|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
1 |
0.740
|
Mouse |
|
|
pericardium morphogenesis
|
GO:0003344 |
1 |
0.725
|
Fly |
|
|
post embryonic organ development
|
GO:0048569 |
4 |
0.504
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.499
|
Mouse |
|
|
larval development
|
GO:0002164 |
2 |
0.487
|
Fly |
|
|
larval heart development
|
GO:0007508 |
2 |
0.448
|
Fly |
|
|
multicellular organismal metabolic process
|
GO:0044236 |
2 |
0.437
|
Human |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
1 |
0.426
|
Mouse |
|
|
collagen metabolic process
|
GO:0032963 |
2 |
0.426
|
Human |
|
|
response to nutrient
|
GO:0007584 |
3 |
0.404
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
2 |
0.364
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.348
|
Human |
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.342
|
Fly |
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
1 |
0.340
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
1 |
0.324
|
Human |
|
|
digestive system development
|
GO:0055123 |
289 |
0.322
|
Human Zebrafish Fly |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
1 |
0.310
|
Human |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.300
|
Mouse |
|
|
response to drug
|
GO:0042493 |
3 |
0.293
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.288
|
Human Zebrafish Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
2 |
0.281
|
Mouse |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.275
|
Fly |
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
3 |
0.256
|
Fly |
|
|
response to vitamin
|
GO:0033273 |
3 |
0.256
|
|
|
|
sarcomere organization
|
GO:0045214 |
26 |
0.254
|
Mouse |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
18 |
0.249
|
Mouse |
|
|
regulation of collagen metabolic process
|
GO:0010712 |
2 |
0.245
|
Human |
|
|
localization of cell
|
GO:0051674 |
244 |
0.243
|
Human Zebrafish Mouse Worm Fly |
|
|
aging
|
GO:0007568 |
2 |
0.243
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.242
|
Mouse |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.228
|
Zebrafish |
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.221
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.221
|
Mouse Fly |
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.220
|
Fly |
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
8 |
0.218
|
Mouse |
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.217
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.206
|
Mouse Worm |
|
|
blood vessel development
|
GO:0001568 |
246 |
0.205
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.205
|
Human Mouse Fly |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
1 |
0.204
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
74 |
0.202
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.202
|
Mouse |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.200
|
Mouse Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.199
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.198
|
Mouse |
|
|
signal transduction
|
GO:0007165 |
455 |
0.195
|
Human Mouse |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.189
|
Human Zebrafish Mouse Worm Fly |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.189
|
Mouse |
|
|
actomyosin structure organization
|
GO:0031032 |
53 |
0.188
|
Mouse Fly |
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.187
|
Zebrafish |
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
2 |
0.184
|
Human |
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.183
|
Mouse Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.174
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.168
|
Mouse Fly |
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.167
|
Mouse |
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.166
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.164
|
Human |
|
|
homeostatic process
|
GO:0042592 |
142 |
0.164
|
Fly |
|
|
immune system process
|
GO:0002376 |
241 |
0.163
|
Human Fly |
|
|
cell cycle
|
GO:0007049 |
93 |
0.162
|
Mouse |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.161
|
Fly |
|
|
cognition
|
GO:0050890 |
1 |
0.158
|
Mouse |
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.154
|
Mouse |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
1 |
0.153
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.151
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.150
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
1 |
0.149
|
|
|
|
cell migration in hindbrain
|
GO:0021535 |
7 |
0.148
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
8 |
0.148
|
Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.148
|
Human Zebrafish Fly |
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.146
|
Mouse Fly |
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.146
|
Fly |
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.145
|
Fly |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.145
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
51 |
0.143
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.142
|
Mouse Fly |
|
|
head development
|
GO:0060322 |
303 |
0.141
|
Mouse |
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
1 |
0.140
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.138
|
Mouse Fly |
|
|
hindbrain development
|
GO:0030902 |
91 |
0.138
|
Mouse |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.138
|
Zebrafish |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.137
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.136
|
Zebrafish Mouse Fly |
|
|
tissue migration
|
GO:0090130 |
37 |
0.135
|
Mouse Fly |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.134
|
Worm |
|
|
apical junction assembly
|
GO:0043297 |
1 |
0.134
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.134
|
Mouse Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.133
|
Fly |
|
|
death
|
GO:0016265 |
121 |
0.131
|
Human Worm |
|
|
system process
|
GO:0003008 |
185 |
0.129
|
Mouse Worm Fly |
|
|
locomotion
|
GO:0040011 |
313 |
0.129
|
Human Zebrafish Mouse Worm Fly |
|
|
immune system development
|
GO:0002520 |
191 |
0.129
|
Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.127
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.126
|
Mouse Fly |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.126
|
Human Zebrafish Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.126
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.125
|
Human Mouse Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.125
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.125
|
Human Zebrafish Mouse Worm Fly |
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.123
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.122
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.122
|
Mouse Fly |
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.120
|
Mouse |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.120
|
Human Mouse Worm |
|
|
single organism transport
|
GO:0044765 |
206 |
0.119
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.119
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.117
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.115
|
Human Worm |
|
|
muscle contraction
|
GO:0006936 |
18 |
0.115
|
Worm |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.115
|
Mouse |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
49 |
0.114
|
Fly |
|
|
response to chemical
|
GO:0042221 |
320 |
0.113
|
Fly |
|
|
neurological system process
|
GO:0050877 |
62 |
0.113
|
Mouse Fly |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.111
|
Fly |
|
|
vasculature development
|
GO:0001944 |
278 |
0.110
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
48 |
0.110
|
Mouse |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
1 |
0.109
|
|
|
|
biological adhesion
|
GO:0022610 |
40 |
0.108
|
Human Mouse Fly |
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.105
|
Human |
|
|
axon development
|
GO:0061564 |
166 |
0.104
|
Mouse Fly |
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
1 |
0.104
|
Human |
|
|
cell projection organization
|
GO:0030030 |
284 |
0.104
|
Mouse Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.104
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.103
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.102
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.101
|
Mouse |
|
|
sprouting angiogenesis
|
GO:0002040 |
53 |
0.101
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.101
|
Mouse |
|
|
muscle organ development
|
GO:0007517 |
101 |
0.100
|
Fly |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.097
|
Human |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.096
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.096
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.095
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.093
|
|
|
|
kupffer s vesicle development
|
GO:0070121 |
50 |
0.093
|
Zebrafish |
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.092
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.092
|
Mouse |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.092
|
Mouse |
|
|
taxis
|
GO:0042330 |
109 |
0.092
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.090
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.090
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
5 |
0.089
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.089
|
Mouse Fly |
|
|
epithelium migration
|
GO:0090132 |
25 |
0.088
|
Mouse Fly |
|
|
cellular extravasation
|
GO:0045123 |
1 |
0.088
|
Human |
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.087
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.087
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
30 |
0.087
|
Mouse |
|
|
establishment of localization
|
GO:0051234 |
244 |
0.086
|
Human |
|
|
heart development
|
GO:0007507 |
313 |
0.086
|
Mouse Fly |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.086
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.085
|
Mouse Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.085
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
26 |
0.084
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.084
|
Human Worm |
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.082
|
Mouse Fly |
|
|
muscle structure development
|
GO:0061061 |
196 |
0.081
|
Mouse Worm Fly |
|
|
skeletal muscle organ development
|
GO:0060538 |
78 |
0.081
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.080
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.080
|
Mouse Fly |
|
|
cell cycle process
|
GO:0022402 |
53 |
0.080
|
Mouse |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.079
|
|
|
|
myofibril assembly
|
GO:0030239 |
48 |
0.079
|
Mouse |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
3 |
0.079
|
|
|
|
tissue homeostasis
|
GO:0001894 |
25 |
0.079
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
39 |
0.078
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.078
|
Human Zebrafish Mouse Worm Fly |
|
|
single organism localization
|
GO:1902578 |
225 |
0.077
|
Human |
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.076
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.076
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.076
|
Mouse Fly |
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.075
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.075
|
Human |
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.074
|
Fly |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.074
|
Human |
|
|
response to other organism
|
GO:0051707 |
97 |
0.073
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.073
|
Fly |
|
|
mesoderm development
|
GO:0007498 |
88 |
0.073
|
Human |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.072
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.070
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.070
|
Human Worm |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.069
|
|
|
|
muscle system process
|
GO:0003012 |
20 |
0.068
|
Worm |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.068
|
|
|
|
muscle attachment
|
GO:0016203 |
9 |
0.068
|
Fly |
|
|
transport
|
GO:0006810 |
220 |
0.067
|
|
|
|
germ cell migration
|
GO:0008354 |
8 |
0.067
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
265 |
0.067
|
Human Zebrafish Fly |
|
|
actin filament based process
|
GO:0030029 |
64 |
0.067
|
Mouse Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
19 |
0.066
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.065
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.065
|
Mouse Fly |
|
|
neuron development
|
GO:0048666 |
262 |
0.065
|
Mouse Fly |
|
|
actin filament bundle organization
|
GO:0061572 |
6 |
0.064
|
Fly |
|
|
axon guidance
|
GO:0007411 |
86 |
0.064
|
Fly |
|
|
response to lipid
|
GO:0033993 |
60 |
0.063
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.062
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.062
|
Mouse |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.061
|
Human Mouse Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.061
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.061
|
Fly |
|
|
cell fate specification
|
GO:0001708 |
68 |
0.061
|
Mouse |
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.061
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
1 |
0.061
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
24 |
0.061
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.060
|
Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
9 |
0.060
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.058
|
|
|
|
chemical homeostasis
|
GO:0048878 |
49 |
0.058
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.058
|
Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.057
|
Mouse |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.057
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.057
|
Mouse |
|
|
striated muscle contraction
|
GO:0006941 |
12 |
0.056
|
Worm |
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.056
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
15 |
0.056
|
Human |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.056
|
Human |
|
|
neuron projection development
|
GO:0031175 |
180 |
0.056
|
Mouse Fly |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.056
|
Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
12 |
0.055
|
|
|
|
mesoderm formation
|
GO:0001707 |
43 |
0.055
|
Human |
|
|
stress fiber assembly
|
GO:0043149 |
5 |
0.055
|
Fly |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.055
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.054
|
Mouse Fly |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
29 |
0.054
|
Fly |
|
|
sensory organ development
|
GO:0007423 |
393 |
0.054
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.054
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
17 |
0.053
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.053
|
|
|
|
visual behavior
|
GO:0007632 |
10 |
0.053
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
152 |
0.052
|
Mouse Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
9 |
0.052
|
Mouse |
|
|
transmission of nerve impulse
|
GO:0019226 |
19 |
0.052
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.052
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
3 |
0.052
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
44 |
0.051
|
Mouse |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.051
|
Mouse Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
29 |
0.051
|
Human |
|
|
response to activity
|
GO:0014823 |
14 |
0.051
|
|
|
|
cell junction organization
|
GO:0034330 |
11 |
0.050
|
|
|
|
response to alcohol
|
GO:0097305 |
14 |
0.050
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.050
|
Mouse |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.049
|
Mouse Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
14 |
0.049
|
Worm |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.049
|
Fly |
|
|
protein secretion
|
GO:0009306 |
1 |
0.049
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.049
|
Human |
|
|
glucose import
|
GO:0046323 |
2 |
0.048
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.048
|
Human |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.048
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.047
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
3 |
0.047
|
|
|
|
single organism membrane organization
|
GO:0044802 |
20 |
0.047
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.047
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.047
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.046
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.046
|
Mouse Fly |
|
|
cation homeostasis
|
GO:0055080 |
33 |
0.046
|
|
|
|
actin filament organization
|
GO:0007015 |
15 |
0.046
|
Fly |
|
|
pericardium development
|
GO:0060039 |
1 |
0.045
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.045
|
|
|
|
protein localization to membrane
|
GO:0072657 |
9 |
0.045
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
22 |
0.044
|
Mouse |
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.044
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.044
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
17 |
0.043
|
Fly |
|
|
stem cell development
|
GO:0048864 |
82 |
0.043
|
Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.043
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.043
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.043
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.043
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.042
|
Worm Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.042
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.042
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.042
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.042
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
55 |
0.041
|
|
|
|
single organism cellular localization
|
GO:1902580 |
46 |
0.041
|
Human |
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.040
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.040
|
|
|
|
ion homeostasis
|
GO:0050801 |
41 |
0.040
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
11 |
0.040
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.040
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
11 |
0.040
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
11 |
0.040
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.040
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
1 |
0.040
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.039
|
Mouse |
|
|
muscle cell development
|
GO:0055001 |
115 |
0.039
|
Mouse Worm |
|
|
protein activation cascade
|
GO:0072376 |
6 |
0.039
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.039
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.038
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.038
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.038
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.037
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.037
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
17 |
0.037
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
11 |
0.037
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
1 |
0.036
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.036
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.036
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.036
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.036
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.036
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.036
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.036
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.036
|
Mouse |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.036
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.036
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.035
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
15 |
0.035
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.035
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.035
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
40 |
0.035
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.035
|
Mouse Fly |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
4 |
0.034
|
|
|
|
neuron projection extension
|
GO:1990138 |
45 |
0.034
|
Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
17 |
0.034
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.034
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
40 |
0.034
|
Human Mouse Fly |
|
|
epithelial cell migration
|
GO:0010631 |
25 |
0.033
|
Mouse Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.033
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.033
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.033
|
Fly |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.033
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
3 |
0.033
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.033
|
|
|
|
activation of mapk activity
|
GO:0000187 |
3 |
0.033
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.033
|
Human Fly |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
4 |
0.032
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
1 |
0.032
|
|
|
|
developmental cell growth
|
GO:0048588 |
52 |
0.032
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.032
|
Human |
|
|
adherens junction organization
|
GO:0034332 |
4 |
0.032
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
11 |
0.032
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.031
|
Mouse Fly |
|
|
axon extension
|
GO:0048675 |
45 |
0.031
|
Mouse |
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.031
|
|
|
|
endomembrane system organization
|
GO:0010256 |
13 |
0.031
|
Human |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
1 |
0.031
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.031
|
|
|
|
hormone transport
|
GO:0009914 |
2 |
0.031
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.031
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.031
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.031
|
Human Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.030
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
3 |
0.030
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
20 |
0.030
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
56 |
0.030
|
|
|
|
growth
|
GO:0040007 |
174 |
0.030
|
Mouse Fly |
|
|
nuclear import
|
GO:0051170 |
3 |
0.030
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.030
|
|
|
|
endothelial cell migration
|
GO:0043542 |
19 |
0.030
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.030
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.030
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.029
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.029
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.029
|
Fly |
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.029
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.029
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.029
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.029
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.029
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
1 |
0.029
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
4 |
0.029
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.028
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
6 |
0.028
|
Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.028
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
5 |
0.028
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.028
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.028
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.028
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
1 |
0.027
|
|
|
|
cellular response to lipid
|
GO:0071396 |
39 |
0.027
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.027
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.027
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.027
|
Human |
|
|
b cell mediated immunity
|
GO:0019724 |
3 |
0.027
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.027
|
Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.027
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.027
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
2 |
0.027
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.027
|
|
|
|
response to oxidative stress
|
GO:0006979 |
11 |
0.026
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
22 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.026
|
|
|
|
regulation of immune system process
|
GO:0002682 |
34 |
0.026
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.026
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
25 |
0.026
|
|
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.026
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.026
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.026
|
Mouse Fly |
|
|
stem cell division
|
GO:0017145 |
1 |
0.026
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
13 |
0.026
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
1 |
0.025
|
|
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.025
|
Human |
|
|
regulation of glucose transport
|
GO:0010827 |
1 |
0.025
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.025
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.025
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.025
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.025
|
Mouse |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
9 |
0.025
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.025
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
1 |
0.025
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.025
|
Fly |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
20 |
0.025
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.025
|
Fly |
|
|
nitric oxide metabolic process
|
GO:0046209 |
2 |
0.025
|
|
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.024
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
18 |
0.024
|
Fly |
|
|
female gonad development
|
GO:0008585 |
4 |
0.024
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
5 |
0.024
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
63 |
0.024
|
Mouse Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.024
|
Mouse |
|
|
regulation of glucose import
|
GO:0046324 |
1 |
0.024
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.024
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
15 |
0.024
|
Worm |
|
|
peptidyl amino acid modification
|
GO:0018193 |
16 |
0.024
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
9 |
0.024
|
|
|
|
peptide transport
|
GO:0015833 |
1 |
0.023
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.023
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
9 |
0.023
|
Fly |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.023
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.023
|
|
|
|
response to ketone
|
GO:1901654 |
1 |
0.023
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.023
|
Fly |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.023
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.023
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.022
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.022
|
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.022
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.022
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
1 |
0.022
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
7 |
0.022
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
31 |
0.022
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.022
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
3 |
0.022
|
|
|
|
defense response to other organism
|
GO:0098542 |
33 |
0.022
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.022
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
30 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
21 |
0.022
|
Human |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.021
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.021
|
|
|
|
ion transport
|
GO:0006811 |
114 |
0.021
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
4 |
0.021
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.021
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.021
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.021
|
|
|
|
sensory perception of pain
|
GO:0019233 |
1 |
0.021
|
|
|
|
multi organism cellular process
|
GO:0044764 |
2 |
0.021
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.021
|
Mouse |
|
|
cellular response to vitamin
|
GO:0071295 |
1 |
0.020
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
1 |
0.020
|
|
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.020
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.020
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.020
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
2 |
0.020
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
2 |
0.020
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.020
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.020
|
Mouse Worm Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
16 |
0.020
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
14 |
0.020
|
|
|
|
tight junction assembly
|
GO:0070830 |
1 |
0.020
|
|
|
|
protein localization
|
GO:0008104 |
40 |
0.020
|
Human |
|
|
ear development
|
GO:0043583 |
127 |
0.020
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
15 |
0.019
|
|
|
|
positive regulation of glucose transport
|
GO:0010828 |
1 |
0.019
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.019
|
Human |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.019
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
17 |
0.019
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
4 |
0.019
|
|
|
|
protein acetylation
|
GO:0006473 |
2 |
0.019
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
4 |
0.019
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
17 |
0.019
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
1 |
0.019
|
|
|
|
neuronal action potential
|
GO:0019228 |
18 |
0.019
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.019
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.019
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.018
|
|
|
|
regulation of transport
|
GO:0051049 |
45 |
0.018
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
2 |
0.018
|
|
|
|
cranial nerve development
|
GO:0021545 |
42 |
0.018
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
2 |
0.018
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.018
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.018
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.018
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
3 |
0.018
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
43 |
0.018
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.018
|
|
