0045595 142 0.136
Mouse
hormone secretion GO:0046879 2 0.135
Rat
embryonic camera type eye morphogenesis GO:0048596 19 0.134
Zebrafish
thyroid gland development GO:0030878 12 0.132
organic cyclic compound biosynthetic process GO:1901362 223 0.132
Human Mouse Rat Fly
positive regulation of multicellular organismal process GO:0051240 52 0.132
Mouse
motor neuron axon guidance GO:0008045 23 0.130
Fly
cellular component morphogenesis GO:0032989 336 0.127
embryonic cranial skeleton morphogenesis GO:0048701 90 0.126
regulation of biological quality GO:0065008 263 0.125
Rat Fly
cellular component assembly GO:0022607 170 0.125
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.123
determination of pancreatic left right asymmetry GO:0035469 11 0.123
cell cycle GO:0007049 93 0.121
endocardium development GO:0003157 9 0.121
cellular component movement GO:0006928 335 0.121
Zebrafish Mouse Fly
neural nucleus development GO:0048857 15 0.120
regeneration GO:0031099 91 0.120
Rat
cardiocyte differentiation GO:0035051 44 0.119
gland development GO:0048732 143 0.118
Mouse Fly
mesodermal cell fate specification GO:0007501 12 0.117
negative regulation of cell development GO:0010721 26 0.116
Mouse
behavior GO:0007610 74 0.116
Zebrafish
convergent extension involved in organogenesis GO:0060029 10 0.115
metencephalon development GO:0022037 27 0.115
venous blood vessel morphogenesis GO:0048845 3 0.114
urogenital system development GO:0001655 97 0.114
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.114
Fly
astrocyte differentiation GO:0048708 1 0.113
notochord cell differentiation GO:0060034 18 0.112
spinal cord motor neuron cell fate specification GO:0021520 8 0.112
Mouse
striated muscle cell differentiation GO:0051146 129 0.112
neuronal stem cell maintenance GO:0097150 2 0.111
regulation of programmed cell death GO:0043067 101 0.110
Mouse
pharynx development GO:0060465 5 0.108
Worm
negative regulation of transcription dna templated GO:0045892 45 0.108
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.108
Mouse
auditory receptor cell development GO:0060117 8 0.107
Zebrafish
glial cell differentiation GO:0010001 42 0.107
morphogenesis of an epithelium GO:0002009 333 0.106
Zebrafish Fly
atrial ventricular junction remodeling GO:0003294 2 0.106
skeletal system development GO:0001501 181 0.106
cerebellum development GO:0021549 17 0.105
positive regulation of developmental process GO:0051094 50 0.102
Mouse
regulation of apoptotic process GO:0042981 98 0.101
Mouse
inner ear development GO:0048839 126 0.101
Zebrafish
axon guidance GO:0007411 86 0.099
Zebrafish Mouse Fly
regulation of synaptic plasticity GO:0048167 1 0.099
erythrocyte development GO:0048821 24 0.099
positive regulation of endothelial cell differentiation GO:0045603 2 0.098
actomyosin structure organization GO:0031032 53 0.097
response to biotic stimulus GO:0009607 97 0.096
optomotor response GO:0071632 1 0.096
Zebrafish
polarized epithelial cell differentiation GO:0030859 4 0.096
negative regulation of neuron differentiation GO:0045665 10 0.095
Mouse
retinal rod cell development GO:0046548 4 0.095
establishment of localization GO:0051234 244 0.095
Rat
muscle cell differentiation GO:0042692 139 0.094
regulation of axonogenesis GO:0050770 32 0.093
notochord development GO:0030903 54 0.091
negative regulation of endothelial cell migration GO:0010596 1 0.089
epidermal cell differentiation GO:0009913 36 0.089
Zebrafish
forebrain neuron differentiation GO:0021879 14 0.088
negative regulation of mesodermal cell fate specification GO:0042662 3 0.088
negative regulation of cellular biosynthetic process GO:0031327 55 0.087
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.087
Mouse
locomotory behavior GO:0007626 34 0.087
somitogenesis GO:0001756 87 0.086
regulation of synapse organization GO:0050807 3 0.085
endodermal cell fate commitment GO:0001711 18 0.083
lymphatic endothelial cell differentiation GO:0060836 1 0.083
regulation of neuron projection development GO:0010975 40 0.083
ventricular cardiac muscle tissue development GO:0003229 3 0.083
Mouse
glial cell fate commitment GO:0021781 6 0.083
regulation of growth GO:0040008 42 0.080
lateral mesoderm development GO:0048368 23 0.078
regulation of localization GO:0032879 104 0.077
Rat
dorsal aorta morphogenesis GO:0035912 3 0.077
exocrine pancreas development GO:0031017 28 0.077
erythrocyte homeostasis GO:0034101 55 0.076
positive regulation of cell fate specification GO:0042660 1 0.076
neuroblast fate commitment GO:0014017 1 0.076
anterior commissure morphogenesis GO:0021960 3 0.075
retinal cone cell differentiation GO:0042670 12 0.074
positive regulation of glial cell differentiation GO:0045687 1 0.073
negative regulation of biosynthetic process GO:0009890 55 0.073
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.071
positive regulation of gliogenesis GO:0014015 2 0.069
response to glucose GO:0009749 3 0.069
sarcomere organization GO:0045214 26 0.068
neuroblast proliferation GO:0007405 2 0.068
cellular response to prostaglandin stimulus GO:0071379 3 0.065
response to carbohydrate GO:0009743 3 0.065
negative regulation of metabolic process GO:0009892 86 0.064
Mouse
neuroepithelial cell differentiation GO:0060563 26 0.064
cardiac atrium morphogenesis GO:0003209 2 0.064
Mouse
cellular response to fatty acid GO:0071398 3 0.064
extracellular fibril organization GO:0043206 1 0.063
pancreatic d cell development GO:0003324 1 0.063
endothelial cell differentiation GO:0045446 20 0.063
response to drug GO:0042493 3 0.063
cardiac cell fate commitment GO:0060911 1 0.062
Human Mouse
kidney development GO:0001822 92 0.062
Zebrafish
negative regulation of neurogenesis GO:0050768 20 0.061
Mouse
negative regulation of programmed cell death GO:0043069 58 0.060
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.059
Human Mouse Rat Fly
developmental maturation GO:0021700 34 0.058
negative regulation of myeloid cell differentiation GO:0045638 1 0.058
gastrulation GO:0007369 208 0.058
positive regulation of cell differentiation GO:0045597 30 0.058
reflex GO:0060004 2 0.057
neuron projection regeneration GO:0031102 16 0.057
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.056
Mouse
heart valve formation GO:0003188 4 0.056
positive regulation of cell cycle GO:0045787 3 0.055
muscle cell development GO:0055001 115 0.055
cardiac ventricle morphogenesis GO:0003208 7 0.053
Mouse
stem cell fate determination GO:0048867 1 0.053
syncytium formation GO:0006949 12 0.053
regulation of vasculature development GO:1901342 33 0.053
Mouse
regulation of signaling GO:0023051 235 0.051
Mouse Rat
oligodendrocyte development GO:0014003 7 0.051
aging GO:0007568 2 0.051
macromolecular complex subunit organization GO:0043933 74 0.051
response to stress GO:0006950 263 0.050
Mouse Rat
neural tube patterning GO:0021532 33 0.050
Zebrafish
hypochord development GO:0055016 3 0.050
midbrain development GO:0030901 28 0.050
nitrogen compound transport GO:0071705 23 0.049
Rat
determination of heart left right asymmetry GO:0061371 117 0.048
negative regulation of apoptotic process GO:0043066 55 0.048
Mouse
regulation of multicellular organism growth GO:0040014 4 0.048
embryonic eye morphogenesis GO:0048048 30 0.047
Zebrafish
cellular component biogenesis GO:0044085 178 0.047
cellular response to chemical stimulus GO:0070887 157 0.047
Rat
cartilage morphogenesis GO:0060536 13 0.046
nuclear transport GO:0051169 4 0.046
cytoskeleton organization GO:0007010 96 0.045
negative regulation of cell death GO:0060548 60 0.045
Mouse
reproduction GO:0000003 40 0.045
embryonic epithelial tube formation GO:0001838 17 0.044
negative regulation of macromolecule metabolic process GO:0010605 76 0.043
Mouse
cardiac muscle tissue morphogenesis GO:0055008 7 0.043
Mouse
transport GO:0006810 220 0.042
Rat
developmental programmed cell death GO:0010623 4 0.042
single organism organelle organization GO:1902589 199 0.042
lateral line nerve development GO:0048892 9 0.041
regulation of binding GO:0051098 3 0.041
Mouse Rat
myeloid cell development GO:0061515 32 0.041
cell migration GO:0016477 237 0.041
Mouse
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.040
peripheral nervous system development GO:0007422 55 0.040
embryonic digestive tract development GO:0048566 4 0.040
cardioblast migration GO:0003260 7 0.039
spinal cord association neuron differentiation GO:0021527 1 0.039
mitotic cell cycle process GO:1903047 48 0.039
cognition GO:0050890 1 0.039
protein complex subunit organization GO:0071822 46 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
Fly
positive regulation of cell death GO:0010942 29 0.038
regulation of epithelial cell differentiation GO:0030856 7 0.038
neural tube formation GO:0001841 16 0.037
epithelial tube formation GO:0072175 19 0.037
muscle organ development GO:0007517 101 0.037
Mouse
cell fate determination GO:0001709 7 0.036
Human Mouse Fly
regulation of dendrite development GO:0050773 3 0.036
regulation of cell cycle GO:0051726 52 0.036
mesoderm morphogenesis GO:0048332 51 0.036
muscle cell fate determination GO:0007521 1 0.036
Fly
digestive tract morphogenesis GO:0048546 231 0.036
medulla oblongata development GO:0021550 4 0.035
ear development GO:0043583 127 0.035
Zebrafish
regulation of system process GO:0044057 40 0.034
stem cell fate commitment GO:0048865 1 0.034
apoptotic process GO:0006915 116 0.034
Mouse
semicircular canal development GO:0060872 24 0.034
Zebrafish
neuroblast differentiation GO:0014016 1 0.034
stem cell proliferation GO:0072089 4 0.034
limbic system development GO:0021761 16 0.033
neural crest cell migration GO:0001755 42 0.033
Mouse
regulation of locomotion GO:0040012 55 0.033
establishment of organelle localization GO:0051656 45 0.032
response to ketone GO:1901654 1 0.032
endocytosis GO:0006897 16 0.032

isl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048