Danio rerio

0 known processes

kars

lysyl-tRNA synthetase

(Aliases: cb530,wu:fa16h02,zgc:92483)

kars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
biosynthetic process GO:0009058 294 0.701
Human
larval development GO:0002164 2 0.640
Worm
gene expression GO:0010467 252 0.566
Human
cellular biosynthetic process GO:0044249 286 0.539
Human
cellular macromolecule metabolic process GO:0044260 391 0.524
Human
macromolecule biosynthetic process GO:0009059 227 0.455
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.443
nucleic acid metabolic process GO:0090304 244 0.418
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.396
Human
regulation of macromolecule metabolic process GO:0060255 317 0.387
regulation of gene expression GO:0010468 265 0.344
positive regulation of biological process GO:0048518 253 0.309
Worm
regulation of multicellular organismal process GO:0051239 277 0.296
Worm
regulation of primary metabolic process GO:0080090 311 0.294
protein metabolic process GO:0019538 183 0.292
Human
head development GO:0060322 303 0.263
translational initiation GO:0006413 3 0.230
embryo development ending in birth or egg hatching GO:0009792 271 0.202
Worm
organic substance biosynthetic process GO:1901576 289 0.194
Human
locomotion GO:0040011 313 0.181
heterocycle biosynthetic process GO:0018130 215 0.174
regulation of biosynthetic process GO:0009889 250 0.171
regulation of cellular metabolic process GO:0031323 320 0.167
negative regulation of cellular process GO:0048523 283 0.162
negative regulation of biological process GO:0048519 304 0.157
central nervous system development GO:0007417 387 0.138
regulation of metabolic process GO:0019222 359 0.136
regulation of developmental process GO:0050793 247 0.136
Worm
lipid storage GO:0019915 1 0.129
cellular nitrogen compound metabolic process GO:0034641 290 0.126
Human
aging GO:0007568 2 0.125
small molecule metabolic process GO:0044281 77 0.121
Human
transcription dna templated GO:0006351 181 0.106
nitrogen compound metabolic process GO:0006807 319 0.106
Human
regulation of translational initiation GO:0006446 1 0.103
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.101
cell death GO:0008219 121 0.097
organic cyclic compound biosynthetic process GO:1901362 223 0.095
translation GO:0006412 5 0.092
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.092
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.089
regulation of cellular biosynthetic process GO:0031326 245 0.078
cellular protein metabolic process GO:0044267 129 0.077
Human
organic cyclic compound metabolic process GO:1901360 301 0.077
Human
rna biosynthetic process GO:0032774 181 0.075
rna metabolic process GO:0016070 219 0.072
Human
cellular amino acid metabolic process GO:0006520 7 0.071
Human
brain development GO:0007420 293 0.071
regulation of multicellular organism growth GO:0040014 4 0.063
Worm
multicellular organism growth GO:0035264 4 0.059
Worm
regulation of proteolysis GO:0030162 24 0.058
regulation of protein metabolic process GO:0051246 56 0.057
ribosomal small subunit biogenesis GO:0042274 2 0.055
single organism metabolic process GO:0044710 217 0.055
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.053
heterocycle metabolic process GO:0046483 290 0.053
Human
regulation of cellular protein metabolic process GO:0032268 52 0.053
embryonic organ development GO:0048568 381 0.052
regulation of nucleic acid templated transcription GO:1903506 213 0.050
reproduction GO:0000003 40 0.048
Worm
regulation of programmed cell death GO:0043067 101 0.048
regulation of apoptotic process GO:0042981 98 0.048
regulation of biological quality GO:0065008 263 0.045
transport GO:0006810 220 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.043
Human
phosphorus metabolic process GO:0006793 109 0.043
response to abiotic stimulus GO:0009628 122 0.043
response to chemical GO:0042221 320 0.043
aromatic compound biosynthetic process GO:0019438 217 0.043
regulation of rna metabolic process GO:0051252 224 0.042
cellular aromatic compound metabolic process GO:0006725 295 0.041
Human
regulation of transcription dna templated GO:0006355 213 0.039
maintenance of location GO:0051235 4 0.039
apoptotic process GO:0006915 116 0.036
cell morphogenesis GO:0000902 289 0.035
positive regulation of translation GO:0045727 1 0.034
nucleic acid templated transcription GO:0097659 181 0.034
positive regulation of cellular biosynthetic process GO:0031328 68 0.034
system process GO:0003008 185 0.033
death GO:0016265 121 0.033
response to other organism GO:0051707 97 0.033
cellular amine metabolic process GO:0044106 2 0.033
cellular component morphogenesis GO:0032989 336 0.032
macromolecule modification GO:0043412 111 0.032
establishment of localization GO:0051234 244 0.031
organic acid metabolic process GO:0006082 31 0.030
Human
embryonic skeletal system morphogenesis GO:0048704 93 0.030
regulation of translation GO:0006417 3 0.029
programmed cell death GO:0012501 119 0.029
negative regulation of gene expression GO:0010629 65 0.028
regulation of signal transduction GO:0009966 225 0.028
embryonic cranial skeleton morphogenesis GO:0048701 90 0.027
eye development GO:0001654 277 0.027
cell part morphogenesis GO:0032990 246 0.026
positive regulation of cellular process GO:0048522 201 0.026
response to external stimulus GO:0009605 264 0.025
regulation of response to stimulus GO:0048583 269 0.025
chordate embryonic development GO:0043009 271 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
negative regulation of metabolic process GO:0009892 86 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
protein modification process GO:0036211 100 0.024
single organism localization GO:1902578 225 0.023
neuron projection morphogenesis GO:0048812 161 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
developmental growth GO:0048589 166 0.023
Worm
positive regulation of gtpase activity GO:0043547 1 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.021
neuron differentiation GO:0030182 353 0.021
negative regulation of apoptotic process GO:0043066 55 0.021
oxoacid metabolic process GO:0043436 31 0.021
Human
endocytosis GO:0006897 16 0.021
single organism biosynthetic process GO:0044711 71 0.021
camera type eye development GO:0043010 222 0.021
signal transduction GO:0007165 455 0.021
response to external biotic stimulus GO:0043207 97 0.020
response to stress GO:0006950 263 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
positive regulation of metabolic process GO:0009893 108 0.019
microtubule organizing center organization GO:0031023 1 0.019
fin regeneration GO:0031101 51 0.019
dna biosynthetic process GO:0071897 3 0.019
maturation of ssu rrna GO:0030490 1 0.019
embryonic skeletal system development GO:0048706 97 0.019
cell projection morphogenesis GO:0048858 244 0.018
cellular component disassembly GO:0022411 1 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
embryonic heart tube development GO:0035050 133 0.018
cell migration GO:0016477 237 0.018
transmembrane transport GO:0055085 120 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
protein acetylation GO:0006473 2 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
single organism organelle organization GO:1902589 199 0.016
response to biotic stimulus GO:0009607 97 0.016
phagocytosis GO:0006909 3 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
amine metabolic process GO:0009308 2 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
organelle localization GO:0051640 49 0.015
gtp catabolic process GO:0006184 2 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
nuclear export GO:0051168 1 0.015
single organism reproductive process GO:0044702 40 0.015
positive regulation of gene expression GO:0010628 71 0.015
carboxylic acid metabolic process GO:0019752 22 0.014
Human
response to virus GO:0009615 21 0.014
negative regulation of cell death GO:0060548 60 0.014
cell cycle GO:0007049 93 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
regulation of peptidase activity GO:0052547 23 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
tissue regeneration GO:0042246 74 0.014
phosphate containing compound metabolic process GO:0006796 108 0.013
ncrna metabolic process GO:0034660 12 0.013
Human
generation of neurons GO:0048699 385 0.013
regeneration GO:0031099 91 0.013
gamete generation GO:0007276 33 0.013
vasculature development GO:0001944 278 0.013
cellular component biogenesis GO:0044085 178 0.013
glial cell differentiation GO:0010001 42 0.013
organic acid transport GO:0015849 9 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
muscle structure development GO:0061061 196 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
protein acylation GO:0043543 3 0.012
organelle organization GO:0006996 227 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
multi organism process GO:0051704 134 0.011
regulation of cell communication GO:0010646 232 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
Worm
heart development GO:0007507 313 0.011
regulation of molecular function GO:0065009 70 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
sensory organ development GO:0007423 393 0.011
spindle assembly GO:0051225 2 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
regulation of gtpase activity GO:0043087 2 0.011
specification of symmetry GO:0009799 204 0.011
regulation of signaling GO:0023051 235 0.010
negative regulation of defense response GO:0031348 2 0.010
cell projection organization GO:0030030 284 0.010
positive regulation of developmental process GO:0051094 50 0.010
Worm
cell surface receptor signaling pathway GO:0007166 325 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010

kars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.077
neuromuscular disease DOID:440 0 0.029
charcot marie tooth disease type 2 DOID:0050539 0 0.029
charcot marie tooth disease DOID:10595 0 0.029
nervous system disease DOID:863 0 0.029
neuropathy DOID:870 0 0.029
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012