Danio rerio

0 known processes

itm2bb

integral membrane protein 2Bb

(Aliases: wu:fb94b03,zgc:64142,itm2bl)

itm2bb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.472
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.434
immune system process GO:0002376 241 0.321
response to bacterium GO:0009617 58 0.281
i kappab kinase nf kappab signaling GO:0007249 4 0.259
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.218
regulation of protein localization to nucleus GO:1900180 2 0.169
embryo development ending in birth or egg hatching GO:0009792 271 0.141
cellular protein metabolic process GO:0044267 129 0.130
cellular amide metabolic process GO:0043603 4 0.123
nuclear transport GO:0051169 4 0.119
cellular response to chemical stimulus GO:0070887 157 0.115
response to biotic stimulus GO:0009607 97 0.112
regulation of signaling GO:0023051 235 0.108
maintenance of location GO:0051235 4 0.107
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.105
Human
gene expression GO:0010467 252 0.103
hematopoietic or lymphoid organ development GO:0048534 191 0.098
nucleocytoplasmic transport GO:0006913 4 0.095
neural nucleus development GO:0048857 15 0.095
single organism nuclear import GO:1902593 3 0.094
protein import into nucleus GO:0006606 3 0.093
positive regulation of biological process GO:0048518 253 0.092
nuclear import GO:0051170 3 0.090
superoxide metabolic process GO:0006801 2 0.089
neutrophil migration GO:1990266 10 0.088
regulation of biosynthetic process GO:0009889 250 0.086
Human
multicellular organism growth GO:0035264 4 0.085
innate immune response GO:0045087 13 0.084
protein localization to nucleus GO:0034504 3 0.076
neuron differentiation GO:0030182 353 0.075
granulocyte migration GO:0097530 11 0.074
protein targeting to nucleus GO:0044744 3 0.071
establishment of protein localization to organelle GO:0072594 4 0.070
positive regulation of inflammatory response GO:0050729 1 0.069
lipid digestion GO:0044241 3 0.067
regulation of cytokine production GO:0001817 3 0.063
regulation of multicellular organism growth GO:0040014 4 0.058
cellular macromolecule metabolic process GO:0044260 391 0.058
Human
cell projection organization GO:0030030 284 0.058
regulation of signal transduction GO:0009966 225 0.056
smooth muscle contraction GO:0006939 2 0.056
epithelial tube morphogenesis GO:0060562 148 0.055
protein metabolic process GO:0019538 183 0.055
Human
regulation of response to stimulus GO:0048583 269 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.053
Human
response to alkaloid GO:0043279 2 0.051
neutrophil mediated immunity GO:0002446 1 0.051
locomotion GO:0040011 313 0.050
defense response GO:0006952 47 0.048
biosynthetic process GO:0009058 294 0.048
Human
xenobiotic metabolic process GO:0006805 4 0.048
response to chemical GO:0042221 320 0.048
regulation of intracellular signal transduction GO:1902531 57 0.047
retina development in camera type eye GO:0060041 146 0.047
negative regulation of protein transport GO:0051224 3 0.046
positive regulation of cellular catabolic process GO:0031331 3 0.046
positive regulation of catabolic process GO:0009896 4 0.045
immune response GO:0006955 28 0.044
regulation of cell communication GO:0010646 232 0.042
regulation of endopeptidase activity GO:0052548 23 0.042
larval development GO:0002164 2 0.042
positive regulation of signaling GO:0023056 56 0.041
response to stress GO:0006950 263 0.041
death GO:0016265 121 0.041
Mouse
lipid storage GO:0019915 1 0.041
transcription dna templated GO:0006351 181 0.040
positive regulation of response to stimulus GO:0048584 80 0.039
negative regulation of response to stimulus GO:0048585 104 0.039
heterocycle metabolic process GO:0046483 290 0.039
cell morphogenesis involved in differentiation GO:0000904 195 0.037
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.037
protein import GO:0017038 3 0.036
multicellular organismal macromolecule metabolic process GO:0044259 2 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
regulation of developmental process GO:0050793 247 0.036
signal transduction GO:0007165 455 0.036
Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.036
response to other organism GO:0051707 97 0.035
cellular response to molecule of bacterial origin GO:0071219 3 0.035
cellular localization GO:0051641 97 0.035
cellular biosynthetic process GO:0044249 286 0.034
Human
cellular protein catabolic process GO:0044257 4 0.034
organic cyclic compound metabolic process GO:1901360 301 0.033
positive regulation of transport GO:0051050 2 0.033
cell morphogenesis GO:0000902 289 0.033
negative regulation of cytoplasmic transport GO:1903650 2 0.033
response to metal ion GO:0010038 34 0.032
tube morphogenesis GO:0035239 349 0.031
regulation of metabolic process GO:0019222 359 0.031
Human
reactive oxygen species metabolic process GO:0072593 6 0.031
intracellular signal transduction GO:0035556 85 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.031
multi organism process GO:0051704 134 0.030
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.030
neuron development GO:0048666 262 0.030
regulation of response to external stimulus GO:0032101 31 0.030
myeloid leukocyte migration GO:0097529 12 0.029
response to organic substance GO:0010033 153 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.028
determination of bilateral symmetry GO:0009855 204 0.028
leukocyte mediated cytotoxicity GO:0001909 1 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
regulation of response to oxidative stress GO:1902882 2 0.028
response to inorganic substance GO:0010035 38 0.028
negative regulation of intracellular transport GO:0032387 3 0.027
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
cellular component movement GO:0006928 335 0.026
aging GO:0007568 2 0.026
regulation of protein targeting GO:1903533 2 0.026
regulation of primary metabolic process GO:0080090 311 0.026
Human
immune system development GO:0002520 191 0.026
apoptotic process GO:0006915 116 0.025
Mouse
axon development GO:0061564 166 0.025
regulation of cell projection assembly GO:0060491 4 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
regulation of innate immune response GO:0045088 11 0.025
regulation of protein metabolic process GO:0051246 56 0.025
Human
intestinal cholesterol absorption GO:0030299 2 0.025
cell surface receptor signaling pathway GO:0007166 325 0.024
Mouse
phagocytosis GO:0006909 3 0.024
regulation of proteolysis GO:0030162 24 0.024
response to external biotic stimulus GO:0043207 97 0.024
neuron projection morphogenesis GO:0048812 161 0.024
regulation of gene expression GO:0010468 265 0.024
hemopoiesis GO:0030097 183 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
endosome to lysosome transport GO:0008333 1 0.023
negative regulation of cytokine production GO:0001818 1 0.023
response to amino acid GO:0043200 2 0.023
response to transition metal nanoparticle GO:1990267 28 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
cellular response to biotic stimulus GO:0071216 3 0.023
homeostasis of number of cells GO:0048872 62 0.022
protein localization GO:0008104 40 0.022
regulation of locomotion GO:0040012 55 0.022
oxidoreduction coenzyme metabolic process GO:0006733 1 0.022
regulation of response to stress GO:0080134 36 0.022
defense response to fungus GO:0050832 2 0.022
regulation of biological quality GO:0065008 263 0.021
neuron projection development GO:0031175 180 0.021
blood vessel development GO:0001568 246 0.021
negative regulation of signaling GO:0023057 96 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
Human
retina morphogenesis in camera type eye GO:0060042 79 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
regulation of cellular extravasation GO:0002691 1 0.020
regulation of protein transport GO:0051223 3 0.020
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 1 0.020
response to wounding GO:0009611 116 0.019
negative regulation of protein localization to nucleus GO:1900181 2 0.019
negative regulation of signal transduction GO:0009968 94 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
plasma membrane repair GO:0001778 2 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
cellular catabolic process GO:0044248 27 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
developmental cell growth GO:0048588 52 0.018
cytokinesis GO:0000910 3 0.018
intestinal absorption GO:0050892 2 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
cellular response to prostaglandin stimulus GO:0071379 3 0.017
gtp metabolic process GO:0046039 4 0.017
vasculature development GO:0001944 278 0.017
regulation of rac protein signal transduction GO:0035020 1 0.017
angiogenesis GO:0001525 158 0.017
macromolecule localization GO:0033036 54 0.017
ph reduction GO:0045851 1 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
autophagy GO:0006914 4 0.016
regulation of programmed cell death GO:0043067 101 0.016
membrane invagination GO:0010324 1 0.016
regulation of immune system process GO:0002682 34 0.016
homeostatic process GO:0042592 142 0.016
regulation of cell development GO:0060284 100 0.016
regulation of gtpase activity GO:0043087 2 0.015
epithelial cell differentiation GO:0030855 116 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
transcription from rna polymerase iii promoter GO:0006383 1 0.015
collagen metabolic process GO:0032963 2 0.015
regulation of cellular component organization GO:0051128 86 0.015
myeloid leukocyte mediated immunity GO:0002444 1 0.015
central nervous system development GO:0007417 387 0.015
generation of neurons GO:0048699 385 0.015
negative regulation of defense response GO:0031348 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
leukocyte migration GO:0050900 15 0.014
heart development GO:0007507 313 0.014
regulation of rho protein signal transduction GO:0035023 2 0.014
proteolysis GO:0006508 38 0.014
taxis GO:0042330 109 0.014
oxidation reduction process GO:0055114 41 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
single organism localization GO:1902578 225 0.014
head development GO:0060322 303 0.014
astrocyte differentiation GO:0048708 1 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
positive regulation of immune effector process GO:0002699 3 0.014
nucleic acid metabolic process GO:0090304 244 0.014
cell projection morphogenesis GO:0048858 244 0.014
single organism cellular localization GO:1902580 46 0.014
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.014
peptide metabolic process GO:0006518 1 0.013
neutrophil chemotaxis GO:0030593 10 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
Human
regulation of protein catabolic process GO:0042176 1 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.013
immune effector process GO:0002252 23 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
leukocyte chemotaxis GO:0030595 12 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
rna metabolic process GO:0016070 219 0.013
cellular response to organic substance GO:0071310 105 0.013
myeloid cell development GO:0061515 32 0.013
regulation of sterol transport GO:0032371 3 0.013
heart morphogenesis GO:0003007 156 0.013
positive regulation of innate immune response GO:0045089 8 0.012
single organismal cell cell adhesion GO:0016337 29 0.012
hydrogen peroxide metabolic process GO:0042743 2 0.012
axonogenesis GO:0007409 152 0.012
response to mercury ion GO:0046689 1 0.012
nucleic acid templated transcription GO:0097659 181 0.012
cell motility GO:0048870 244 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
Human
regulation of reproductive process GO:2000241 4 0.012
macromolecule catabolic process GO:0009057 15 0.012
defense response to other organism GO:0098542 33 0.012
regulation of cell activation GO:0050865 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.012
growth GO:0040007 174 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
cellular response to oxygen levels GO:0071453 1 0.012
stem cell maintenance GO:0019827 4 0.012
hindbrain development GO:0030902 91 0.012
regulation of rna metabolic process GO:0051252 224 0.012
leukocyte activation GO:0045321 12 0.012
response to copper ion GO:0046688 13 0.012
system process GO:0003008 185 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of tube size GO:0035150 2 0.011
respiratory burst GO:0045730 2 0.011
response to nicotine GO:0035094 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
tissue homeostasis GO:0001894 25 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
meiotic nuclear division GO:0007126 4 0.011
regulation of neutrophil migration GO:1902622 6 0.011
protein complex localization GO:0031503 1 0.011
negative regulation of biological process GO:0048519 304 0.011
Human
myeloid cell homeostasis GO:0002262 56 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of cytokine production GO:0001819 2 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
positive regulation of cell killing GO:0031343 2 0.010
regulation of peptidase activity GO:0052547 23 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
blood vessel morphogenesis GO:0048514 216 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
regulation of inflammatory response GO:0050727 2 0.010

itm2bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.188
immune system disease DOID:2914 0 0.055
nervous system disease DOID:863 0 0.051
cardiovascular system disease DOID:1287 0 0.036
inherited metabolic disorder DOID:655 0 0.029
disease of metabolism DOID:0014667 0 0.029
Human