Danio rerio

0 known processes

ivd

isovaleryl Coenzyme A dehydrogenase

(Aliases: wu:fb34d07,si:dz181p14.1,sb:cb425)

ivd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 3 0.946
Rat
cellular respiration GO:0045333 3 0.893
small molecule catabolic process GO:0044282 3 0.625
Rat
dicarboxylic acid metabolic process GO:0043648 1 0.591
alpha amino acid metabolic process GO:1901605 3 0.450
Rat
respiratory electron transport chain GO:0022904 2 0.447
branched chain amino acid metabolic process GO:0009081 1 0.416
Rat
hydrogen peroxide metabolic process GO:0042743 2 0.385
lipid oxidation GO:0034440 1 0.355
organic acid catabolic process GO:0016054 3 0.324
Rat
oxoacid metabolic process GO:0043436 31 0.304
Rat
fatty acid beta oxidation GO:0006635 1 0.300
organic acid metabolic process GO:0006082 31 0.272
Rat
generation of precursor metabolites and energy GO:0006091 5 0.257
carboxylic acid metabolic process GO:0019752 22 0.234
Rat
cellular lipid catabolic process GO:0044242 3 0.223
regulation of gene expression GO:0010468 265 0.221
atp synthesis coupled electron transport GO:0042773 1 0.200
cellular macromolecule metabolic process GO:0044260 391 0.200
cellular modified amino acid metabolic process GO:0006575 3 0.196
electron transport chain GO:0022900 2 0.182
aging GO:0007568 2 0.179
larval development GO:0002164 2 0.170
organonitrogen compound biosynthetic process GO:1901566 47 0.163
transport GO:0006810 220 0.154
organic cyclic compound metabolic process GO:1901360 301 0.145
oxidation reduction process GO:0055114 41 0.143
Human Rat
heterocycle metabolic process GO:0046483 290 0.142
organic substance biosynthetic process GO:1901576 289 0.140
small molecule metabolic process GO:0044281 77 0.138
Rat
fatty acid catabolic process GO:0009062 1 0.138
response to drug GO:0042493 3 0.131
cellular nitrogen compound metabolic process GO:0034641 290 0.131
cellular biosynthetic process GO:0044249 286 0.121
cellular amino acid biosynthetic process GO:0008652 2 0.118
mitochondrion organization GO:0007005 4 0.114
reactive oxygen species metabolic process GO:0072593 6 0.112
regulation of multicellular organism growth GO:0040014 4 0.111
single organism metabolic process GO:0044710 217 0.100
Human Rat
oxidative phosphorylation GO:0006119 1 0.099
cellular aromatic compound metabolic process GO:0006725 295 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.095
carboxylic acid biosynthetic process GO:0046394 12 0.094
nucleobase containing compound biosynthetic process GO:0034654 205 0.093
nucleobase containing compound metabolic process GO:0006139 274 0.093
response to nutrient GO:0007584 3 0.092
biosynthetic process GO:0009058 294 0.085
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.085
lipid catabolic process GO:0016042 4 0.084
fatty acid oxidation GO:0019395 1 0.084
regulation of macromolecule biosynthetic process GO:0010556 225 0.083
cellular nitrogen compound biosynthetic process GO:0044271 218 0.076
cellular amino acid metabolic process GO:0006520 7 0.073
Rat
regulation of primary metabolic process GO:0080090 311 0.072
nucleic acid metabolic process GO:0090304 244 0.071
cellular macromolecule biosynthetic process GO:0034645 224 0.069
rna metabolic process GO:0016070 219 0.068
regulation of cellular metabolic process GO:0031323 320 0.067
regulation of mrna processing GO:0050684 3 0.067
regulation of biological quality GO:0065008 263 0.066
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.066
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.065
lipid storage GO:0019915 1 0.065
organic cyclic compound biosynthetic process GO:1901362 223 0.064
nitrogen compound metabolic process GO:0006807 319 0.063
Rat
regulation of cellular biosynthetic process GO:0031326 245 0.063
regulation of fatty acid metabolic process GO:0019217 1 0.057
heart development GO:0007507 313 0.057
cellular amide metabolic process GO:0043603 4 0.056
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
regulation of rna metabolic process GO:0051252 224 0.054
multicellular organism growth GO:0035264 4 0.053
maintenance of location GO:0051235 4 0.052
regulation of biosynthetic process GO:0009889 250 0.051
gland development GO:0048732 143 0.050
macromolecule biosynthetic process GO:0009059 227 0.049
immune system process GO:0002376 241 0.049
positive regulation of biological process GO:0048518 253 0.049
rna biosynthetic process GO:0032774 181 0.048
regulation of protein catabolic process GO:0042176 1 0.046
regulation of nucleic acid templated transcription GO:1903506 213 0.045
liver development GO:0001889 96 0.045
phagocytosis GO:0006909 3 0.044
monocarboxylic acid catabolic process GO:0072329 3 0.044
organic acid biosynthetic process GO:0016053 12 0.043
phagocytosis engulfment GO:0006911 1 0.041
gene expression GO:0010467 252 0.041
response to hydrogen peroxide GO:0042542 3 0.041
nucleic acid templated transcription GO:0097659 181 0.040
energy derivation by oxidation of organic compounds GO:0015980 5 0.040
protein metabolic process GO:0019538 183 0.039
response to bacterium GO:0009617 58 0.039
cellular response to extracellular stimulus GO:0031668 2 0.039
establishment of localization GO:0051234 244 0.038
negative regulation of cellular process GO:0048523 283 0.038
alternative mrna splicing via spliceosome GO:0000380 1 0.038
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.036
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
superoxide metabolic process GO:0006801 2 0.035
tube morphogenesis GO:0035239 349 0.035
cellular component assembly GO:0022607 170 0.034
cellular component biogenesis GO:0044085 178 0.034
catabolic process GO:0009056 32 0.033
Rat
embryo development ending in birth or egg hatching GO:0009792 271 0.032
aromatic compound biosynthetic process GO:0019438 217 0.032
response to uv GO:0009411 3 0.032
regulation of cytoplasmic transport GO:1903649 4 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
cellular catabolic process GO:0044248 27 0.029
Rat
regulation of transcription dna templated GO:0006355 213 0.029
single organism localization GO:1902578 225 0.029
autophagy GO:0006914 4 0.028
protein import GO:0017038 3 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
transcription dna templated GO:0006351 181 0.027
mitochondrial transport GO:0006839 2 0.026
removal of superoxide radicals GO:0019430 2 0.026
protein homooligomerization GO:0051260 3 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
microtubule organizing center organization GO:0031023 1 0.025
cellular response to external stimulus GO:0071496 2 0.025
organelle organization GO:0006996 227 0.025
regulation of blood vessel size GO:0050880 2 0.025
negative regulation of kinase activity GO:0033673 4 0.024
response to stress GO:0006950 263 0.024
cellular ketone metabolic process GO:0042180 11 0.024
energy reserve metabolic process GO:0006112 2 0.024
regulation of rna biosynthetic process GO:2001141 213 0.023
cellular response to stress GO:0033554 62 0.023
cellular response to oxygen radical GO:0071450 2 0.023
regulation of mrna splicing via spliceosome GO:0048024 3 0.022
response to copper ion GO:0046688 13 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
death GO:0016265 121 0.022
cellular response to nutrient levels GO:0031669 2 0.022
proteolysis GO:0006508 38 0.022
response to superoxide GO:0000303 2 0.022
programmed cell death GO:0012501 119 0.022
gastrulation GO:0007369 208 0.021
digestive tract morphogenesis GO:0048546 231 0.021
signal transduction GO:0007165 455 0.021
regulation of rho protein signal transduction GO:0035023 2 0.021
tissue remodeling GO:0048771 4 0.021
cell death in response to oxidative stress GO:0036473 2 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
determination of left right symmetry GO:0007368 179 0.021
locomotion GO:0040011 313 0.021
negative regulation of cell communication GO:0010648 96 0.020
sulfur compound metabolic process GO:0006790 13 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
stem cell maintenance GO:0019827 4 0.020
cellular protein catabolic process GO:0044257 4 0.020
response to external stimulus GO:0009605 264 0.020
response to oxidative stress GO:0006979 11 0.020
negative regulation of signaling GO:0023057 96 0.020
regulation of metabolic process GO:0019222 359 0.020
regulation of jun kinase activity GO:0043506 3 0.020
regulation of tube size GO:0035150 2 0.020
organic substance catabolic process GO:1901575 28 0.019
Rat
positive regulation of cellular process GO:0048522 201 0.019
negative regulation of catabolic process GO:0009895 3 0.019
digestive system development GO:0055123 289 0.018
double strand break repair GO:0006302 3 0.018
regulation of response to biotic stimulus GO:0002831 2 0.018
establishment of localization in cell GO:0051649 77 0.018
nuclear transport GO:0051169 4 0.018
sulfur compound biosynthetic process GO:0044272 9 0.018
cytoskeleton organization GO:0007010 96 0.018
lipid homeostasis GO:0055088 3 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
membrane invagination GO:0010324 1 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.017
growth GO:0040007 174 0.017
transmembrane transport GO:0055085 120 0.017
cellular response to reactive oxygen species GO:0034614 2 0.017
small molecule biosynthetic process GO:0044283 16 0.017
negative regulation of biological process GO:0048519 304 0.016
immune system development GO:0002520 191 0.016
hepaticobiliary system development GO:0061008 98 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
single organism nuclear import GO:1902593 3 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of organelle assembly GO:1902115 4 0.016
activation of mapk activity GO:0000187 3 0.016
cellular protein metabolic process GO:0044267 129 0.015
response to inorganic substance GO:0010035 38 0.015
negative regulation of gene expression GO:0010629 65 0.015
positive regulation of blood circulation GO:1903524 2 0.015
pyruvate metabolic process GO:0006090 1 0.015
positive regulation of rna metabolic process GO:0051254 59 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
regulation of apoptotic process GO:0042981 98 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
cellular aldehyde metabolic process GO:0006081 4 0.015
negative regulation of defense response GO:0031348 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
peptide metabolic process GO:0006518 1 0.015
apoptotic process GO:0006915 116 0.015
protein dephosphorylation GO:0006470 3 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of signaling GO:0023051 235 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
translational initiation GO:0006413 3 0.014
protein complex assembly GO:0006461 30 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
antimicrobial humoral response GO:0019730 2 0.014
embryonic heart tube development GO:0035050 133 0.014
macromolecular complex assembly GO:0065003 35 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
blood circulation GO:0008015 87 0.014
homeostatic process GO:0042592 142 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
cell aging GO:0007569 2 0.014
regulation of protein transport GO:0051223 3 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
muscle tissue development GO:0060537 110 0.014
nuclear import GO:0051170 3 0.013
spermatid development GO:0007286 2 0.013
muscle structure development GO:0061061 196 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
protein import into nucleus GO:0006606 3 0.013
response to chemical GO:0042221 320 0.013
meiotic nuclear division GO:0007126 4 0.013
determination of bilateral symmetry GO:0009855 204 0.013
multi organism process GO:0051704 134 0.013
myeloid cell differentiation GO:0030099 86 0.013
cellular amine metabolic process GO:0044106 2 0.013
peptidyl lysine methylation GO:0018022 3 0.013
regulation of blood pressure GO:0008217 1 0.013
cell death GO:0008219 121 0.013
sensory organ morphogenesis GO:0090596 200 0.013
germ line stem cell maintenance GO:0030718 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.012
negative regulation of heart contraction GO:0045822 2 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
regulation of cell death GO:0010941 103 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
response to nicotine GO:0035094 2 0.012
protein stabilization GO:0050821 2 0.012
monocarboxylic acid metabolic process GO:0032787 17 0.012
mononuclear cell proliferation GO:0032943 1 0.012
positive regulation of transport GO:0051050 2 0.012
leukocyte proliferation GO:0070661 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.012
hormone metabolic process GO:0042445 19 0.012
adult behavior GO:0030534 2 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
positive regulation of cell adhesion GO:0045785 1 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
brain development GO:0007420 293 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.011
response to oxygen radical GO:0000305 2 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.011
regulation of membrane potential GO:0042391 23 0.011
cellular response to starvation GO:0009267 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
regulation of muscle contraction GO:0006937 3 0.011
regulation of signal transduction GO:0009966 225 0.011
cellular response to oxidative stress GO:0034599 5 0.011
protein localization to nucleus GO:0034504 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
urogenital system development GO:0001655 97 0.011
response to metal ion GO:0010038 34 0.011
hemopoiesis GO:0030097 183 0.011
somatic muscle development GO:0007525 4 0.011
peptide transport GO:0015833 1 0.011
cell part morphogenesis GO:0032990 246 0.011
cell projection organization GO:0030030 284 0.010
protein complex biogenesis GO:0070271 30 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
positive regulation of catabolic process GO:0009896 4 0.010
cellular protein modification process GO:0006464 100 0.010
regulation of cell communication GO:0010646 232 0.010
developmental growth GO:0048589 166 0.010
inorganic ion transmembrane transport GO:0098660 57 0.010
b cell activation GO:0042113 2 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
smooth muscle contraction GO:0006939 2 0.010
system process GO:0003008 185 0.010
fin regeneration GO:0031101 51 0.010
gtp catabolic process GO:0006184 2 0.010

ivd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.588
Human
inherited metabolic disorder DOID:655 0 0.588
Human
mitochondrial metabolism disease DOID:700 0 0.022
amino acid metabolic disorder DOID:9252 0 0.022
Human
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.015
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
heart disease DOID:114 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cardiovascular system disease DOID:1287 0 0.012
muscle tissue disease DOID:66 0 0.012
cardiomyopathy DOID:0050700 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011