Danio rerio

0 known processes

krcp

kelch repeat-containing protein

(Aliases: MGC123032,zgc:123032,wu:fi38d02,wu:fb97e08)

krcp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome cycle GO:0007098 1 0.578
centrosome organization GO:0051297 1 0.556
centrosome duplication GO:0051298 1 0.525
microtubule organizing center organization GO:0031023 1 0.493
g2 m transition of mitotic cell cycle GO:0000086 4 0.416
regulation of gene expression GO:0010468 265 0.310
cytokinesis GO:0000910 3 0.297
positive regulation of cell cycle GO:0045787 3 0.291
sensory organ development GO:0007423 393 0.266
mitotic cell cycle process GO:1903047 48 0.247
mitotic cell cycle GO:0000278 64 0.245
cell cycle g2 m phase transition GO:0044839 4 0.226
gene expression GO:0010467 252 0.225
regulation of cellular metabolic process GO:0031323 320 0.219
regulation of metabolic process GO:0019222 359 0.198
regulation of macromolecule metabolic process GO:0060255 317 0.195
cellular biosynthetic process GO:0044249 286 0.184
aging GO:0007568 2 0.175
multicellular organism growth GO:0035264 4 0.167
signal transduction GO:0007165 455 0.164
recombinational repair GO:0000725 1 0.142
positive regulation of cellular metabolic process GO:0031325 94 0.142
aromatic compound biosynthetic process GO:0019438 217 0.138
cellular macromolecule metabolic process GO:0044260 391 0.133
single organism metabolic process GO:0044710 217 0.133
cell cycle GO:0007049 93 0.133
macromolecule biosynthetic process GO:0009059 227 0.124
regulation of primary metabolic process GO:0080090 311 0.120
regulation of cell cycle GO:0051726 52 0.120
rna metabolic process GO:0016070 219 0.118
positive regulation of macromolecule metabolic process GO:0010604 93 0.102
regulation of multicellular organism growth GO:0040014 4 0.102
organic substance biosynthetic process GO:1901576 289 0.100
regulation of nucleic acid templated transcription GO:1903506 213 0.094
response to drug GO:0042493 3 0.092
cellular nitrogen compound biosynthetic process GO:0044271 218 0.087
digestive system development GO:0055123 289 0.087
chromosome organization GO:0051276 31 0.086
mitotic cell cycle embryonic GO:0045448 2 0.086
regulation of mitotic cell cycle GO:0007346 25 0.085
histone h3 k9 modification GO:0061647 5 0.084
cell cycle process GO:0022402 53 0.084
small molecule metabolic process GO:0044281 77 0.082
negative regulation of gene expression GO:0010629 65 0.082
positive regulation of biological process GO:0048518 253 0.080
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.079
regulation of cellular biosynthetic process GO:0031326 245 0.078
peptidyl serine phosphorylation GO:0018105 1 0.077
biosynthetic process GO:0009058 294 0.076
muscle cell differentiation GO:0042692 139 0.074
negative regulation of cell cycle process GO:0010948 9 0.074
protein metabolic process GO:0019538 183 0.073
cellular macromolecule biosynthetic process GO:0034645 224 0.072
organic cyclic compound biosynthetic process GO:1901362 223 0.071
central nervous system development GO:0007417 387 0.070
regulation of signaling GO:0023051 235 0.069
transcription dna templated GO:0006351 181 0.069
mitotic dna integrity checkpoint GO:0044774 4 0.068
positive regulation of transport GO:0051050 2 0.068
histone phosphorylation GO:0016572 2 0.065
double strand break repair via homologous recombination GO:0000724 1 0.064
regulation of rna metabolic process GO:0051252 224 0.063
cellular response to chemical stimulus GO:0070887 157 0.063
regulation of cell communication GO:0010646 232 0.062
transcription from rna polymerase ii promoter GO:0006366 80 0.062
regulation of response to stimulus GO:0048583 269 0.062
intracellular signal transduction GO:0035556 85 0.061
apoptotic process GO:0006915 116 0.060
embryonic hemopoiesis GO:0035162 53 0.060
reactive oxygen species metabolic process GO:0072593 6 0.058
response to endogenous stimulus GO:0009719 83 0.058
regulation of microtubule depolymerization GO:0031114 1 0.057
negative regulation of biological process GO:0048519 304 0.056
response to organic substance GO:0010033 153 0.055
cellular component disassembly GO:0022411 1 0.055
oocyte maturation GO:0001556 4 0.054
muscle structure development GO:0061061 196 0.054
peptidyl lysine dimethylation GO:0018027 1 0.054
anterior posterior pattern specification GO:0009952 152 0.053
wnt signaling pathway GO:0016055 80 0.053
locomotion GO:0040011 313 0.052
positive regulation of cellular process GO:0048522 201 0.052
localization of cell GO:0051674 244 0.052
programmed cell death GO:0012501 119 0.051
mitotic g2 m transition checkpoint GO:0044818 3 0.051
single organism organelle organization GO:1902589 199 0.051
nucleobase containing compound biosynthetic process GO:0034654 205 0.050
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
spindle assembly GO:0051225 2 0.049
mitotic nuclear division GO:0007067 18 0.048
embryo development ending in birth or egg hatching GO:0009792 271 0.047
regulation of multicellular organismal process GO:0051239 277 0.046
organic acid metabolic process GO:0006082 31 0.045
negative regulation of cellular process GO:0048523 283 0.045
transport GO:0006810 220 0.045
positive regulation of dna metabolic process GO:0051054 1 0.045
cellular amine metabolic process GO:0044106 2 0.044
regulation of signal transduction GO:0009966 225 0.044
cell division GO:0051301 20 0.044
mitotic sister chromatid segregation GO:0000070 6 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
carboxylic acid metabolic process GO:0019752 22 0.043
nitrogen compound metabolic process GO:0006807 319 0.043
hemopoiesis GO:0030097 183 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
positive regulation of metabolic process GO:0009893 108 0.042
organic cyclic compound metabolic process GO:1901360 301 0.041
cell morphogenesis GO:0000902 289 0.041
positive regulation of gene expression GO:0010628 71 0.041
response to chemical GO:0042221 320 0.040
regulation of transcription dna templated GO:0006355 213 0.040
negative regulation of apoptotic process GO:0043066 55 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
nucleic acid templated transcription GO:0097659 181 0.039
striated muscle cell differentiation GO:0051146 129 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.038
positive regulation of cell proliferation GO:0008284 15 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.038
positive regulation of catabolic process GO:0009896 4 0.038
double strand break repair GO:0006302 3 0.038
positive regulation of cellular biosynthetic process GO:0031328 68 0.038
phosphorylation GO:0016310 69 0.037
oxoacid metabolic process GO:0043436 31 0.037
organelle organization GO:0006996 227 0.037
g2 dna damage checkpoint GO:0031572 3 0.037
heterocycle metabolic process GO:0046483 290 0.037
amine metabolic process GO:0009308 2 0.037
microtubule based process GO:0007017 60 0.037
cellular nitrogen compound metabolic process GO:0034641 290 0.036
larval development GO:0002164 2 0.036
nuclear transport GO:0051169 4 0.036
regulation of meiotic cell cycle GO:0051445 1 0.036
cellular protein metabolic process GO:0044267 129 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
protein complex biogenesis GO:0070271 30 0.035
regulation of biosynthetic process GO:0009889 250 0.035
hematopoietic stem cell migration GO:0035701 4 0.035
cellular response to endogenous stimulus GO:0071495 68 0.034
muscle cell development GO:0055001 115 0.034
phosphate containing compound metabolic process GO:0006796 108 0.034
response to stress GO:0006950 263 0.034
regulation of rna biosynthetic process GO:2001141 213 0.033
regulation of chromosome segregation GO:0051983 1 0.033
regulation of programmed cell death GO:0043067 101 0.033
g1 s transition of mitotic cell cycle GO:0000082 1 0.033
regulation of cellular component organization GO:0051128 86 0.033
cellular response to external stimulus GO:0071496 2 0.033
head development GO:0060322 303 0.032
cell cycle phase transition GO:0044770 9 0.032
synapsis GO:0007129 1 0.032
negative regulation of cell cycle GO:0045786 14 0.032
cell cycle g1 s phase transition GO:0044843 1 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
organelle assembly GO:0070925 110 0.031
intracellular receptor signaling pathway GO:0030522 30 0.031
regulation of apoptotic process GO:0042981 98 0.031
negative regulation of developmental process GO:0051093 65 0.031
mitotic cell cycle phase transition GO:0044772 9 0.031
protein modification process GO:0036211 100 0.031
striated muscle cell development GO:0055002 108 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.030
peptidyl serine modification GO:0018209 2 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
regulation of developmental process GO:0050793 247 0.030
regulation of cell death GO:0010941 103 0.030
growth GO:0040007 174 0.029
cellular protein modification process GO:0006464 100 0.029
eye development GO:0001654 277 0.029
regulation of dna replication GO:0006275 3 0.029
protein polymerization GO:0051258 4 0.029
regulation of protein depolymerization GO:1901879 1 0.028
positive regulation of cell division GO:0051781 2 0.028
developmental growth GO:0048589 166 0.028
microtubule depolymerization GO:0007019 1 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
immune system process GO:0002376 241 0.028
regulation of dna templated transcription in response to stress GO:0043620 0 0.028
nucleic acid metabolic process GO:0090304 244 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
regulation of reactive oxygen species metabolic process GO:2000377 2 0.026
regulation of cell proliferation GO:0042127 37 0.026
establishment of localization GO:0051234 244 0.026
meiosis i GO:0007127 1 0.026
cell death GO:0008219 121 0.025
cellular response to oxygen levels GO:0071453 1 0.025
heart development GO:0007507 313 0.025
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.025
negative regulation of chromosome organization GO:2001251 1 0.025
cell migration GO:0016477 237 0.025
regulation of mitotic cell cycle phase transition GO:1901990 8 0.025
regulation of multicellular organismal development GO:2000026 223 0.024
golgi organization GO:0007030 1 0.024
tube morphogenesis GO:0035239 349 0.024
cell aging GO:0007569 2 0.024
cytoskeleton dependent cytokinesis GO:0061640 3 0.024
negative regulation of cell communication GO:0010648 96 0.024
single organism nuclear import GO:1902593 3 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
male meiosis GO:0007140 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
negative regulation of rna metabolic process GO:0051253 48 0.023
energy reserve metabolic process GO:0006112 2 0.023
protein targeting to nucleus GO:0044744 3 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
cellular component morphogenesis GO:0032989 336 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
macromolecule modification GO:0043412 111 0.022
cardiac atrium morphogenesis GO:0003209 2 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
compound eye development GO:0048749 2 0.022
positive regulation of chromosome organization GO:2001252 1 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of protein metabolic process GO:0051246 56 0.021
positive regulation of multicellular organismal process GO:0051240 52 0.021
cellular ketone metabolic process GO:0042180 11 0.020
regulation of biological quality GO:0065008 263 0.020
protein phosphorylation GO:0006468 47 0.020
negative regulation of nuclear division GO:0051784 3 0.020
regulation of wnt signaling pathway GO:0030111 53 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
nuclear migration GO:0007097 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
positive regulation of histone modification GO:0031058 1 0.020
erythrocyte differentiation GO:0030218 54 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
histone h3 k9 methylation GO:0051567 5 0.019
regulation of response to stress GO:0080134 36 0.019
camera type eye morphogenesis GO:0048593 108 0.018
dna catabolic process GO:0006308 1 0.018
regulation of cell cycle process GO:0010564 20 0.018
phosphorus metabolic process GO:0006793 109 0.018
positive regulation of rna biosynthetic process GO:1902680 57 0.018
sensory organ morphogenesis GO:0090596 200 0.018
regulation of phosphorylation GO:0042325 26 0.018
regulation of erythrocyte differentiation GO:0045646 2 0.018
cellular response to organic substance GO:0071310 105 0.018
response to wounding GO:0009611 116 0.018
spindle assembly involved in mitosis GO:0090307 1 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
stem cell development GO:0048864 82 0.018
regulation of molecular function GO:0065009 70 0.017
peptidyl threonine modification GO:0018210 1 0.017
stem cell differentiation GO:0048863 117 0.017
mitotic cytokinesis GO:0000281 3 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
immune system development GO:0002520 191 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
rna biosynthetic process GO:0032774 181 0.017
macromolecular complex disassembly GO:0032984 1 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of microtubule cytoskeleton organization GO:0070507 3 0.017
negative regulation of protein transport GO:0051224 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
cilium morphogenesis GO:0060271 85 0.017
specification of axis polarity GO:0065001 4 0.017
cellular component movement GO:0006928 335 0.017
negative regulation of cell death GO:0060548 60 0.017
cytoskeleton organization GO:0007010 96 0.017
regulation of cellular component movement GO:0051270 55 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
exocrine pancreas development GO:0031017 28 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
response to amine GO:0014075 1 0.016
organelle fusion GO:0048284 3 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
response to abiotic stimulus GO:0009628 122 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
regulation of protein binding GO:0043393 3 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
protein polyubiquitination GO:0000209 4 0.016
primary neural tube formation GO:0014020 1 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.016
regulation of cell cycle g2 m phase transition GO:1902749 4 0.016
negative regulation of kinase activity GO:0033673 4 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
wound healing GO:0042060 90 0.015
single organism biosynthetic process GO:0044711 71 0.015
protein depolymerization GO:0051261 1 0.015
dna biosynthetic process GO:0071897 3 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
mitotic dna damage checkpoint GO:0044773 4 0.015
negative regulation of signal transduction GO:0009968 94 0.015
cellular component assembly GO:0022607 170 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
dna metabolic process GO:0006259 27 0.015
cell cycle arrest GO:0007050 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
developmental maturation GO:0021700 34 0.015
heart valve formation GO:0003188 4 0.015
phagocytosis GO:0006909 3 0.015
cellular protein catabolic process GO:0044257 4 0.014
cyclic nucleotide biosynthetic process GO:0009190 18 0.014
regulation of circadian rhythm GO:0042752 4 0.014
stem cell maintenance GO:0019827 4 0.014
regulation of protein transport GO:0051223 3 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
positive regulation of cellular protein metabolic process GO:0032270 22 0.014
vasculature development GO:0001944 278 0.014
negative regulation of signaling GO:0023057 96 0.014
negative regulation of metabolic process GO:0009892 86 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
regulation of organelle organization GO:0033043 29 0.014
death GO:0016265 121 0.014
chromosome segregation GO:0007059 12 0.014
cell substrate adhesion GO:0031589 4 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
negative regulation of mitosis GO:0045839 3 0.014
negative regulation of mitotic cell cycle GO:0045930 11 0.013
histone modification GO:0016570 20 0.013
response to metal ion GO:0010038 34 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
nuclear import GO:0051170 3 0.013
response to alkaloid GO:0043279 2 0.013
system process GO:0003008 185 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
camera type eye development GO:0043010 222 0.013
maintenance of location GO:0051235 4 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
histone h4 k20 methylation GO:0034770 2 0.013
regulation of cell division GO:0051302 12 0.013
cellular protein complex disassembly GO:0043624 1 0.013
tissue regeneration GO:0042246 74 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
pancreas development GO:0031016 84 0.013
eye morphogenesis GO:0048592 144 0.013
cellular response to stress GO:0033554 62 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
cardiac atrium development GO:0003230 4 0.013
cell proliferation GO:0008283 80 0.013
positive regulation of molecular function GO:0044093 33 0.013
regulation of binding GO:0051098 3 0.012
nuclear envelope organization GO:0006998 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
response to amphetamine GO:0001975 1 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of protein metabolic process GO:0051247 23 0.012
renal filtration GO:0097205 10 0.012
protein localization GO:0008104 40 0.012
reciprocal dna recombination GO:0035825 1 0.012
regulation of histone h3 k9 methylation GO:0051570 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
cellular component biogenesis GO:0044085 178 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
protein import into nucleus GO:0006606 3 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
angiogenesis GO:0001525 158 0.012
urogenital system development GO:0001655 97 0.011
oxidation reduction process GO:0055114 41 0.011
protein complex disassembly GO:0043241 1 0.011
developmental process involved in reproduction GO:0003006 27 0.011
reciprocal meiotic recombination GO:0007131 1 0.011
regulation of catalytic activity GO:0050790 55 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
protein stabilization GO:0050821 2 0.011
multi organism process GO:0051704 134 0.011
dna alkylation GO:0006305 8 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of dna metabolic process GO:0051052 11 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.011
cell projection morphogenesis GO:0048858 244 0.011
regulation of growth GO:0040008 42 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
protein localization to nucleus GO:0034504 3 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
protein localization to microtubule cytoskeleton GO:0072698 1 0.011
digestive tract development GO:0048565 265 0.011
spermatid development GO:0007286 2 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
histone h3 k4 methylation GO:0051568 2 0.010
positive regulation of catalytic activity GO:0043085 25 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
sister chromatid segregation GO:0000819 6 0.010
zymogen activation GO:0031638 3 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
actomyosin structure organization GO:0031032 53 0.010
regulation of protein targeting GO:1903533 2 0.010
cellular catabolic process GO:0044248 27 0.010

krcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.040
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010