Danio rerio

11 known processes

klf4a

Kruppel-like transcription factor 4a

klf4a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biological process GO:0048519 304 0.952
regulation of rna metabolic process GO:0051252 224 0.910
cellular macromolecule metabolic process GO:0044260 391 0.853
regulation of macromolecule metabolic process GO:0060255 317 0.825
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.804
regulation of primary metabolic process GO:0080090 311 0.730
regulation of cellular biosynthetic process GO:0031326 245 0.696
nucleic acid templated transcription GO:0097659 181 0.693
embryonic organ morphogenesis GO:0048562 274 0.654
organic cyclic compound metabolic process GO:1901360 301 0.641
regulation of nitrogen compound metabolic process GO:0051171 251 0.616
cellular biosynthetic process GO:0044249 286 0.606
regulation of metabolic process GO:0019222 359 0.584
gene expression GO:0010467 252 0.571
cellular nitrogen compound biosynthetic process GO:0044271 218 0.554
heart development GO:0007507 313 0.543
macromolecule biosynthetic process GO:0009059 227 0.538
heterocycle metabolic process GO:0046483 290 0.527
cell surface receptor signaling pathway GO:0007166 325 0.509
rna biosynthetic process GO:0032774 181 0.504
blood vessel development GO:0001568 246 0.485
regulation of multicellular organismal process GO:0051239 277 0.474
regulation of macromolecule biosynthetic process GO:0010556 225 0.472
positive regulation of cellular process GO:0048522 201 0.471
chordate embryonic development GO:0043009 271 0.463
regulation of gene expression GO:0010468 265 0.463
apoptotic process GO:0006915 116 0.460
regulation of nucleic acid templated transcription GO:1903506 213 0.446
regulation of cellular metabolic process GO:0031323 320 0.420
cellular aromatic compound metabolic process GO:0006725 295 0.417
cellular macromolecule biosynthetic process GO:0034645 224 0.417
regulation of signal transduction GO:0009966 225 0.405
regulation of rna biosynthetic process GO:2001141 213 0.404
system process GO:0003008 185 0.401
embryonic organ development GO:0048568 381 0.400
positive regulation of biological process GO:0048518 253 0.366
nitrogen compound metabolic process GO:0006807 319 0.364
positive regulation of striated muscle tissue development GO:0045844 1 0.352
positive regulation of muscle organ development GO:0048636 1 0.351
vasculature development GO:0001944 278 0.351
embryonic heart tube development GO:0035050 133 0.342
determination of heart left right asymmetry GO:0061371 117 0.339
regulation of neuron migration GO:2001222 2 0.338
anterior posterior pattern specification GO:0009952 152 0.335
regulation of developmental process GO:0050793 247 0.330
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.324
signal transduction GO:0007165 455 0.290
rna metabolic process GO:0016070 219 0.286
nucleic acid metabolic process GO:0090304 244 0.280
response to corticosteroid GO:0031960 1 0.277
organic cyclic compound biosynthetic process GO:1901362 223 0.272
morphogenesis of an epithelium GO:0002009 333 0.271
regulation of transcription dna templated GO:0006355 213 0.271
ameboidal type cell migration GO:0001667 143 0.270
regionalization GO:0003002 274 0.263
regulation of dna templated transcription in response to stress GO:0043620 0 0.261
cellular component morphogenesis GO:0032989 336 0.255
response to drug GO:0042493 3 0.241
embryonic heart tube morphogenesis GO:0003143 108 0.240
skeletal muscle organ development GO:0060538 78 0.235
negative regulation of rna metabolic process GO:0051253 48 0.233
aromatic compound biosynthetic process GO:0019438 217 0.233
bmp signaling pathway GO:0030509 52 0.231
death GO:0016265 121 0.226
larval development GO:0002164 2 0.224
regulation of cell communication GO:0010646 232 0.220
negative regulation of developmental process GO:0051093 65 0.217
regulation of biological quality GO:0065008 263 0.217
regulation of multicellular organismal development GO:2000026 223 0.215
localization of cell GO:0051674 244 0.213
positive regulation of signaling GO:0023056 56 0.211
organic substance biosynthetic process GO:1901576 289 0.209
retina development in camera type eye GO:0060041 146 0.206
embryo development ending in birth or egg hatching GO:0009792 271 0.202
biosynthetic process GO:0009058 294 0.200
transcription dna templated GO:0006351 181 0.198
response to light stimulus GO:0009416 46 0.196
enzyme linked receptor protein signaling pathway GO:0007167 106 0.194
cellular nitrogen compound metabolic process GO:0034641 290 0.192
camera type eye development GO:0043010 222 0.191
regulation of cardiac muscle tissue development GO:0055024 1 0.191
positive regulation of multicellular organismal process GO:0051240 52 0.189
regulation of biosynthetic process GO:0009889 250 0.185
nucleobase containing compound metabolic process GO:0006139 274 0.185
striated muscle tissue development GO:0014706 110 0.184
regulation of cell differentiation GO:0045595 142 0.182
cellular response to nutrient levels GO:0031669 2 0.178
epithelial cell differentiation GO:0030855 116 0.178
pectoral fin development GO:0033339 50 0.177
retina morphogenesis in camera type eye GO:0060042 79 0.177
muscle cell differentiation GO:0042692 139 0.176
skeletal system development GO:0001501 181 0.172
nucleobase containing compound biosynthetic process GO:0034654 205 0.170
muscle tissue development GO:0060537 110 0.170
heterocycle biosynthetic process GO:0018130 215 0.169
cell migration GO:0016477 237 0.165
multicellular organism growth GO:0035264 4 0.162
regulation of skeletal muscle tissue development GO:0048641 4 0.162
fin development GO:0033333 77 0.158
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.158
ear development GO:0043583 127 0.158
hepaticobiliary system development GO:0061008 98 0.158
positive regulation of apoptotic process GO:0043065 29 0.157
positive regulation of nucleic acid templated transcription GO:1903508 57 0.153
locomotion GO:0040011 313 0.152
response to inorganic substance GO:0010035 38 0.151
regulation of synaptic plasticity GO:0048167 1 0.151
regulation of cellular component movement GO:0051270 55 0.149
astrocyte differentiation GO:0048708 1 0.149
response to chemical GO:0042221 320 0.146
response to stress GO:0006950 263 0.146
digestive tract development GO:0048565 265 0.143
cell fate commitment GO:0045165 99 0.142
positive regulation of cellular catabolic process GO:0031331 3 0.141
sensory organ morphogenesis GO:0090596 200 0.141
determination of bilateral symmetry GO:0009855 204 0.141
regulation of apoptotic process GO:0042981 98 0.140
programmed cell death GO:0012501 119 0.135
g protein coupled receptor signaling pathway GO:0007186 74 0.132
response to external stimulus GO:0009605 264 0.132
cellular response to organic substance GO:0071310 105 0.130
regulation of heart growth GO:0060420 2 0.130
positive regulation of cellular metabolic process GO:0031325 94 0.129
heart looping GO:0001947 94 0.128
oxidation reduction process GO:0055114 41 0.127
regulation of epithelial cell proliferation GO:0050678 3 0.125
regulation of cell proliferation GO:0042127 37 0.124
negative regulation of multicellular organismal process GO:0051241 69 0.124
heart morphogenesis GO:0003007 156 0.123
muscle structure development GO:0061061 196 0.117
regulation of response to stimulus GO:0048583 269 0.117
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.116
skeletal system morphogenesis GO:0048705 102 0.116
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.114
cellular response to oxygen levels GO:0071453 1 0.114
regulation of cell development GO:0060284 100 0.111
blood vessel morphogenesis GO:0048514 216 0.110
regulation of cytoplasmic transport GO:1903649 4 0.109
segmentation GO:0035282 97 0.108
steroid hormone mediated signaling pathway GO:0043401 9 0.107
skeletal muscle tissue development GO:0007519 67 0.106
inner ear development GO:0048839 126 0.106
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.104
xenobiotic metabolic process GO:0006805 4 0.104
striated muscle cell differentiation GO:0051146 129 0.104
growth GO:0040007 174 0.103
cellular response to external stimulus GO:0071496 2 0.101
positive regulation of cell cycle GO:0045787 3 0.100
protein localization to nucleus GO:0034504 3 0.099
embryonic skeletal system development GO:0048706 97 0.099
positive regulation of macromolecule metabolic process GO:0010604 93 0.098
cell morphogenesis GO:0000902 289 0.097
regulation of cell division GO:0051302 12 0.096
glial cell migration GO:0008347 3 0.095
striated muscle cell development GO:0055002 108 0.095
regulation of cell death GO:0010941 103 0.094
circulatory system process GO:0003013 87 0.094
generation of neurons GO:0048699 385 0.093
positive regulation of gene expression GO:0010628 71 0.092
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.091
positive regulation of cell death GO:0010942 29 0.091
liver development GO:0001889 96 0.090
organelle organization GO:0006996 227 0.090
endocardial cushion formation GO:0003272 2 0.090
regulation of cell size GO:0008361 29 0.090
female sex differentiation GO:0046660 4 0.090
mesenchyme development GO:0060485 127 0.088
positive regulation of muscle tissue development GO:1901863 1 0.088
cell cycle GO:0007049 93 0.088
regulation of anatomical structure morphogenesis GO:0022603 130 0.085
cellular response to chemical stimulus GO:0070887 157 0.085
response to other organism GO:0051707 97 0.084
regulation of signaling GO:0023051 235 0.084
establishment of localization GO:0051234 244 0.084
guanosine containing compound catabolic process GO:1901069 2 0.084
kidney development GO:0001822 92 0.083
regulation of locomotion GO:0040012 55 0.083
angiogenesis GO:0001525 158 0.083
positive regulation of cellular biosynthetic process GO:0031328 68 0.082
cell fate specification GO:0001708 68 0.081
negative regulation of bmp signaling pathway GO:0030514 13 0.081
regulation of multicellular organism growth GO:0040014 4 0.079
regulation of organ growth GO:0046620 3 0.079
eye development GO:0001654 277 0.079
gliogenesis GO:0042063 45 0.078
regulation of nervous system development GO:0051960 90 0.077
regulation of developmental growth GO:0048638 38 0.077
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.077
immune system development GO:0002520 191 0.076
cell death GO:0008219 121 0.075
regulation of neurogenesis GO:0050767 87 0.075
lipid oxidation GO:0034440 1 0.074
appendage development GO:0048736 80 0.074
skin development GO:0043588 54 0.073
foregut morphogenesis GO:0007440 4 0.073
kidney vasculature development GO:0061440 2 0.073
response to metal ion GO:0010038 34 0.073
regulation of stem cell differentiation GO:2000736 4 0.072
negative regulation of stem cell differentiation GO:2000737 2 0.071
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.071
negative regulation of macromolecule metabolic process GO:0010605 76 0.071
cellular response to growth factor stimulus GO:0071363 39 0.070
aging GO:0007568 2 0.070
cell motility GO:0048870 244 0.070
auditory receptor cell fate commitment GO:0009912 4 0.070
negative regulation of cellular process GO:0048523 283 0.069
positive regulation of biosynthetic process GO:0009891 68 0.069
regulation of growth GO:0040008 42 0.069
regulation of localization GO:0032879 104 0.068
negative regulation of cell differentiation GO:0045596 46 0.068
regulation of inflammatory response GO:0050727 2 0.067
embryonic cranial skeleton morphogenesis GO:0048701 90 0.067
negative regulation of cellular metabolic process GO:0031324 77 0.067
negative regulation of rna biosynthetic process GO:1902679 45 0.067
glomerulus vasculature development GO:0072012 2 0.065
positive regulation of neuron apoptotic process GO:0043525 1 0.065
ectodermal placode morphogenesis GO:0071697 32 0.065
negative regulation of gene expression GO:0010629 65 0.065
intracellular signal transduction GO:0035556 85 0.065
negative regulation of biosynthetic process GO:0009890 55 0.064
lateral line system development GO:0048925 76 0.064
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.064
cellular component movement GO:0006928 335 0.063
maintenance of location GO:0051235 4 0.063
mitochondrion organization GO:0007005 4 0.063
cellular response to starvation GO:0009267 1 0.062
sensory organ development GO:0007423 393 0.062
embryonic skeletal joint morphogenesis GO:0060272 3 0.061
transcription from rna polymerase ii promoter GO:0006366 80 0.061
connective tissue development GO:0061448 99 0.060
negative regulation of metabolic process GO:0009892 86 0.060
developmental programmed cell death GO:0010623 4 0.059
regulation of protein localization to nucleus GO:1900180 2 0.058
phosphate containing compound metabolic process GO:0006796 108 0.058
regulation of muscle organ development GO:0048634 9 0.058
negative regulation of map kinase activity GO:0043407 2 0.057
response to external biotic stimulus GO:0043207 97 0.057
epithelial cell development GO:0002064 42 0.057
canonical wnt signaling pathway GO:0060070 48 0.056
regulation of bmp signaling pathway GO:0030510 39 0.056
blood circulation GO:0008015 87 0.056
response to radiation GO:0009314 51 0.055
cellular response to radiation GO:0071478 4 0.055
negative regulation of signaling GO:0023057 96 0.055
compound eye development GO:0048749 2 0.055
embryonic skeletal system morphogenesis GO:0048704 93 0.054
positive regulation of embryonic development GO:0040019 3 0.054
regulation of blood circulation GO:1903522 32 0.053
positive regulation of cellular component movement GO:0051272 11 0.052
regulation of axon guidance GO:1902667 8 0.052
positive regulation of developmental process GO:0051094 50 0.052
protein metabolic process GO:0019538 183 0.052
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.051
positive regulation of catabolic process GO:0009896 4 0.051
regulation of protein transport GO:0051223 3 0.051
regulation of programmed cell death GO:0043067 101 0.050
negative regulation of nucleic acid templated transcription GO:1903507 45 0.050
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.050
positive regulation of cell development GO:0010720 25 0.050
somite development GO:0061053 96 0.049
response to organic substance GO:0010033 153 0.049
regulation of reproductive process GO:2000241 4 0.048
somitogenesis GO:0001756 87 0.048
negative regulation of cell communication GO:0010648 96 0.048
cellular hormone metabolic process GO:0034754 19 0.048
homeostatic process GO:0042592 142 0.048
camera type eye morphogenesis GO:0048593 108 0.048
notochord development GO:0030903 54 0.047
neural retina development GO:0003407 49 0.047
cell morphogenesis involved in differentiation GO:0000904 195 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.047
meiotic nuclear division GO:0007126 4 0.047
apoptotic process involved in development GO:1902742 2 0.046
neuron fate commitment GO:0048663 26 0.046
guanosine containing compound metabolic process GO:1901068 4 0.046
negative regulation of programmed cell death GO:0043069 58 0.046
central nervous system development GO:0007417 387 0.046
epidermis development GO:0008544 48 0.045
digestive system development GO:0055123 289 0.045
hormone transport GO:0009914 2 0.045
positive regulation of cell communication GO:0010647 56 0.045
wnt signaling pathway GO:0016055 80 0.044
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.044
positive regulation of protein complex assembly GO:0031334 2 0.044
cellular response to hypoxia GO:0071456 1 0.044
regulation of cell motility GO:2000145 46 0.043
cellular response to extracellular stimulus GO:0031668 2 0.043
response to growth factor GO:0070848 39 0.043
cardiocyte differentiation GO:0035051 44 0.043
trabecula morphogenesis GO:0061383 2 0.043
negative regulation of signal transduction GO:0009968 94 0.043
regulation of gastrulation GO:0010470 24 0.042
wound healing GO:0042060 90 0.042
regulation of oligodendrocyte differentiation GO:0048713 1 0.042
determination of dorsal ventral asymmetry GO:0048262 34 0.042
regulation of cell migration GO:0030334 40 0.042
cardiac muscle cell development GO:0055013 20 0.041
positive regulation of transport GO:0051050 2 0.041
negative regulation of protein kinase activity GO:0006469 4 0.041
regulation of molecular function GO:0065009 70 0.041
endocardial cell differentiation GO:0060956 5 0.041
i kappab kinase nf kappab signaling GO:0007249 4 0.040
cellular response to decreased oxygen levels GO:0036294 1 0.040
gtp metabolic process GO:0046039 4 0.040
neuron death GO:0070997 21 0.040
post embryonic organ development GO:0048569 4 0.040
negative regulation of transcription dna templated GO:0045892 45 0.040
cell projection organization GO:0030030 284 0.040
positive regulation of protein polymerization GO:0032273 2 0.040
regulation of axon extension GO:0030516 24 0.040
negative regulation of sequestering of calcium ion GO:0051283 4 0.039
gtp catabolic process GO:0006184 2 0.039
regulation of dendrite morphogenesis GO:0048814 3 0.039
response to decreased oxygen levels GO:0036293 25 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.038
keratinocyte differentiation GO:0030216 0 0.038
negative regulation of apoptotic process GO:0043066 55 0.038
specification of symmetry GO:0009799 204 0.038
fin morphogenesis GO:0033334 53 0.037
negative regulation of molecular function GO:0044092 23 0.037
lipid catabolic process GO:0016042 4 0.037
response to abiotic stimulus GO:0009628 122 0.037
regulation of cell fate commitment GO:0010453 22 0.037
single organism localization GO:1902578 225 0.036
rhythmic process GO:0048511 21 0.036
cellular carbohydrate metabolic process GO:0044262 4 0.036
regulation of protein catabolic process GO:0042176 1 0.036
response to nutrient levels GO:0031667 10 0.036
positive regulation of rna biosynthetic process GO:1902680 57 0.036
positive regulation of metabolic process GO:0009893 108 0.036
glial cell differentiation GO:0010001 42 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
response to transition metal nanoparticle GO:1990267 28 0.035
regulation of circadian rhythm GO:0042752 4 0.035
hormone secretion GO:0046879 2 0.035
pancreas development GO:0031016 84 0.035
dorsal ventral pattern formation GO:0009953 125 0.035
regulation of gtpase activity GO:0043087 2 0.035
single organism transport GO:0044765 206 0.035
cell cell signaling GO:0007267 52 0.034
positive regulation of neuron death GO:1901216 1 0.034
cellular protein modification process GO:0006464 100 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.034
regulation of reactive oxygen species metabolic process GO:2000377 2 0.033
regulation of intracellular protein transport GO:0033157 3 0.033
regulation of protein complex assembly GO:0043254 3 0.033
developmental growth GO:0048589 166 0.033
neurological system process GO:0050877 62 0.033
cell part morphogenesis GO:0032990 246 0.033
developmental growth involved in morphogenesis GO:0060560 86 0.032
positive regulation of transcription dna templated GO:0045893 57 0.032
hindbrain development GO:0030902 91 0.032
protein import GO:0017038 3 0.032
response to xenobiotic stimulus GO:0009410 45 0.032
positive regulation of signal transduction GO:0009967 56 0.032
negative regulation of secretion GO:0051048 2 0.032
stem cell division GO:0017145 1 0.032
myeloid cell differentiation GO:0030099 86 0.032
renal system development GO:0072001 94 0.031
small molecule metabolic process GO:0044281 77 0.031
actin cytoskeleton organization GO:0030036 63 0.031
gland development GO:0048732 143 0.031
regulation of cell cycle GO:0051726 52 0.031
negative regulation of reproductive process GO:2000242 3 0.031
ectodermal placode formation GO:0060788 26 0.031
regulation of striated muscle tissue development GO:0016202 6 0.031
determination of left right symmetry GO:0007368 179 0.030
regulation of anatomical structure size GO:0090066 33 0.030
regulation of hormone levels GO:0010817 21 0.030
mesenchymal cell differentiation GO:0048762 87 0.030
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
dorsal convergence GO:0060030 14 0.030
regulation of phosphate metabolic process GO:0019220 43 0.030
transport GO:0006810 220 0.029
muscle cell development GO:0055001 115 0.029
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.029
phosphorus metabolic process GO:0006793 109 0.029
carbohydrate biosynthetic process GO:0016051 1 0.029
cartilage development GO:0051216 96 0.029
cell growth GO:0016049 57 0.029
epithelial tube morphogenesis GO:0060562 148 0.028
heart process GO:0003015 71 0.028
digestive tract mesoderm development GO:0007502 1 0.028
negative regulation of catalytic activity GO:0043086 21 0.028
negative regulation of gastrulation GO:2000542 11 0.028
cardiac cell fate commitment GO:0060911 1 0.027
cartilage condensation GO:0001502 3 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.027
single organism cellular localization GO:1902580 46 0.027
cellular ketone metabolic process GO:0042180 11 0.027
response to alkaloid GO:0043279 2 0.026
otic vesicle development GO:0071599 42 0.026
microtubule cytoskeleton organization GO:0000226 33 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
renal system vasculature development GO:0061437 2 0.026
cell migration involved in gastrulation GO:0042074 79 0.025
defense response to bacterium GO:0042742 22 0.025
single organism metabolic process GO:0044710 217 0.025
antimicrobial humoral response GO:0019730 2 0.025
ear morphogenesis GO:0042471 64 0.025
regulation of embryonic development GO:0045995 47 0.025
endodermal digestive tract morphogenesis GO:0061031 2 0.025
diencephalon development GO:0021536 58 0.025
regulation of wnt signaling pathway GO:0030111 53 0.025
macromolecule modification GO:0043412 111 0.025
epithalamus development GO:0021538 10 0.025
protein localization GO:0008104 40 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
brain development GO:0007420 293 0.024
regulation of behavior GO:0050795 24 0.024
axonogenesis involved in innervation GO:0060385 1 0.024
post anal tail morphogenesis GO:0036342 19 0.024
reactive oxygen species metabolic process GO:0072593 6 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
mesoderm development GO:0007498 88 0.024
pharyngeal system development GO:0060037 18 0.024
formation of primary germ layer GO:0001704 62 0.023
regulation of cell activation GO:0050865 1 0.023
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.023
energy reserve metabolic process GO:0006112 2 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
negative regulation of cell fate commitment GO:0010454 13 0.023
cardiac cell development GO:0055006 21 0.023
cognition GO:0050890 1 0.023
chemical homeostasis GO:0048878 49 0.023
sensory perception of pain GO:0019233 1 0.023
negative regulation of cell fate specification GO:0009996 11 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
neural crest cell development GO:0014032 62 0.022
endocardial cushion morphogenesis GO:0003203 3 0.022
hormone mediated signaling pathway GO:0009755 9 0.022
positive regulation of locomotion GO:0040017 14 0.022
response to wounding GO:0009611 116 0.022
heart contraction GO:0060047 71 0.022
positive regulation of neuron migration GO:2001224 2 0.022
female gonad development GO:0008585 4 0.022
neural crest cell differentiation GO:0014033 72 0.022
positive regulation of neuron projection development GO:0010976 9 0.022
cell type specific apoptotic process GO:0097285 22 0.022
negative regulation of locomotion GO:0040013 18 0.021
regulation of transport GO:0051049 45 0.021
response to organic cyclic compound GO:0014070 51 0.021
muscle organ development GO:0007517 101 0.021
cellular response to stress GO:0033554 62 0.021
cell maturation GO:0048469 23 0.021
single organism membrane fusion GO:0044801 2 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
regulation of organ morphogenesis GO:2000027 35 0.021
positive regulation of myeloid cell differentiation GO:0045639 2 0.021
calcium ion dependent exocytosis GO:0017156 1 0.021
endoderm development GO:0007492 49 0.021
phosphorylation GO:0016310 69 0.021
regulation of hormone secretion GO:0046883 2 0.020
cellular protein metabolic process GO:0044267 129 0.020
negative regulation of kinase activity GO:0033673 4 0.020
smooth muscle contraction GO:0006939 2 0.020
regulation of neurotransmitter transport GO:0051588 1 0.020
mesenchymal cell proliferation GO:0010463 1 0.020
negative regulation of protein localization to nucleus GO:1900181 2 0.020
tissue regeneration GO:0042246 74 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of dna replication GO:0006275 3 0.020
oligodendrocyte differentiation GO:0048709 23 0.019
negative regulation of feeding behavior GO:2000252 2 0.019
protein import into nucleus GO:0006606 3 0.019
neural tube development GO:0021915 62 0.019
establishment of localization in cell GO:0051649 77 0.019
cellular catabolic process GO:0044248 27 0.019
stem cell proliferation GO:0072089 4 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
hepatic duct development GO:0061011 2 0.019
embryonic camera type eye morphogenesis GO:0048596 19 0.019
cellular response to organic cyclic compound GO:0071407 38 0.019
embryonic skeletal joint development GO:0072498 3 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cytokinesis GO:0000910 3 0.018
cardiac conduction system development GO:0003161 1 0.018
posterior lateral line system development GO:0048915 46 0.018
single organism organelle organization GO:1902589 199 0.018
mesenchyme morphogenesis GO:0072132 5 0.018
peripheral nervous system development GO:0007422 55 0.018
response to oxygen levels GO:0070482 25 0.018
regulation of cellular component size GO:0032535 30 0.018
steroid metabolic process GO:0008202 7 0.018
autophagy GO:0006914 4 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018

klf4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
cardiovascular system disease DOID:1287 0 0.031
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.018
muscular disease DOID:0080000 0 0.018
cardiomyopathy DOID:0050700 0 0.018
myopathy DOID:423 0 0.018