Danio rerio

0 known processes

islr2

immunoglobulin superfamily containing leucine-rich repeat 2

(Aliases: zgc:101901)

islr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism membrane fusion GO:0044801 2 0.620
neuron differentiation GO:0030182 353 0.512
Mouse
regulation of biological quality GO:0065008 263 0.481
Mouse
exocytosis GO:0006887 1 0.424
cell projection organization GO:0030030 284 0.356
Mouse
neuron development GO:0048666 262 0.343
Mouse
neurotransmitter secretion GO:0007269 2 0.332
positive regulation of biological process GO:0048518 253 0.281
Mouse
membrane fusion GO:0061025 2 0.257
organelle fusion GO:0048284 3 0.245
aging GO:0007568 2 0.235
synaptic vesicle transport GO:0048489 1 0.217
positive regulation of cellular process GO:0048522 201 0.211
Mouse
regulation of primary metabolic process GO:0080090 311 0.203
regulation of multicellular organismal development GO:2000026 223 0.195
Mouse
regulation of cell communication GO:0010646 232 0.192
regulation of developmental process GO:0050793 247 0.175
Mouse
synaptic transmission cholinergic GO:0007271 4 0.169
neuromuscular synaptic transmission GO:0007274 2 0.164
regulation of filopodium assembly GO:0051489 2 0.161
regulation of gene expression GO:0010468 265 0.159
generation of neurons GO:0048699 385 0.151
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.131
neurotransmitter transport GO:0006836 2 0.129
system process GO:0003008 185 0.124
regulation of vesicle mediated transport GO:0060627 9 0.118
neurological system process GO:0050877 62 0.114
regulation of synaptic plasticity GO:0048167 1 0.108
regulation of multicellular organismal process GO:0051239 277 0.106
Mouse
regulation of establishment of protein localization GO:0070201 4 0.103
synaptic vesicle localization GO:0097479 1 0.102
regulation of metabolic process GO:0019222 359 0.102
neuron projection morphogenesis GO:0048812 161 0.101
Mouse
negative regulation of biological process GO:0048519 304 0.101
nucleic acid metabolic process GO:0090304 244 0.097
establishment of synaptic vesicle localization GO:0097480 1 0.095
transport GO:0006810 220 0.094
establishment of localization GO:0051234 244 0.090
regulation of synapse organization GO:0050807 3 0.089
cell projection morphogenesis GO:0048858 244 0.088
Mouse
rna localization GO:0006403 4 0.081
neuron neuron synaptic transmission GO:0007270 1 0.081
cell matrix adhesion GO:0007160 4 0.076
cognition GO:0050890 1 0.075
regulation of protein complex assembly GO:0043254 3 0.071
larval development GO:0002164 2 0.068
action potential GO:0001508 19 0.066
regulation of exocytosis GO:0017157 1 0.064
synaptic growth at neuromuscular junction GO:0051124 2 0.063
retina development in camera type eye GO:0060041 146 0.062
positive regulation of transport GO:0051050 2 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
rna metabolic process GO:0016070 219 0.061
developmental growth GO:0048589 166 0.060
Mouse
regulation of glucose transport GO:0010827 1 0.060
organelle organization GO:0006996 227 0.059
neural retina development GO:0003407 49 0.059
regulation of response to stimulus GO:0048583 269 0.058
regulation of nervous system development GO:0051960 90 0.057
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.056
glial cell differentiation GO:0010001 42 0.055
heterocycle metabolic process GO:0046483 290 0.055
axonogenesis GO:0007409 152 0.053
Mouse
embryonic heart tube development GO:0035050 133 0.052
regulation of cell projection assembly GO:0060491 4 0.052
neuron projection development GO:0031175 180 0.052
Mouse
cellular component biogenesis GO:0044085 178 0.051
calcium ion dependent exocytosis GO:0017156 1 0.050
positive regulation of gene expression GO:0010628 71 0.049
cellular component assembly GO:0022607 170 0.049
cellular macromolecule metabolic process GO:0044260 391 0.048
cell substrate adhesion GO:0031589 4 0.047
regulation of cell matrix adhesion GO:0001952 1 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.046
rna biosynthetic process GO:0032774 181 0.046
cell morphogenesis GO:0000902 289 0.045
Mouse
cell cycle arrest GO:0007050 1 0.043
organelle localization GO:0051640 49 0.043
positive regulation of exocytosis GO:0045921 1 0.043
regulation of localization GO:0032879 104 0.043
gliogenesis GO:0042063 45 0.043
regulation of neurogenesis GO:0050767 87 0.042
Mouse
axon ensheathment GO:0008366 18 0.042
cytokinesis GO:0000910 3 0.042
regulation of synapse assembly GO:0051963 3 0.041
regionalization GO:0003002 274 0.040
signal transduction GO:0007165 455 0.040
cell fate commitment GO:0045165 99 0.039
regulation of cell maturation GO:1903429 1 0.038
positive regulation of rna biosynthetic process GO:1902680 57 0.038
establishment of blood brain barrier GO:0060856 2 0.038
regulation of binding GO:0051098 3 0.038
regulation of signaling GO:0023051 235 0.038
regulation of jak stat cascade GO:0046425 3 0.037
regulation of calcium ion dependent exocytosis GO:0017158 1 0.036
transmission of nerve impulse GO:0019226 19 0.035
gene expression GO:0010467 252 0.035
regulation of rna metabolic process GO:0051252 224 0.035
regulation of cell development GO:0060284 100 0.035
Mouse
regulation of intracellular protein transport GO:0033157 3 0.035
cellular component morphogenesis GO:0032989 336 0.035
Mouse
cellular localization GO:0051641 97 0.035
central nervous system development GO:0007417 387 0.034
mitotic cytokinesis GO:0000281 3 0.034
eye development GO:0001654 277 0.033
axon development GO:0061564 166 0.032
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.032
cellular protein complex assembly GO:0043623 19 0.031
response to chemical GO:0042221 320 0.031
regulation of neuron differentiation GO:0045664 56 0.031
Mouse
single organism transport GO:0044765 206 0.031
protein complex assembly GO:0006461 30 0.031
positive regulation of secretion by cell GO:1903532 1 0.030
response to stress GO:0006950 263 0.030
cell cell signaling GO:0007267 52 0.030
multicellular organism growth GO:0035264 4 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
myelination GO:0042552 18 0.029
cellular lipid metabolic process GO:0044255 36 0.029
growth GO:0040007 174 0.029
Mouse
negative regulation of cellular process GO:0048523 283 0.029
multi organism reproductive process GO:0044703 36 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
regulation of cellular component organization GO:0051128 86 0.029
Mouse
regulation of cell projection organization GO:0031344 44 0.028
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.028
neuronal action potential GO:0019228 18 0.028
olfactory bulb development GO:0021772 4 0.028
cranial nerve development GO:0021545 42 0.028
cell part morphogenesis GO:0032990 246 0.028
Mouse
regulation of cell substrate adhesion GO:0010810 1 0.027
establishment of localization in cell GO:0051649 77 0.027
regulation of dendrite development GO:0050773 3 0.027
ensheathment of neurons GO:0007272 18 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
regulation of neurotransmitter levels GO:0001505 5 0.026
reproduction GO:0000003 40 0.026
positive regulation of signaling GO:0023056 56 0.026
digestive system development GO:0055123 289 0.026
regulation of neurotransmitter secretion GO:0046928 1 0.025
heart development GO:0007507 313 0.025
epithelial cell differentiation GO:0030855 116 0.025
stem cell division GO:0017145 1 0.025
chemosensory behavior GO:0007635 1 0.025
regulation of mrna splicing via spliceosome GO:0048024 3 0.025
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
chordate embryonic development GO:0043009 271 0.024
regulation of tube size GO:0035150 2 0.024
single organism metabolic process GO:0044710 217 0.024
calcium mediated signaling GO:0019722 2 0.024
sensory perception of chemical stimulus GO:0007606 3 0.024
anterior posterior pattern specification GO:0009952 152 0.024
cellular component movement GO:0006928 335 0.023
lipid storage GO:0019915 1 0.023
regulation of mrna processing GO:0050684 3 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
multicellular organismal signaling GO:0035637 22 0.022
segmentation GO:0035282 97 0.022
establishment of vesicle localization GO:0051650 24 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regulation of neurotransmitter transport GO:0051588 1 0.022
proepicardium development GO:0003342 4 0.022
muscle cell differentiation GO:0042692 139 0.021
single organism organelle organization GO:1902589 199 0.021
post embryonic morphogenesis GO:0009886 4 0.021
negative regulation of protein complex assembly GO:0031333 1 0.021
regulation of reproductive process GO:2000241 4 0.021
synaptic transmission GO:0007268 35 0.021
regulation of embryonic development GO:0045995 47 0.021
maintenance of location GO:0051235 4 0.020
fertilization GO:0009566 3 0.020
regulation of cellular component biogenesis GO:0044087 12 0.020
central nervous system neuron differentiation GO:0021953 74 0.020
peptide transport GO:0015833 1 0.020
cellular macromolecular complex assembly GO:0034622 24 0.020
protein complex subunit organization GO:0071822 46 0.020
determination of left right symmetry GO:0007368 179 0.020
peptidyl threonine phosphorylation GO:0018107 1 0.020
regulation of cell death GO:0010941 103 0.019
response to organic substance GO:0010033 153 0.019
regulation of biosynthetic process GO:0009889 250 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
regulation of protein transport GO:0051223 3 0.019
cellular ketone metabolic process GO:0042180 11 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
regulation of cell differentiation GO:0045595 142 0.018
Mouse
response to carbohydrate GO:0009743 3 0.018
cardiac cell fate commitment GO:0060911 1 0.018
hormone secretion GO:0046879 2 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
oocyte anterior posterior axis specification GO:0007314 4 0.018
localization of cell GO:0051674 244 0.018
stem cell differentiation GO:0048863 117 0.018
negative regulation of signal transduction GO:0009968 94 0.017
nucleic acid templated transcription GO:0097659 181 0.017
immune system development GO:0002520 191 0.017
homeostatic process GO:0042592 142 0.017
olfactory lobe development GO:0021988 4 0.017
peptidyl threonine modification GO:0018210 1 0.017
protein stabilization GO:0050821 2 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
organic substance transport GO:0071702 58 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
cell death GO:0008219 121 0.017
regulation of biomineral tissue development GO:0070167 2 0.017
myeloid cell development GO:0061515 32 0.016
homeostasis of number of cells GO:0048872 62 0.016
cell cycle process GO:0022402 53 0.016
regulation of protein targeting GO:1903533 2 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
cell proliferation GO:0008283 80 0.016
multi organism process GO:0051704 134 0.016
cytoplasm organization GO:0007028 4 0.016
water homeostasis GO:0030104 4 0.016
peripheral nervous system neuron development GO:0048935 22 0.016
transcription dna templated GO:0006351 181 0.016
retina layer formation GO:0010842 24 0.016
gastrulation GO:0007369 208 0.016
negative regulation of gliogenesis GO:0014014 1 0.016
hemopoiesis GO:0030097 183 0.016
protein polymerization GO:0051258 4 0.016
kidney development GO:0001822 92 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
cell cycle GO:0007049 93 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
negative regulation of cellular component organization GO:0051129 16 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
regulation of cellular localization GO:0060341 12 0.015
regulation of endothelial cell differentiation GO:0045601 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
cytoskeleton organization GO:0007010 96 0.015
organic substance biosynthetic process GO:1901576 289 0.015
digestive tract development GO:0048565 265 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
microtubule based process GO:0007017 60 0.015
organic acid metabolic process GO:0006082 31 0.015
oxoacid metabolic process GO:0043436 31 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
response to amino acid GO:0043200 2 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
nuclear transport GO:0051169 4 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
cellular biosynthetic process GO:0044249 286 0.014
regulation of signal transduction GO:0009966 225 0.014
blood vessel development GO:0001568 246 0.014
protein metabolic process GO:0019538 183 0.014
negative regulation of cell communication GO:0010648 96 0.014
vesicle mediated transport GO:0016192 22 0.014
neuroblast proliferation GO:0007405 2 0.014
microtubule polymerization or depolymerization GO:0031109 3 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
cellular protein metabolic process GO:0044267 129 0.014
locomotion GO:0040011 313 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
lamellipodium organization GO:0097581 1 0.013
biological adhesion GO:0022610 40 0.013
blood vessel morphogenesis GO:0048514 216 0.013
mesenchyme development GO:0060485 127 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
establishment of organelle localization GO:0051656 45 0.013
protein complex biogenesis GO:0070271 30 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
response to other organism GO:0051707 97 0.013
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.013
single organism localization GO:1902578 225 0.013
macromolecular complex assembly GO:0065003 35 0.013
circulatory system process GO:0003013 87 0.013
oligodendrocyte differentiation GO:0048709 23 0.013
regeneration GO:0031099 91 0.013
regulation of cell shape GO:0008360 1 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
Mouse
protein targeting to membrane GO:0006612 1 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
synaptic vesicle recycling GO:0036465 1 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
intracellular mrna localization GO:0008298 1 0.012
immune system process GO:0002376 241 0.012
protein localization to plasma membrane GO:0072659 1 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
cell adhesion GO:0007155 40 0.012
glial cell development GO:0021782 20 0.012
sexual reproduction GO:0019953 36 0.012
response to hexose GO:0009746 3 0.012
response to drug GO:0042493 3 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
response to external stimulus GO:0009605 264 0.012
taxis GO:0042330 109 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
synaptic target recognition GO:0008039 1 0.012
negative regulation of developmental process GO:0051093 65 0.011
negative regulation of nervous system development GO:0051961 22 0.011
tube morphogenesis GO:0035239 349 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
response to abiotic stimulus GO:0009628 122 0.011
regulation of membrane potential GO:0042391 23 0.011
determination of bilateral symmetry GO:0009855 204 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
protein depolymerization GO:0051261 1 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
central nervous system neuron development GO:0021954 29 0.011
hormone transport GO:0009914 2 0.011
regulation of bone mineralization GO:0030500 2 0.011
biosynthetic process GO:0009058 294 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of transport GO:0051049 45 0.011
sensory organ development GO:0007423 393 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
embryonic organ development GO:0048568 381 0.011
septum transversum development GO:0003343 4 0.011
regulation of glucose import GO:0046324 1 0.011
stem cell maintenance GO:0019827 4 0.011
vesicle localization GO:0051648 27 0.011
axon cargo transport GO:0008088 2 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
filopodium assembly GO:0046847 5 0.011
thermosensory behavior GO:0040040 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
regulation of calcium mediated signaling GO:0050848 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
regulation of transcription dna templated GO:0006355 213 0.011
cell motility GO:0048870 244 0.010
amine metabolic process GO:0009308 2 0.010
establishment of nucleus localization GO:0040023 7 0.010
developmental maturation GO:0021700 34 0.010
forebrain development GO:0030900 96 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
head development GO:0060322 303 0.010
cellular protein complex disassembly GO:0043624 1 0.010
sympathetic nervous system development GO:0048485 3 0.010
response to corticosteroid GO:0031960 1 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
nuclear import GO:0051170 3 0.010
anterior posterior axis specification GO:0009948 20 0.010
response to monosaccharide GO:0034284 3 0.010

islr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025