Danio rerio

0 known processes

lars

leucyl-tRNA synthetase

(Aliases: cb667,wu:fb36b12)

lars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.985
Worm
rna metabolic process GO:0016070 219 0.656
cellular macromolecule biosynthetic process GO:0034645 224 0.518
embryo development ending in birth or egg hatching GO:0009792 271 0.489
Worm
gene expression GO:0010467 252 0.433
nitrogen compound metabolic process GO:0006807 319 0.394
nucleic acid metabolic process GO:0090304 244 0.352
mitochondrion morphogenesis GO:0070584 2 0.335
cellular response to topologically incorrect protein GO:0035967 2 0.313
regulation of gene expression GO:0010468 265 0.313
heterocycle metabolic process GO:0046483 290 0.291
histone modification GO:0016570 20 0.260
cellular nitrogen compound metabolic process GO:0034641 290 0.254
macromolecule biosynthetic process GO:0009059 227 0.248
cellular macromolecule metabolic process GO:0044260 391 0.219
organic cyclic compound metabolic process GO:1901360 301 0.214
cell migration GO:0016477 237 0.180
regulation of macromolecule biosynthetic process GO:0010556 225 0.175
sister chromatid cohesion GO:0007062 2 0.158
rna biosynthetic process GO:0032774 181 0.154
death GO:0016265 121 0.144
cellular response to unfolded protein GO:0034620 2 0.142
regulation of cellular metabolic process GO:0031323 320 0.137
lipid storage GO:0019915 1 0.127
regulation of primary metabolic process GO:0080090 311 0.126
heterocycle biosynthetic process GO:0018130 215 0.121
response to stress GO:0006950 263 0.120
cellular aromatic compound metabolic process GO:0006725 295 0.120
transcription dna templated GO:0006351 181 0.119
organonitrogen compound metabolic process GO:1901564 74 0.117
regulation of transcription dna templated GO:0006355 213 0.116
determination of bilateral symmetry GO:0009855 204 0.114
aromatic compound biosynthetic process GO:0019438 217 0.113
cell death GO:0008219 121 0.110
organic cyclic compound biosynthetic process GO:1901362 223 0.108
oxidative phosphorylation GO:0006119 1 0.107
biosynthetic process GO:0009058 294 0.106
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.102
cellular biosynthetic process GO:0044249 286 0.101
regulation of multicellular organism growth GO:0040014 4 0.099
regulation of biosynthetic process GO:0009889 250 0.092
protein acetylation GO:0006473 2 0.092
single organism organelle organization GO:1902589 199 0.089
regulation of cellular biosynthetic process GO:0031326 245 0.088
b cell activation GO:0042113 2 0.087
endoplasmic reticulum unfolded protein response GO:0030968 2 0.086
response to topologically incorrect protein GO:0035966 2 0.083
nucleobase containing compound metabolic process GO:0006139 274 0.079
cellular nitrogen compound biosynthetic process GO:0044271 218 0.077
regulation of nucleic acid templated transcription GO:1903506 213 0.076
regulation of developmental process GO:0050793 247 0.075
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.075
single organism metabolic process GO:0044710 217 0.073
cellular protein metabolic process GO:0044267 129 0.071
internal protein amino acid acetylation GO:0006475 2 0.070
developmental growth GO:0048589 166 0.068
regulation of nitrogen compound metabolic process GO:0051171 251 0.068
protein modification process GO:0036211 100 0.067
nucleobase containing compound biosynthetic process GO:0034654 205 0.066
response to chemical GO:0042221 320 0.066
multicellular organism growth GO:0035264 4 0.065
regulation of metabolic process GO:0019222 359 0.061
macromolecule modification GO:0043412 111 0.061
regulation of response to stimulus GO:0048583 269 0.059
transcription from rna polymerase ii promoter GO:0006366 80 0.059
peptidyl lysine acetylation GO:0018394 2 0.058
determination of left right symmetry GO:0007368 179 0.057
nucleic acid templated transcription GO:0097659 181 0.053
amine metabolic process GO:0009308 2 0.053
transport GO:0006810 220 0.051
response to abiotic stimulus GO:0009628 122 0.049
response to external stimulus GO:0009605 264 0.048
regulation of rna metabolic process GO:0051252 224 0.047
cellular response to stress GO:0033554 62 0.047
system process GO:0003008 185 0.047
maintenance of location GO:0051235 4 0.047
cellular protein modification process GO:0006464 100 0.046
protein secretion GO:0009306 1 0.045
nuclear division GO:0000280 23 0.044
organelle organization GO:0006996 227 0.041
protein metabolic process GO:0019538 183 0.040
er nucleus signaling pathway GO:0006984 2 0.040
specification of symmetry GO:0009799 204 0.039
response to unfolded protein GO:0006986 2 0.039
aging GO:0007568 2 0.039
organic substance biosynthetic process GO:1901576 289 0.038
cellular component biogenesis GO:0044085 178 0.038
cellular localization GO:0051641 97 0.038
cell motility GO:0048870 244 0.038
small molecule metabolic process GO:0044281 77 0.036
regulation of rna biosynthetic process GO:2001141 213 0.036
cellular amine metabolic process GO:0044106 2 0.033
internal peptidyl lysine acetylation GO:0018393 2 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
negative regulation of cellular process GO:0048523 283 0.032
programmed cell death GO:0012501 119 0.031
establishment of localization GO:0051234 244 0.031
locomotion GO:0040011 313 0.031
covalent chromatin modification GO:0016569 20 0.031
intracellular estrogen receptor signaling pathway GO:0030520 3 0.030
gtp catabolic process GO:0006184 2 0.030
regulation of signal transduction GO:0009966 225 0.029
taxis GO:0042330 109 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
mitochondrion organization GO:0007005 4 0.027
protein acylation GO:0043543 3 0.027
signal transduction GO:0007165 455 0.027
response to organic substance GO:0010033 153 0.025
multi organism process GO:0051704 134 0.024
behavior GO:0007610 74 0.024
neuron projection morphogenesis GO:0048812 161 0.023
purine ribonucleoside metabolic process GO:0046128 10 0.023
cell part morphogenesis GO:0032990 246 0.023
positive regulation of biological process GO:0048518 253 0.023
b cell mediated immunity GO:0019724 3 0.023
regulation of protein ubiquitination GO:0031396 3 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
single organism transport GO:0044765 206 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
dna catabolic process GO:0006308 1 0.022
regulation of organelle assembly GO:1902115 4 0.021
ribonucleotide metabolic process GO:0009259 27 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
mitotic cell cycle GO:0000278 64 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
growth GO:0040007 174 0.021
histone deacetylation GO:0016575 2 0.021
establishment of localization in cell GO:0051649 77 0.020
organic acid metabolic process GO:0006082 31 0.020
central nervous system development GO:0007417 387 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
regulation of cell communication GO:0010646 232 0.019
transmission of nerve impulse GO:0019226 19 0.019
chromosome organization GO:0051276 31 0.019
chromatin organization GO:0006325 22 0.019
single organism localization GO:1902578 225 0.019
mesoderm development GO:0007498 88 0.018
positive regulation of metabolic process GO:0009893 108 0.018
post embryonic development GO:0009791 7 0.018
Worm
establishment of organelle localization GO:0051656 45 0.018
nucleoside phosphate metabolic process GO:0006753 28 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
positive regulation of cell cycle GO:0045787 3 0.017
negative regulation of biological process GO:0048519 304 0.016
regulation of programmed cell death GO:0043067 101 0.016
axon ensheathment in central nervous system GO:0032291 2 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
lipid catabolic process GO:0016042 4 0.016
cell aging GO:0007569 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of growth GO:0040008 42 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
cellular response to organic substance GO:0071310 105 0.015
apoptotic process GO:0006915 116 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
cellular component morphogenesis GO:0032989 336 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
negative regulation of cell growth GO:0030308 7 0.014
reproductive process GO:0022414 40 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
b cell proliferation GO:0042100 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
response to hypoxia GO:0001666 25 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
organic substance catabolic process GO:1901575 28 0.013
macromolecule deacylation GO:0098732 3 0.013
nucleoside triphosphate biosynthetic process GO:0009142 2 0.013
cellular component movement GO:0006928 335 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
chemotaxis GO:0006935 104 0.013
cellular response to oxygen levels GO:0071453 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
endocytosis GO:0006897 16 0.012
insulin like growth factor receptor signaling pathway GO:0048009 4 0.012
regulation of peptidase activity GO:0052547 23 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
axonogenesis GO:0007409 152 0.012
regulation of biological quality GO:0065008 263 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
nuclear export GO:0051168 1 0.012
regulation of cell death GO:0010941 103 0.012
regulation of gtp catabolic process GO:0033124 2 0.011
tissue regeneration GO:0042246 74 0.011
regulation of gtpase activity GO:0043087 2 0.011
hemopoiesis GO:0030097 183 0.011
regulation of signaling GO:0023051 235 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
organelle localization GO:0051640 49 0.011
nucleoside phosphate biosynthetic process GO:1901293 21 0.011
germ cell development GO:0007281 22 0.011
regeneration GO:0031099 91 0.011
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.011
ncrna metabolic process GO:0034660 12 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
purine containing compound metabolic process GO:0072521 29 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
neurological system process GO:0050877 62 0.010
organophosphate metabolic process GO:0019637 37 0.010
cellular component assembly GO:0022607 170 0.010
centrosome duplication GO:0051298 1 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010

lars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.189
nervous system disease DOID:863 0 0.066
neuromuscular disease DOID:440 0 0.057
charcot marie tooth disease DOID:10595 0 0.057
neuropathy DOID:870 0 0.057
musculoskeletal system disease DOID:17 0 0.022
charcot marie tooth disease type 2 DOID:0050539 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.010
cancer DOID:162 0 0.010
thoracic cancer DOID:5093 0 0.010