Danio rerio

0 known processes

ldhba

lactate dehydrogenase Ba

(Aliases: LDH-B-A,wu:fa16d07,wu:fa96a08,ldhb,wu:fa20c10)

ldhba biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.399
larval development GO:0002164 2 0.300
small molecule metabolic process GO:0044281 77 0.238
central nervous system development GO:0007417 387 0.228
dicarboxylic acid metabolic process GO:0043648 1 0.209
cellular modified amino acid metabolic process GO:0006575 3 0.208
nitrogen compound metabolic process GO:0006807 319 0.190
response to external stimulus GO:0009605 264 0.188
cellular component morphogenesis GO:0032989 336 0.177
neuron differentiation GO:0030182 353 0.175
neuron development GO:0048666 262 0.149
actin filament based process GO:0030029 64 0.148
muscle cell differentiation GO:0042692 139 0.141
cellular respiration GO:0045333 3 0.132
oxidation reduction process GO:0055114 41 0.128
small molecule catabolic process GO:0044282 3 0.127
organic acid metabolic process GO:0006082 31 0.123
hydrogen peroxide metabolic process GO:0042743 2 0.122
carboxylic acid metabolic process GO:0019752 22 0.118
carboxylic acid catabolic process GO:0046395 3 0.113
organic acid catabolic process GO:0016054 3 0.109
organic substance biosynthetic process GO:1901576 289 0.100
response to chemical GO:0042221 320 0.095
generation of neurons GO:0048699 385 0.094
cellular component assembly GO:0022607 170 0.093
single organism biosynthetic process GO:0044711 71 0.091
organelle organization GO:0006996 227 0.091
myosin filament organization GO:0031033 6 0.085
cellular nitrogen compound metabolic process GO:0034641 290 0.084
regulation of primary metabolic process GO:0080090 311 0.082
alpha amino acid metabolic process GO:1901605 3 0.079
maintenance of location GO:0051235 4 0.077
muscle cell development GO:0055001 115 0.076
single organism metabolic process GO:0044710 217 0.074
negative regulation of kinase activity GO:0033673 4 0.071
response to organic substance GO:0010033 153 0.069
cell surface receptor signaling pathway GO:0007166 325 0.068
cellular amino acid biosynthetic process GO:0008652 2 0.067
aromatic compound biosynthetic process GO:0019438 217 0.066
establishment of localization GO:0051234 244 0.066
adult behavior GO:0030534 2 0.066
brain development GO:0007420 293 0.066
response to hydrogen peroxide GO:0042542 3 0.065
macromolecular complex subunit organization GO:0043933 74 0.065
organonitrogen compound metabolic process GO:1901564 74 0.065
regulation of biological quality GO:0065008 263 0.064
regulation of multicellular organismal process GO:0051239 277 0.062
cellular response to chemical stimulus GO:0070887 157 0.062
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
response to drug GO:0042493 3 0.059
cellular component assembly involved in morphogenesis GO:0010927 107 0.055
lateral inhibition GO:0046331 1 0.054
alcohol biosynthetic process GO:0046165 2 0.054
cellular macromolecule metabolic process GO:0044260 391 0.053
cytoskeleton organization GO:0007010 96 0.052
transport GO:0006810 220 0.052
negative regulation of biological process GO:0048519 304 0.052
cellular amino acid metabolic process GO:0006520 7 0.052
regulation of multicellular organism growth GO:0040014 4 0.050
neurotransmitter transport GO:0006836 2 0.050
organelle assembly GO:0070925 110 0.050
leukocyte proliferation GO:0070661 1 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.048
fatty acid transport GO:0015908 1 0.048
negative regulation of protein kinase activity GO:0006469 4 0.048
system process GO:0003008 185 0.047
locomotion GO:0040011 313 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.046
nucleobase containing compound metabolic process GO:0006139 274 0.046
electron transport chain GO:0022900 2 0.045
cell migration GO:0016477 237 0.045
phosphorus metabolic process GO:0006793 109 0.045
regulation of cellular response to oxidative stress GO:1900407 2 0.044
striated muscle cell differentiation GO:0051146 129 0.044
carbohydrate biosynthetic process GO:0016051 1 0.044
myosin filament assembly GO:0031034 6 0.043
cellular component biogenesis GO:0044085 178 0.042
muscle structure development GO:0061061 196 0.042
regulation of transcription dna templated GO:0006355 213 0.042
actin cytoskeleton organization GO:0030036 63 0.042
myofibril assembly GO:0030239 48 0.041
response to stress GO:0006950 263 0.041
Zebrafish
protein acetylation GO:0006473 2 0.041
axon development GO:0061564 166 0.041
regulation of developmental process GO:0050793 247 0.041
response to oxygen radical GO:0000305 2 0.040
heart development GO:0007507 313 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.039
neurotransmitter secretion GO:0007269 2 0.039
regulation of apoptotic process GO:0042981 98 0.039
negative regulation of apoptotic process GO:0043066 55 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.038
cytokinesis GO:0000910 3 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
response to superoxide GO:0000303 2 0.037
oxoacid metabolic process GO:0043436 31 0.037
cell aging GO:0007569 2 0.037
cell death GO:0008219 121 0.037
regulation of cell differentiation GO:0045595 142 0.036
transcription dna templated GO:0006351 181 0.036
pigmentation GO:0043473 85 0.035
neuroblast proliferation GO:0007405 2 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
negative regulation of programmed cell death GO:0043069 58 0.033
nucleocytoplasmic transport GO:0006913 4 0.033
amine metabolic process GO:0009308 2 0.033
removal of superoxide radicals GO:0019430 2 0.032
cellular component movement GO:0006928 335 0.032
protein complex assembly GO:0006461 30 0.032
gtp metabolic process GO:0046039 4 0.032
regulation of autophagy GO:0010506 3 0.032
protein acylation GO:0043543 3 0.031
regulation of binding GO:0051098 3 0.031
catechol containing compound metabolic process GO:0009712 2 0.031
cellular biosynthetic process GO:0044249 286 0.031
phagocytosis GO:0006909 3 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
response to nutrient GO:0007584 3 0.031
negative regulation of mapk cascade GO:0043409 4 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
cell cell signaling GO:0007267 52 0.031
nuclear transport GO:0051169 4 0.031
single organism organelle organization GO:1902589 199 0.031
multi organism process GO:0051704 134 0.030
biosynthetic process GO:0009058 294 0.030
cell part morphogenesis GO:0032990 246 0.030
response to radiation GO:0009314 51 0.030
cell motility GO:0048870 244 0.030
blood circulation GO:0008015 87 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of response to oxidative stress GO:1902882 2 0.029
detection of stimulus GO:0051606 29 0.028
mitochondrion organization GO:0007005 4 0.028
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.028
regulation of nervous system development GO:0051960 90 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
multicellular organism growth GO:0035264 4 0.028
cellular ketone metabolic process GO:0042180 11 0.027
cellular aldehyde metabolic process GO:0006081 4 0.027
cell projection morphogenesis GO:0048858 244 0.027
signal transduction GO:0007165 455 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
macromolecule modification GO:0043412 111 0.026
nucleic acid templated transcription GO:0097659 181 0.026
striated muscle myosin thick filament assembly GO:0071688 6 0.026
behavior GO:0007610 74 0.026
autophagy GO:0006914 4 0.026
response to abiotic stimulus GO:0009628 122 0.026
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
response to other organism GO:0051707 97 0.025
multicellular organismal metabolic process GO:0044236 2 0.025
energy reserve metabolic process GO:0006112 2 0.025
regulation of metabolic process GO:0019222 359 0.025
neuron projection morphogenesis GO:0048812 161 0.025
regulation of programmed cell death GO:0043067 101 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
negative regulation of cellular process GO:0048523 283 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
proteolysis GO:0006508 38 0.024
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.024
spermatid differentiation GO:0048515 2 0.024
neuron neuron synaptic transmission GO:0007270 1 0.024
protein complex biogenesis GO:0070271 30 0.024
negative regulation of signaling GO:0023057 96 0.024
carbohydrate derivative metabolic process GO:1901135 61 0.024
embryonic organ morphogenesis GO:0048562 274 0.023
regulation of neurogenesis GO:0050767 87 0.023
response to endogenous stimulus GO:0009719 83 0.023
respiratory electron transport chain GO:0022904 2 0.023
actin filament polymerization GO:0030041 2 0.023
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.023
protein localization to plasma membrane GO:0072659 1 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
organophosphate metabolic process GO:0019637 37 0.023
cellular macromolecular complex assembly GO:0034622 24 0.023
gene expression GO:0010467 252 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
striated muscle cell development GO:0055002 108 0.022
regulation of protein polymerization GO:0032271 2 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
cellular amide metabolic process GO:0043603 4 0.022
cellular response to oxygen radical GO:0071450 2 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
regulation of dna templated transcription in response to stress GO:0043620 0 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
regulation of reactive oxygen species metabolic process GO:2000377 2 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
hepaticobiliary system development GO:0061008 98 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.021
astrocyte differentiation GO:0048708 1 0.021
cellular amine metabolic process GO:0044106 2 0.021
sulfur compound metabolic process GO:0006790 13 0.021
regulation of blood vessel size GO:0050880 2 0.021
somatic muscle development GO:0007525 4 0.021
response to copper ion GO:0046688 13 0.021
regulation of reproductive process GO:2000241 4 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
regulation of cell activation GO:0050865 1 0.021
protein homooligomerization GO:0051260 3 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
immune system process GO:0002376 241 0.021
catabolic process GO:0009056 32 0.020
gtp catabolic process GO:0006184 2 0.020
monovalent inorganic cation transport GO:0015672 42 0.020
stem cell proliferation GO:0072089 4 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
xenobiotic metabolic process GO:0006805 4 0.020
response to light stimulus GO:0009416 46 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
gland development GO:0048732 143 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.019
nuclear import GO:0051170 3 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
negative regulation of catabolic process GO:0009895 3 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
single organism transport GO:0044765 206 0.019
cellular response to reactive oxygen species GO:0034614 2 0.019
neuron projection development GO:0031175 180 0.019
developmental growth GO:0048589 166 0.019
homeostatic process GO:0042592 142 0.019
actomyosin structure organization GO:0031032 53 0.019
apoptotic process GO:0006915 116 0.019
response to oxygen containing compound GO:1901700 55 0.019
positive regulation of transport GO:0051050 2 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
head development GO:0060322 303 0.019
cell projection organization GO:0030030 284 0.018
regulation of blood pressure GO:0008217 1 0.018
response to reactive oxygen species GO:0000302 5 0.018
oocyte anterior posterior axis specification GO:0007314 4 0.018
cellular response to organic substance GO:0071310 105 0.018
nitric oxide metabolic process GO:0046209 2 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
response to transition metal nanoparticle GO:1990267 28 0.018
superoxide metabolic process GO:0006801 2 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
regulation of molecular function GO:0065009 70 0.018
death GO:0016265 121 0.018
cellular component disassembly GO:0022411 1 0.018
lipid storage GO:0019915 1 0.018
vesicle mediated transport GO:0016192 22 0.018
catecholamine biosynthetic process GO:0042423 2 0.018
cell morphogenesis GO:0000902 289 0.018
negative regulation of map kinase activity GO:0043407 2 0.018
negative regulation of sequestering of calcium ion GO:0051283 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
positive regulation of cellular process GO:0048522 201 0.018
positive regulation of biological process GO:0048518 253 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
response to wounding GO:0009611 116 0.018
regulation of tube size GO:0035150 2 0.017
organic substance catabolic process GO:1901575 28 0.017
locomotory behavior GO:0007626 34 0.017
multicellular organismal homeostasis GO:0048871 29 0.017
nucleobase containing small molecule metabolic process GO:0055086 32 0.017
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.017
purine nucleotide metabolic process GO:0006163 27 0.017
nuclear migration GO:0007097 3 0.017
protein localization to nucleus GO:0034504 3 0.017
programmed cell death GO:0012501 119 0.017
protein stabilization GO:0050821 2 0.017
ribose phosphate metabolic process GO:0019693 27 0.017
myotube differentiation GO:0014902 45 0.017
striated muscle tissue development GO:0014706 110 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
neurological system process GO:0050877 62 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
positive regulation of cell differentiation GO:0045597 30 0.016
regulation of oocyte development GO:0060281 3 0.016
rna biosynthetic process GO:0032774 181 0.016
regulation of membrane potential GO:0042391 23 0.016
axonogenesis GO:0007409 152 0.016
axon guidance GO:0007411 86 0.016
phototransduction GO:0007602 2 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
guanosine containing compound catabolic process GO:1901069 2 0.015
branched chain amino acid metabolic process GO:0009081 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
protein complex subunit organization GO:0071822 46 0.015
cellular protein modification process GO:0006464 100 0.015
microtubule based movement GO:0007018 33 0.015
organic acid biosynthetic process GO:0016053 12 0.015
response to inorganic substance GO:0010035 38 0.015
phenol containing compound biosynthetic process GO:0046189 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
response to external biotic stimulus GO:0043207 97 0.015
cellular response to oxygen levels GO:0071453 1 0.015
protein metabolic process GO:0019538 183 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of cell development GO:0060284 100 0.015
protein polymerization GO:0051258 4 0.015
pyruvate metabolic process GO:0006090 1 0.015
protein import GO:0017038 3 0.015
regulation of circadian rhythm GO:0042752 4 0.015
growth GO:0040007 174 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
negative regulation of signal transduction GO:0009968 94 0.014
regulation of signal transduction GO:0009966 225 0.014
pole plasm assembly GO:0007315 4 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
catecholamine metabolic process GO:0006584 2 0.014
response to corticosteroid GO:0031960 1 0.014
intracellular signal transduction GO:0035556 85 0.014
response to hexose GO:0009746 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
membrane invagination GO:0010324 1 0.014
cellular response to superoxide GO:0071451 2 0.014
cellular response to oxidative stress GO:0034599 5 0.014
nitric oxide biosynthetic process GO:0006809 2 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
negative regulation of cytokine production GO:0001818 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
sequestering of calcium ion GO:0051208 3 0.014
establishment of blood brain barrier GO:0060856 2 0.013
heart morphogenesis GO:0003007 156 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
regulation of cell death GO:0010941 103 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
estrogen metabolic process GO:0008210 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
circulatory system process GO:0003013 87 0.013
regulation of endopeptidase activity GO:0052548 23 0.013
response to monosaccharide GO:0034284 3 0.013
liver development GO:0001889 96 0.013
iron ion homeostasis GO:0055072 4 0.013
purine containing compound metabolic process GO:0072521 29 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
macromolecular complex disassembly GO:0032984 1 0.013
protein targeting to nucleus GO:0044744 3 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
regulation of protein binding GO:0043393 3 0.012
segmentation GO:0035282 97 0.012
hemopoiesis GO:0030097 183 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
response to oxidative stress GO:0006979 11 0.012
response to biotic stimulus GO:0009607 97 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
regulation of rna metabolic process GO:0051252 224 0.012
positive regulation of metabolic process GO:0009893 108 0.012
protein import into nucleus GO:0006606 3 0.012
atp catabolic process GO:0006200 4 0.012
embryonic organ development GO:0048568 381 0.012
axon cargo transport GO:0008088 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
response to carbohydrate GO:0009743 3 0.012
somite development GO:0061053 96 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
response to organic cyclic compound GO:0014070 51 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
response to hormone GO:0009725 48 0.012
camera type eye development GO:0043010 222 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
positive regulation of glial cell differentiation GO:0045687 1 0.012
macromolecular complex assembly GO:0065003 35 0.012
zymogen activation GO:0031638 3 0.012
negative regulation of cell death GO:0060548 60 0.012
dopamine metabolic process GO:0042417 2 0.012
response to uv GO:0009411 3 0.011
response to food GO:0032094 1 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
regulation of protein metabolic process GO:0051246 56 0.011
negative regulation of molecular function GO:0044092 23 0.011
muscle tissue development GO:0060537 110 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
pyrimidine containing compound metabolic process GO:0072527 3 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
thermosensory behavior GO:0040040 1 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
lymphocyte proliferation GO:0046651 1 0.011
negative regulation of cell communication GO:0010648 96 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
fatty acid oxidation GO:0019395 1 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
regulation of protein transport GO:0051223 3 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of response to stress GO:0080134 36 0.011
reactive oxygen species metabolic process GO:0072593 6 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
b cell activation GO:0042113 2 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
lipid metabolic process GO:0006629 52 0.011
cellular response to lipid GO:0071396 39 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
heterocycle metabolic process GO:0046483 290 0.011
regulation of gtpase activity GO:0043087 2 0.011
axon ensheathment in central nervous system GO:0032291 2 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
monoamine transport GO:0015844 1 0.010
nucleotide metabolic process GO:0009117 28 0.010
chemotaxis GO:0006935 104 0.010
regulation of cell shape GO:0008360 1 0.010
reproduction GO:0000003 40 0.010
phosphorylation GO:0016310 69 0.010
regulation of peptidase activity GO:0052547 23 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
positive regulation of blood circulation GO:1903524 2 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010

ldhba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.074
inherited metabolic disorder DOID:655 0 0.074
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
mitochondrial metabolism disease DOID:700 0 0.012