Danio rerio

58 known processes

isl2a

islet2a

(Aliases: isl2,ISL-2,zfIsl-2,wu:fc29g02)

isl2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
brain development GO:0007420 293 0.959
Zebrafish
central nervous system development GO:0007417 387 0.939
Zebrafish Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.891
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.847
Fly
regulation of rna metabolic process GO:0051252 224 0.822
Fly
central nervous system neuron differentiation GO:0021953 74 0.786
Zebrafish Mouse
digestive system development GO:0055123 289 0.782
embryonic organ development GO:0048568 381 0.752
Zebrafish
eye development GO:0001654 277 0.747
Zebrafish
kidney development GO:0001822 92 0.687
Zebrafish
eye morphogenesis GO:0048592 144 0.661
Zebrafish
regulation of developmental process GO:0050793 247 0.661
Mouse
vasculature development GO:0001944 278 0.654
cell fate specification GO:0001708 68 0.652
cell morphogenesis involved in differentiation GO:0000904 195 0.643
pectoral fin morphogenesis GO:0035138 29 0.618
nucleobase containing compound biosynthetic process GO:0034654 205 0.603
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.598
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.588
appendage development GO:0048736 80 0.579
forebrain development GO:0030900 96 0.578
Zebrafish
renal system development GO:0072001 94 0.576
Zebrafish
axon development GO:0061564 166 0.569
chordate embryonic development GO:0043009 271 0.553
Zebrafish
heart development GO:0007507 313 0.550
Zebrafish Fly
camera type eye development GO:0043010 222 0.543
Zebrafish
neuron projection guidance GO:0097485 86 0.541
sympathetic nervous system development GO:0048485 3 0.540
neuron differentiation GO:0030182 353 0.531
axonogenesis GO:0007409 152 0.519
developmental growth involved in morphogenesis GO:0060560 86 0.509
sensory organ morphogenesis GO:0090596 200 0.508
Zebrafish
pectoral fin development GO:0033339 50 0.500
regulation of macromolecule biosynthetic process GO:0010556 225 0.489
Fly
signal transduction GO:0007165 455 0.484
Fly
neuron development GO:0048666 262 0.479
regulation of primary metabolic process GO:0080090 311 0.471
Fly
blood vessel morphogenesis GO:0048514 216 0.464
locomotion GO:0040011 313 0.458
head development GO:0060322 303 0.455
Zebrafish Worm
blood vessel development GO:0001568 246 0.443
facial nerve morphogenesis GO:0021610 1 0.430
ventral spinal cord development GO:0021517 35 0.423
Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.409
Zebrafish
cellular component movement GO:0006928 335 0.409
organic substance biosynthetic process GO:1901576 289 0.404
Fly
cellular biosynthetic process GO:0044249 286 0.401
Fly
motor neuron axon guidance GO:0008045 23 0.400
Fly
cell projection organization GO:0030030 284 0.398
vasculogenesis GO:0001570 41 0.395
cellular component morphogenesis GO:0032989 336 0.384
endocrine system development GO:0035270 65 0.379
Zebrafish
pancreas development GO:0031016 84 0.368
pharyngeal muscle development GO:0043282 4 0.362
axon guidance GO:0007411 86 0.359
angiogenesis GO:0001525 158 0.354
erythrocyte differentiation GO:0030218 54 0.354
macromolecule biosynthetic process GO:0009059 227 0.348
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.348
Zebrafish Fly
pancreatic d cell differentiation GO:0003311 2 0.337
Zebrafish
muscle cell differentiation GO:0042692 139 0.335
Zebrafish Fly
biosynthetic process GO:0009058 294 0.334
Fly
regulation of cellular metabolic process GO:0031323 320 0.324
Fly
nucleic acid templated transcription GO:0097659 181 0.320
Fly
cardiocyte differentiation GO:0035051 44 0.319
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.316
Fly
erythrocyte homeostasis GO:0034101 55 0.304
myeloid cell differentiation GO:0030099 86 0.300
fin morphogenesis GO:0033334 53 0.299
positive regulation of biological process GO:0048518 253 0.294
Fly
negative regulation of biological process GO:0048519 304 0.292
Mouse Fly
endocrine pancreas development GO:0031018 27 0.291
Zebrafish
neuron projection development GO:0031175 180 0.287
outflow tract morphogenesis GO:0003151 1 0.285
embryonic organ morphogenesis GO:0048562 274 0.282
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.274
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.271
Fly
regulation of cell development GO:0060284 100 0.261
Mouse
embryonic heart tube development GO:0035050 133 0.257
immune system development GO:0002520 191 0.255
Fly
hair cell differentiation GO:0035315 32 0.253
Zebrafish
diencephalon development GO:0021536 58 0.226
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.223
Fly
embryonic skeletal system development GO:0048706 97 0.219
skeletal system development GO:0001501 181 0.219
regionalization GO:0003002 274 0.215
Zebrafish Fly
generation of neurons GO:0048699 385 0.209
pancreatic a cell development GO:0003322 2 0.207
Zebrafish
regulation of biological quality GO:0065008 263 0.206
Fly
stem cell proliferation GO:0072089 4 0.205
eye photoreceptor cell development GO:0042462 30 0.204
skeletal system morphogenesis GO:0048705 102 0.191
spinal cord motor neuron differentiation GO:0021522 26 0.191
Zebrafish Mouse
embryonic hemopoiesis GO:0035162 53 0.190
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.186
trigeminal nerve development GO:0021559 3 0.183
spinal cord development GO:0021510 46 0.180
Zebrafish Mouse
retinal rod cell development GO:0046548 4 0.180
posterior lateral line development GO:0048916 38 0.180
determination of dorsal ventral asymmetry GO:0048262 34 0.179
cellular nitrogen compound biosynthetic process GO:0044271 218 0.177
Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.177
Zebrafish
heterocycle metabolic process GO:0046483 290 0.176
Fly
semicircular canal development GO:0060872 24 0.172
Zebrafish
regulation of cell differentiation GO:0045595 142 0.171
Mouse
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.168
pronephros development GO:0048793 69 0.167
Zebrafish
regulation of axonogenesis GO:0050770 32 0.167
nucleobase containing compound metabolic process GO:0006139 274 0.167
Fly
larval development GO:0002164 2 0.165
Worm
retina morphogenesis in camera type eye GO:0060042 79 0.164
embryo development ending in birth or egg hatching GO:0009792 271 0.162
Zebrafish Fly
cardiac cell fate commitment GO:0060911 1 0.158
organic cyclic compound biosynthetic process GO:1901362 223 0.156
Fly
cell fate commitment GO:0045165 99 0.156
hematopoietic or lymphoid organ development GO:0048534 191 0.155
Fly
mechanosensory lateral line system development GO:0048881 49 0.154
cell motility GO:0048870 244 0.154
regulation of axon extension involved in axon guidance GO:0048841 6 0.154
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.153
nephron epithelium morphogenesis GO:0072088 1 0.150
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.147
Fly
positive regulation of transcription dna templated GO:0045893 57 0.147
Fly
myeloid cell homeostasis GO:0002262 56 0.145
chemotaxis GO:0006935 104 0.145
axon extension GO:0048675 45 0.141
positive regulation of metabolic process GO:0009893 108 0.141
Fly
nucleic acid metabolic process GO:0090304 244 0.140
Fly
autonomic nervous system development GO:0048483 19 0.135
positive regulation of macromolecule metabolic process GO:0010604 93 0.133
Fly
sprouting angiogenesis GO:0002040 53 0.133
dorsal ventral pattern formation GO:0009953 125 0.131
exocrine system development GO:0035272 28 0.131
positive regulation of cellular process GO:0048522 201 0.130
Fly
protein complex biogenesis GO:0070271 30 0.130
neuromast mantle cell differentiation GO:0048888 1 0.129
camera type eye morphogenesis GO:0048593 108 0.125
Zebrafish
aging GO:0007568 2 0.124
intracellular estrogen receptor signaling pathway GO:0030520 3 0.124
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.121
cell proliferation involved in heart morphogenesis GO:0061323 2 0.121
septum transversum development GO:0003343 4 0.119
negative regulation of axon guidance GO:1902668 1 0.118
proepicardium development GO:0003342 4 0.117
determination of bilateral symmetry GO:0009855 204 0.116
nephric duct morphogenesis GO:0072178 7 0.116
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.115
atrioventricular valve formation GO:0003190 3 0.114
ear morphogenesis GO:0042471 64 0.114
Zebrafish
auditory receptor cell development GO:0060117 8 0.113
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.113
Fly
regulation of multicellular organismal process GO:0051239 277 0.111
Zebrafish Mouse
regulation of inner ear receptor cell differentiation GO:2000980 1 0.111
regulation of axon guidance GO:1902667 8 0.110
eye photoreceptor cell differentiation GO:0001754 45 0.110
morphogenesis of an epithelial fold GO:0060571 1 0.109
regulation of synapse organization GO:0050807 3 0.107
urogenital system development GO:0001655 97 0.107
Zebrafish
lateral line development GO:0048882 66 0.105
specification of symmetry GO:0009799 204 0.104
neuromast primordium migration GO:0048883 12 0.103
cell proliferation GO:0008283 80 0.103
morphogenesis of an epithelium GO:0002009 333 0.102
Zebrafish Fly
appendage morphogenesis GO:0035107 56 0.102
digestive tract development GO:0048565 265 0.102
Worm
negative regulation of cellular biosynthetic process GO:0031327 55 0.102
gene expression GO:0010467 252 0.102
Zebrafish Fly
muscle cell fate determination GO:0007521 1 0.101
Fly
striated muscle tissue development GO:0014706 110 0.101
Zebrafish
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.101
sensory system development GO:0048880 76 0.100
semicircular canal morphogenesis GO:0048752 18 0.100
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.097
Fly
muscle fiber development GO:0048747 52 0.094
posterior lateral line neuromast primordium migration GO:0048920 12 0.093
cranial nerve development GO:0021545 42 0.092
Zebrafish
inner ear morphogenesis GO:0042472 63 0.092
Zebrafish
cell morphogenesis GO:0000902 289 0.091
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.090
endocrine process GO:0050886 2 0.089
positive regulation of secretion GO:0051047 1 0.088
lateral line system development GO:0048925 76 0.084
regulation of synapse assembly GO:0051963 3 0.084
cellular aromatic compound metabolic process GO:0006725 295 0.083
Fly
glandular epithelial cell differentiation GO:0002067 9 0.083
Zebrafish
neuron projection extension GO:1990138 45 0.083
ventral spinal cord interneuron differentiation GO:0021514 12 0.083
regulation of dendrite development GO:0050773 3 0.082
transcription from rna polymerase ii promoter GO:0006366 80 0.078
Fly
epithelial tube morphogenesis GO:0060562 148 0.077
commissural neuron axon guidance GO:0071679 3 0.076
axon extension involved in axon guidance GO:0048846 10 0.076
axon midline choice point recognition GO:0016199 4 0.074
cellular macromolecule metabolic process GO:0044260 391 0.074
Fly
gastrulation GO:0007369 208 0.073
positive regulation of cell adhesion GO:0045785 1 0.072
developmental cell growth GO:0048588 52 0.072
neural tube development GO:0021915 62 0.071
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.069
Fly
behavior GO:0007610 74 0.069
Zebrafish
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.068
epidermal cell differentiation GO:0009913 36 0.068
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.068
heart valve formation GO:0003188 4 0.067
neurological system process GO:0050877 62 0.067
lymph vessel morphogenesis GO:0036303 25 0.067
ventricular cardiac muscle tissue development GO:0003229 3 0.067
heart process GO:0003015 71 0.066
Zebrafish
formation of primary germ layer GO:0001704 62 0.066
cellular component assembly involved in morphogenesis GO:0010927 107 0.066
regulation of biosynthetic process GO:0009889 250 0.065
Fly
regulation of neuron migration GO:2001222 2 0.065
photoreceptor cell fate specification GO:0043704 1 0.065
muscle structure development GO:0061061 196 0.065
Zebrafish Fly
neuron fate specification GO:0048665 20 0.065
cell migration GO:0016477 237 0.064
ear development GO:0043583 127 0.063
Zebrafish
exocrine pancreas development GO:0031017 28 0.063
regulation of neuron projection development GO:0010975 40 0.062
homeostasis of number of cells GO:0048872 62 0.062
neural retina development GO:0003407 49 0.061
photoreceptor cell fate commitment GO:0046552 1 0.061
circulatory system process GO:0003013 87 0.061
Zebrafish
neural crest cell migration GO:0001755 42 0.061
taxis GO:0042330 109 0.060
embryonic camera type eye development GO:0031076 29 0.060
Zebrafish
myotube cell development GO:0014904 35 0.060
convergent extension involved in organogenesis GO:0060029 10 0.060
neuroepithelial cell differentiation GO:0060563 26 0.060
neuroblast proliferation GO:0007405 2 0.058
regulation of mechanoreceptor differentiation GO:0045631 1 0.058
mesoderm formation GO:0001707 43 0.058
extraocular skeletal muscle development GO:0002074 3 0.058
photoreceptor cell development GO:0042461 40 0.058
rna metabolic process GO:0016070 219 0.058
Fly
optic nerve development GO:0021554 15 0.058
Zebrafish
rna biosynthetic process GO:0032774 181 0.057
Fly
pericardium development GO:0060039 1 0.057
axon choice point recognition GO:0016198 5 0.056
nephron development GO:0072006 31 0.056
Zebrafish
hemopoiesis GO:0030097 183 0.056
cell surface receptor signaling pathway GO:0007166 325 0.055
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
Fly
pancreatic d cell development GO:0003324 1 0.054
Zebrafish
cell part morphogenesis GO:0032990 246 0.053
renal tubule development GO:0061326 5 0.053
ameboidal type cell migration GO:0001667 143 0.052
specification of organ position GO:0010159 3 0.052
regulation of epithelial cell proliferation GO:0050678 3 0.051
kidney epithelium development GO:0072073 23 0.051
embryonic skeletal system morphogenesis GO:0048704 93 0.050
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.050
peripheral nervous system neuron development GO:0048935 22 0.050
Zebrafish
sensory neuron axon guidance GO:0097374 3 0.049
epithelial cell differentiation GO:0030855 116 0.049
Zebrafish
oligodendrocyte cell fate specification GO:0021778 4 0.049
single organism behavior GO:0044708 24 0.049
Zebrafish
positive regulation of gene expression GO:0010628 71 0.048
Fly
mesodermal cell fate specification GO:0007501 12 0.047
protein oligomerization GO:0051259 7 0.047
regulation of neurogenesis GO:0050767 87 0.047
Mouse
positive regulation of rac protein signal transduction GO:0035022 1 0.047
fin development GO:0033333 77 0.047
mesoderm morphogenesis GO:0048332 51 0.046
peripheral nervous system neuron axonogenesis GO:0048936 13 0.045
Zebrafish
nerve development GO:0021675 45 0.045
Zebrafish
muscle cell fate commitment GO:0042693 9 0.045
Fly
nephron tubule morphogenesis GO:0072078 1 0.045
photoreceptor cell differentiation GO:0046530 55 0.044
camera type eye photoreceptor cell differentiation GO:0060219 19 0.044
positive regulation of notch signaling pathway GO:0045747 3 0.044
lymphangiogenesis GO:0001946 25 0.044
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.044
stem cell differentiation GO:0048863 117 0.044
muscle cell development GO:0055001 115 0.044
anatomical structure homeostasis GO:0060249 36 0.043
Fly
positive regulation of protein kinase b signaling GO:0051897 1 0.043
cell migration in hindbrain GO:0021535 7 0.043
myeloid cell development GO:0061515 32 0.043
hematopoietic stem cell differentiation GO:0060218 20 0.043
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.042
striated muscle cell development GO:0055002 108 0.042
lymphatic endothelial cell differentiation GO:0060836 1 0.042
somatic muscle development GO:0007525 4 0.042
muscle organ development GO:0007517 101 0.041
pharyngeal system development GO:0060037 18 0.040
phagocytosis GO:0006909 3 0.040
cell substrate adhesion GO:0031589 4 0.040
cranial ganglion development GO:0061550 3 0.040
positive regulation of cellular biosynthetic process GO:0031328 68 0.039
Fly
regulation of gene expression GO:0010468 265 0.039
Zebrafish Fly
kidney morphogenesis GO:0060993 15 0.039
regulation of nucleic acid templated transcription GO:1903506 213 0.039
Fly
anterior posterior pattern specification GO:0009952 152 0.039
Zebrafish Fly
ectoderm formation GO:0001705 2 0.038
immune system process GO:0002376 241 0.038
Fly
cardiac chamber development GO:0003205 19 0.037
transcription dna templated GO:0006351 181 0.037
Fly
forebrain neuron fate commitment GO:0021877 1 0.037
response to glucocorticoid GO:0051384 1 0.036
regulation of microtubule depolymerization GO:0031114 1 0.036
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.036
localization of cell GO:0051674 244 0.036
cellular ketone metabolic process GO:0042180 11 0.036
protein targeting to nucleus GO:0044744 3 0.035
striated muscle cell differentiation GO:0051146 129 0.035
Zebrafish
ventral spinal cord interneuron specification GO:0021521 3 0.035
positive regulation of cellular metabolic process GO:0031325 94 0.035
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.035
Fly
lymph vessel development GO:0001945 27 0.035
embryonic appendage morphogenesis GO:0035113 30 0.034
neural crest cell differentiation GO:0014033 72 0.034
adult behavior GO:0030534 2 0.034
response to chemical GO:0042221 320 0.034
cell projection assembly GO:0030031 64 0.034
central nervous system neuron development GO:0021954 29 0.034
central nervous system myelin formation GO:0032289 1 0.034
positive regulation of cell cycle GO:0045787 3 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
Fly
axial mesoderm development GO:0048318 10 0.033
cell differentiation in spinal cord GO:0021515 40 0.033
Zebrafish Mouse
skeletal muscle fiber development GO:0048741 35 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
Mouse
heterocycle biosynthetic process GO:0018130 215 0.033
Fly
tube morphogenesis GO:0035239 349 0.032
Zebrafish
endocrine hormone secretion GO:0060986 2 0.032
negative chemotaxis GO:0050919 1 0.031
post anal tail morphogenesis GO:0036342 19 0.031
regulation of organ morphogenesis GO:2000027 35 0.031
embryonic camera type eye morphogenesis GO:0048596 19 0.031
Zebrafish
embryonic eye morphogenesis GO:0048048 30 0.030
Zebrafish
neuron migration GO:0001764 22 0.030
compound eye development GO:0048749 2 0.030
midbrain hindbrain boundary development GO:0030917 23 0.030
Zebrafish
forebrain cell migration GO:0021885 1 0.030
regulation of response to external stimulus GO:0032101 31 0.030
regulation of embryonic development GO:0045995 47 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.030
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.029
cytoskeleton organization GO:0007010 96 0.029
glial cell fate specification GO:0021780 4 0.029
embryonic limb morphogenesis GO:0030326 2 0.029
retina layer formation GO:0010842 24 0.029
heart formation GO:0060914 13 0.029
heart jogging GO:0003146 40 0.029
regulation of cell projection organization GO:0031344 44 0.029
regulation of axon extension GO:0030516 24 0.028
entrainment of circadian clock GO:0009649 2 0.028
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.028
homeostatic process GO:0042592 142 0.027
Fly
sensory organ development GO:0007423 393 0.027
Zebrafish Fly
innervation GO:0060384 3 0.027
regulation of metabolic process GO:0019222 359 0.027
Zebrafish Fly
positive regulation of axon guidance GO:1902669 1 0.027
cardiac chamber formation GO:0003207 4 0.027
heart contraction GO:0060047 71 0.027
Zebrafish
lateral inhibition GO:0046331 1 0.027
nephron morphogenesis GO:0072028 2 0.027
cellular modified amino acid metabolic process GO:0006575 3 0.026
digestive tract morphogenesis GO:0048546 231 0.026
hindbrain development GO:0030902 91 0.026
Zebrafish
regulation of blood circulation GO:1903522 32 0.026
Zebrafish
anterior posterior axon guidance GO:0033564 5 0.026
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.025
preganglionic parasympathetic nervous system development GO:0021783 6 0.025
regulation of cell death GO:0010941 103 0.025
dendrite guidance GO:0070983 0 0.025
Fly
female sex differentiation GO:0046660 4 0.025
regulation of neuron differentiation GO:0045664 56 0.025
Mouse
positive regulation of jak stat cascade GO:0046427 2 0.025
regulation of cell proliferation GO:0042127 37 0.025
neuron projection morphogenesis GO:0048812 161 0.025
positive regulation of stem cell proliferation GO:2000648 1 0.025
heart looping GO:0001947 94 0.025
embryonic heart tube morphogenesis GO:0003143 108 0.025
renal tubule morphogenesis GO:0061333 1 0.024
synaptic target recognition GO:0008039 1 0.024
regulation of extent of cell growth GO:0061387 29 0.024
hematopoietic progenitor cell differentiation GO:0002244 23 0.024
regulation of response to nutrient levels GO:0032107 1 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.023
epithelial tube formation GO:0072175 19 0.023
cell differentiation in hindbrain GO:0021533 5 0.023
regulation of cellular component organization GO:0051128 86 0.023
cellular component assembly GO:0022607 170 0.023
cellular response to retinoic acid GO:0071300 1 0.023
hormone transport GO:0009914 2 0.023
neuronal action potential GO:0019228 18 0.023
organ formation GO:0048645 17 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
cellular component biogenesis GO:0044085 178 0.022
posterior lateral line system development GO:0048915 46 0.022
protein localization to nucleus GO:0034504 3 0.022
notochord cell differentiation GO:0060034 18 0.022
positive regulation of neuron migration GO:2001224 2 0.021
stem cell division GO:0017145 1 0.021
negative regulation of chemotaxis GO:0050922 4 0.021
epidermal cell fate specification GO:0009957 4 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
retinal cone cell differentiation GO:0042670 12 0.021
endothelial cell migration GO:0043542 19 0.021
regulation of cardiac chamber formation GO:1901210 2 0.021
limb bud formation GO:0060174 2 0.021
response to oxygen containing compound GO:1901700 55 0.020
positive regulation of cell proliferation GO:0008284 15 0.020
anterior lateral line nerve development GO:0048909 4 0.020
programmed cell death GO:0012501 119 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.020
Fly
positive regulation of transport GO:0051050 2 0.020
response to nutrient GO:0007584 3 0.020
single organism metabolic process GO:0044710 217 0.020
tor signaling GO:0031929 7 0.020
morphogenesis of a branching structure GO:0001763 21 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
inner ear receptor cell fate commitment GO:0060120 4 0.020
establishment of localization GO:0051234 244 0.020
cardioblast differentiation GO:0010002 9 0.020
transport GO:0006810 220 0.020
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.019
protein heterooligomerization GO:0051291 1 0.019
ventral spinal cord interneuron fate commitment GO:0060579 3 0.019
spinal cord motor neuron cell fate specification GO:0021520 8 0.019
Mouse
transcription from rna polymerase iii promoter GO:0006383 1 0.019
inner ear receptor cell differentiation GO:0060113 29 0.019
Zebrafish
regeneration GO:0031099 91 0.019
primary neural tube formation GO:0014020 1 0.019
mesenchymal cell differentiation GO:0048762 87 0.019
connective tissue development GO:0061448 99 0.019
cell projection morphogenesis GO:0048858 244 0.018
auditory receptor cell fate commitment GO:0009912 4 0.018
cell recognition GO:0008037 19 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
neural crest cell development GO:0014032 62 0.018
developmental process involved in reproduction GO:0003006 27 0.018
Worm
cell growth GO:0016049 57 0.018
positive regulation of embryonic development GO:0040019 3 0.017
somatic motor neuron differentiation GO:0021523 5 0.017
regulation of programmed cell death GO:0043067 101 0.017
negative regulation of myeloid cell differentiation GO:0045638 1 0.017
blood circulation GO:0008015 87 0.017
Zebrafish
tyrosine phosphorylation of stat protein GO:0007260 1 0.017
endodermal cell differentiation GO:0035987 19 0.017
primitive hemopoiesis GO:0060215 27 0.017
regulation of chemotaxis GO:0050920 18 0.017
organelle organization GO:0006996 227 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
patterning of lymph vessels GO:0060854 1 0.017
determination of ventral identity GO:0048264 21 0.017
type b pancreatic cell differentiation GO:0003309 8 0.017
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.017
negative regulation of gene expression GO:0010629 65 0.016
regulation of apoptotic process GO:0042981 98 0.016
myotome development GO:0061055 1 0.016
regulation of nervous system development GO:0051960 90 0.016
Mouse
determination of dorsal identity GO:0048263 13 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
Fly
positive regulation of axonogenesis GO:0050772 6 0.016
pericardium morphogenesis GO:0003344 1 0.016
dendrite development GO:0016358 9 0.016
Fly
cardiac chamber morphogenesis GO:0003206 12 0.016
cardioblast migration GO:0003260 7 0.015
positive regulation of cell substrate adhesion GO:0010811 1 0.015
protein metabolic process GO:0019538 183 0.015
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.015
growth GO:0040007 174 0.015
intermediate mesoderm development GO:0048389 2 0.015
regulation of mesodermal cell fate specification GO:0042661 9 0.015
establishment or maintenance of cell polarity GO:0007163 29 0.015
single organism nuclear import GO:1902593 3 0.015
tube closure GO:0060606 1 0.015
neuroblast fate determination GO:0007400 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
forebrain neuron development GO:0021884 7 0.015
cilium assembly GO:0042384 58 0.015
anatomical structure arrangement GO:0048532 2 0.015
regulation of cell growth GO:0001558 29 0.014
enteric nervous system development GO:0048484 12 0.014
rostrocaudal neural tube patterning GO:0021903 29 0.014
Zebrafish
positive regulation of cell matrix adhesion GO:0001954 1 0.014
nuclear import GO:0051170 3 0.014
regulation of jak stat cascade GO:0046425 3 0.014
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
amine metabolic process GO:0009308 2 0.014
protein complex assembly GO:0006461 30 0.014
gland development GO:0048732 143 0.014
Fly
cellular protein modification process GO:0006464 100 0.014
protein complex subunit organization GO:0071822 46 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
determination of digestive tract left right asymmetry GO:0071907 10 0.014
negative regulation of nucleic acid templated transcription GO:1903507 45 0.014
cell cycle GO:0007049 93 0.014

isl2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 0 0.024
disease of anatomical entity DOID:7 0 0.024
urinary system disease DOID:18 0 0.024