Danio rerio

26 known processes

jak1

Janus kinase 1

jak1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.740
Human Mouse
negative regulation of biological process GO:0048519 304 0.553
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.514
cognition GO:0050890 1 0.512
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.443
immune system development GO:0002520 191 0.425
protein metabolic process GO:0019538 183 0.369
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.361
Fly
regulation of multicellular organismal process GO:0051239 277 0.355
Fly
convergent extension involved in gastrulation GO:0060027 71 0.345
Fly
organic cyclic compound metabolic process GO:1901360 301 0.340
hematopoietic or lymphoid organ development GO:0048534 191 0.333
single organism localization GO:1902578 225 0.326
heterocycle biosynthetic process GO:0018130 215 0.310
organic cyclic compound biosynthetic process GO:1901362 223 0.285
meiotic nuclear division GO:0007126 4 0.276
regulation of cell shape GO:0008360 1 0.273
Fly
signal transduction GO:0007165 455 0.272
Human Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.271
hemopoiesis GO:0030097 183 0.263
rna metabolic process GO:0016070 219 0.259
regulation of biological quality GO:0065008 263 0.247
Fly
cellular biosynthetic process GO:0044249 286 0.241
positive regulation of biological process GO:0048518 253 0.240
maintenance of location GO:0051235 4 0.239
establishment of localization GO:0051234 244 0.239
multicellular organism growth GO:0035264 4 0.237
regulation of rna biosynthetic process GO:2001141 213 0.232
regulation of macromolecule metabolic process GO:0060255 317 0.230
response to organic substance GO:0010033 153 0.228
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.223
regulation of transcription dna templated GO:0006355 213 0.218
aromatic compound biosynthetic process GO:0019438 217 0.216
transcription dna templated GO:0006351 181 0.211
larval development GO:0002164 2 0.209
Fly
gene expression GO:0010467 252 0.209
cell motility GO:0048870 244 0.208
Fly
nucleic acid metabolic process GO:0090304 244 0.207
aging GO:0007568 2 0.207
regulation of rna metabolic process GO:0051252 224 0.202
regulation of developmental process GO:0050793 247 0.201
Fly
cellular protein metabolic process GO:0044267 129 0.200
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.198
response to chemical GO:0042221 320 0.198
Human Mouse
regulation of gene expression GO:0010468 265 0.196
tube morphogenesis GO:0035239 349 0.196
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.191
actin filament based movement GO:0030048 1 0.190
Fly
programmed cell death GO:0012501 119 0.186
transport GO:0006810 220 0.186
positive regulation of transport GO:0051050 2 0.181
cellular nitrogen compound metabolic process GO:0034641 290 0.180
regulation of cellular biosynthetic process GO:0031326 245 0.178
regulation of multicellular organism growth GO:0040014 4 0.177
response to external stimulus GO:0009605 264 0.177
Fly
macromolecule modification GO:0043412 111 0.176
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.174
single organism transport GO:0044765 206 0.172
negative regulation of cellular process GO:0048523 283 0.171
Fly
segmentation GO:0035282 97 0.170
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.166
regulation of autophagy GO:0010506 3 0.164
digestive tract development GO:0048565 265 0.161
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.160
metal ion transport GO:0030001 58 0.157
cell morphogenesis involved in differentiation GO:0000904 195 0.156
Fly
regulation of multicellular organismal development GO:2000026 223 0.155
Fly
morphogenesis of an epithelium GO:0002009 333 0.154
Fly
response to other organism GO:0051707 97 0.152
Fly
epithelial cell differentiation GO:0030855 116 0.150
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.148
cellular response to organic substance GO:0071310 105 0.146
Human Mouse
homeostatic process GO:0042592 142 0.145
rna biosynthetic process GO:0032774 181 0.144
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.138
regulation of metal ion transport GO:0010959 4 0.133
actin filament based process GO:0030029 64 0.130
Fly
cell death GO:0008219 121 0.128
apoptotic process GO:0006915 116 0.128
nucleobase containing compound biosynthetic process GO:0034654 205 0.127
regulation of metabolic process GO:0019222 359 0.125
cellular macromolecule biosynthetic process GO:0034645 224 0.125
regulation of biosynthetic process GO:0009889 250 0.123
cell surface receptor signaling pathway GO:0007166 325 0.121
Human Mouse
death GO:0016265 121 0.120
convergent extension GO:0060026 118 0.119
Fly
regulation of cell communication GO:0010646 232 0.119
Fly
regulation of primary metabolic process GO:0080090 311 0.119
phagocytosis GO:0006909 3 0.119
jak stat cascade GO:0007259 5 0.118
Fly
phosphorylation GO:0016310 69 0.117
Human Mouse
protein modification process GO:0036211 100 0.117
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.116
regulation of programmed cell death GO:0043067 101 0.111
response to stress GO:0006950 263 0.111
Fly
heterocycle metabolic process GO:0046483 290 0.111
response to external biotic stimulus GO:0043207 97 0.111
Fly
defense response GO:0006952 47 0.107
Fly
lipid storage GO:0019915 1 0.107
regulation of response to stimulus GO:0048583 269 0.106
Fly
regulation of transport GO:0051049 45 0.102
localization of cell GO:0051674 244 0.101
Fly
sensory organ development GO:0007423 393 0.100
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.098
response to drug GO:0042493 3 0.097
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.096
gastrulation GO:0007369 208 0.095
Fly
regulation of cell differentiation GO:0045595 142 0.094
Fly
multi organism process GO:0051704 134 0.094
Fly
regulation of embryonic development GO:0045995 47 0.093
Fly
cortical cytoskeleton organization GO:0030865 1 0.093
regulation of cell proliferation GO:0042127 37 0.092
Fly
blood vessel morphogenesis GO:0048514 216 0.092
compound eye development GO:0048749 2 0.092
Fly
nucleocytoplasmic transport GO:0006913 4 0.091
regulation of macromolecule biosynthetic process GO:0010556 225 0.091
embryo development ending in birth or egg hatching GO:0009792 271 0.091
cation homeostasis GO:0055080 33 0.089
synaptic vesicle localization GO:0097479 1 0.089
small molecule metabolic process GO:0044281 77 0.089
regulation of apoptotic process GO:0042981 98 0.087
meiotic cell cycle process GO:1903046 3 0.087
guanosine containing compound catabolic process GO:1901069 2 0.085
peptidyl serine modification GO:0018209 2 0.085
developmental growth GO:0048589 166 0.083
negative regulation of developmental process GO:0051093 65 0.083
Fly
negative regulation of protein complex assembly GO:0031333 1 0.083
post golgi vesicle mediated transport GO:0006892 1 0.082
cell projection organization GO:0030030 284 0.081
regulation of cellular metabolic process GO:0031323 320 0.081
positive regulation of immune response GO:0050778 11 0.080
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.079
locomotor rhythm GO:0045475 3 0.077
Fly
cellular component movement GO:0006928 335 0.075
Fly
chemical homeostasis GO:0048878 49 0.075
immune system process GO:0002376 241 0.074
phosphate containing compound metabolic process GO:0006796 108 0.073
Human Mouse
neuron projection regeneration GO:0031102 16 0.073
t cell differentiation GO:0030217 6 0.072
macromolecule biosynthetic process GO:0009059 227 0.072
biosynthetic process GO:0009058 294 0.071
cell migration involved in gastrulation GO:0042074 79 0.071
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.071
Fly
response to virus GO:0009615 21 0.070
Fly
cellular protein modification process GO:0006464 100 0.070
Human Mouse
phosphorus metabolic process GO:0006793 109 0.069
Human Mouse
generation of neurons GO:0048699 385 0.069
Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.069
regulation of cell death GO:0010941 103 0.069
b cell activation GO:0042113 2 0.068
vacuolar transport GO:0007034 2 0.068
regulation of production of molecular mediator of immune response GO:0002700 1 0.067
regulation of response to cytokine stimulus GO:0060759 3 0.066
regulation of cytokine production GO:0001817 3 0.066
membrane fusion GO:0061025 2 0.066
digestive system development GO:0055123 289 0.065
Fly
growth GO:0040007 174 0.065
epithelial cell morphogenesis GO:0003382 2 0.065
Fly
cellular response to chemical stimulus GO:0070887 157 0.064
Human Mouse
regulation of protein complex assembly GO:0043254 3 0.064
single organism organelle organization GO:1902589 199 0.063
regulation of erk1 and erk2 cascade GO:0070372 4 0.062
organelle fusion GO:0048284 3 0.062
establishment of protein localization to organelle GO:0072594 4 0.062
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.062
neurotransmitter transport GO:0006836 2 0.062
heart development GO:0007507 313 0.062
nuclear transport GO:0051169 4 0.061
protein phosphorylation GO:0006468 47 0.061
Human Mouse
ameboidal type cell migration GO:0001667 143 0.061
Fly
cellular response to endogenous stimulus GO:0071495 68 0.060
erk1 and erk2 cascade GO:0070371 4 0.060
negative regulation of multicellular organismal process GO:0051241 69 0.059
response to corticosteroid GO:0031960 1 0.058
positive regulation of secretion by cell GO:1903532 1 0.058
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.057
neuron development GO:0048666 262 0.057
synaptic vesicle transport GO:0048489 1 0.056
exocytosis GO:0006887 1 0.056
b cell differentiation GO:0030183 1 0.056
response to axon injury GO:0048678 14 0.056
guanosine containing compound metabolic process GO:1901068 4 0.056
cell morphogenesis GO:0000902 289 0.056
Fly
positive regulation of biosynthetic process GO:0009891 68 0.055
endosome organization GO:0007032 2 0.054
regulation of calcium ion transport GO:0051924 2 0.054
homeostasis of number of cells GO:0048872 62 0.054
endosomal transport GO:0016197 2 0.053
multi organism reproductive process GO:0044703 36 0.053
Fly
cellular protein catabolic process GO:0044257 4 0.053
negative regulation of cell differentiation GO:0045596 46 0.053
Fly
locomotion GO:0040011 313 0.053
Fly
positive regulation of cell activation GO:0050867 1 0.053
regulation of localization GO:0032879 104 0.052
defense response to other organism GO:0098542 33 0.052
Fly
negative regulation of cytokine production GO:0001818 1 0.051
production of molecular mediator of immune response GO:0002440 2 0.051
cation transport GO:0006812 81 0.051
autophagy GO:0006914 4 0.051
cytokinesis GO:0000910 3 0.051
synaptic vesicle recycling GO:0036465 1 0.051
neurotransmitter secretion GO:0007269 2 0.051
protein import into nucleus GO:0006606 3 0.051
cell migration GO:0016477 237 0.051
Fly
negative regulation of response to stimulus GO:0048585 104 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.050
regulation of cell projection assembly GO:0060491 4 0.050
t cell differentiation in thymus GO:0033077 6 0.050
positive regulation of muscle cell differentiation GO:0051149 1 0.050
cell projection morphogenesis GO:0048858 244 0.050
neuron projection morphogenesis GO:0048812 161 0.050
epithelial cell development GO:0002064 42 0.050
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.049
Mouse
positive regulation of map kinase activity GO:0043406 3 0.049
positive regulation of gene expression GO:0010628 71 0.049
cell substrate adhesion GO:0031589 4 0.049
heart morphogenesis GO:0003007 156 0.049
reproduction GO:0000003 40 0.048
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.048
response to biotic stimulus GO:0009607 97 0.048
Fly
nuclear export GO:0051168 1 0.048
carbohydrate homeostasis GO:0033500 1 0.047
leukocyte proliferation GO:0070661 1 0.047
stem cell proliferation GO:0072089 4 0.046
gtp catabolic process GO:0006184 2 0.046
amine metabolic process GO:0009308 2 0.046
cellular component morphogenesis GO:0032989 336 0.046
Fly
gtp metabolic process GO:0046039 4 0.046
negative regulation of immune response GO:0050777 2 0.046
negative regulation of cell death GO:0060548 60 0.046
membrane invagination GO:0010324 1 0.046
negative regulation of signaling GO:0023057 96 0.046
regulation of cellular ketone metabolic process GO:0010565 7 0.046
positive regulation of apoptotic signaling pathway GO:2001235 1 0.046
organonitrogen compound metabolic process GO:1901564 74 0.046
vasculature development GO:0001944 278 0.045
single organism metabolic process GO:0044710 217 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.044
meiotic chromosome segregation GO:0045132 3 0.044
organelle organization GO:0006996 227 0.044
positive regulation of cellular biosynthetic process GO:0031328 68 0.044
positive regulation of cell cycle GO:0045787 3 0.044
regulation of cytoplasmic transport GO:1903649 4 0.044
regulation of immune response GO:0050776 14 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
cell proliferation GO:0008283 80 0.044
Fly
embryonic pattern specification GO:0009880 44 0.043
Fly
reproductive process GO:0022414 40 0.043
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.043
regulation of nucleocytoplasmic transport GO:0046822 2 0.043
positive regulation of cellular process GO:0048522 201 0.043
positive regulation of macromolecule metabolic process GO:0010604 93 0.043
cellular response to organic cyclic compound GO:0071407 38 0.042
response to glucocorticoid GO:0051384 1 0.042
establishment of synaptic vesicle localization GO:0097480 1 0.042
regulation of immune system process GO:0002682 34 0.042
Fly
regulation of neurotransmitter secretion GO:0046928 1 0.042
protein dephosphorylation GO:0006470 3 0.042
glucose homeostasis GO:0042593 1 0.042
regulation of myotube differentiation GO:0010830 2 0.042
leukocyte homeostasis GO:0001776 2 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.041
periodic partitioning GO:0007365 1 0.041
Fly
negative regulation of apoptotic process GO:0043066 55 0.041
lymphocyte homeostasis GO:0002260 1 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
negative regulation of protein transport GO:0051224 3 0.040
ion transport GO:0006811 114 0.039
regionalization GO:0003002 274 0.039
Fly
carboxylic acid metabolic process GO:0019752 22 0.039
negative regulation of intracellular protein transport GO:0090317 3 0.039
regulation of organ growth GO:0046620 3 0.039
cellular amine metabolic process GO:0044106 2 0.039
adult behavior GO:0030534 2 0.039
anterior posterior pattern specification GO:0009952 152 0.039
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.039
system process GO:0003008 185 0.039
Fly
single organism membrane fusion GO:0044801 2 0.038
response to wounding GO:0009611 116 0.038
regulation of protein transport GO:0051223 3 0.038
regulation of establishment of protein localization GO:0070201 4 0.037
positive regulation of secretion GO:0051047 1 0.037
regulation of dna templated transcription in response to stress GO:0043620 0 0.037
developmental process involved in reproduction GO:0003006 27 0.037
Fly
cellular chemical homeostasis GO:0055082 17 0.037
response to glucose GO:0009749 3 0.037
cellular localization GO:0051641 97 0.037
divalent inorganic cation homeostasis GO:0072507 22 0.037
regulation of nucleotide catabolic process GO:0030811 2 0.036
protein import GO:0017038 3 0.036
regeneration GO:0031099 91 0.036
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.036
regulation of neurotransmitter transport GO:0051588 1 0.036
cytoplasm organization GO:0007028 4 0.036
neuron differentiation GO:0030182 353 0.036
Fly
response to topologically incorrect protein GO:0035966 2 0.036
response to unfolded protein GO:0006986 2 0.036
muscle cell differentiation GO:0042692 139 0.036
neuroblast proliferation GO:0007405 2 0.035
ion homeostasis GO:0050801 41 0.035
carbohydrate derivative metabolic process GO:1901135 61 0.034
outflow tract morphogenesis GO:0003151 1 0.034
regulation of reactive oxygen species metabolic process GO:2000377 2 0.034
golgi vesicle transport GO:0048193 3 0.034
gastrulation with mouth forming second GO:0001702 44 0.034
microtubule organizing center organization GO:0031023 1 0.034
cortical actin cytoskeleton organization GO:0030866 1 0.033
regulation of binding GO:0051098 3 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
vesicle localization GO:0051648 27 0.033
protein complex disassembly GO:0043241 1 0.033
regulation of leukocyte mediated immunity GO:0002703 1 0.033
cellular carbohydrate metabolic process GO:0044262 4 0.033
ubiquitin dependent protein catabolic process GO:0006511 3 0.033
regulation of response to nutrient levels GO:0032107 1 0.033
cellular amino acid metabolic process GO:0006520 7 0.032
cellular response to biotic stimulus GO:0071216 3 0.032
female meiotic division GO:0007143 2 0.032
oxoacid metabolic process GO:0043436 31 0.032
rna localization GO:0006403 4 0.032
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.032
stem cell division GO:0017145 1 0.032
response to carbohydrate GO:0009743 3 0.031
response to hormone GO:0009725 48 0.031
leukocyte differentiation GO:0002521 25 0.031
positive regulation of jnk cascade GO:0046330 3 0.031
cell part morphogenesis GO:0032990 246 0.031
somite development GO:0061053 96 0.031
cellular ketone metabolic process GO:0042180 11 0.031
synaptic vesicle endocytosis GO:0048488 1 0.031
sexual reproduction GO:0019953 36 0.031
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.031
negative regulation of cell communication GO:0010648 96 0.031
positive regulation of immune system process GO:0002684 17 0.030
neuron projection development GO:0031175 180 0.030
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.030
blood vessel development GO:0001568 246 0.030
response to oxygen containing compound GO:1901700 55 0.030
cellular response to stress GO:0033554 62 0.030
positive regulation of protein complex assembly GO:0031334 2 0.030
regulation of exocytosis GO:0017157 1 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.030
peptidyl serine phosphorylation GO:0018105 1 0.030
chordate embryonic development GO:0043009 271 0.030
positive regulation of metabolic process GO:0009893 108 0.030
hormone mediated signaling pathway GO:0009755 9 0.030
regulation of synaptic vesicle transport GO:1902803 1 0.029
single organism nuclear import GO:1902593 3 0.029
regulation of dendrite morphogenesis GO:0048814 3 0.029
intracellular signal transduction GO:0035556 85 0.029
Mouse Fly
purine nucleotide metabolic process GO:0006163 27 0.029
regulation of sodium ion transport GO:0002028 2 0.029
negative regulation of programmed cell death GO:0043069 58 0.029
organic acid metabolic process GO:0006082 31 0.029
regulation of synaptic plasticity GO:0048167 1 0.029
axon regeneration GO:0031103 14 0.029
mononuclear cell proliferation GO:0032943 1 0.028
regulation of jak stat cascade GO:0046425 3 0.028
Fly
centrosome cycle GO:0007098 1 0.028
endoplasmic reticulum unfolded protein response GO:0030968 2 0.028
regulation of signaling GO:0023051 235 0.028
Fly
behavior GO:0007610 74 0.028
Fly
cellular pigmentation GO:0033059 30 0.028
tissue remodeling GO:0048771 4 0.028
cellular response to hormone stimulus GO:0032870 39 0.028
regulation of chemotaxis GO:0050920 18 0.028
stem cell development GO:0048864 82 0.028
Fly
nucleobase containing small molecule metabolic process GO:0055086 32 0.028
reactive oxygen species metabolic process GO:0072593 6 0.028
blastoderm segmentation GO:0007350 6 0.027
Fly
cellular cation homeostasis GO:0030003 17 0.027
positive regulation of wound healing GO:0090303 1 0.027
regulation of growth GO:0040008 42 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
cellular response to topologically incorrect protein GO:0035967 2 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
nuclear import GO:0051170 3 0.027
regulation of cell activation GO:0050865 1 0.027
negative regulation of intracellular transport GO:0032387 3 0.027
regulation of neurogenesis GO:0050767 87 0.027
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.027
determination of left right symmetry GO:0007368 179 0.026
response to monosaccharide GO:0034284 3 0.026
axon development GO:0061564 166 0.026
lamellipodium organization GO:0097581 1 0.026
regulation of hormone secretion GO:0046883 2 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
pole plasm assembly GO:0007315 4 0.026
phagocytosis engulfment GO:0006911 1 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
organophosphate metabolic process GO:0019637 37 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
protein targeting to nucleus GO:0044744 3 0.026
protein targeting to vacuole GO:0006623 1 0.026
lateral line development GO:0048882 66 0.025
regulation of response to oxidative stress GO:1902882 2 0.025
regulation of ion transport GO:0043269 22 0.025
cellular response to external stimulus GO:0071496 2 0.025
response to lipid GO:0033993 60 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
lymphocyte proliferation GO:0046651 1 0.025
cellular response to starvation GO:0009267 1 0.025
epidermis development GO:0008544 48 0.024
cellular component disassembly GO:0022411 1 0.024
metal ion homeostasis GO:0055065 26 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
somitogenesis GO:0001756 87 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
mitochondrial transport GO:0006839 2 0.024
lamellipodium assembly GO:0030032 1 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.024
protein localization to plasma membrane GO:0072659 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
response to ketone GO:1901654 1 0.024
nucleic acid transport GO:0050657 2 0.023
positive regulation of blood circulation GO:1903524 2 0.023
mitochondrion organization GO:0007005 4 0.023
myeloid cell differentiation GO:0030099 86 0.023
insulin like growth factor receptor signaling pathway GO:0048009 4 0.023
sensory perception of chemical stimulus GO:0007606 3 0.023
regulation of muscle contraction GO:0006937 3 0.023
protein polymerization GO:0051258 4 0.023
response to bacterium GO:0009617 58 0.023
regulation of intracellular signal transduction GO:1902531 57 0.023
Fly
establishment of protein localization to vacuole GO:0072666 1 0.023
activation of mapk activity GO:0000187 3 0.023
regulation of protein binding GO:0043393 3 0.023
response to antibiotic GO:0046677 1 0.023
Human
negative regulation of neuron projection regeneration GO:0070571 4 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
peptidyl tyrosine modification GO:0018212 5 0.023
Human Mouse
ribonucleotide metabolic process GO:0009259 27 0.023
organic substance transport GO:0071702 58 0.023
cellular response to nutrient levels GO:0031669 2 0.023
brain development GO:0007420 293 0.023
response to endogenous stimulus GO:0009719 83 0.022
peptide transport GO:0015833 1 0.022
macromolecular complex disassembly GO:0032984 1 0.022
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.022
response to growth factor GO:0070848 39 0.022
axonogenesis GO:0007409 152 0.022
protein localization to nucleus GO:0034504 3 0.022
membrane lipid biosynthetic process GO:0046467 2 0.022
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
hepaticobiliary system development GO:0061008 98 0.022
regulation of phosphorus metabolic process GO:0051174 43 0.022
cellular catabolic process GO:0044248 27 0.022
negative regulation of cellular biosynthetic process GO:0031327 55 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
Fly
regulation of protein polymerization GO:0032271 2 0.022
hormone transport GO:0009914 2 0.022
muscle cell migration GO:0014812 4 0.022
regulation of cell development GO:0060284 100 0.022
taxis GO:0042330 109 0.022
mechanosensory lateral line system development GO:0048881 49 0.022
regulation of inflammatory response GO:0050727 2 0.022
central nervous system development GO:0007417 387 0.022
tyrosine phosphorylation of stat protein GO:0007260 1 0.022
stem cell maintenance GO:0019827 4 0.022
Fly
positive regulation of protein kinase b signaling GO:0051897 1 0.022
divalent inorganic cation transport GO:0072511 21 0.021
cellular response to unfolded protein GO:0034620 2 0.021
liver development GO:0001889 96 0.021
regulation of dendrite development GO:0050773 3 0.021
regulation of reproductive process GO:2000241 4 0.021
regulation of signal transduction GO:0009966 225 0.021
Fly
negative regulation of chemotaxis GO:0050922 4 0.021
head development GO:0060322 303 0.021
regulation of synapse organization GO:0050807 3 0.021
centrosome organization GO:0051297 1 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.021
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
regulation of synapse assembly GO:0051963 3 0.021
immune response GO:0006955 28 0.020
regulation of molecular function GO:0065009 70 0.020
regulation of protein catabolic process GO:0042176 1 0.020
organelle localization GO:0051640 49 0.020
positive regulation of catabolic process GO:0009896 4 0.020
multicellular organism reproduction GO:0032504 35 0.020
Fly
hormone secretion GO:0046879 2 0.020
positive regulation of rna biosynthetic process GO:1902680 57 0.020
regulation of wound healing GO:0061041 2 0.020
single organism behavior GO:0044708 24 0.020
Fly
protein stabilization GO:0050821 2 0.020
cellular component biogenesis GO:0044085 178 0.020

jak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
organ system cancer DOID:0050686 0 0.046
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.021